Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Regio- and Stereoselectivity in Glycosyl Disulfide Desulfurization. Generation of S-linked Disaccharides
KTH, Skolan för kemivetenskap (CHE).
2011 (Engelska)Självständigt arbete på avancerad nivå (masterexamen), 20 poäng / 30 hpStudentuppsats (Examensarbete)Alternativ titel
Regio- och stereoselektivitet i desulfurisering av glykosyldisulfider. Framställning av S-länkade disackarider (Svenska)
Abstract [en]

This report describes the synthesis of thiomonosaccharides and the subsequent oxidation to carbohydrate disulfides followed by evaluation of a desulfurization reaction with the aim of developing a facile method for production of S-linked oligosaccharides. The carbohydrate disulfides were synthesized in few steps from commercially available starting materials. Small and simple disulfides were used to evaluate the desulfurization process yielding important information about choice of solvent, catalyst and temperature required for the desulfurization to occur. The optimized conditions were then applied to the carbohydrate disulfides. Results showed that the reactivity of the carbohydrate disulfides depends a lot on the position of the disulfide. One of the carbohydrate disulfides was efficiently desulfurized giving the thioether linked disaccharide, as determined by mass spectrometry. However, more work is needed to develop a general procedure for the desulfurization working on many different carbohydrate disulfides.

Ort, förlag, år, upplaga, sidor
2011. , s. 26
Nyckelord [en]
Synthesis, Carbohydrate, Disulfide, Desulfurization, Selectivity
Nationell ämneskategori
Organisk kemi
Identifikatorer
URN: urn:nbn:se:kth:diva-41495OAI: oai:DiVA.org:kth-41495DiVA, id: diva2:444901
Ämne / kurs
Organisk kemi
Utbildningsprogram
Teknologie masterexamen - Medicinsk teknik
Uppsök
fysik/kemi/matematik
Handledare
Examinatorer
Tillgänglig från: 2011-10-07 Skapad: 2011-09-28 Senast uppdaterad: 2011-11-29Bibliografiskt granskad

Open Access i DiVA

Fulltext saknas i DiVA

Av organisationen
Skolan för kemivetenskap (CHE)
Organisk kemi

Sök vidare utanför DiVA

GoogleGoogle Scholar

urn-nbn

Altmetricpoäng

urn-nbn
Totalt: 51 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf