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Simultaneous determination of endogenous steroid hormones in human and animal plasma and serum by liquid or gas chromatography coupled to tandem mass spectrometry
Institute of Mass Spectrometry, College of Medicine, Swansea University.
Högskolan Kristianstad, Sektionen för lärande och miljö, Avdelningen för Naturvetenskap.
Department of Civil & Environmental Engineering, Stanford University.
2013 (Engelska)Ingår i: Journal of chromatography. B, ISSN 1570-0232, E-ISSN 1873-376X, Vol. 928, nr June, s. 59-77Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Analytical methodologies based on liquid or gas chromatography coupled to tandem mass spectrometry for the simultaneous determination of two or more endogenous steroid hormones in human and animal plasma and serum has received increased attention the last few years. Especially in the clinical setting steroid profiling is of major importance in disease diagnostics. This paper discusses recent findings in such multi-steroid hormone procedures published from 2001 to 2012. The aim was to elucidate possible relationships between chosen analytical technique and the obtained analyte sensitivity for endogenous steroid hormones. By evaluating the success, at which the currently applied techniques have been utilized, more general knowledge on the field is provided. Furthermore the evaluation provides directions in which future studies may be interesting to conduct.

Ort, förlag, år, upplaga, sidor
2013. Vol. 928, nr June, s. 59-77
Nyckelord [en]
Steroid hormones, Plasma, Serum, Liquid chromatography, Gas chromatography, Tandem mass spectrometry
Nationell ämneskategori
Biologiska vetenskaper
Identifikatorer
URN: urn:nbn:se:hkr:diva-10343DOI: 10.1016/j.jchromb.2013.03.013ISI: 000319236700009PubMedID: 23598050OAI: oai:DiVA.org:hkr-10343DiVA, id: diva2:613284
Tillgänglig från: 2013-03-27 Skapad: 2013-03-27 Senast uppdaterad: 2017-12-06Bibliografiskt granskad

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