Sexual dysfunction in women on adjuvant endocrine therapy after breast cancerVise andre og tillknytning
2013 (engelsk)Inngår i: Menopause: The Journal of the North American Menopause, ISSN 1072-3714, E-ISSN 1530-0374, Vol. 20, nr 2, s. 162-168Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]
Objective: The goal of this study was to investigate sexual function in postmenopausal breast cancer patients treated with aromatase inhibitors.
Methods: A population-based, cross-sectional study was conducted among postmenopausal breast cancer patients on adjuvant endocrine treatment and age-matched controls with and without estrogen treatment. Sexual function was assessed with a standardized questionnaire.
Results: In all, 42.4% of aromatase inhibitor-treated breast cancer patients were dissatisfied with their sex life in general, and 50.0% reported low sexual interest; this was significantly more common than in tamoxifen-treated patients and controls (P < 0.05). Aromatase inhibitorYtreated patients reported insufficient lubrication in 73.9% and dyspareunia in 56.5% of cases, which were significantly more common than in controls, irrespective of hormonal use (P < 0.05). Tamoxifen-treated patients reported significantly more dyspareunia (31.3%; P < 0.05) but resembled controls in all other concerns.
Conclusions: Our findings suggest that sexual dysfunction in aromatase inhibitorYtreated women is a greatly underestimated problem.
sted, utgiver, år, opplag, sider
Lippincott Williams & Wilkins, 2013. Vol. 20, nr 2, s. 162-168
Emneord [en]
Aromatase inhibitors, Breast cancer, Postmenopausal women, Sexual dysfunction, Tamoxifen
HSV kategori
Identifikatorer
URN: urn:nbn:se:oru:diva-54872DOI: 10.1097/gme.0b013e31826560daISI: 000314342600010PubMedID: 22990756Scopus ID: 2-s2.0-84873409411OAI: oai:DiVA.org:oru-54872DiVA, id: diva2:1066943
Forskningsfinansiär
Swedish Cancer Society, CAN 2009/773Swedish Research Council, VR 621-2008-3562
Merknad
Funding Agency:
Uppsala-Örebro Regional Research Council
Lions Clubs International
Percy Falk Foundation
2017-01-192017-01-192020-12-01bibliografisk kontrollert