Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Presence of thoracic and lumbar vertebral malformations in pugs with and without chronic neurological deficits
Swedish Univ Agr Sci, Dept Clin Sci, S-75007 Uppsala, Sweden;Albano Small Anim Hosp, Anicura, Rinkebyvagen 21, S-18236 Danderyd, Sweden.
Swedish Univ Agr Sci, Dept Clin Sci, S-75007 Uppsala, Sweden.
Swedish Univ Agr Sci, Dept Clin Sci, S-75007 Uppsala, Sweden.
Bagarmossen Small Anim Hosp, Anicura, Ljusnevagen 17, S-12848 Bagarmossen, Sweden.
Show others and affiliations
2018 (English)In: The Veterinary Journal, ISSN 1090-0233, E-ISSN 1532-2971, Vol. 241, p. 24-30Article in journal (Refereed) Published
Abstract [en]

Congenital vertebral malformations (CVMs) are common in brachycephalic dogs such as the pug, and are often considered incidental findings. However, specific CVMs have been suggested to be associated with neurological deficits in pugs. The objective of this study was to investigate the clinical importance of CVMs in the pug by comparing computed tomography studies of the thoracolumbar spine from pugs without neurological deficits with those from pugs with a confirmed T3-L3 spinal cord lesion and neurological deficits consistent with a chronic T3-L3 myelopathy. A total of 57 pugs were recruited into the study from Sweden (n=33), United Kingdom (n=21) and Norway (n = 3); 30 with neurological deficits and 27 without. Focal T3-L3 pathology was confirmed in all pugs with neurological deficits by magnetic resonance imaging (n = 29) and/or pathology (n = 15). Computed tomography studies of the thoracolumbar spine from pugs with and without neurological deficits were compared to investigate possible associations between presentation of neurological deficits consistent with chronic T3-L3 pathology and signalment variables, presence of CVMs and type of CVMs. Congenital vertebral malformations were as common in pugs with, as in pugs without, neurological deficits. Regardless of neurological status, the majority of pugs (96%) presented with one or more CVM. An association between presence, or type of CVM in the T1-L3 vertebral column, and neurological deficits consistent with T3-L3 pathology could not be confirmed.

Place, publisher, year, edition, pages
2018. Vol. 241, p. 24-30
Keywords [en]
Caudal articular processes, Cr, Hemivertebrae, Myelopathy, Transitional vertebrae
National Category
Other Veterinary Science
Identifiers
URN: urn:nbn:se:uu:diva-369598DOI: 10.1016/j.tvjl.2018.09.008ISI: 000449127400004PubMedID: 30340656OAI: oai:DiVA.org:uu-369598DiVA, id: diva2:1272412
Available from: 2018-12-19 Created: 2018-12-19 Last updated: 2018-12-19Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Lindblad-Toh, Kerstin
By organisation
Department of Medical Biochemistry and MicrobiologyScience for Life Laboratory, SciLifeLab
In the same journal
The Veterinary Journal
Other Veterinary Science

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 338 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf