Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Christmas, national holidays, sport events, and time factors as triggers of acute myocardial infarction: SWEDEHEART observational study 1998-2013
Lund Univ, Skane Univ Hosp, Dept Cardiol, Clin Sci, Lund, Sweden.
Lund Univ, Skane Univ Hosp, Dept Cardiol, Clin Sci, Lund, Sweden.
Lund Univ, Skane Univ Hosp, Dept Cardiol, Clin Sci, Lund, Sweden.
Lund Univ, Skane Univ Hosp, Dept Cardiol, Clin Sci, Lund, Sweden.
Visa övriga samt affilieringar
2018 (Engelska)Ingår i: BMJ. British Medical Journal, E-ISSN 1756-1833, Vol. 363, artikel-id k4811Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

OBJECTIVES To study circadian rhythm aspects, national holidays, and major sports events as triggers of myocardial infarction.

DESIGN Retrospective observational study using the nationwide coronary care unit registry, SWEDEHEART.

SETTING Sweden.

PARTICIPANTS 283 014 cases of myocardial infarction reported to SWEDEHEART between 1998 and 2013. Symptom onset date was documented for all cases, and time to the nearest minute for 88%.

INTERVENTIONS Myocardial infarctions with symptom onset on Christmas/New Year, Easter, and Midsummer holiday were identified. Similarly, myocardial infarctions that occurred during a FIFA World Cup, UEFA European Championship, and winter and summer Olympic Games were identified. The two weeks before and after a holiday were set as a control period, and for sports events the control period was set to the same time one year before and after the tournament. Circadian and circaseptan analyses were performed with Sunday and 24:00 as the reference day and hour with which all other days and hours were compared. Incidence rate ratios were calculated using a count regression model.

MAIN OUTCOME MEASURES Daily count of myocardial infarction.

RESULTS Christmas and Midsummer holidays were associated with a higher risk of myocardial infarction (incidence rate ratio 1.15, 95% confidence interval 1.12 to 1.19, P<0.001, and 1.12, 1.07 to 1.18, P<0.001, respectively). The highest associated risk was observed for Christmas Eve (1.37, 1.29 to 1.46, P<0.001). No increased risk was observed during Easter holiday or sports events. A circaseptan and circadian variation in the risk of myocardial infarction was observed, with higher risk during early mornings and on Mondays. Results were more pronounced in patients aged over 75 and those with diabetes and a history of coronary artery disease.

CONCLUSIONS In this nationwide real world study covering 16 years of hospital admissions for myocardial infarction with symptom onset documented to the nearest minute, Christmas, and Midsummer holidays were associated with higher risk of myocardial infarction, particularly in older and sicker patients, suggesting a role of external triggers in vulnerable individuals.

Ort, förlag, år, upplaga, sidor
2018. Vol. 363, artikel-id k4811
Nationell ämneskategori
Kardiologi
Identifikatorer
URN: urn:nbn:se:uu:diva-372933DOI: 10.1136/bmj.k4811ISI: 000453691400001PubMedID: 30541902OAI: oai:DiVA.org:uu-372933DiVA, id: diva2:1277433
Forskningsfinansiär
VetenskapsrådetStiftelsen för strategisk forskning (SSF)Knut och Alice Wallenbergs StiftelseHjärt-LungfondenTillgänglig från: 2019-01-10 Skapad: 2019-01-10 Senast uppdaterad: 2019-01-10Bibliografiskt granskad

Open Access i DiVA

Fulltext saknas i DiVA

Övriga länkar

Förlagets fulltextPubMed

Sök vidare i DiVA

Av författaren/redaktören
Lindahl, Bertil
Av organisationen
KardiologiUppsala kliniska forskningscentrum (UCR)
I samma tidskrift
BMJ. British Medical Journal
Kardiologi

Sök vidare utanför DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf