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  • Nilsing Strid, Emma
    et al.
    Division of Physiotherapy, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden.
    Söderberg, Elsy
    Linköping University, Linköping, Sweden.
    Berterö, Carina
    Linköping University, Linköping, Sweden.
    Öberg, Birgitta
    Linköping University, Linköping, Sweden.
    Primary Healthcare Professionals' Experiences of the Sick Leave Process: A Focus Group Study in Sweden2013In: Journal of occupational rehabilitation, ISSN 1053-0487, E-ISSN 1573-3688, Vol. 23, no 3, p. 450-461Article in journal (Refereed)
    Abstract [en]

    Purpose The aim of this study was to explore primary healthcare (PHC) professionals' experiences of the sick leave process. Methods This is an explorative study using data from four semi-structured focus group discussions with a purposeful sample of PHC professionals in A-stergotland County, Sweden. Content analysis with an inductive approach was used in the analysis. Results Four key themes emerged from the analysis; priority to the sick leave process, handling sickness certifications, collaboration within PHC and with other stakeholders, and work ability assessments. Patients' need for sick leave was handled from each professional group's perspective. Collaboration was considered important, but difficult to achieve and all the competencies available at the PHC centre were not used for work ability assessments. There was insufficient knowledge of patients' work demands and contact with an employer was rare, and the strained relationship with the social insurance officers affected the collaboration. Conclusions This study highlights the challenges physicians and other PHC professionals face when handling the need for sick leave, especially when encountering patients with symptom-based diagnoses, and the influence of non-medical factors. Hindrances to good practice were increased demands, collaboration, and role responsibility. The challenges in the sick leave process concerned both content and consequences related to poor collaboration within PHC and with representatives from various organizations, primarily employers and social insurance officers. Further research on how to develop a professional approach for handling the sick leave process is needed.

  • Planer och budget 20192018Other (Other (popular science, discussion, etc.))
    Abstract [no]

    Det nordiske budsjettet spiller en sentral rolle som et verktøy for styring og prioritering for det nordiske samarbeidet. Store samfunnsmessige utfordringer har også betydning for det nordiske samarbeidet. Det gjelder hvordan vi eksempelvis møter konsekvenser av geopolitiske endringer, migrasjon og klimautfordringer. Økt internasjonal oppmerksomhet omkring nordiske løsninger representerer nye muligheter. Dette krever et dynamisk og fleksibelt samarbeid hvor budsjettet er et viktig redskap for årealisere nye løsninger på nye utfordringene.

  • Tillhagen, Carl-Herman
    The Nordic Museum.
    Folkloristisk fältforskning i 1810-talets Sverige1949In: Fataburen: Nordiska museets och Skansens årsbok, Stockholm: Nordiska museets förlag, 1949, p. 83-90Chapter in book (Other academic)
  • Public defence: 2019-01-25 10:30 H1, Stockholm
    Niazi Ardekani, Mehdi
    KTH, School of Engineering Sciences (SCI), Mechanics.
    Numerical study of transport phenomena in particle suspensions2019Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    Suspensions of solid particles in a viscous liquid are of scientific and technological interest in a wide range of applications. Sediment transport in estuaries, blood flow in the human body, pyroclastic flows from volcanos and pulp fibers in papermaking are among the examples. Often, these particulate flows also include heat transfer among the two phases or the fluid might exhibit a viscoelastic behavior. Predicting these flows and the heat transfer within requires a vast knowledge of how particles are distributed across the domain, how particles affect the flow field and finally how they affect the global behavior of the suspension. The aim of this work is therefore to improve the physical understanding of these flows, including the effect of physical and mechanical properties of the particles and the domain that bounds them.To this purpose, particle-resolved direct numerical simulations (PR-DNS) of spherical/non-spherical particles in different flow regimes and geometries are performed, using an efficient/accurate numerical tool that is developed within this work. The code is based on the Immersed Boundary Method (IBM) for the fluid-solid interactions with lubrication, friction and collision models for the close range particle-particle (particle-wall) interactions, also able to resolve for heat transfer equation in both Newtonian and non-Newtonian fluids.

    Several conclusions are drawn from this study, revealing the importance of the particle's shape and inertia on the global behavior of a suspension, e.g. spheroidal particles tend to cluster while sedimenting. This phenomenon is observed here for both particles with high inertia, sedimenting in a quiescent fluid and inertialess particles (point-like tracer prolates) settling in homogeneous isotropic turbulence. The mechanisms for clustering is indeed different between these two situations, however, it is the shape of the particles that governs these mechanisms, as clustering is not observed for spherical particles. Another striking finding of this work is drag reduction in particulate turbulent channel flow with disk-like spheroidal particles. Again this drag reduction is absent for spherical particles, which instead increase the drag with respect to single-phase turbulence. In particular, we show that inertia at the particle scale induces a non-linear increase of the heat transfer as a function of the volume fraction, unlike the case at vanishing inertia where heat transfer increases linearly within the suspension.

  • Palm, Peter
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Occupational and Environmental Medicine.
    Gupta, Nidhi
    National Research Centre for the Working Environment, Copenhagen, Denmark..
    Forsman, Mikael
    Institute of Environmental Medicine Karolinska Institutet: Stockholm.
    Skotte, Jørgen
    National Research Centre for the Working Environment, Copenhagen, Denmark.
    Nordqvist, Tobias
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Occupational and Environmental Medicine.
    Holtermann, Andreas
    National Research Centre for the Working Environment, Copenhagen, Denmark.
    Exposure to Upper Arm Elevation During Work Compared to Leisure Among 12 Different Occupations Measured with Triaxial Accelerometers.2018In: Annals of work exposures and health, ISSN 2398-7308, Vol. 62, no 6, p. 689-698Article in journal (Refereed)
    Abstract [en]

    Regarding prevention of neck and shoulder pain (NSP), unsupported arm elevation is one factor that should be taken into account when performing work risk assessment. Triaxial accelerometers can be used to measure arm elevation over several days but it is not possible to differentiate between supported and unsupported arm elevation from accelerometers only. Supported arm elevation is more likely to exist during sitting than standing. The aim of the study was to evaluate the use of whole workday measurements of arm elevation with accelerometers to assess potentially harmful work exposure of arm elevation, by comparing arm elevation at work with arm elevation during leisure, in a population with diverse work tasks, and to assess how the exposure parameters were modified when upper arm elevation during sitting time was excluded. The participants, 197 workers belonging to 12 occupational groups with diverse work tasks, wore triaxial accelerometers on the dominant arm, hip, and back for 1-4 days to measure arm elevation and periods of sitting. None of the groups were found to have higher exposure to arm elevation during work compared to leisure. Even though some occupations where known to have work tasks that forced them to work with elevated arms to a large extent. A high proportion of arm elevation derived from sitting time, especially so during leisure. When arm elevation during sitting time was excluded from the analysis, arm elevation was significantly higher at work than during leisure among construction workers, garbage collectors, manufacturing workers, and domestic cleaners. Together this illustrates that it is not suitable to use whole workday measurments of arm elevation with accelerometer as a sole information source when assessing the risk for NSP due to arm elevation. Information on body posture can provide relevant contextual information in exposure assessments when it is known that the potential harmful exposure is performed in standing or walking.

  • Bengtsson, Bengt
    The Nordic Museum.
    Den grillska dopskålen1949In: Fataburen: Nordiska museets och Skansens årsbok, Stockholm: Nordiska museets förlag, 1949, p. 73-82Chapter in book (Other academic)
  • Hålenius, Ulf
    et al.
    Swedish Museum of Natural History, Department of Geology.
    Hatert, Frédéric
    Université de Liège, Belgium..
    Pasero, Marco
    Università di Pisa, Italy..
    Mills, Stuart J.
    Museum Victoria, Melbourne, Australia..
    IMA Commission on New Minerals, Nomenclature and Classification (CNMNC) Newsletter 462018In: European journal of mineralogy, ISSN 0935-1221, E-ISSN 1617-4011, Vol. 30, no 6, p. 181-189Article in journal (Other academic)
  • Kaun, Anne
    et al.
    Södertörn University, School of Culture and Education, Media and Communication Studies.
    Treré, Emiliano
    Cardiff University, Cardiff ,UK.
    Repression, resistance and lifestyle: charting (dis)connection and activism in times of accelerated capitalism2018In: Social Movement Studies, ISSN 1474-2837, E-ISSN 1474-2829Article in journal (Refereed)
    Abstract [en]

    Studying the nexus of media and social movements is a growing subfield in both media and social movement studies. Although there is an increasing number of studies that criticize the overemphasis of the importance of media technologies for social movements, questions of non-use, technology push-back and media refusal as explicit political practice have received comparatively little attention. The article charts a typology of digital disconnection as political practice and site of struggle bringing emerging literatures on disconnection, i.e. forms of media technology non-use to the field of social movement studies and studies of civic engagement. Based on a theoretical matrix combining questions of power, collectivity and temporality, we distinguish between digital disconnection as repression, digital disconnection as resistance and digital disconnection as performance and life-style politics. The article discusses the three types of digital disconnection using current examples of protest and social movements that engage with practices of disconnection.

  • Alkmim, Mansour
    et al.
    Siemens Industry Software.
    Cuenca, Jacques
    Siemens Industry Software, Leuven Belgium.
    de Ryck, Laurent
    Siemens Industry Software, Leuven Belgium.
    Göransson, Peter
    KTH, School of Engineering Sciences (SCI), Aeronautical and Vehicle Engineering, Marcus Wallenberg Laboratory MWL. Centre for ECO2 Vehicle Design.
    Model-based acoustic characterisation of muffler components and extrapolation to inhomogeneous thermal conditions2018Conference paper (Refereed)
  • Mason, David C.
    et al.
    Univ Reading, Dept Geog & Environm Sci, Reading, Berks, England.
    Dance, Sarah L.
    Univ Reading, Dept Meteorol, Reading, Berks, England;Univ Reading, Dept Math & Stat, Reading, Berks, England.
    Vetra-Carvalho, Sanita
    Univ Reading, Dept Meteorol, Reading, Berks, England.
    Cloke, Hannah L.
    Uppsala University, Disciplinary Domain of Science and Technology, Earth Sciences, Department of Earth Sciences, LUVAL. Univ Reading, Dept Geog & Environm Sci, Reading, Berks, England;Univ Reading, Dept Meteorol, Reading, Berks, England.
    Robust algorithm for detecting floodwater in urban areas using synthetic aperture radar images2018In: Journal of Applied Remote Sensing, ISSN 1931-3195, E-ISSN 1931-3195, Vol. 12, no 4, article id 045011Article in journal (Refereed)
    Abstract [en]

    Flooding is a major hazard in both rural and urban areas worldwide, but it is in urban areas that the impacts are most severe. High-resolution synthetic aperture radar (SAR) sensors are able to detect flood extents in urban areas during both day- and night-time. If obtained in near real time, these flood extents can be used for emergency flood relief management or as observations for assimilation into flood forecasting models. A method for detecting flooding in urban areas using near real-time SAR data is developed and extensively tested under a variety of scenarios involving different flood events and different images. The method uses an SAR simulator in conjunction with LiDAR data of the urban area to predict areas of radar shadow and layover in the image caused by buildings and taller vegetation. Of the urban water pixels visible to the SAR, the flood detection accuracy averaged over the test examples is 83%, with a false alarm rate of 9%. The results indicate that flooding can be detected in the urban area to reasonable accuracy but that this accuracy is limited partly by the SAR's poor visibility of the urban ground surface due to shadow and layover. (C) The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License.

  • Cuenca, Jacques
    et al.
    KTH, School of Engineering Sciences (SCI), Aeronautical and Vehicle Engineering. Siemens Industry Software, Leuven Belgium.
    Göransson, Peter
    KTH, School of Engineering Sciences (SCI), Aeronautical and Vehicle Engineering. Centre for ECO2 Vehicle Design.
    de Ryck, Laurent
    Siemens Industry Software, Leuven Belgium.
    Lähivaara, Timo
    University of Eastern Finland.
    Inverse parameter estimation in resonant, coupled fluidstructure interaction problems2018Conference paper (Refereed)
  • Semeniuk, Bradley
    et al.
    KTH, School of Engineering Sciences (SCI), Aeronautical and Vehicle Engineering, Marcus Wallenberg Laboratory MWL.
    Göransson, Peter
    KTH, School of Engineering Sciences (SCI), Centres, VinnExcellence Center for ECO2 Vehicle design. Centre for ECO2 Vehicle Design.
    Dazel, Olivier
    Microstructure based modelling of the thermal and viscous dissipation of a transversely isotropic porous fibrous insulation material.2018Conference paper (Refereed)
  • Hammarsten, Maria
    et al.
    Jönköping University, School of Education and Communication, HLK, Learning Practices inside and outside School (LPS), Sustainability Education Research (SER).
    Askerlund, Per
    Jönköping University, School of Education and Communication, HLK, Learning Practices inside and outside School (LPS), Sustainability Education Research (SER).
    Almers, Ellen
    Jönköping University, School of Education and Communication, HLK, Learning Practices inside and outside School (LPS), Sustainability Education Research (SER).
    Avery, Helen
    Jönköping University, School of Education and Communication, HLK, Learning Practices inside and outside School (LPS), Sustainability Education Research (SER).
    Samuelsson, Tobias
    Jönköping University, School of Education and Communication, HLK, Learning Practices inside and outside School (LPS), Plats, Identitet, Lärande (PIL).
    Barns perspektiv på att vistas i en skogsträdgård2018Conference paper (Refereed)
  • Askerlund, Per
    et al.
    Jönköping University, School of Education and Communication, HLK, Learning Practices inside and outside School (LPS), Sustainability Education Research (SER).
    Almers, Ellen
    Jönköping University, School of Education and Communication, HLK, Learning Practices inside and outside School (LPS), Sustainability Education Research (SER).
    Hur fungerar ekosystemtjänster som verktyg för hållbarhetsarbete på förskolor?2018Conference paper (Refereed)
  • Henriksson, Göran
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Theoretical Astrophysics.
    The acceleration of the Moon and the Universe - the Mass of the Graviton2017In: Advances in Astrophysics, ISSN 2415-6450, Vol. 2, no 3, p. 184-196Article in journal (Refereed)
    Abstract [en]

    To get accurate knowledge about the longitudinal motion of the Moon we must use the oldest preserved interpretable depictions and texts from the ancient cultures. Well documented total solar eclipses from Sumerian cylinder seals, Sumerian, Babylonian, Assyrian, Chinese, Hittite and Greek texts, and depictions on the Swedish rock-carvings from the Bronze Age, have been used in an analysis, performed by the author in 2011, to determine the lunar sidereal secular acceleration. It was based on 33 ancient total or almost total solar eclipses back to 3653 BC. In 2014 and 2016 the margins of error was determined. The new value for the lunar sidereal secular acceleration in longitude = -30.128±0.0035 arcseconds/(century)2 ("/cy2). The lunar secular acceleration, from the Lunar Laser Range (LLR) measurements, -25.856 ±0.003"/cy2, must be corrected for the relativistic effect, -3.604"/cy2, in the Earth-Moon inertial system, to get the lunar sidereal secular acceleration, –29.460 "/cy2, corrected for General Relativity. The difference between this value and the new calibration, -0.668±0.0046"/cy2, corresponds to the cosmological acceleration predicted by Dvali et al. in a Modified Theory of gravity. This value corresponds to a mass of the graviton = 1.306 ±0.009 x 10-56 grams.   If this theory is correct, there is no need for the enigmatic Dark Energy.

  • Murphy, Melissa
    et al.
    University of Oxford.
    Porcelli, Don
    University of Oxford.
    Pogge von Strandmann, Philip
    University College London.
    Hirst, Catherine
    Swedish Museum of Natural History, Department of Geology.
    Kutscher, Liselott
    Swedish Museum of Natural History, Department of Geology.
    Katchinoff, Joachim
    Yale University.
    Mörth, Carl-Magnus
    Stockholm University.
    Maximov, Trofim
    Institute for Biological Problems in the Cryolitic Zone, Yakutsk.
    Andersson, Per
    Swedish Museum of Natural History, Research Division.
    Tracingsilicate weathering processes in the permafrost-dominated Lena River watershedusing lithium isotopes2019In: Geochimica et Cosmochimica Acta, ISSN 0016-7037, E-ISSN 1872-9533, Vol. 245, p. 154-171Article in journal (Refereed)
    Abstract [en]

    Increasing global temperatures are causing widespread changes in the Arctic, including permafrost thawing and altered freshwater inputs and trace metal and carbon fluxes into the ocean and atmosphere. Changes in the permafrost active layer thickness can affect subsurface water flow paths and water-rock interaction times, and hence weathering processes. Riverine lithium isotope ratios (reported as δ7Li) are tracers of silicate weathering that are unaffected by biological uptake, redox, carbonate weathering and primary lithology. Here we use Li isotopes to examine silicate weathering processes in one of the largest Russian Arctic rivers: the Lena River in eastern Siberia. The Lena River watershed is a large multi-lithological catchment, underlain by continuous permafrost. An extensive dataset of dissolved Li isotopic compositions of waters from the Lena River main channel, two main tributaries (the Aldan and Viliui Rivers) and a range of smaller sub tributaries are presented from the post-spring flood/early-summer period at the onset of active layer development and enhanced water-rock interactions. The Lena River main channel (average δ7Lidiss ~19‰) has a slightly lower isotopic composition than the mean global average of 23‰ (Huh

    et al., 1998a). The greatest range of [Li] and δ7Lidiss are observed in catchments draining the south facing slopes of the Verkhoyansk Mountain Range. South-facing slopes in high-latitude, permafrost dominated regions are typically characterised by increased summer insolation and higher daytime temperatures relative to other slope aspects. The increased solar radiation on south-facing catchments promotes repeated freeze-thaw cycles, and contributes to more rapid melting of snow cover, warmer soils, and increased active layer thaw depths. The greater variability in δ7Li and [Li] in the south-facing rivers likely reflect the greater infiltration of melt water and enhanced water rock interactions within the active layer. A similar magnitude of isotopic fractionation is observed between the low-lying regions of the Central Siberian Plateau (and catchments draining into the Viliui River), and catchments draining the Verkhoyansk Mountain Range into the Aldan River. This is in contrast to global rivers in non permafrost terrains that drain high elevations or areas of rapid uplift, where high degrees of physical erosion promote dissolution of freshly exposed primary rock typically yielding low δ7Lidiss, and low lying regions exhibit high riverine δ7Li values resulting from greater water-rock interaction and formation of secondary mineral that fractionates Li isotopes. Overall, the range of Li concentrations and δ7Lidiss observed within the Lena River catchment are comparable to global rivers located in temperate and tropical regions. This suggests that cryogenic weathering features specific to permafrost regions (such as the continual exposure of fresh primary minerals due to seasonal freeze-thaw cycles, frost shattering and salt weathering), and climate (temperature and runoff), are not a dominant control on δ7Li variations. Despite vastly different climatic and weathering regimes, the same range of riverine δ7Li values globally suggests that the same processes govern Li geochemistry – that is, the balance between primary silicate mineral dissolution and the formation (or exchange with) secondary minerals. This has implications for the use of δ7Li as a palaeo weathering tracer for interpreting changes in past weathering regimes.

  • Phoosuwan, Nitikorn
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Caring Sciences.
    Eriksson, Leif
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Caring Sciences.
    Lundberg, Pranee C.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Caring Sciences.
    Statistical Analyses Of The Thai Version Of The Edinburgh Postnatal Depression Scale Among Thai Women During The Antenatal Period In North-Eastern Thailand2017Conference paper (Refereed)
  • Rodin, Sergey
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences. Karolinska Inst, Dept Med Biochem & Biophys, Div Physiol Chem 1, Scheelesvag 2, SE-17177 Stockholm, Sweden.
    Rebellato, Paola
    Biothema AB, Handens Stn Vag 17, S-13640 Handen, Sweden.
    Lundin, Arne
    Biothema AB, Handens Stn Vag 17, S-13640 Handen, Sweden.
    Zubarev, Roman A.
    Karolinska Inst, Dept Med Biochem & Biophys, Div Physiol Chem 1, Scheelesvag 2, SE-17177 Stockholm, Sweden;IM Sechenov First Moscow State Med Univ, Dept Pharmacol & Technol Chem, Moscow, Russia.
    Isotopic resonance at 370 ppm deuterium negatively affects kinetics of luciferin oxidation by luciferase2018In: Scientific Reports, ISSN 2045-2322, E-ISSN 2045-2322, Vol. 8, article id 16249Article in journal (Refereed)
    Abstract [en]

    Since 1930s, it has been known that some biochemical and biological processes exhibit abnormal kinetics at a deuterium concentration in the local environment of 250-600 ppm, which is 2-4 times higher that the normal concentration of 150 ppm D. We sought to test if the kinetics of firefly luciferase oxidizing luciferin, the reaction widely used as a read-out in various biochemical assays, is also affected by an elevated deuterium content. To this end, both luciferase and luciferin substrate solutions were prepared based on water with extra deuterium added to a concentration ranging from 150 ppm and up to 10,000 ppm (1%). Upon mixing the solutions, the luminescence intensity at different times was compared with that of the corresponding control solutions with 150 ppm D. A broad negative resonance was detected (p < 10(-6)), with a approximate to 20% drop in luminescence at 370 ppm D. Given that, on average, about half of hydrogen atoms in proteins are not exchangeable in solution, this value corresponds to approximate to 260 ppm of deuterium in all enzyme's hydrogens, in a very good agreement with the prediction of the Isotopic resonance hypothesis.

  • Lim Falk, Maria
    et al.
    Stockholm University, Faculty of Humanities, Department of Swedish Language and Multilingualism, Scandinavian Languages.
    Wirdenäs, Karolina
    Stockholm University, Faculty of Humanities, Department of Swedish Language and Multilingualism, Scandinavian Languages.
    Skrivande på gymnasiet: Perspektiv på skrivutveckling och textkompetens2018Other (Other academic)
    Abstract [sv]

    Elevernas skrivutveckling når aldrig ett slutmål – nya genrer och nytt innehåll innebär nya utmaningar och fler steg i utvecklingen mot en avancerad skriftspråkskompetens. En utvecklande skrivundervisning behöver göra eleverna förberedda att möta dessa utmaningar, både under gymnasietiden och i kommande studier och yrkesliv.

    Artikeln föreskriver inte en specifik teoribildning eller en utvald skrivpedagogisk inriktning som svar på hur undervisningen kan möta elevernas behov. Den betonar istället att lärare behöver många redskap och göra medvetna val bland dessa i planeringen av en skrivundervisning som ser till alla delar i den skriftspråkliga kompetensen.

    Artikeln resonerar kring de tendenser som genom åren har präglat skrivundervisningen. Hur ska dagens lärare förhålla sig till olika synsätt och inriktningar? En breddad skrivundervisning förespråkas som på olika sätt främjar utvecklingen av elevernas skriftspråkliga kompetens.

  • Public defence: 2019-01-25 13:00 Kollegiesalen, Stockholm
    Gürdür, Didem
    KTH, School of Industrial Engineering and Management (ITM), Machine Design (Dept.), Mechatronics.
    Data and Visual Analytics for Cyber-physical Systems: Current Situation and Strategies for Action2018Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    Today, cyber-physical systems (CPS) exist everywhere in different sizes, with different functionalities and capabilities. CPS often support critical missions that have significant economic and societal importance. They require software systems, communications technologies, sensors/actuators, embedded technologies, and physical systems to work together seamlessly, and they are seen as a driving force behind digital transformation. This dissertation describes the research work carried out to investigate applicability of data and visual analytics for CPS to overcome three main challenges: interoperability, complexity, and sustainability.

    To this end, several case studies are used to effectively implement and test different data and visual analytics solutions to aid stakeholders when they make decisions on interoperability, complexity, and sustainability for CPS. These studies raised questions about issues found to be of importance for the success of data and visual analytics approaches, including accessibility, availability, quality, volume, and variety of data—issues. Moreover, additional studies are used to show the benefits of blending different approaches, such as systems thinking and design thinking, and the current data analytics readiness of the Swedish industry is assessed through a questionnaire completed by more than a hundred respondents. 

    The data and visual analytics are positioned between digitalization and machine intelligence as a research focus. Data and visual analytics is the next step after digitalizing the information by adding analytical capabilities to the data. It is also an important phase before developing machine intelligence applications. Earlier studies clearly show that only a fraction of companies have machine intelligence applications across the enterprise. One important reason behind this is the lack of strong digital capabilities that big data and advanced data analytics technologies could bring. The findings of the work carried out as part of this thesis show the importance of this middle phase—data and visual analytics—for the success of not only the CPS but also these two concepts—digitalization and machine intelligence.

    This thesis concludes by highlighting that currentdata and visual analytics approaches in CPS are closely dependent onthe availability, accessibility, quality, volume, and variety of the data. Notably, the huge amount of industrial data that exists in CPS manufacturers data repositories does not always mean that this data is useful, especially for analytical purposes. To this end, firstly, the CPS industry should concentrate its efforts to collect useful data that will benefit the industry by providing analytical insight intothe environments where CPS is produced and operated. Secondly, the industry should make necessary organizational changes such as considering to employ data scientists, analysts, and business intelligence developers and make data accessible tothese people for further usage. Thirdly, the data management procedures and data analytics roadmaps of companies should be created and shared with other employees, and necessary mechanisms needto be considered to improve and guarantee the quality of the data. Lastly, the variety of data needs to be addressed by the industry. 

    Data and visual analytics provides an opportunity to extract patterns; to evaluate the interoperability, complexity, and sustainability; to create an overview of the current challenge by providing different viewpoints adapted to different stakeholders, focusing on key concerns for the respective stakeholder; to optimize performance, automation, and cooperation of distributed CPS, development environment, and teams; and overall, to improve any of the challenges that are mentioned above by, basically, providing a better understanding.

    To this end, I suggest that the industry discuss the next step after digitalization and address the challenges related to the availability, accessibility, quality, volume, and variety of data by considering user-centric approaches and organizational needs of the future development and manufacturing environments. The CPS industry should plan and act on these challenges as part of its data analytics strategies to expedite the machine intelligence applications of the future.

  • Karademir, Betul
    et al.
    Marmara Univ, Sch Med, Dept Biochem, Genet & Metab Dis Res & Invest Ctr, Istanbul, Turkey.
    Sari, Gulce
    Marmara Univ, Sch Med, Dept Biochem, Genet & Metab Dis Res & Invest Ctr, Istanbul, Turkey;Okan Univ, Fac Engn, Dept Genet & Bioengn, Istanbul, Turkey.
    Jannuzzi, Ayse Tarbin
    Istanbul Univ, Fac Pharm, Dept Pharmaceut Toxicol, Istanbul, Turkey.
    Musunuri, Sravani
    Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Chemistry - BMC, Analytical Chemistry.
    Wicher, Grzegorz
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Immunology, Genetics and Pathology, Neuro-Oncology.
    Grune, Tilman
    German Inst Human Nutr Potsdam Rehbruecke DIfE, Dept Mol Toxicol, D-14558 Nuthetal, Germany;German Ctr Diabet Res DZD, D-85764 Munich, Germany;German Ctr Cardiovasc Res DZHK, D-10117 Berlin, Germany.
    Mi, Jia
    Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Chemistry - BMC, Analytical Chemistry. Binzhou Med Univ, Med & Pharm Res Ctr, Yantai, Peoples R China.
    Hacioglu-Bay, Husniye
    Marmara Univ, Sch Med, Dept Anat, Istanbul, Turkey.
    Forsberg-Nilsson, Karin
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Immunology, Genetics and Pathology, Neuro-Oncology.
    Bergquist, Jonas
    Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Chemistry - BMC, Analytical Chemistry.
    Jung, Tobias
    German Inst Human Nutr Potsdam Rehbruecke DIfE, Dept Mol Toxicol, D-14558 Nuthetal, Germany;German Ctr Diabet Res DZD, D-85764 Munich, Germany;German Ctr Cardiovasc Res DZHK, D-10117 Berlin, Germany.
    Proteomic approach for understanding milder neurotoxicity of Carfilzomib against Bortezomib2018In: Scientific Reports, ISSN 2045-2322, E-ISSN 2045-2322, Vol. 8, article id 16318Article in journal (Refereed)
    Abstract [en]

    The proteasomal system is responsible for the turnover of damaged proteins. Because of its important functions in oncogenesis, inhibiting the proteasomal system is a promising therapeutic approach for cancer treatment. Bortezomib (BTZ) is the first proteasome inhibitor approved by FDA for clinical applications. However neuropathic side effects are dose limiting for BTZ as many other chemotherapeutic agents. Therefore second-generation proteasome inhibitors have been developed including carfilzomib (CFZ). Aim of the present work was investigating the mechanisms of peripheral neuropathy triggered by the proteasome inhibitor BTZ and comparing the pathways affected by BTZ and CFZ, respectively. Neural stem cells, isolated from the cortex of E14 mouse embryos, were treated with BTZ and CFZ and mass spectrometry was used to compare the global protein pool of treated cells. BTZ was shown to cause more severe cytoskeletal damage, which is crucial in neural cell integrity. Excessive protein carbonylation and actin filament destabilization were also detected following BTZ treatment that was lower following CFZ treatment. Our data on cytoskeletal proteins, chaperone system, and protein oxidation may explain the milder neurotoxic effects of CFZ in clinical applications.

  • Lim Falk, Maria
    Stockholm University, Faculty of Humanities, Department of Swedish Language and Multilingualism, Scandinavian Languages.
    Planera för progression2018Other (Other academic)
    Abstract [sv]

    För att planera en undervisning med fokus på språklig progression behöver man utgå från nyanlända elevers förutsättningar och behov så att de får både kognitiva utmaningar och adekvat stöttning. Artikeln introducerar registermodellen som en teoretisk ram för att beskriva språkutveckling, språkanvändning och språklig variation i olika sammanhang.

  • Albaalbaky, Ahmed
    et al.
    Normandie Univ, UNIROUEN, INSA Rouen, CNRS,GPM, F-76800 St Etienne Du Rouvray, France.
    Kvashnin, Yaroslav
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Materials Theory.
    Patte, Renaud
    Normandie Univ, UNIROUEN, INSA Rouen, CNRS,GPM, F-76800 St Etienne Du Rouvray, France.
    Fresard, Raymond
    Normandie Univ, CRISMAT, CNRS, UNICAEN,ENSICAEN, F-14050 Caen, France.
    Ledue, Denis
    Normandie Univ, UNIROUEN, INSA Rouen, CNRS,GPM, F-76800 St Etienne Du Rouvray, France.
    Effects of Ga doping on magnetic and ferroelectric properties of multiferroic delafossite CuCrO2: Ab initio and Monte Carlo approaches2018In: Physical Review B, ISSN 2469-9950, E-ISSN 2469-9969, Vol. 98, no 17, article id 174403Article in journal (Refereed)
    Abstract [en]

    The effects of nonmagnetic impurity doping on magnetic and ferroelectric properties of multiferroic delafossite CuCrO2 are investigated by means of density functional theory calculations and Monte Carlo simulations. Density functional theory calculations show that replacing up to 30% of Cr3+ ions by Ga3+ ones does not significantly affect the remaining Cr-Cr superexchange interactions. Monte Carlo simulations show that CuCr1-xGaxO2 preserves its magnetoelectric properties up to x similar or equal to 0.15 with a spiral ordering, while it becomes disordered at higher fractions. Antiferromagnetic transition shifts towards lower temperatures with increasing x and eventually disappears at x >= 0.2. Our simulations show that Ga3+ doping increases the Curie-Weiss temperature of CuCr1-xGaxO2, which agrees well with experimental observations. Moreover, our results show that the incommensurate ground-state configuration is destabilized by Ga3+ doping under zero applied field associated with an increase of frustration. Finally, coupling between noncollinear magnetic ordering and electric field is reported for x <= 0.15 through simulating P-E hysteresis loops, which leads to ferroelectricity in the extended inverse Dzyaloshinskii-Moriya model.

  • Lim Falk, Maria
    et al.
    Stockholm University, Faculty of Humanities, Department of Swedish Language and Multilingualism, Scandinavian Languages.
    Almström Persson, Gunilla
    Stockholm University, Faculty of Humanities, Department of Swedish Language and Multilingualism, Scandinavian Languages.
    Bygga och värdera kunskap: Texter av vetenskaplig karaktär2018Other (Other academic)
    Abstract [sv]

    Artikeln handlar om vetenskapligt skrivande. Många läroböcker och skrivhandledningar tar upp den vetenskapliga textens disposition, språk och stil. Här ligger i stället fokus på hur övningar i att värdera kunskap och information kan främja ett kritiskt-analytiskt förhållningssätt som en grundläggande förutsättning för att kunna skriva texter av vetenskaplig karaktär.

  • Nikolaidou, Zoe
    et al.
    Södertörn University, School of Culture and Education, Swedish Language.
    Bellander, Theres
    Stockholm Univeristy.
    Health literacy as knowledge construction: Learning about health by expanding objects and crossing boundaries in networked activities2018In: Learning, Culture and Social Interaction, ISSN 2210-6561, E-ISSN 2210-657XArticle, review/survey (Refereed)
    Abstract [en]

    In this paper we examine health literacy as a set of practices that unfold in networked activity systems. Focusing on the literacy practices of pregnant couples and parents of children with heart defect, we show that they participate in multiple activities with the object of constructing knowledge about the child's condition. The contexts for these activities are doctor-patient consultations and the parents' online searching and sharing. The study builds on ethnographic interviews, recorded medical consultations and collection of texts from online forums, blogs and social media. An analysis based on literacy practices and activity theory shows that these activities enable parents' learning, but they can also be restricting as to the mediating tools they provide and the rules that dictate the tools. Additionally, the object of learning about heart defect is not always clearly formulated and stable but it keeps alternating and expanding. As a result, the parents cross boundaries between activities with different mediating tools, rules and communities and thereby different possibilities for learning. We show that doing health literacy is comprised by a set of recontextualised practices of looking for medical and experiential knowledge and it is by a combination of the two that meaningful learning is achieved.

  • Manhica, Hélio
    et al.
    Stockholm University, Faculty of Social Sciences, Centre for Health Equity Studies (CHESS). Röda Korsets Högskola, Stockholm, Sweden.
    Berg, Lisa
    Stockholm University, Faculty of Social Sciences, Centre for Health Equity Studies (CHESS). Stockholm University, Faculty of Social Sciences, Department of Public Health Sciences.
    Almquist, Ylva B.
    Stockholm University, Faculty of Social Sciences, Centre for Health Equity Studies (CHESS). Stockholm University, Faculty of Social Sciences, Department of Public Health Sciences.
    Rostila, Mikael
    Stockholm University, Faculty of Social Sciences, Department of Public Health Sciences.
    Hjern, Anders
    Stockholm University, Faculty of Social Sciences, Centre for Health Equity Studies (CHESS). Stockholm University, Faculty of Social Sciences, Department of Public Health Sciences. Karolinska Institutet, Sweden.
    Labour market participation among young refugees in Sweden and the potential of education: a national cohort study2018In: Journal of Youth Studies, ISSN 1367-6261, E-ISSN 1469-9680Article in journal (Refereed)
    Abstract [en]

    This register-based study examined the importance of education on labour market participation among young refugees in Sweden. The study population consisted of unaccompanied (n = 1606) and accompanied refuges (n = 4142), aged 23–26 years in 2006–2010, after 7 years of residence in Sweden. Native Swedish, aged 24 years (n = 347,255) constituted the comparison population, with intercountry adoptees (n = 6689) as an alternative reference group. Gender-stratified multinomial regression models indicated that unaccompanied and accompanied male and female young refugees had higher risks of being in insecure work force and NEET compared to native Swedes with comparable levels of education. However, young refugees and intercountry adoptees with primary education had similar risks of poor labour market outcomes. The educational differences within each group concerning the risk of being in insecure work force were comparable. With the exception of unaccompanied females, secondary education seemed to be less protective against being in NEET among young refugees compared to native Swedes and intercountry adoptees. We conclude that while young refugees face employment disadvantages, education has the potential of mitigating poor labour market outcomes in this group.

  • Hansson, Katarina
    et al.
    IVL Swedish Environmental Research Institute.
    Andersson, Hanna
    IVL Swedish Environmental Research Institute.
    Ejhed, Heléne
    IVL Swedish Environmental Research Institute.
    Liljeberg, Marcus
    IVL Swedish Environmental Research Institute.
    Olshammar, Mikael
    IVL Swedish Environmental Research Institute.
    Skårman, Tina
    IVL Swedish Environmental Research Institute.
    Sörme, Louise
    SCB Statistics Sweden.
    Dunsö, Olof
    SCB Statistics Sweden.
    Segersson, David
    SMHI Swedish Meteorological and Hydrological Institute.
    Diffuse emissions to air and water2012Report (Other academic)
    Abstract [en]

    The Swedish environmental reporting system has large amounts of information regarding point source discharges. But, point sources represent only a limited part of the total discharges. Therefore contributions from diffuse sources are important to identify in relation to the spread of various substances to the environment. Ex-amples of diffuse sources include road traffic, agriculture, use of solvents, chemi-cals emitted from use-phase of products, and small industries. Here, these and simi-lar diffuse emissions to air are published in the Swedish Pollutant Release and Transfer Register (S-PRTR, with Swedish acronym UTIS). This data is derived from the air and climate reporting made to the Convention on Long-range Trans-boundary Air Pollution (CLRTAP) and UNFCCC. Data at the S-PRTR is listed for several organic pollutants, such as PAHs and heavy metals. Data on diffuse emis-sions to water is currently not provided at the S-PRTR website. Certain diffuse emissions into water are included in the international emission reporting, such as the HELCOM PLC periodical and EEA WISE SoE Emissions.

