Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
The inherited risk of retained placenta: a population based cohort study.
Karolinska Inst, Dept Clin Sci & Educ, Södersjukhuset, Stockholm, Sweden.
Karolinska Inst, Dept Med, Clin Epidemiol Unit, Stockholm, Sweden.
Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Klinisk obstetrik. Karolinska Inst, Dept Med, Clin Epidemiol Unit, Stockholm, Sweden.ORCID-id: 0000-0002-6311-9506
Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Klinisk obstetrik. Karolinska Inst, Dept Med, Clin Epidemiol Unit, Stockholm, Sweden.
2018 (engelsk)Inngår i: British Journal of Obstetrics and Gynecology, ISSN 1470-0328, E-ISSN 1471-0528, Vol. 125, nr 6, s. 737-744Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Objective: To investigate whether retained placenta in the first generation is associated with an increased risk of retained placenta in the second generation.

Design: Population‐based cohort study.

Setting: Sweden.

Population: Using linked generational data from the Swedish Medical Birth Register 1973–2012, we identified 494 000 second‐generation births with information on the birth of the mother (first‐generation index birth). For 292 897 of these births there was information also on the birth of the father.

Methods: Risk of retained placenta in the second generation was calculated as adjusted odds ratios (aOR) by unconditional logistic regression with 95% confidence intervals (95% CI) according to whether retained placenta occurred in a first generation birth or not.

Main outcome: Retained placenta in the second generation.

Results: The risk of retained placenta in a second‐generation birth was increased if retained placenta had occurred at the mother's own birth (aOR 1.66, 95% CI 1.52–1.82), at the birth of one of her siblings (aOR 1.58, 95% CI 1.43–1.76) or both (aOR 2.75, 95% CI 2.18–3.46). The risk was slightly increased if retained placenta had occurred at the birth of the father (aOR 1.23, 95% CI 1.07–1.41). For preterm births in both generations, the risk of retained placenta in the second generation was increased six‐fold if retained placenta had occurred at the mother's birth (OR 6.55, 95% CI 2.68–16.02).

Conclusion: There is an intergenerational recurrence of retained placenta on the maternal and most likely also on the paternal side. The recurrence risk seems strongest in preterm pregnancies.

Tweetable abstract: A population‐based cohort study suggests that there is an intergenerational recurrence of retained placenta.

sted, utgiver, år, opplag, sider
2018. Vol. 125, nr 6, s. 737-744
Emneord [en]
inherited risk, retained placenta
HSV kategori
Forskningsprogram
Obstetrik och gynekologi
Identifikatorer
URN: urn:nbn:se:uu:diva-336792DOI: 10.1111/1471-0528.14828ISI: 000431000400022PubMedID: 28731581OAI: oai:DiVA.org:uu-336792DiVA, id: diva2:1167053
Forskningsfinansiär
Swedish Research Council, 2014-3561Tilgjengelig fra: 2017-12-17 Laget: 2017-12-17 Sist oppdatert: 2018-08-10bibliografisk kontrollert

Open Access i DiVA

Fulltekst mangler i DiVA

Andre lenker

Forlagets fulltekstPubMed

Søk i DiVA

Av forfatter/redaktør
Granfors, MichaelaWikström, Anna-Karin
Av organisasjonen
I samme tidsskrift
British Journal of Obstetrics and Gynecology

Søk utenfor DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric

doi
pubmed
urn-nbn
Totalt: 130 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf