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A ß-Glucan-Based Dietary Fiber Reduces Mast Cell-Induced Hyperpermeability in Ileum From Patients With Crohns Disease and Control Subjects
School of Medical Sciences, Nutrition-Gut-Brain Interactions Research Centre, Örebro University, Örebro, Sweden.
Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för Kirurgi, Ortopedi och Onkologi. Linköpings universitet, Medicinska fakulteten.
Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för Kirurgi, Ortopedi och Onkologi. Linköpings universitet, Medicinska fakulteten.
School of Medical Sciences, Nutrition-Gut-Brain Interactions Research Centre, Örebro University, Örebro, Sweden.
Vise andre og tillknytning
2018 (engelsk)Inngår i: Inflammatory Bowel Diseases, ISSN 1078-0998, E-ISSN 1536-4844, Vol. 24, nr 1, s. 166-178Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Administration of ß-glucan has shown immune-enhancing effects. Our aim was to investigate whether ß-glucan could attenuate mast cell (MC)-induced hyperpermeability in follicle-associated epithelium (FAE) and villus epithelium (VE) of patients with Crohns disease (CD) and in noninflammatory bowel disease (IBD)-controls. Further, we studied mechanisms of ß-glucan uptake and effects on MCs in vitro.

sted, utgiver, år, opplag, sider
Lippincott Williams & Wilkins, 2018. Vol. 24, nr 1, s. 166-178
Emneord [en]
Crohn’s disease; intestinal permeability; ß-glucan
HSV kategori
Identifikatorer
URN: urn:nbn:se:liu:diva-146363DOI: 10.1093/ibd/izx002ISI: 000427524400018PubMedID: 29272475OAI: oai:DiVA.org:liu-146363DiVA, id: diva2:1195985
Tilgjengelig fra: 2018-04-07 Laget: 2018-04-07 Sist oppdatert: 2019-04-09

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