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Loud Noise Exposure and Acoustic Neuroma
Ohio State University, OH 43201 USA Ohio State University, OH 43201 USA Ohio State University, OH 43201 USA .
Karolinska Institute, Sweden .
Ohio State University, OH 43201 USA .
Ohio State University, OH 43201 USA Ohio State University, OH 43201 USA Ohio State University, OH 43201 USA Ohio State University, OH 43201 USA .
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2014 (Engelska)Ingår i: American Journal of Epidemiology, ISSN 0002-9262, E-ISSN 1476-6256, Vol. 180, nr 1, s. 58-67Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

The results from studies of loud noise exposure and acoustic neuroma are conflicting. A population-based case-control study of 451 acoustic neuroma patients and 710 age-, sex-, and region-matched controls was conducted in Sweden between 2002 and 2007. Occupational exposure was based on historical measurements of occupational noise (321 job titles summarized by a job exposure matrix) and compared with self-reported occupational noise exposure. We also evaluated self-reported noise exposure during leisure activity. Conditional logistic regression was used to estimate odds ratios. There was no statistically significant association between acoustic neuroma and persistent occupational noise exposure, either with or without hearing protection. Exposure to loud noise from leisure activity without hearing protection was more common among acoustic neuroma cases (odds ratio = 1.47, 95% confidence interval: 1.06, 2.03). Statistically significant odds ratios were found for specific leisure activities including attending concerts/clubs/sporting events (odds ratio = 1.82, 95% confidence interval: 1.09, 3.04) and participating in workouts accompanied by loud music (odds ratio = 2.84, 95% confidence interval: 1.37, 5.89). Our findings do not support an association between occupational exposure to loud noise and acoustic neuroma. Although we report statistically significant associations between leisure-time exposures to loud noise without hearing protection and acoustic neuroma, especially among women, we cannot rule out recall bias as an alternative explanation.

Ort, förlag, år, upplaga, sidor
Oxford University Press (OUP): Policy B - Oxford Open Option B , 2014. Vol. 180, nr 1, s. 58-67
Nyckelord [en]
acoustic neuroma; noise; occupation; vestibular schwannoma
Nationell ämneskategori
Klinisk medicin
Identifikatorer
URN: urn:nbn:se:liu:diva-109887DOI: 10.1093/aje/kwu081ISI: 000339808200009PubMedID: 24786799OAI: oai:DiVA.org:liu-109887DiVA, id: diva2:741565
Anmärkning

Funding Agencies|Swedish Council for Working Life and Social Research; Ohio State University James Cancer Hospital; Solove Research Institute

Tillgänglig från: 2014-08-28 Skapad: 2014-08-28 Senast uppdaterad: 2017-12-05

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Harder, Henrik
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Avdelningen för neurovetenskapHälsouniversitetetÖron- näsa- och halskliniken US
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American Journal of Epidemiology
Klinisk medicin

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