    The project described herein is based on the development project "Feasibility study for possible publication of diffuse emissions at SPRTR, and is designed to:

     Publish data on emissions from diffuse sources, primarily to water, from selected sectors and substances or substance groups.

     Compare data collected for these diffuse emissions in relation to totals for data reported to E-PRTR.

     Based on the knowledge acquired during this project to propose more regu-lar procedures for collecting data regarding diffuse emissions.

    Substances considered in the project include nutrients (nitrogen and phosphorus), metals (lead, cadmium, copper, mercury, nickel and zinc) and certain organic com-pounds (PAHs, PBDEs, nonylphenols, PCBs, HCHs, DDT, endosulfan, and diox-ins. There is currently no data in certain matrices for these organic pollutants.

    The project has four separate subprojects:

     Diffuse emissions of metals and nutrients to water.Diffuse emissions of certain organic pollutants to water.Diffuse emissions of nonylphenols and nonylphenol ethoxylates from different product groups.Analyses of report-ed data for air and water, and comparison with diffuse emissions.Project 1 covers the following diffuse sources: atmospheric deposition on water, forest land, agriculture, other land, stormwater, local on-site wastewater treatment facilities, industrial facilities and wastewater treatment plants not included in reporting to E-PRTR. Copper is also considered as emission from antifouling boat paint. Subpro-ject 1 findings show that the most significant emission source for nitrogen and phosphorus is agricultural and forests land. Forests dominate as the source of all metals. As well, diffuse emissions of most other metal are significant from agricul-ture, deposition on water, other land and stormwater. Geographically, distribution of emissions shows that stormwater is more significant in the south (Northern Baltic, Southern Baltic, and Skagerrak and Kattegat river basin districts) than in the north (Bothnian Bay and Bothnian Sea river basin districts). This is as expected due to greater traffic volumes in the south. In future, data from water load reporting can be easily recalculated in the geo-database to match publication in the E-PRTR. Coordinating with departments producing water emission statistics is necessary, though.

    Subproject 2 findings show that data for only a few organic pollutants is currently available (such as PAHs, PBDEs, nonylphenols, dioxins, DEHP, PCBs, HCH, DDT, endosulfan and chlorinated paraffins). Data for many of these substances is available only for single or a few diffuse sources (small industries and WWTPs, deposition on water, stormwater and deposition on land). Data for diffuse emis-sions of organic pollutants that is currently available are uncertain and based on few measurements.

    Subproject 3 shows that it is possible to estimate nonylphenols (NPequ) emissions to air, soil and wastewater. The largest source of NPequ to wastewater is from textiles, while smaller amounts are from detergents. The data are uncertain, however, as they are based on emission factors with significant uncertainties.

    Finally,subproject 4 findings show that all diffuse emissions are significant. Dif-fuse emission of nitrogen, phosphorus and metals to water is at least 10 times or more larger compared to point sources, in nearly all cases. Agricultural land domi-nates as a source in the case of phosphorus and nitrogen. Emissions of organic pollutants to water show significant gaps in the data because very few companies report emissions.

    Regarding emissions of organic pollutants and metals to the air, the difference between point sources (E-PRTR) and diffuse emissions based on data from CLRTAP are in most cases not as great as for water. For copper, diffuse emissions to air from brake linings is the largest source of diffuse emission (>90%). And for PAH, diffuse emissions from the energy sector dominates, corresponding to nearly 100% of the total. Emissions of each pollutant (nearly all) is greater to water than to air for point sources, diffuse sources, and the total.

    When comparing emissions from various industries, findings show that forestry industry facilities contribute approximately 90% when it comes to cadmium emis-sions to water from point sources according to E-PRTR (total 440 kg). Still, this is much lower than diffuse emissions as found in Subproject 1, 3,900 kg – indicating diffuse emissions are nearly 9 times greater. The difference for emissions to water is not very large between point sources reported to E-PRTR and those not (in the e-PRTR) – indicating that the point sources under E-PRTR include a large portion of all discharges from point sources to water.

    The quality of data is sufficient to show diffuse emission levels of nutrients and metals at the S-PRTR, reported for the national, river basin district or more refined levels, since this data is based on values reported to the EU and HELCOM. Re-garding organic pollutants to water and nonylphenols from products, the data is more uncertain and is therefore not recommended to be published in the S-PRTR. For emissions to air, our conclusion is that national totals, as reported to the UNPCCC and CLRTAP can be included in the S-PRTR.

  • Schoemaker, Minouk J.
    et al.
    Nichols, Hazel B.
    Wright, Lauren B.
    Brook, Mark N.
    Jones, Michael E.
    O'Brien, Katie M.
    Adami, Hans-Olov
    Baglietto, Laura
    Bernstein, Leslie
    Bertrand, Kimberly A.
    Boutron-Ruault, Marie-Christine
    Braaten, Tonje
    Chen, Yu
    Connor, Avonne E.
    Dorronsoro, Miren
    Dossus, Laure
    Eliassen, A. Heather
    Giles, Graham G.
    Hankinson, Susan E.
    Kaaks, Rudolf
    Key, Timothy J.
    Kirsh, Victoria A.
    Kitahara, Cari M.
    Koh, Woon-Puay
    Larsson, Susanna C.
    Linet, Martha S.
    Ma, Huiyan
    Masala, Giovanna
    Merritt, Melissa A.
    Milne, Roger L.
    Overvad, Kim
    Ozasa, Kotaro
    Palmer, Julie R.
    Peeters, Petra H.
    Riboli, Elio
    Rohan, Thomas E.
    Sadakane, Atsuko
    Sund, Malin
    Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences.
    Tamirni, Rulla M.
    Trichopoulou, Antonia
    Ursin, Giske
    Vatten, Lars
    Visvanathan, Kala
    Weiderpass, Elisabete
    Willett, Walter C.
    Wolk, Alicja
    Yuan, Jian-Min
    Zeleniuch-Jacquotte, Anne
    Sandler, Dale P.
    Swerdlow, Anthony J.
    Association of body mass index and age With subsequent breast cancer risk in premenopausal women2018In: JAMA Oncology, ISSN 2374-2437, E-ISSN 2374-2445, Vol. 4, no 11, article id e181771Article in journal (Refereed)
    Abstract [en]

    IMPORTANCE The association between increasing body mass index (BMI; calculated as wei ght in kilograms divided by height in meters squared) and risk of breast cancer is unique in cancer epidemiology in that a crossover effect exists, with risk reduction before and risk increase after menopause. The inverse association with premenopausal breast cancer risk is poorly characterized but might be important in the understanding of breast cancer causation.

    OBJECTIVE To investigate the association of BMI with premenopausal breast cancer risk, in particular by age at BMI, attained age, risk factors for breast cancer, and tumor characteristics.

    DESIGN, SETTING, AND PARTICIPANTS This multicenter analysis used pooled individual-level data from 758 592 premenopausal women from 19 prospective cohorts to estimate hazard ratios (HRs) of premenopausal breast cancer in association with BMI from ages 18 through 54 years using Cox proportional hazards regression analysis. Median follow-up was 9.3 years (interquartile range, 4.9-13.5 years) per participant, with 13 082 incident cases of breast cancer. Participants were recruited from January 1,1963, through December 31, 2013, and data were analyzed from September 1.2013, through December 31, 2017.

    EXPOSURES Body mass index at ages 18 to 24, 25 to 34,35 to 44, and 45 to 54 years.

    MAIN OUTCOMES AND MEASURES Invasive or in situ premenopausal breast cancer.

    RESULTS Among the 758 592 premenopausal women (median age, 40.6 years; interquartile range, 35.2-45.5 years) included in the analysis, inverse linear associations of BMI with breast cancer risk were found that were stronger for BMI at ages 18 to 24 years (HR per 5 kg/m(2) [5.0-U] difference, 0.77; 95% CI, 0.73-0.80) than for BMI at ages 45 to 54 years (HR per 5.0-U difference, 0.88; 95% CI, 0.86-0.91). The inverse associations were observed even among nonoverweight women. There was a 4.2-fold risk gradient between the highest and lowest BMI categories (BMI >= 35.0 vs <17.0) at ages 18 to 24 years (HR, 0.24; 95% CI, 0.14-0.40). Hazard ratios did not appreciably vary by attained age or between strata of other breast cancer risk factors. Associations were stronger for estrogen receptor-positive and/or progesterone receptor-positive than for hormone receptor-negative breast cancer for BMI at every age group (eg, for BMI at age 18 to 24 years: HR per 5.0-U difference for estrogen receptor-positive and progesterone receptor-positive tumors, 0.76 [95% CI, 0.70-0.81] vs hormone receptor-negative tumors, 0.85 [95% CI: 0.76-0.95]); BMI at ages 25 to 54 years was not consistently associated with triple-negative or hormone receptor-negative breast cancer overall.

    CONCLUSIONS AND RELEVANCE The results of this study suggest that increased adiposity is associated with a reduced risk of premenopausal breast cancer at a greater magnitude than previously shown and across the entire distribution of BMI. The strongest associations of risk were observed for BMI in early adulthood. Understanding the biological mechanisms underlying these associations could have important preventive potential.

  • Skyving, Marie
    et al.
    Transportstyrelsen.
    Forsman, Åsa
    Swedish National Road and Transport Research Institute, Traffic and road users, Traffic Safety and Traffic System.
    Dukic Willstrand, Tania
    Swedish National Road and Transport Research Institute, Traffic and road users, Human Factors in the Transport System.
    Samband mellan sjukdomar och äldre bilförares inblandning i trafikolyckor2018Report (Other academic)
    Abstract [sv]

    Sverige är ett av få länder inom EU som inte har obligatoriska hälsokontroller för förare över en viss ålder. Vår motivering är att man inte kunnat påvisa positiva trafiksäkerhetseffekter av sådana kontroller. Den här studien utreder om personbilsförare som är 65 år eller äldre och som har en sjukdomsdiagnos oftare är inblandade i trafikolyckor jämfört med förare i samma ålder och utan diagnos. 

    Forskningsstudien har sin utgångspunkt i de trafikmedicinska föreskrifterna och de 13 diagnosgrupperna som beskrivs i föreskrifternas olika kapitel. För att undersöka om äldre bilförare med en sjukdomsdiagnos har högre olycksrisk än äldre bilförare utan diagnos har vi matchat en fallpopulation på 13 700 olycksinblandade förare som var 65 år eller äldre med en kontrollgrupp. Kontrollgruppen bestod av 26 500 åldersmatchade personer som skulle uppfylla tre krav: ha giltigt B-körkort (personbil), vara bilägare och inte ha varit inblandade i någon trafikolycka. 

    De register som vi använt oss av är 

     Transportstyrelsens olycksdatabas Strada

     Statistiska centralbyråns befolkningsregister

     Socialstyrelsens patientregister.

    Studien begränsas av ett antal faktorer, till exempel att vi saknar uppgift om exponering i trafik och föreskrivna läkemedel, för att nämna några. Det här innebär bland annat att vi inte kan säga om en t. ex. förhöjd sannolikhet för olycka beror på försämrad körförmåga eller att man kör mer bil och att man därmed är mer exponerad i trafiken. 

  • Östman, Sofi
    Umeå University, Faculty of Arts, Department of historical, philosophical and religious studies, Environmental Archaeology Lab.
    Makrofossilanalys av jordprover från kulturlager inom Sandarnaboplatsen, Raä Göteborg 15:1, Västergötland2018Report (Other academic)
  • Östman, Sofi
    Umeå University, Faculty of Arts, Department of historical, philosophical and religious studies, Environmental Archaeology Lab.
    Makrofossilanalys av sex prover från en boplatsmiljö inom Raä 218, Växjö socken, Småland2018Report (Other academic)
  • Wallin, Jan-Erik
    et al.
    Östman, Sofi
    Umeå University, Faculty of Arts, Department of historical, philosophical and religious studies, Environmental Archaeology Lab.
    Pollenanalys av ett prov från ett vattenhål/kallkälla inom Fjelie socken, Raä 54, Lomma kommun, Skåne2018Report (Other academic)
  • Skårman, Tina
    et al.
    IVL Swedish Environmental Research Institute.
    Hansson, Katarina
    IVL Swedish Environmental Research Institute.
    Mietala, Johanna
    Statistics Sweden.
    Brorström-Lundén, Eva
    IVL Swedish Environmental Research Institute.
    PRTR and synergies with other multilateral agreements, EU legal acts and EEA reportings2014Report (Other academic)
    Abstract [en]

    Swedish Environmental Emissions Data (SMED) has, on behalf of the Swedish Environmental Protection Agency (Swedish EPA) compiled an overview of the multilateral agreements, EU legal acts and EEA reports, which is listed in Table 1, together with identified similarities and differences between these and the UNECE (United Nations Economic Commission for Europe) Protocol on Pollutant Release and Transfer Register, i.e. the PRTR Protocol.

    Relevant general information regarding each agreement has been collected from the Internet and, based on the summarized information, possible synergies with the PRTR protocol have been analyzed.

    The study shows that there are synergies between regulations that are included in the project and the PRTR. Furthermore, the results also show that even though similarities can be identified, each regulation requires different information and is thus unique. In Table 2, identified general synergies are presented, and it can be concluded that the regulations that have most in common with the PRTR protocol are the Minamata Convention and the Industrial Emissions Directive.

  • Gao, Tianle
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience. Chinese Acad Med Sci, Inst Mat Med, Beijing, Peoples R China.
    Ma, Haisha
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Developmental Genetics.
    Xu, Bo
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience.
    Bergman, Jessica
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience.
    Larhammar, Dan
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Pharmacology.
    Lagerström, Malin C.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Developmental Genetics.
    The Neuropeptide Y System Regulates Both Mechanical and Histaminergic Itch2018In: Journal of Investigative Dermatology, ISSN 0022-202X, E-ISSN 1523-1747, Vol. 138, no 11, p. 2405-2411Article in journal (Refereed)
    Abstract [en]

    Itch is a somatosensory modality that serves to alert an organism to harmful elements removable by scratching, such as parasites and chemical irritants. Recently, ablation or silencing of neuropeptide Y (NPY)-expressing spinal interneurons was reported to selectively enhance mechanical itch, whereas chemical itch was unaffected. We examined the effect of activating the NPY/Y-1 receptor system on scratch behavior in mice. We found that intrathecal administration of the Y-1 agonist [Leu(31), Pro(34)]-NPY (LP-NPY) attenuated itch behavior induced by application of 0.07 g von Frey filament in the nape of the neck compared with saline treatment, indicating that activation of the spinal NPY/Y-1 system dampens mechanical itch. However, intrathecal administration of LP-NPY also attenuated chemically induced scratching provoked by intradermal application of histamine or the mast cell degranulator 48/80 (histaminergic itch), and the latter effect could be reversed by administration of the Y-1 antagonist BIBO3304. Intrathecal application of the native nonselective agonist NPY also attenuated histamine or 48/80-induced scratching. Our analyses emphasize the importance of including additional quantitative parameters to characterize the full spectrum of itch behavior and show that the NPY/Y-1 system dampens both mechanically and chemically induced scratching and hence is shared by the two submodalities of itch.

  • Östman, Sofi
    Umeå University, Faculty of Arts, Department of historical, philosophical and religious studies, Environmental Archaeology Lab.
    Makrofossilanalys av fyra prover från kokgropar och nedgrävningar inom Klockarbäcken, Raä Umeå socken 589, Västerbotten2018Report (Other academic)
  • Pincini, D.
    et al.
    UCL, London Ctr Nanotechnol, Gower St, London WC1E 6BT, England;UCL, Dept Phys & Astron, Gower St, London WC1E 6BT, England;Diamond Light Source Ltd, Diamond House,Harwell Sci & Innovat Campus, Didcot OX11 0DE, Oxon, England.
    Fabrizi, F.
    Diamond Light Source Ltd, Diamond House,Harwell Sci & Innovat Campus, Didcot OX11 0DE, Oxon, England.
    Beutier, G.
    Univ Grenoble Alpes, CNRS, Grenoble INP, SIMaP, F-38000 Grenoble, France.
    Nisbet, G.
    Diamond Light Source Ltd, Diamond House,Harwell Sci & Innovat Campus, Didcot OX11 0DE, Oxon, England.
    Elnaggar, H.
    Univ Utrecht, Debye Inst Nanomat Sci, Univ Weg 99, NL-3584 CG Utrecht, Netherlands.
    Dmitrienko, V. E.
    AV Shubnikov Inst Crystallog, FSRC Crystallog & Photon RAS, Moscow 119333, Russia.
    Katsnelson, M. , I
    Kvashnin, Yaroslav
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Materials Theory.
    Lichtenstein, A. , I
    Mazurenko, V. V.
    Ural Fed Univ, Dept Theoret Phys & Appl Math, Mira Str 19, Ekaterinburg 620002, Russia.
    Ovchinnikova, E. N.
    Moscow MV Lomonosov State Univ, Fac Phys, Moscow 119991, Russia.
    Dimitrova, O. , V
    Collins, S. P.
    Diamond Light Source Ltd, Diamond House,Harwell Sci & Innovat Campus, Didcot OX11 0DE, Oxon, England.
    Role of the orbital moment in a series of isostructural weak ferromagnets2018In: Physical Review B, ISSN 2469-9950, E-ISSN 2469-9969, Vol. 98, no 10, article id 104424Article in journal (Refereed)
    Abstract [en]

    The orbital contribution to the magnetic moment of the transition-metal ion in the isostructural weak ferromagnets ACO(3) (A = Mn,Co,Ni) and FeBO3 was investigated by a combination of first-principles calculations, nonresonant x-ray magnetic scattering, and x-ray magnetic circular dichroism. A nontrivial evolution of the orbital moment as a function of the 3d orbitals filling is revealed, with a particularly large value found in the Co member of the family. Here, the coupling between magnetic and lattice degrees of freedom produced by the spin-orbit interaction results in a large single-ion anisotropy and a peculiar magnetic-moment-induced electron cloud distortion, evidenced by the appearance of a subtle scattering amplitude at space-group-forbidden reflections and significant magnetostrictive effects. Our results, which complement a previous investigation on the sign of the Dzyaloshinskii-Moriya interaction across the series, highlight the importance of spin-orbit coupling in the physics of weak ferromagnets and prove the ability of modern first-principles calculations to predict the properties of materials where the Dzyaloshinskii-Moriya interaction is a fundamental ingredient of the magnetic Hamiltonian.

  • Nilsson, Robert
    et al.
    Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Sports medicine.
    Lindberg, Ann-Sofie
    Theos, Apostolos
    Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Sports medicine.
    Ferguson, Richard A
    School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom.
    Malm, Christer B.
    Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Sports medicine.
    Aerobic Variables for Prediction of Alpine Skiing Performance: A Novel Approach2018In: Sports Medicine International Open, ISSN 2367-1890, Vol. 2, no 4, p. 105-112Article in journal (Refereed)
    Abstract [en]

    The aim of this study was to investigate the predictive power of aerobic test results and anthropometric variables on FIS-ranking of junior elite alpine skiers. Results from twenty-three male and female adolescent elite alpine skiers from two seasons were included in the multivariate statistical models. Physical work capacity was determined by V̇O2peak, blood lactate concentration ([HLa]b), and heart rate (HR) during ergometer cycling. Anthropometric variables were body stature, body weight and calculated BMI. No significant correlation between competitive performance and aerobic work capacity or anthropometric data was observed neither in male nor female adolescent skiers. Pre-season physical tests and anthropometric data could therefore not predict end-season FIS-ranking. The best regression (R2) and prediction (Q2) models of FIS slalom (SL) and giant slalom (GS) rank reached R2=0.51 to 0.86, Q2=−0.73 to 0.18, indicating no valid models. This study could not establish V̇O2peak and other included variables as predictors of competitive performance. When combining results from commonly used tests for alpine skiers, and applying multivariate statistical models, investigated tests seems of limited used for athletes, coaches, and ski federations. Performance-specific pre-season tests must be developed and validated for prediction of performance and guidance of exercise training.

  • Appelgren, Ester
    Södertörn University, School of Social Sciences, Journalism.
    Bokrecension: Aske Kammer: Digital journalistik: kort og præcist om medier og kommunikation2018In: Nordicom Information, ISSN 0349-5949, Vol. 40, no 2, p. 124-126Article, book review (Other academic)
  • Sparring, Vibeke
    et al.
    Granström, Emma
    Sachs, Magna Andreen
    Brommels, Mats
    Nyström, Monica E
    Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Epidemiology and Global Health. Department of Learning, Informatics, Management and Ethics, Medical Management Centre, Karolinska Institutet, SE-17177 Stockholm, Sweden.
    One size fits none: a qualitative study investigating nine national quality registries' conditions for use in quality improvement, research and interaction with patients2018In: BMC Health Services Research, ISSN 1472-6963, E-ISSN 1472-6963, Vol. 18, article id 802Article in journal (Refereed)
    Abstract [en]

    Background: Swedish National Quality Registries (NQRs) are observational clinical registries that have long been seen as an underused resource for research and quality improvement (QI) in health care. In recent years, NQRs have also been recognised as an area where patients can be involved, contributing with self-reported experiences and estimations of health effects. This study aimed to investigate what the registry management perceived as barriers and facilitators for the use of NQRs in QI, research, and interaction with patients, and main activities undertaken to enhance their use for these purposes. The aim was further to identify potential differences between various types of NQRs for their use in these areas.

    Methods: In this multiple case study, nine NQRs were purposively selected. Interviews (n = 18) were conducted and analysed iteratively using conventional and directed content analysis.

    Results: A recent national investment initiative enabled more intensive work with development areas previously identified by the NQR management teams. The recent focus on value-based health care and other contemporary national healthcare investments aiming at QI and public benchmarking were perceived as facilitating factors. Having to perform double registrations due to shortcomings in digital systems was perceived as a barrier, as was the lack of authority on behalf of the registry management to request participation in NQRs and QI activities based on registry outcomes. The registry management teams used three strategies to enhance the use of NQRs: ensuring registering of correct and complete data, ensuring updated and understandable information available for patients, clinicians, researchers and others stakeholders, and intensifying cooperation with them. Varied characteristics of the NQRs influenced their use, and the possibility to reach various end-users was connected to the focus area and context of the NQRs.

    Conclusions: The recent national investment initiative contributed to already ongoing work to strengthen the use of NQRs. To further increase the use, the demands of stakeholders and end-users must be in focus, but also an understanding of the NQRs' various characteristics and challenges. The end-users may have in common a need for training in the methodology of registry based research and benchmarking, and how to be more patient-centred.

  • Skårman, Tina
    et al.
    Executive, Forskningsinstitut, IVL Swedish Environmental Research Institute.
    Hansson, Katarina
    Executive, Forskningsinstitut, IVL Swedish Environmental Research Institute.
    Mietala, Johanna
    Statistiska centralbyrån (SCB) .
    Brorström-Lundén, Eva
    Executive, Forskningsinstitut, IVL Swedish Environmental Research Institute.
    PRTR och synergier med andra multilaterala överenskommelser, EU-rättsakter och EEA-rapporteringar2014Report (Other academic)
    Abstract [sv]

    Svenska MiljöEmissionsData (SMED) har på uppdrag av Naturvårdsverket (NV) sammanställt övergripande information om de multilaterala överenskommelser, EU-rättsakter och EEA-rapporteringar som listas i Tabell 1, samt identifierat huruvida det finns beröringspunkter respektive avvikelser mellan dessa och UNECE (United Nations Economic Commission for Europe) -protokollet om "Pollutant Release and Transfer Register", dvs. PRTR-protokollet.

    Relevant övergripande information för respektive reglering har sammanställts från Internet och utifrån dessa sammanställningar har eventuella synergier med PRTR-protokollet analyserats.

    Studien visar att det finns synergier mellan de regleringar som inkluderats i projektet och med PRTR. Samtidigt visar studien att även om man kan identifiera beröringspunkter så efterfrågas inte exakt samma information utan samtliga regleringar är unika. I Tabell 2 redovisas identifierade övergripande synergier och man konstatera att de regleringar som PRTR-protokollet har flest antal beröringspunkter med är Minamatakonventionen och Industriutsläppsdirektivet (IED).

  • Nilsson, Ingeborg
    et al.
    Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Occupational Therapy.
    Luborsky, Mark
    Rosenberg, Lena
    Sandberg, Linda
    Bostrom, Anne-Marie
    Borell, Lena
    Perpetuating harms from isolation among older adults with cognitive impairment: observed discrepancies in homecare service documentation, assessment and approval practices2018In: BMC Health Services Research, ISSN 1472-6963, E-ISSN 1472-6963, Vol. 18, article id 800Article in journal (Refereed)
    Abstract [en]

    Background: Older persons with cognitive impairment (CI) risk social isolation. Strong evidence shows that perceived loneliness, or inadequate social networks, triggers and increases health problems. How homecare systems address social participation remains unknown; anecdotal data suggests there are significant gaps. This study's objective was to identify and describe how the assessors of homecare needs document social participation among persons with CI and how their documentation corresponds with the services actually provided to meet social needs. The research questions were: How and what kinds of social participation needs are documented on need assessment forms? What types of homecare services (with a social focus) are documented and approved? How are specified needs in social participation profiles addressed by a homecare service?

    Methods: Descriptive data from need assessment forms and their attached care plans for all applicants aged 65+ were collected during a 2 month period from a large homecare agency serving a municipality in Sweden. Persons with documented CI (n = 43) in the group were identified. Qualitative data analysis was conducted to examine the research questions.

    Results: Social participation factors were not documented consistently. The relationship between recognition of limitations to social participation and approval of service eligibility was not consistent. Social participation was designated by references to social status, sometimes by social network size, and occasionally by limitations to social participation. The range of approved homecare services (with social focus) covered services such as day care center visits or companionship. Three profiles of social participation were identified: clients with, (a) no participation limitations; (b) potential limitations; and (c) marked limitations.

    Conclusion: Given the known health harms from social isolation and the high risk of isolation among older persons with CI, this novel study's documentation of inadequate and inconsistent information in homecare social need assessments and services is sobering. The findings suggest a pressing need for initiatives to formulate best practices and standards to ensure alignment of care service systems to the health needs of the growing group of aging individuals with CI.

  • Lindblom, Andreas
    The Nordic Museum.
    Anna Regina Khevenhüller till Julita1949In: Fataburen: Nordiska museets och Skansens årsbok, Stockholm: Nordiska museets förlag, 1949, p. 61-72Chapter in book (Other academic)
  • Berlin, Ulla
    The Nordic Museum.
    Ravlundagården och dess gamla miljö1949In: Fataburen: Nordiska museets och Skansens årsbok, Stockholm: Nordiska museets förlag, 1949, p. 35-60Chapter in book (Other academic)
  • Grieg, Sigurd
    Et norsk drikkehorn i Nordiska museet1949In: Fataburen: Nordiska museets och Skansens årsbok, Stockholm: Nordiska museets förlag, 1949, p. 19-34Chapter in book (Other academic)
  • Onn, Gustaf
    Södertörn University, School of Natural Sciences, Technology and Environmental Studies, Tourism Studies.
    Student Involvement as a Tool for Nurturing Business Model Development in Tourism Businesses in the Stockholm Archipelago2018In: Academica Turistica - Tourism and Innovation Journal, ISSN 2335-4194, Vol. 11, no 1, p. 73-86Article in journal (Refereed)
    Abstract [en]

    Tourism consumption in Sweden is booming, but it seems to be at a standstill in the Stockholm archipelago, and most businesses of all kinds in it are small. Therefore, an eu-Interreg-financed educational community engagement project aiming at business model development in the archipelagos of Turku, Åland (both in Finland), and Stockholm was launched, as Finland has a similar situation. In this paper, the foundations of the project, the literature on the issues of being rural and in the archipelago, and business models are reviewed and put in perspective through preliminary empirical results of the project, in while municipality and some business representatives have been interviewed. The rationale is that there is a weak scientific understanding of business models in use in the archipelagos. Methodologically, action research is being used in addition to document studies, with unstructured interviews and observations as the primary empirical methods. The primary results for which the empirical findings put light on the intersection of the abovementioned literature bodies are the impact of infrastructural and access problems due to isolation, as well as indications of a community split between second homes and permanent residents. The lifestyle-entrepreneurship jeopardises the economic well-being but enriches the social well-being of the population. The primary conclusions are that seasonality and second homers provide entrepreneurs with large output markets in season, but small ones in the off-season. The business equation cannot omit place since it is part of the social well-being of the lifestyle-entrepreneurs, which calls for further research into configurational approaches to strategy in an archipelago context.

  • Beckman, Claes
    et al.
    Christian, Braun
    Engblom, Gunnar
    Antenna diversity for mobile telephones1998In: IEEE Antennas and Propagation Society International Symposium. 1998 Digest. Antennas: Gateways to the Global Network. Held in conjunction with: USNC/URSI National Radio Science Meeting (Cat. No.98CH36, Atlanta, GA, 1998, pp. 2220-2223 vol.4. / [ed] IEEE Antennas and Propagation Society, 1998, Vol. 4, p. 2220-2223Conference paper (Refereed)
    Abstract [en]

    There have been several studies made on new diversity antennas for the mobile telephones. The main idea has been to have a built-in (planar) antenna working together with the conventional external. The purpose of this paper is to examine the concept of diversity further and to design two different concepts, one with two external antennas and one with an external antenna combined with an in-built. For evaluation a MATLAB program developed by the Center for Personkommunikation, CPK, in Aalborg, Denmark, is used. Given the radiation pattern from each antenna and the incoming field distribution from the environment, this program calculates the diversity performance of the system assuming that selection combining is used to combine the signals

  • Nerudová, Danuše
    et al.
    Mendel University in Brno.
    Dobranschi, Marian
    Mendel University in Brno.
    Solilová, Veronika
    Mendel University in Brno.
    Schratzenstaller, Margit
    Austrian Institute of Economic Research (WIFO).
    Sustainability-oriented Future EU Funding: A Fuel Tax Surcharge2018Report (Refereed)
    Abstract [en]

    The paper analyses the potential of a surcharge on national fuel taxes as sustainability-oriented own resource to finance the EU budget. Our estimations show that such a surcharge could yield substantial revenues, ranging between € 12.93 billion (for a surcharge of 0.03 €) and 86.2 billion (for a surcharge of 0.2 €) per year. Besides the contribution an EU fuel tax would make to various sustainability-related EU goals and strategies, it would help to address two specific problems inherent in the current EU system of fuel taxation. An EU fuel tax designed as a surcharge on national fuel taxes would decrease the existing tax bias in favour of diesel, as the surcharge would be levied uniformly on gasoline and diesel, which in most EU Member States is taxed at lower rates, alike. Moreover, by increasing national fuel tax rates, the surcharge would – depending on its level – mitigate or even remove the “under-taxation” of fuel in relation to the minimum fuel tax rates stipulated in the EU Energy Tax Directive in a number of Member States, which is caused by the absence of regular inflation adjustment of nominal fuel tax rates.

  • Al-Behadili, Ali
    et al.
    Uhler, Jay P.
    Berglund, Anna-Karin
    Peter, Bradley
    Doimo, Mara
    Umeå University, Faculty of Medicine, Department of Medical Biochemistry and Biophysics.
    Reyes, Aurelio
    Wanrooij, Sjoerd
    Umeå University, Faculty of Medicine, Department of Medical Biochemistry and Biophysics.
    Zeviani, Massimo
    Falkenberg, Maria
    A two-nuclease pathway involving RNase H1 is required for primer removal at human mitochondrial OriL2018In: Nucleic Acids Research, ISSN 0305-1048, E-ISSN 1362-4962, Vol. 46, no 18, p. 9471-9483Article in journal (Refereed)
    Abstract [en]

    The role of Ribonuclease H1 (RNase H1) during primer removal and ligation at the mitochondrial origin of light-strand DNA synthesis (OriL) is a key, yet poorly understood, step in mitochondrial DNA maintenance. Here, we reconstitute the replication cycle of L-strand synthesis in vitro using recombinant mitochondrial proteins and model OriL substrates. The process begins with initiation of DNA replication at OriL and ends with primer removal and ligation. We find that RNase H1 partially removes the primer, leaving behind the last one to three ribonucleotides. These 5′-end ribonucleotides disturb ligation, a conclusion which is supported by analysis of RNase H1-deficient patient cells. A second nuclease is therefore required to remove the last ribonucleotides and we demonstrate that Flap endonuclease 1 (FEN1) can execute this function in vitro. Removal of RNA primers at OriL thus depends on a two-nuclease model, which in addition to RNase H1 requires FEN1 or a FEN1-like activity. These findings define the role of RNase H1 at OriL and help to explain the pathogenic consequences of disease causing mutations in RNase H1.

  • Aaboud, M.
    et al.
    Asimakopoulou, Eleni M.
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Bergeås Kuutmann, Elin
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Bokan, Petar
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Brenner, Richard
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Ekelöf, Tord
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Ellert, Mattias
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Ferrari, Arnaud
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Gradin, P. O. Joakim
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Isacson, Max
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Mårtensson, Mikael
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Öhman, Henrik
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Sales De Bruin, Pedro
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Zur Nedden, M.
    Prompt and non-prompt J/psi and psi(2S) suppression at high transverse momentum in 5.02 TeV Pb+Pb collisions with the ATLAS experiment2018In: European Physical Journal C, ISSN 1434-6044, E-ISSN 1434-6052, Vol. 78, no 9, article id 762Article in journal (Refereed)
    Abstract [en]

    A measurement of J/psi and psi(2S) production is presented. It is based on a data sample from Pb+Pb collisions at root s(NN) = 5.02 TeV and pp collisions at root s = 5.02 TeV recorded by the ATLAS detector at the LHC in 2015, corresponding to an integrated luminosity of 0.42 nb(-1) and 25 pb(-1) in Pb+Pb and pp, respectively. The measurements of per-event yields, nuclear modification factors, and non-prompt fractions are performed in the dimuon decay channel for 9 < p(T)(mu mu) < 40 GeV in dimuon transverse momentum, and -2 < y(mu mu) < 2 in rapidity. Strong suppression is found in Pb+Pb collisions for both prompt and non-prompt J/psi, increasing with event centrality. The suppression of prompt psi(2S) is observed to be stronger than that of J/psi, while the suppression of non-prompt psi(2S) is equal to that of the non-prompt J/psi within uncertainties, consistent with the expectation that both arise from b-quarks propagating through the medium. Despite prompt and non-prompt J/psi arising from different mechanisms, the dependence of their nuclear modification factors on centrality is found to be quite similar.

  • Norström, Elin
    et al.
    Stockholm Univ, Dept Geol Sci, S-10691 Stockholm, Sweden;Stockholm Univ, Bolin Ctr Climate Res, S-10691 Stockholm, Sweden.
    Noren, Gabriel
    Stockholm Univ, Dept Geol Sci, S-10691 Stockholm, Sweden;Stockholm Univ, Bolin Ctr Climate Res, S-10691 Stockholm, Sweden;Univ Cologne, Inst Geol & Mineral, D-50923 Cologne, Germany.
    Smittenberg, Rienk H.
    Stockholm Univ, Dept Geol Sci, S-10691 Stockholm, Sweden;Stockholm Univ, Bolin Ctr Climate Res, S-10691 Stockholm, Sweden.
    Massuanganhe, Elidio A.
    Univ Eduardo Mondlane, Dept Geol, CP 257, Maputo, Mozambique.
    Ekblom, Anneli
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Arts, Department of Archaeology and Ancient History, Archaeology.
    Leaf wax delta D inferring variable medieval hydroclimate and early initiation of Little Ice Age (LIA) dryness in southern Mozambique2018In: Global and Planetary Change, ISSN 0921-8181, E-ISSN 1872-6364, Vol. 170, p. 221-233Article in journal (Refereed)
    Abstract [en]

    A sediment sequence from a coastal, hydrologically isolated lake in southern Mozambique was analysed for leaf wax delta D, n-alkane abundance (ACL) and bulk organic geochemistry (delta C-13, TOC, %N), providing a record of past rainfall variability and savanna dynamics over the last 1500 years. The delta D-wax a rainfall reconstruction reveals a stable hydroclimate between 500-700 CE, while ACL and delta C-13 together with previous pollen data suggest savanna vegetation was characterized by a relatively dense woody cover. Highly variable hydroclimate conditions are inferred by delta D-wax between 800-1350 CE, with repeated centennial scale intervals of extreme dry and wet conditions overlapping the Medieval Climate Anomaly (MCA; 950-1250 CE). Savanna tree cover stayed relatively intact over this phase. After ca 1250 CE, a progressive change towards drier conditions was initiated, leading up to maximum aridity during the AD 1700s, a period associated with the Little Ice age (LIA; 1500-1850 CE). Tree cover was now replaced by a more grass-dominated savanna. The clear antiphase rainfall patterns between Nhaucati and equatorial East African proxy records gives support to the notion that Indian Ocean sea surface temperature (SST) gradients act as modulator of southern African climate on a multi-decadal time scale, possibly forced by long-term El Nino Southern Oscillation (ENSO) variability. We suggest that strong ENSO variability and greater occurrence of La Nina events triggered the generally wet and unstable MCA in southern Africa. From around 1250 CE, a shift towards a predominance of El Nino induced drier conditions in south-east Africa during the LIA. Our study of vegetation and hydroclimate proxies in parallel suggests that savanna tree and shrub cover was relatively resilient to the abrupt shifts in hydroclimate over the MCA, but more sensitive to the long-term progressive drying over the LIA.