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Long-term adverse effects after retropubic and robot-assisted radical prostatectomy: Nationwide, population-based study
Umea Univ, Dept Surg & Perioperat Sci, Urol & Androl, Umea, Sweden..
Uppsala Univ Hosp, Reg Canc Ctr Uppsala Orebro, Uppsala, Sweden..
Umea Univ, Dept Surg & Perioperat Sci, Urol & Androl, Umea, Sweden..
Umea Univ, Dept Surg & Perioperat Sci, Urol & Androl, Umea, Sweden.;Ryhov Hosp, Dept Urol, Jonkoping, Sweden..
Vise andre og tillknytning
2017 (engelsk)Inngår i: Journal of Surgical Oncology, ISSN 0022-4790, E-ISSN 1096-9098, Vol. 116, nr 4, 500-506 s.Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Background and ObjectivesSurgery for prostate cancer is associated with adverse effects. We studied long-term risk of adverse effects after retropubic (RRP) and robot-assisted radical prostatectomy (RARP). MethodsIn the National Prostate Cancer Register of Sweden, men who had undergone radical prostatectomy (RP) between 2004 and 2014 were identified. Diagnoses and procedures indicating adverse postoperative effects were retrieved from the National Patient Register. Relative risk (RR) of adverse effects after RARP versus RRP was calculated in multivariable analyses adjusting for year of surgery, hospital surgical volume, T stage, Gleason grade, PSA level at diagnosis, patient age, comorbidity, and educational level. ResultsA total of 11212 men underwent RRP and 8500 RARP. Risk of anastomotic stricture was lower after RARP than RRP, RR for diagnoses 0.51 (95%CI=0.42-0.63) and RR for procedures 0.46 (95%CI=0.38-0.55). Risk of inguinal hernia was similar after RARP and RRP but risk of incisional hernia was higher after RARP, RR for diagnoses 1.48 (95%CI=1.01-2.16), and RR for procedures 1.52 (95%CI=1.02-2.26). ConclusionsThe postoperative risk profile for RARP and RRP was quite similar. However, risk of anastomotic stricture was lower and risk of incisional hernia higher after RARP.

sted, utgiver, år, opplag, sider
2017. Vol. 116, nr 4, 500-506 s.
Emneord [en]
adverse effects, cancer of prostate, long-term, prostatectomy
HSV kategori
Identifikatorer
URN: urn:nbn:se:uu:diva-334395DOI: 10.1002/jso.24687ISI: 000408642900010OAI: oai:DiVA.org:uu-334395DiVA: diva2:1170461
Tilgjengelig fra: 2018-01-03 Laget: 2018-01-03 Sist oppdatert: 2018-01-03bibliografisk kontrollert

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