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Comparison of joint status with ultrasound and physical examination in children with hemophilia A
Umeå universitet, Medicinska fakulteten, Institutionen för samhällsmedicin och rehabilitering, Fysioterapi.
2016 (engelsk)Independent thesis Advanced level (degree of Master (Two Years)), 20 poäng / 30 hpOppgave
Abstract [en]

Introduction: Hemophilia A is a bleeding disorder that can cause chronic artropathy, when not treated optimally. To detect early signs of hemophilic artropathy patients with moderate or severe hemophilia undergo yearly examinations by a physiotherapist defining the joint status by a scoring system, “HJHS”. A new ultrasound-based scoring system, HEAD-US, has been developed to evaluate joint disease progression and treatment results. The aim of this study is to evaluate if there is a correlation between HJHS 2.1 and HEAD-US in children with hemophilia A. Furthermore, to evaluate if there is a correlation between physical activity and hemophilic artropathy and finally to asses if there are any differences in artropathy between sub-groups within the study group.

Methods: A prospective study where all patients between ages 3 to 18 years with moderate or severe hemophilia followed at the Karolinska University Hospital 2015-2016 were asked to participate. Patients were asked to fill in a questionnaire regarding physical activity and joint bleeds and clinical data were retrospectively collected from the patients’ medical records. Joints were evaluated by the author according to HJHS and HEAD-US.

Results: There was a significant correlation between the total-, elbow-, knee- and ankle scores for HJHS and HEAD-US scores. There was a statistically significant correlation between annual bleeding rate and total scores for HJHS and HEAD-US. No statistically significant correlation was seen between the total score of HJHS or HEAD-US and the level of physical activity.

Conclusions: This study demonstrates that the total score and individual joint scores with HEAD-US correlate well with the current method HJHS 2.1 in children with hemophilia A. 

sted, utgiver, år, opplag, sider
2016. , s. 40
Emneord [en]
Hemofilia a, HJHS, HEAD-US, Pediatric, Hemofilic artropathy
HSV kategori
Identifikatorer
URN: urn:nbn:se:umu:diva-126899OAI: oai:DiVA.org:umu-126899DiVA, id: diva2:1038807
Eksternt samarbeid
Susanna Ranta, Karolinska Universitetssjukhuset, Solna
Utdanningsprogram
Graduate Programme in Physiotherapy
Presentation
2016-09-26, A102, Vårdvetarhuset, Umeå universitet, Umeå, 13:00 (svensk)
Veileder
Examiner
Tilgjengelig fra: 2016-12-28 Laget: 2016-10-19 Sist oppdatert: 2016-12-28bibliografisk kontrollert

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