Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Mass spectral study of the skin peptide of brown frog Rana temporaria from Zvenigorod population
Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Kemiska sektionen, Institutionen för fysikalisk och analytisk kemi, Analytisk kemi.
Vise andre og tillknytning
2011 (engelsk)Inngår i: Journal of Analytical Chemistry, ISSN 1061-9348, E-ISSN 1608-3199, Vol. 66, nr 14, s. 1353-1360Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Skin secretions of amphibian are an interesting source of biologically active peptides. The present study provides the profile of the skin secretions of the brown frog Rana temporaria from Zvenigorod population (Russia). Sequencing of the skin secretion components has been carried out on an ion cyclotron resonance instrument with electrospray ionization and two methods of fragmentation activation, collisional activation and electron capture. For sequencing of the peptides containing intermolecular C-terminal disulfide cycle two methods of disulfide bond opening have been used: reduction with subsequent alkylation of the free thiol groups and oxidation with performic acid with the formation of sulfo-acid groups. The peptide profile of Rana temporaria studied by a complex mass spectral method has been compared with the data for the frogs of other European populations of this species. For the first time we have revealed ornithokinin-antagonist of the ornithokinin receptor-in skin secretions of amphibians.

sted, utgiver, år, opplag, sider
2011. Vol. 66, nr 14, s. 1353-1360
Emneord [en]
Rana temporaria, Fourier transformation ion cyclotron resonance, mass spectral sequencing, disulfide-containing peptides, ornithokinin, temporins
HSV kategori
Identifikatorer
URN: urn:nbn:se:uu:diva-167634DOI: 10.1134/S1061934811140152ISI: 000298358800001OAI: oai:DiVA.org:uu-167634DiVA, id: diva2:488983
Tilgjengelig fra: 2012-02-02 Laget: 2012-01-31 Sist oppdatert: 2017-12-08bibliografisk kontrollert

Open Access i DiVA

Fulltekst mangler i DiVA

Andre lenker

Forlagets fulltekst

Søk i DiVA

Av forfatter/redaktør
Artemenko, Konstantin A.
Av organisasjonen
I samme tidsskrift
Journal of Analytical Chemistry

Søk utenfor DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric

doi
urn-nbn
Totalt: 838 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf