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  • Landberg, Ellen
    Konstfack, Institutionen för Konst (K).
    Hur hemslöjdsrörelsen skrev kropp2013Annet (Annet vitenskapelig)
    Abstract [sv]

    I Hur hemslöjdsrörelsen skrev kropp undersöker jag den tidiga hemslöjdsrörelsens syn på estetik och kropp i relation till dess idéer gällande textila tekniker och material. Vilka världen associerades till olika textila uttryck och till dess utövare? Ett exempel är att virkning ansågs vara ett lättjefullt arbete som kunde utföras i liggande ställning. Vad säger den bilden om de som virkade och om det virkade produkterna? Jag är intresserad av hur idéer/teorier gestaltar sig i fysisk form, textilt och i förlängningen kroppsligt. Vem fick vara med i hemslöjdsrörelsen? Vad fick vara med? Och på vilket sätt? Vidare undrar jag hur dessa idéer lever kvar och manifesteras i slöjd och konsthantverksdiskurser idag. Min utgångspunkt är att hemslöjdsrörelsen förenade textil form med positioneringar rörande kön, klass, etnicitet och nation och att själva görandet av slöjd, alltså den textila arbetsprocessen, hade en central plats i formandet av idébygget. Jag prövar här om textilt arbete kopplat till reflektion av kroppsliga upplevelser kan vara en möjlig metod för att utforska det samma. Textilt görande blir en del i ett användande av de metoder kring inhämtning /utveckling /spridning av kunskap som hemslöjdsrörelsen praktiserade. insamling och katalogisering av material efter urval - utställning(försäljning) - föreläsning (kurs/skola) - text

    Genom att gå tillväga på samma sätt som hemslöjdsrörelsen vill jag se hur idéer konstruerades och materialiserades. Det blir också ett sätt att diskutera min egen roll som ytterligare en som konstruerar/omkonstruerar berättelser.

  • Barker, Abigail
    et al.
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Geovetenskapliga sektionen, Institutionen för geovetenskaper, Mineralogi, petrologi och tektonik. Ctr Nat Hazards & Disaster Sci CNDS, Villavagen 16, SE-75236 Uppsala, Sweden.
    Hansteen, Thor H.
    GEOMAR Helmholtz Ctr Ocean Res Kiel, Wischhofstr 1-3, D-24148 Kiel, Germany.
    Nilsson, David
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Geovetenskapliga sektionen, Institutionen för geovetenskaper, Mineralogi, petrologi och tektonik.
    Unravelling the Crustal Architecture of Cape Verde from the Seamount Xenolith Record2019Inngår i: Minerals, ISSN 2075-163X, E-ISSN 2075-163X, Vol. 9, nr 2, artikkel-id 90Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    The Cape Verde oceanic plateau hosts 10 islands and 11 seamounts and provides an extensive suite of alkaline lavas and pyroclastic rocks. The volcanic rocks host a range of crustal and mantle xenoliths. These xenoliths provide a spectrum of lithologies available to interact with magma during transport through the lithospheric mantle and crust. We explore the origin and depth of formation of crustal xenoliths to develop a framework of magma-crust interaction and a model for the crustal architecture beneath the Cape Verde oceanic plateau. The host lavas are phononephelinites to phonolites and the crustal xenoliths are mostly mafic plutonic assemblages with one sedimentary xenolith. REE profiles of clinopyroxene in the host lavas are light rare-earth element (LREE) enriched whereas clinopyoxene from the plutonic xenoliths are LREE depleted. Modelling of REE melt compositions indicates the plutonic xenoliths are derived from mid-ocean ridge basalt (MORB)-type ocean crust. Thermobarometry indicates that clinopyroxene in the host lavas formed at depths of 17 to 46 km, whereas those in the xenoliths formed at 5 to 20 km. This places the depth of origin of the plutonic xenoliths in the oceanic crust. Therefore, the xenoliths trace magma-crust interaction to the MORB oceanic crust and overlying sediments located beneath the Cape Verde oceanic plateau.

  • Lisova, Elena
    et al.
    Mälardalens högskola, Akademin för innovation, design och teknik, Inbyggda system.
    Sljivo, Irfan
    Mälardalens högskola, Akademin för innovation, design och teknik, Inbyggda system.
    Causevic, Aida
    Mälardalens högskola, Akademin för innovation, design och teknik, Inbyggda system.
    Safety and Security Co-Analyses: A Systematic Literature ReviewInngår i: IEEE Systems Journal, ISSN 1932-8184, E-ISSN 1937-9234Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Latest technological trends lead toward systems connected to public networks even in critical domains. Bringing together safety and security work is becoming imperative, as a connected safety-critical system is not safe if it is not secure. The main objective of this study is to investigate the current status of safety and security co-analysis in system engineering by conducting a systematic literature review. The steps of the review are the following: the research questions identification; agreement upon a search string; applying the search string to chosen databases; a selection criterion formulation for the relevant publications filtering; selected papers categorization and analysis. We focused on the early system development stages and identified 33 relevant publications categorized as follows: combined safety and security approaches that consider the mutual influence of safety and security; safety-informed security approaches that consider influence of safety on security; and security-informed safety approaches that consider influence of security on safety. The results showed that a number of identified approaches are driven by needs in fast developing application areas, e.g., automotive, while works focusing on combined analysis are mostly application area independent. Overall, the study shows that safety and security co-analysis is still a developing domain.

  • Disputas: 2019-06-13 09:30 Sal B, Kista
    Farshin, Alireza
    KTH, Skolan för elektroteknik och datavetenskap (EECS), Kommunikationssystem, CoS, Network Systems Laboratory (NS Lab).
    Realizing Low-Latency Internet Services via Low-Level Optimization of NFV Service Chains: Every nanosecond counts!2019Licentiatavhandling, monografi (Annet vitenskapelig)
    Abstract [en]

    By virtue of the recent technological developments in cloud computing, more applications are deployed in a cloud. Among these modern cloud-based applications, some require bounded and predictable low-latency responses. However, the current cloud infrastructure is unsuitable as it cannot satisfy these requirements, due to many limitations in both hardware and software.

    This licentiate thesis describes attempts to reduce the latency of Internet services by carefully studying the currently available infrastructure, optimizing it, and improving its performance. The focus is to optimize the performance of network functions deployed on commodity hardware, known as network function virtualization (NFV). The performance of NFV is one of the major sources of latency for Internet services.

    The first contribution is related to optimizing the software. This project began by investigating the possibility of superoptimizing virtualized network functions(VNFs). This began with a literature review of available superoptimization techniques, then one of the state-of-the-art superoptimization tools was selected to analyze the crucial metrics affecting application performance. The result of our analysis demonstrated that having better cache metrics could potentially improve the performance of all applications.

    The second contribution of this thesis employs the results of the first part by taking a step toward optimizing cache performance of time-critical NFV service chains. By doing so, we reduced the tail latencies of such systems running at 100Gbps. This is an important achievement as it increases the probability of realizing bounded and predictable latency for Internet services.

  • Hasselgren, Kristina
    et al.
    Linkoping Univ, Dept Surg, Linkoping, Sweden;Linkoping Univ, Dept Clin & Expt Med, Linkoping, Sweden.
    Sandstrom, Per
    Linkoping Univ, Dept Surg, Linkoping, Sweden;Linkoping Univ, Dept Clin & Expt Med, Linkoping, Sweden.
    Røsok, Bård Ingvald
    Oslo Univ Hosp, Dept Hepatopancreatobiliary Surg, Oslo, Norway.
    Sparrelid, Ernesto
    Karolinska Inst, Karolinska Univ Hosp, Div Surg, Dept Clin Sci Intervent & Technol, Stockholm, Sweden.
    Lindell, Gert
    Skane Univ Hosp, Dept Surg, Lund, Sweden.
    Nørgaard Larsen, Peter
    Univ Copenhagen, Dept Surg Gastroenterol & Transplantat, Rigshosp, Copenhagen, Denmark.
    Larsson, Anna Lindhoff
    Linkoping Univ, Dept Surg, Linkoping, Sweden;Linkoping Univ, Dept Clin & Expt Med, Linkoping, Sweden.
    Schultz, Nicolai A.
    Univ Copenhagen, Dept Surg Gastroenterol & Transplantat, Rigshosp, Copenhagen, Denmark.
    Bjornbeth, Bjorn Atle
    Oslo Univ Hosp, Dept Hepatopancreatobiliary Surg, Oslo, Norway.
    Isaksson, Bengt
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kirurgiska vetenskaper, Gastrointestinalkirurgi.
    Rizell, Magnus
    Univ Gothenburg, Sahlgrenska Acad, Dept Transplantat & Liver Surg, Gothenburg, Sweden.
    Bjornsson, Bergthor
    Linkoping Univ, Dept Surg, Linkoping, Sweden;Linkoping Univ, Dept Clin & Expt Med, Linkoping, Sweden.
    Future Liver Remnant (FLR) Increase in Patients with Colorectal Liver Metastases Is Highest the First Week After Portal Vein Occlusion: FLR Increase in Patients with CRLM Is Highest the First Week After PVO2019Inngår i: Journal of Gastrointestinal Surgery, ISSN 1091-255X, E-ISSN 1873-4626, Vol. 23, nr 3, s. 556-562Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Background Portal vein occlusion (PVO) is an established method to increase the volume of the future liver remnant (FLR). The main reasons for not proceeding to radical hepatectomy are lack of volume increase and tumor progression due to a wait-time interval of up to 8weeks. The hypothesis was that the increase in FLR volume is not linear and is largest during the first weeks.

    Methods Patients with colorectal liver metastases (CRLM) and standardized future liver remnant (sFLR) <30% treated with PVO were prospectively included. All patients had at least one CT evaluation before radical hepatectomy.

    Results Forty-eight patients were included. During the first week after PVO, the kinetic growth rate (KGR) was 5.4 (±4), compared to 1.5 (±2) between the first and second CT (p<0.05). For patients reaching adequate FLR and therefore treated with radical hepatectomy, the KGR was 7 (±4) the first week, compared to 4.3 (±2) for patients who failed to reach a sufficient volume (p=0.4). During the interval between the first and second CT, the KGR was 2.2 (±2), respectively (±0.1) (p=0.017).

    Discussion The increase in liver volume after PVO is largest during the first week. As KGR decreases over time, it is important to shorten the interval between PVO and the first volume evaluation; this may aid in decision-making and reduce unnecessary waiting time.

  • Conradson, Birgitta
    Nordiska museet.
    Varietéerna - 1890-talets okultur?1991Inngår i: 90tal: visioner och vägval, Stockholm: Nordiska museets förlag, 1991, s. 155-168Kapittel i bok, del av antologi (Annet vitenskapelig)
  • Ekström, Anders
    Stockholmsutställningen 18971991Inngår i: 90tal: visioner och vägval, Stockholm: Nordiska museets förlag, 1991, s. 97-129Kapittel i bok, del av antologi (Annet vitenskapelig)
  • Stalmokaitė, Ignė
    et al.
    Södertörns högskola, Institutionen för naturvetenskap, miljö och teknik, Miljövetenskap.
    Yliskylä-Peuralahti, Johanna
    Centre for Maritime Studies, University of Turku.
    Sustainability Transitions in Baltic Sea Shipping: Exploring the Responses of Firms to Regulatory Changes2019Inngår i: Sustainability, ISSN 2071-1050, E-ISSN 2071-1050, Vol. 11, nr 7, artikkel-id 1916Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    This study investigates how the introduction of more stringent environmental regulation regarding sulphur and nitrogen emission control areas induced shipping companies to react to a new situation and opened up a window of opportunity for build-up of niches for alternative vessel energy sources. By drawing on a multi-level perspective from the socio-technical transition literature, the study provides empirical evidence for how realignments in the environmental regulatory regime alter incumbent actors’ positions and produce varying environmental innovation responses to reduce air-borne pollution from shipping. The study illustrates that the stringency of a regional command-and-control regulation in combination with evolving pressures in the external landscape environment and shipping companies’ task environments are essential components shaping the adoption of environmental innovations. Although incremental innovations seem to dominate in a fossil fuel-based maritime transportation socio-technical system, our results demonstrate the role of regulations and the behaviour of frontrunners in the context of regime fragmentation and sustainability transition processes.

  • Adler, Jeremy
    et al.
    Uppsala universitet, Science for Life Laboratory, SciLifeLab. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinsk cellbiologi.
    Sintorn, Ida-Maria
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Matematisk-datavetenskapliga sektionen, Institutionen för informationsteknologi, Avdelningen för visuell information och interaktion.
    Strand, Robin
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Matematisk-datavetenskapliga sektionen, Institutionen för informationsteknologi, Avdelningen för visuell information och interaktion.
    Parmryd, Ingela
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinsk cellbiologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab. Univ Gothenburg, Sahlgrenska Acad, Inst Biomed, S-40530 Gothenburg, Sweden.
    Conventional analysis of movement on non-flat surfaces like the plasma membrane makes Brownian motion appear anomalous2019Inngår i: COMMUNICATIONS BIOLOGY, ISSN 2399-3642, Vol. 2, artikkel-id 12Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Cells are neither flat nor smooth, which has serious implications for prevailing plasma membrane models and cellular processes like cell signalling, adhesion and molecular clustering. Using probability distributions from diffusion simulations, we demonstrate that 2D and 3D Euclidean distance measurements substantially underestimate diffusion on non-flat surfaces. Intuitively, the shortest within surface distance (SWSD), the geodesic distance, should reduce this problem. The SWSD is accurate for foldable surfaces but, although it outperforms 2D and 3D Euclidean measurements, it still underestimates movement on deformed surfaces. We demonstrate that the reason behind the underestimation is that topographical features themselves can produce both super- and subdiffusion, i.e. the appearance of anomalous diffusion. Differentiating between topography-induced and genuine anomalous diffusion requires characterising the surface by simulating Brownian motion on high-resolution cell surface images and a comparison with the experimental data.

  • Lotfian, Samira
    et al.
    Luleå tekniska universitet, Institutionen för samhällsbyggnad och naturresurser, Mineralteknik och metallurgi.
    Vikström, Tommy
    Boliden Mineral AB, Skelleftehamn, Sweden.
    Lennartsson, Andreas
    Luleå tekniska universitet, Institutionen för samhällsbyggnad och naturresurser, Mineralteknik och metallurgi.
    Björkman, Bo
    Luleå tekniska universitet, Institutionen för samhällsbyggnad och naturresurser, Industriell miljö- och processteknik. Luleå tekniska universitet, Institutionen för samhällsbyggnad och naturresurser, Mineralteknik och metallurgi.
    Ahmed, Hesham
    Central Metallurgical Research and Development Institute (CMRDI), Cairo, Egypt.
    Samuelsson, Caisa
    Luleå tekniska universitet, Institutionen för samhällsbyggnad och naturresurser, Mineralteknik och metallurgi. Luleå tekniska universitet, Institutionen för samhällsbyggnad och naturresurser, Industriell miljö- och processteknik.
    Plastic-containing materials as alternative reductants for base metal production2019Inngår i: Canadian metallurgical quarterly, ISSN 0008-4433, E-ISSN 1879-1395Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Shredder residue materials are produced after the removal of ferrous and non-ferrous fractions from end-of-life electronic equipment. Despite the high plastic content and metal value in the ash, high percentages of these materials are currently sent to landfills. In this study, the potential of utilising shredder residue material and other plastic-containing materials as reducing agents was studied. Plastic-containing materials were co-injected with coal into a zinc-fuming furnace in Boliden-Rönnskär smelter. The data obtained from the trial, such as the data from the chemical analysis of the slag and the steam production, are discussed. The observations indicate that plastic-containing material can replace up to 1 ton h−1 of coal without a significant decrease in the zinc reduction rate.

  • Rentzhog, Torgärd
    Norrlandsfrågan: från 90-tal till 90-tal1991Inngår i: 90tal: visioner och vägval, Stockholm: Nordiska museets förlag, 1991, s. 169-182Kapittel i bok, del av antologi (Annet vitenskapelig)
  • Myrdal, Janken
    Nordiska museet.
    Jordbruksutvecklingens nya riktning1991Inngår i: 90tal: visioner och vägval, Stockholm: Nordiska museets förlag, 1991, s. 211-222Kapittel i bok, del av antologi (Annet vitenskapelig)
  • Gerdle, Björn
    et al.
    Linkoping Univ, Pain & Rehabil Ctr, Dept Med & Hlth Sci, SE-58185 Linkoping, Sweden.
    Åkerblom, Sophia
    Skane Univ Hosp, Dept Pain Rehabil, Lund, Sweden;Lund Univ, Dept Psychol, Lund, Sweden.
    Jansen, Gunilla Brodda
    Danderyd Hosp, Div Rehabil Med, Dept Clin Sci, Stockholm, Sweden.
    Enthoven, Paul
    Linkoping Univ, Pain & Rehabil Ctr, Dept Med & Hlth Sci, SE-58185 Linkoping, Sweden.
    Ernberg, Malin
    Karolinska Inst, Dept Dent Med, Huddinge, Sweden;SCON, Huddinge, Sweden.
    Dong, Huan-Ji
    Linkoping Univ, Pain & Rehabil Ctr, Dept Med & Hlth Sci, SE-58185 Linkoping, Sweden.
    Stålnacke, Britt-Marie
    Umea Univ, Dept Community Med & Rehabil, Rehabil Med, Umea, Sweden.
    Äng, Björn O.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centrum för klinisk forskning Dalarna. Karolinska Inst, Dept Neurobiol Care Sci & Soc, Div Physiotherapy, Huddinge, Sweden;Dalarna Univ, Sch Educ Hlth & Social Studies, Falun, Sweden.
    Boersma, Katja
    Orebro Univ, Sch Law Psychol & Social Work, Orebro, Sweden.
    Who benefits from multimodal rehabilitation - an exploration of pain, psychological distress, and life impacts in over 35,000 chronic pain patients identified in the Swedish Quality Registry for Pain Rehabilitation2019Inngår i: Journal of Pain Research, ISSN 1178-7090, E-ISSN 1178-7090, Vol. 12, s. 891-908Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Background: Chronic pain patients frequently suffer from psychological symptoms. There is no consensus concerning the prevalence of severe anxiety and depressive symptoms and the strength of the associations between pain intensity and psychological distress. Although an important aspect of the clinical picture is understanding how the pain condition impacts life, little is known about the relative importance of pain and psychological symptoms for individual's life impact. The aims of this study were to identify subgroups of pain patients; to analyze if pain, psychological distress, and life impact variables influence subgrouping; and to investigate how patients in the subgroups benefit from treatments. Methods: Background variables, pain aspects (intensity/severity and spreading), psychological distress (depressive and anxiety symptoms), and two life impact variables (pain interference and perceived life control) were obtained from the Swedish Quality Registry for Pain Rehabilitation for chronic pain patients and analyzed mainly using advanced multivariate methods. Results: Based on >35,000 patients, 35%-40% had severe anxiety or depressive symptoms. Severe psychological distress was associated with being born outside Europe (21%-24% vs 6%-8% in the category without psychological distress) and low education level (20.7%-20.8% vs 26%-27% in the category without psychological distress). Dose relationships existed between the two psychological distress variables and pain aspects, but the explained variances were generally low. Pain intensity/severity and the two psychological distress variables were significantly associated (R-2 =0.40-0.48; P>0.001) with the two life impact variables (pain interference and life control). Two subgroups of patients were identified at baseline (subgroup 1: n=15,901 16,119; subgroup 2: n=20,690-20,981) and the subgroup with the worst situation regarding all variables participated less in an MMRP (51% vs 58%, P<0.001) but showed the largest improvements in outcomes. Conclusion: The results emphasize the need to assess both pain and psychological distress and not take for granted that pain involves high psychological stress in the individual case. Not all patients benefit from MMRP. A better matching between common clinical pictures and the content of MMRPs may help improve results. We only partly found support for treatment resistance in patients with psychological distress burden.

  • Rentzhog, Sten
    Nordiska museet.
    Inför 90-talet1991Inngår i: 90tal: visioner och vägval, Stockholm: Nordiska museets förlag, 1991, s. 9-18Kapittel i bok, del av antologi (Annet vitenskapelig)
  • Hult, Jan
    Industrinationens födelse1991Inngår i: 90tal: visioner och vägval, Stockholm: Nordiska museets förlag, 1991, s. 65-84Kapittel i bok, del av antologi (Annet vitenskapelig)
  • Garmy, Pernilla
    Högskolan Kristianstad, Fakulteten för hälsovetenskap, Forskningsmiljön Children's and Young People's Health in Social Context (CYPHiSCO). Högskolan Kristianstad, Forskningsplattformen för Hälsa i samverkan. Högskolan Kristianstad, Fakulteten för hälsovetenskap, Avdelningen för sjuksköterskeutbildningarna och integrerad hälsovetenskap. Lunds universitet.
    Sömn och hälsa: conference proceeding 20192019Konferanseproceedings (Annet vitenskapelig)
  • Stavenow-Hidemark, Elisabet
    Nordiska museet.
    Hur svemnskt var det svenska?1991Inngår i: 90tal: visioner och vägval, Stockholm: Nordiska museets förlag, 1991, s. 44-64Kapittel i bok, del av antologi (Annet vitenskapelig)
  • Sjödin, David
    et al.
    Luleå tekniska universitet, Centre for Management of Innovation and Technology in Process Industry, Promote. Luleå tekniska universitet, Institutionen för ekonomi, teknik och samhälle, Industriell Ekonomi.
    Parida, Vinit
    Luleå tekniska universitet, Institutionen för ekonomi, teknik och samhälle, Innovation och Design. Luleå tekniska universitet, Institutionen för ekonomi, teknik och samhälle, Industriell Ekonomi.
    Cenamor, Javier
    Luleå tekniska universitet, Institutionen för ekonomi, teknik och samhälle, Industriell Ekonomi.
    Digital Platforms to Enable Servitization: How leading manufacturers leverage digitalization to provide advanced services2018Inngår i: Management of Innovation and Technology, ISSN 2001-208X, nr 3, s. 10-11Artikkel i tidsskrift (Annet (populærvitenskap, debatt, mm))
    Abstract [en]

    Swedish manufacturing firms are increasingly adopting pioneering digital technologies and analytics to support advanced service provision in an attempt to achieve sustainable competitive advantages. This article explains how a platform approach to digitalization can help manufacturers achieve both customization and operational efficiency in advanced service provision across global markets.

  • Hellspong, Mats
    Nordiska museet.
    Idrottens födelse1991Inngår i: 90tal: visioner och vägval, Stockholm: Nordiska museets förlag, 1991, s. 238-259Kapittel i bok, del av antologi (Annet vitenskapelig)
  • Disputas: 2019-05-13 10:00 Axel Hamberg salen, Uppsala
    Conrady, Kristina
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Geovetenskapliga sektionen, Institutionen för geovetenskaper, Luft-, vatten och landskapslära.
    Wind Turbine Sound in Cold Climates2019Doktoravhandling, med artikler (Annet vitenskapelig)
    Abstract [en]

    The increase in the number of wind turbines (WTs) in populated areas in cold climates increases the number of people potentially being affected by WT sound. Outdoor sound propagation is strongly dependent on meteorological conditions, however, limitations in the knowledge exist regarding the implications of meteorological conditions in cold climates. Long-term acoustic and meteorological measurements were conducted in the vicinity of two wind farms in northern Sweden, to investigate the effect of snow and low-level wind maxima on WT sound, to analyse the occurrence of amplitude modulation and to evaluate selection methods for WT sound measurements. Different selection methodologies were applied to the acoustical data. The simplest method only includes a minimum rotational frequency of the WTs, while the most comprehensive method additionally includes criteria based on spectral resemblance, temporal variation of the sound level, amplitude modulation and wind speed. The effect of snow on WT sound depends on the snow quality. Snow on trees lowers the sound level by ca. 2 dBA. Low-level wind maxima below hub height reduce the sound level near the surface. Since this effect is increasing with increasing strength of the low-level wind maximum, the WT sound is assumed to be partly trapped above the low-level wind maximum. Amplitude modulation was shown to be dependent on atmospheric stability and was most common for very stable conditions. Moreover, a clear difference between the occurrences of amplitude modulation for the two crosswind sectors was observed. The choice of selection method needs to be taken into account when comparing different studies since it affects the results and conclusions. The studies emphasise to include the effects of individual meteorological conditions of a site in the formulation of guidelines on WT sound.

  • Bjorkman, Annica
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Hälso- och sjukvårdsforskning. Univ Gavle, Fac Hlth & Occupat Studies, Gavle, Sweden.
    Andersson, Kajsa
    Univ Gavle, Fac Hlth & Occupat Studies, Gavle, Sweden.
    Bergström, Jenny
    Univ Gavle, Fac Hlth & Occupat Studies, Gavle, Sweden.
    Salzmann-Erikson, Martin
    Univ Gavle, Fac Hlth & Occupat Studies, Gavle, Sweden.
    Increased Mental Illness and the Challenges This Brings for District Nurses in Primary Care Settings2018Inngår i: Issues in Mental Health Nursing, ISSN 0161-2840, E-ISSN 1096-4673, Vol. 39, nr 12, s. 1023-1030Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Patients with mental illness generally make their initial healthcare contact via a registered nurse. Although studies show that encountering and providing care to care-seekers with mental illness might be a challenge, little research exists regarding Primary Care Nurses' (PCN) view of the challenges they face. The aim of this study was to qualitatively explore PCNs' reflections on encountering care-seekers with mental illness in primary healthcare settings. The results consist of three themes: constantly experiencing patients falling through the cracks, being restricted by lack of knowledge and resources, and establishing a trustful relationship to overcome taboo, shame, and guilt.

  • Williams, Anna
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Historisk-filosofiska fakulteten, Litteraturvetenskapliga institutionen.
    Kvinnorna och den kluvna staden: Röster ur samtidens arbetarlitteratur2019Inngår i: Creating the City: Identity, Memory and Participation. Conference Proceedings / [ed] Pål Brunnström, Ragnhild Claesson, Malmö: Malmö University , 2019, 1, s. 45-54Konferansepaper (Annet vitenskapelig)
  • Sjödin, David
    Luleå tekniska universitet, Centre for Management of Innovation and Technology in Process Industry, Promote. Luleå tekniska universitet, Institutionen för ekonomi, teknik och samhälle, Industriell Ekonomi.
    Hur Företag Kan Tjäna på Digitalisering: Möjligheter, Fallgropar Och Lärdomar2018Annet (Annet (populærvitenskap, debatt, mm))
    Abstract [sv]

    I en tid av digitalisering utmanas företagen att nyttja digitala möjligheter sprungna ur exempelvis det industriella internet of things, big data och artificiell intelligens. Den transformativa kraften i digital teknik möjliggör affärsmodells-innovation och nya sätt att skapa värden för industriföretag där tjänster och ökat kundfokus är centralt. Digitalisering exponerar emellertid företagen för betydande risk och finansiell belastning p.g.a. bristande förståelse för lämpliga affärsmodeller och organisatoriska utmaningar. I den här policysammanfattningen summeras insikter från studier av mer än 40 ledande företag (såväl leverantörer som småföretag och kunder) som engagerat sig i digital affärsmodellsinnovation. De övergripande slutsatserna presenteras i form av tre fällor och sex lärdomar för att dra nytta av digitalisering. Att lyckas med digitalisering är långt mycket mer komplext än att utveckla ny teknik. En lyckad implementering kräver samspel och förändring mellan teknik, organisatoriska processer och människor samt affärsmodeller både inom företaget och externt i ekosystemet.

  • Rydén, Josef
    Nordiska museet.
    Hembygd för framtiden1991Inngår i: 90tal: visioner och vägval, Stockholm: Nordiska museets förlag, 1991, s. 223-237Kapittel i bok, del av antologi (Annet vitenskapelig)
  • Schön, Ebbe
    Nordiska museet.
    Folkets sångmö: Nittiotalisterna och folkkulturen1991Inngår i: 90tal: visioner och vägval, Stockholm: Nordiska museets förlag, 1991, s. 19-43Kapittel i bok, del av antologi (Annet vitenskapelig)
  • Frigoli, Enrico
    et al.
    Univ Bern, Clin Trials Unit, Bern, Switzerland.
    Smits, Pieter
    Maasstad Hosp, Dept Cardiol, Rotterdam, Netherlands.
    Vranckx, Pascal
    Jessa Ziekenhuis, Hartcentrum Hasselt, Dept Cardiol & Crit Care Med, Hasselt, Belgium;Hasselt Univ, Fac Med & Life Sci, Hasselt, Belgium.
    Ozaki, Yokio
    Fujita Hlth Univ, Sch Med, Dept Cardiol, Toyoake, Aichi, Japan.
    Tijssen, Jan
    Univ Amsterdam, Acad Med Ctr, AMC Heartctr, Amsterdam, Netherlands.
    Juni, Peter
    Univ Toronto, St Michaels Hosp, Li Ka Shing Knowledge Inst, Appl Hlth Res Ctr, Toronto, ON, Canada.
    Morice, Marie-Claude
    CERC, Massy, France.
    Onuma, Yoshinobu
    Erasmus MC, Thorax Ctr, Rotterdam, Netherlands.
    Windecker, Stephan
    Bern Univ Hosp, Dept Cardiol, Bern, Switzerland.
    Frenk, Andre
    Bern Univ Hosp, Dept Cardiol, Bern, Switzerland.
    Spaulding, Christian
    Paris Descartes Univ, Hop Europeen Georges Pompidou, AP HP, INSERM,U 970,Sudden Death Expert Ctr,Cardiol Dept, Paris, France.
    Chevalier, Bernard
    Ramsay Gen Sante, Intervent Cardiol Dept, Inst Cardiovasc Paris Sud, Massy, France.
    Barbato, Emanuele
    Cardiovasc Res Ctr Aalst, Aalst, Belgium;Univ Federico II Naples, Dept Adv Biomed Sci, Div Cardiol, Naples, Italy.
    Tonino, Pim
    Catharina Hosp, Dept Cardiol, Eindhoven, Netherlands.
    Hildick-Smith, David
    Brighton & Sussex Univ Hosp NHSTrust, Brighton, E Sussex, England.
    Roffi, Marco
    Geneva Univ Hosp, Div Cardiol, Geneva, Switzerland.
    Kornowski, Ran
    Tel Aviv Univ, Sackler Sch Med, Rabin Med Ctr, Tel Aviv, Israel.
    Schultz, Carl
    Univ Western Australia, Royal Perth Hosp Campus, Dept Cardiol, Perth, WA, Australia.
    Lesiak, Maciej
    Univ Med Sci, Dept Cardiol 1, Poznan, Poland.
    Iniguez, Andres
    Hosp Alvaro Cunqueiro, Vigo, Spain.
    Colombo, Antonio
    IRCCS San Raffaele Sci Inst, Unit Cardiovasc Intervent, Milan, Italy.
    Alasnag, Mirvat
    King Fahad Armed Forces Hosp, Dept Cardiol, Jeddah, Saudi Arabia.
    Mullasari, Ajit
    Madras Med Mission, Chennai, Tamil Nadu, India.
    James, Stefan K
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Kardiologi.
    Stankovic, Goran
    Univ Belgrade, Clin Ctr Serbia, Dept Cardiol, Belgrade, Serbia;Univ Belgrade, Fac Med, Belgrade, Serbia.
    Ong, Paul J. L.
    Tan Tock Seng Hosp, Singapore, Singapore.
    Rodriguez, Alfredo E.
    Otamendi Hosp, Buenos Aires Sch Med, Cardiac Unit, Cardiovasc Res Ctr CECI, Buenos Aires, DF, Argentina.
    Mahfoud, Felix
    Saarland Univ Hosp, Homburg, Germany.
    Bartunek, Jozef
    Bern Univ Hosp, Dept Cardiol, Bern, Switzerland.
    Moschovitis, Aris
    Bern Univ Hosp, Dept Cardiol, Bern, Switzerland.
    Laanmets, Peep
    North Estonia Med Ctr Fdn, Tallinn, Estonia.
    Leonardi, Sergio
    Fdn IRCCS Policlin San Matteo, Pavia, Italy.
    Heg, Dik
    Univ Bern, Clin Trials Unit, Bern, Switzerland.
    Sunnaker, Mikael
    Univ Bern, Clin Trials Unit, Bern, Switzerland.
    Valgimigli, Marco
    Bern Univ Hosp, Dept Cardiol, Bern, Switzerland.
    Design and rationale of the Management of High Bleeding Risk Patients Post Bioresorbable Polymer Coated Stent Implantation With an Abbreviated Versus Standard DAPT Regimen (MASTER DAPT) Study2019Inngår i: American Heart Journal, ISSN 0002-8703, E-ISSN 1097-6744, Vol. 209, s. 97-105Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Background The optimal duration of antiplatelet therapy in high-bleeding risk (HBR) patients with coronary artery disease treated with newer-generation drug-eluting bioresorbable polymer-coated stents remains unclear. Design MASTER DAPT (clinicaltrial.gov NCT03023020) is an investigator-initiated, open-label, multicenter, randomized controlled trial comparing an abbreviated versus a standard duration of antiplatelet therapy after bioresorbable polymer-coated Ultimaster (TANSEI) sirolimus-eluting stent implantation in approximately 4,300 HBR patients recruited from >= 100 interventional cardiology centers globally. After a mandatory 30-day dual-antiplatelet therapy (DAPT) run-in phase, patients are randomized to (a) a single antiplatelet regimen until study completion or up to 5 months in patients with clinically indicated oral anticoagulation (experimental 1-month DAPT group) or (b) continue DAPT for at least 5 months in patients without or 2 in patients with concomitant indication to oral anticoagulation, followed by a single antiplatelet regimen (standard antipkitelet regimen). With a final sample size of 4,300 patients, this study is powered to assess the noninferiority of the abbreviated antiplatelet regimen with respect to the net adverse clinical and major adverse cardiac and cerebral events composite end points and if satisfied for the superiority of abbreviated as compared to standard antiplatelet therapy duration in terms of major or clinically relevant nonmajor bleeding. Study end points will be adjudicated by a blinded Clinical Events Committee. Conclusions The MASTER DAPT study is the first randomized controlled trial aiming at ascertaining the optimal duration of antiplatelet therapy in HBR patients treated with sirolimus-eluting bioresorbable polymer-coated stent implantation.

  • Pérez G., Andres M.
    et al.
    Universidad de los Andes, Colombia.
    Villegas S, Juan S
    Universidad de los Andes, Colombia.
    López, Omar D.
    Universidad de los Andes, Colombia.
    Suarez, Laura
    Universidad de los Andes, Colombia.
    Escobar, Jaime A.
    Universidad de los Andes, Colombia.
    Numerical and Experimental Estimation of the Efficiency of a Quadcopter Rotor Operating at Hover2019Inngår i: Energies, ISSN 1996-1073, E-ISSN 1996-1073, Vol. 12, nr 2, artikkel-id 261Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Globalization has led to an increase in the use of small copters for different activities such as geo-referencing, agricultural fields monitoring, survillance, among others. This is the main reason why there is a strong interest in the performance of small-scale propellers used in unmanned aerial vehicles. The flow developed by rotors is complex and the estimation of its aerodynamic performance is not a trivial process. In addition, viscous effects, when the rotor operates at low Reynolds, affect its performance. In the present paper, two different computational methods, Computational Fluid Dynamics (CFD) and the Unsteady Vortex Lattice Method (UVLM) with a viscous correction, were used to study the performance of an isolated rotor of a quadcopter flying at hover. The Multi Reference Frame model and transition SST κ−ω turbulence model were used in the CFD simulations. The tip vortex core growth was used to account for the viscous effects in the UVLM. The wake structure, pressure coefficient, thrust and torque predictions from both methods are compared. Thrust and torque results from simulations were validated by means of experimental results of a characterization of a single rotor. Finally, figure of merit of the rotor is evaluated showing that UVLM overestimates the efficiency of the rotor; meanwhile, CFD predictions are close to experimental values.

  • Pettersson, Annika
    et al.
    Kristinehamns kommun.
    Liljekvist, Yvonne
    Karlstads universitet, Fakulteten för hälsa, natur- och teknikvetenskap (from 2013), Institutionen för matematik och datavetenskap (from 2013).
    van Bommel, Jorryt
    Karlstads universitet, Fakulteten för hälsa, natur- och teknikvetenskap (from 2013), Institutionen för matematik och datavetenskap (from 2013).
    Studying concept elements as away to trace students’ conceptual understanding2019Inngår i: Nordisk matematikkdidaktikk, NOMAD: [Nordic Studies in Mathematics Education], ISSN 1104-2176, Vol. 24, nr 1, s. 5-26Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    The understanding of mathematical concepts has been described in terms of conceptdefinition and concept image. We suggest an elaboration of these constructs, theconcept element, to find a way to theoretically describe students’ understanding.The concept element construct was tested in a setting with students working withlinear functions at the secondary school level. Our empirical findings reveal tracesof students’ concept elements regarding linear functions. Some concept elementsappeared early in the process while others appeared after a cognitive conflict (e.g.evoked by the task construction and setting). The detailed grid on which concept elementsare defined was a useful tool, yielding new insights into students’ knowledgeand understanding.

  • Stanaway, Jeffrey D.
    et al.
    Edvardsson, David
    Umeå universitet, Medicinska fakulteten, Institutionen för omvårdnad. School of Nursing and Midwifery, La Trobe University, Melbourne, VIC, Australia.
    Murray, Christopher J. L.
    Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 20172018Inngår i: The Lancet, ISSN 0140-6736, E-ISSN 1474-547X, Vol. 392, nr 10159, s. 1923-1994Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Background: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor quantification that offers a useful tool for synthesising evidence on risks and risk–outcome associations. With each annual GBD study, we update the GBD CRA to incorporate improved methods, new risks and risk–outcome pairs, and new data on risk exposure levels and risk–outcome associations.

    Methods: We used the CRA framework developed for previous iterations of GBD to estimate levels and trends in exposure, attributable deaths, and attributable disability-adjusted life-years (DALYs), by age group, sex, year, and location for 84 behavioural, environmental and occupational, and metabolic risks or groups of risks from 1990 to 2017. This study included 476 risk–outcome pairs that met the GBD study criteria for convincing or probable evidence of causation. We extracted relative risk and exposure estimates from 46 749 randomised controlled trials, cohort studies, household surveys, census data, satellite data, and other sources. We used statistical models to pool data, adjust for bias, and incorporate covariates. Using the counterfactual scenario of theoretical minimum risk exposure level (TMREL), we estimated the portion of deaths and DALYs that could be attributed to a given risk. We explored the relationship between development and risk exposure by modelling the relationship between the Socio-demographic Index (SDI) and risk-weighted exposure prevalence and estimated expected levels of exposure and risk-attributable burden by SDI. Finally, we explored temporal changes in risk-attributable DALYs by decomposing those changes into six main component drivers of change as follows: (1) population growth; (2) changes in population age structures; (3) changes in exposure to environmental and occupational risks; (4) changes in exposure to behavioural risks; (5) changes in exposure to metabolic risks; and (6) changes due to all other factors, approximated as the risk-deleted death and DALY rates, where the risk-deleted rate is the rate that would be observed had we reduced the exposure levels to the TMREL for all risk factors included in GBD 2017.

    Findings: In 2017, 34·1 million (95% uncertainty interval [UI] 33·3–35·0) deaths and 1·21 billion (1·14–1·28) DALYs were attributable to GBD risk factors. Globally, 61·0% (59·6–62·4) of deaths and 48·3% (46·3–50·2) of DALYs were attributed to the GBD 2017 risk factors. When ranked by risk-attributable DALYs, high systolic blood pressure (SBP) was the leading risk factor, accounting for 10·4 million (9·39–11·5) deaths and 218 million (198–237) DALYs, followed by smoking (7·10 million [6·83–7·37] deaths and 182 million [173–193] DALYs), high fasting plasma glucose (6·53 million [5·23–8·23] deaths and 171 million [144–201] DALYs), high body-mass index (BMI; 4·72 million [2·99–6·70] deaths and 148 million [98·6–202] DALYs), and short gestation for birthweight (1·43 million [1·36–1·51] deaths and 139 million [131–147] DALYs). In total, risk-attributable DALYs declined by 4·9% (3·3–6·5) between 2007 and 2017. In the absence of demographic changes (ie, population growth and ageing), changes in risk exposure and risk-deleted DALYs would have led to a 23·5% decline in DALYs during that period. Conversely, in the absence of changes in risk exposure and risk-deleted DALYs, demographic changes would have led to an 18·6% increase in DALYs during that period. The ratios of observed risk exposure levels to exposure levels expected based on SDI (O/E ratios) increased globally for unsafe drinking water and household air pollution between 1990 and 2017. This result suggests that development is occurring more rapidly than are changes in the underlying risk structure in a population. Conversely, nearly universal declines in O/E ratios for smoking and alcohol use indicate that, for a given SDI, exposure to these risks is declining. In 2017, the leading Level 4 risk factor for age-standardised DALY rates was high SBP in four super-regions: central Europe, eastern Europe, and central Asia; north Africa and Middle East; south Asia; and southeast Asia, east Asia, and Oceania. The leading risk factor in the high-income super-region was smoking, in Latin America and Caribbean was high BMI, and in sub-Saharan Africa was unsafe sex. O/E ratios for unsafe sex in sub-Saharan Africa were notably high, and those for alcohol use in north Africa and the Middle East were notably low.

    Interpretation: By quantifying levels and trends in exposures to risk factors and the resulting disease burden, this assessment offers insight into where past policy and programme efforts might have been successful and highlights current priorities for public health action. Decreases in behavioural, environmental, and occupational risks have largely offset the effects of population growth and ageing, in relation to trends in absolute burden. Conversely, the combination of increasing metabolic risks and population ageing will probably continue to drive the increasing trends in non-communicable diseases at the global level, which presents both a public health challenge and opportunity. We see considerable spatiotemporal heterogeneity in levels of risk exposure and risk-attributable burden. Although levels of development underlie some of this heterogeneity, O/E ratios show risks for which countries are overperforming or underperforming relative to their level of development. As such, these ratios provide a benchmarking tool to help to focus local decision making. Our findings reinforce the importance of both risk exposure monitoring and epidemiological research to assess causal connections between risks and health outcomes, and they highlight the usefulness of the GBD study in synthesising data to draw comprehensive and robust conclusions that help to inform good policy and strategic health planning.

  • Shi, Xun
    et al.
    Univ Colorado, Dept Phys, Boulder, CO 80309 USA;Univ Colorado, JILA, Boulder, CO 80309 USA;NIST, Boulder, CO 80309 USA.
    You, Wenjing
    Univ Colorado, Dept Phys, Boulder, CO 80309 USA;Univ Colorado, JILA, Boulder, CO 80309 USA;NIST, Boulder, CO 80309 USA.
    Zhang, Yingchao
    Univ Colorado, Dept Phys, Boulder, CO 80309 USA;Univ Colorado, JILA, Boulder, CO 80309 USA;NIST, Boulder, CO 80309 USA.
    Tao, Zhensheng
    Univ Colorado, Dept Phys, Boulder, CO 80309 USA;Univ Colorado, JILA, Boulder, CO 80309 USA;NIST, Boulder, CO 80309 USA.
    Oppeneer, Peter M.
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Fysiska sektionen, Institutionen för fysik och astronomi, Materialteori.
    Wu, Xianxin
    Julius Maximilians Univ Wurzburg, Inst Theoret Phys & Astrophys, D-97074 Wurzburg, Germany.
    Thomale, Ronny
    Julius Maximilians Univ Wurzburg, Inst Theoret Phys & Astrophys, D-97074 Wurzburg, Germany.
    Rossnagel, Kai
    Univ Kiel, Inst Expt & Appl Phys, D-24098 Kiel, Germany;Deutsches Elektronen-Synchrotron DESY, D-22607 Hamburg, Germany;Ruprecht Haensel Laboratory, Kiel University and DESY, D-24098 Kiel and D-22607 Hamburg, Germany.
    Bauer, Michael
    Univ Kiel, Inst Expt & Appl Phys, D-24098 Kiel, Germany.
    Kapteyn, Henry
    Univ Colorado, Dept Phys, Boulder, CO 80309 USA;Univ Colorado, JILA, Boulder, CO 80309 USA;NIST, Boulder, CO 80309 USA.
    Murnane, Margaret
    Univ Colorado, Dept Phys, Boulder, CO 80309 USA;Univ Colorado, JILA, Boulder, CO 80309 USA;NIST, Boulder, CO 80309 USA.
    Ultrafast electron calorimetry uncovers a new long-lived metastable state in 1T-TaSe2 mediated by mode-selective electron-phonon coupling2019Inngår i: Science Advances, E-ISSN 2375-2548, Vol. 5, nr 3, artikkel-id eaav4449Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Quantum materials represent one of the most promising frontiers in the quest for faster, lightweight, energy-efficient technologies. However, their inherent complexity and rich phase landscape make them challenging to understand or manipulate. Here, we present a new ultrafast electron calorimetry technique that can systematically uncover new phases of quantum matter. Using time- and angle-resolved photoemission spectroscopy, we measure the dynamic electron temperature, band structure, and heat capacity. This approach allows us to uncover a new long-lived metastable state in the charge density wave material 1T-TaSe2, which is distinct from all the known equilibrium phases: It is characterized by a substantially reduced effective total heat capacity that is only 30% of the normal value, because of selective electron-phonon coupling to a subset of phonon modes. As a result, less energy is required to melt the charge order and transform the state of the material than under thermal equilibrium conditions.

  • Brue, Thierry
    et al.
    Aix Marseille Univ, Inst Natl Sante & Rech Med INSERM, U1251, MMG, F-13005 Marseille, France;Hop Conception, AP HM, Ctr Reference Malad Rares Hypophyse HYPO, Dept Endocrinol, F-13005 Marseille, France.
    Lindberg, Anders
    Pfizer Hlth AB, Sollentuna, Sweden.
    van der Lely, Aart Jan
    Erasmus Univ MC, Dept Med, Rotterdam, Netherlands.
    Akerblad, Ann Charlotte
    Pfizer Hlth AB, Sollentuna, Sweden.
    Koltowska-Häggström, Maria
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa.
    Gomez, Roy
    Pfizer, European Med Affairs, B-1050 Brussels, Belgium.
    Droste, Michael
    Hey-Hadavi, Judith
    Pfizer Inc, Endocrine Care, New York, NY USA.
    Strasburger, Christian J.
    Campus Charite Mitte, Dept Med, Div Clin Endocrinol, Berlin, Germany.
    Camacho-Hubner, Cecilia
    Pfizer Inc, Endocrine Care, New York, NY USA.
    Diabetes in patients with acromegaly treated with pegvisomant: observations from acrostudy2019Inngår i: Endocrine (Basingstoke), ISSN 1355-008X, E-ISSN 1559-0100, Vol. 63, nr 3, s. 563-572Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    PurposeTo explore the effects of pegvisomant (PEGV) on glucose metabolism in patients with acromegaly within ACROSTUDY, an international, observational, prospective safety surveillance study.MethodsPatients were retrospectively divided into two cohorts, with (DM group) or without diabetes mellitus (no-DM). Parameters of glucose metabolism and IGF-I values were analyzed yearly both cross-sectionally for 4 years (yrs) and longitudinally at 1 and 4-5yrs of PEGV treatment.ResultsAmong 1762 patients, 510 (28.9%) had DM before PEGV start. At cross-sectional analyses, in the DM group mean blood glucose was 140.058.7mg/dl at baseline, 116.4 +/- 44.8mg/dl at year 1 and 120.0 +/- 44.3mg/dl at yr 4. Mean HbA1c was 6.6 +/- 1.2 % at yr 1 vs. 7.0 +/- 1.4 % at baseline. HbA1c was above 6.5% in 61.9% at baseline and ranged from 45.4 to 53.8% at subsequent yearly time points. At the 4-yr longitudinal analysis, in the DM group (n=109), mean blood glucose decreased by 20.2mg/dl at yr 4, mean HbA1c was 7.0 +/- 1.5% at baseline vs. 6.8 +/- 1.4%. Patients achieved IGF-I normalization in 52.1% and 57.4% of cases in the DM and no-DM groups, respectively at 1 year. The mean daily PEGV dose (mg/day) was higher in the DM group (18.2 vs. 15.3) while the absolute change of IGF-I values from baseline was similar in both groups. PEGV was well tolerated in both groups without any unexpected AEs.Conclusions p id=Par4 Patients with DM had a moderate decrease in mean fasting glucose values during PEGV treatment.

  • Ambjörnsson, Ronny
    En skön, ny värld: om Ellen Keys visioner och en senare tids verklighet1991Inngår i: 90tal: visioner och vägval, Stockholm: Nordiska museets förlag, 1991, s. 260-278Kapittel i bok, del av antologi (Annet vitenskapelig)
  • Klingberg, Sofia
    et al.
    Mehlig, Kirsten
    Johansson, Ingegerd
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi. Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Näringsforskning.
    Lindahl, Bernt
    Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Yrkes- och miljömedicin.
    Winkvist, Anna
    Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Näringsforskning. Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
    Lissner, Lauren
    Occupational stress is associated with major long-term weight gain in a Swedish population-based cohort2019Inngår i: International Archives of Occupational and Environmental Health, ISSN 0340-0131, E-ISSN 1432-1246, Vol. 92, nr 4, s. 569-576Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Purpose: Occupational stress and obesity are both increasing in prevalence, but prospective findings relating these conditions are inconsistent. We investigated if baseline as well as prolonged exposure to high job demands and low decision latitude were associated with major weight gain (≥ 10% of baseline weight) in 3872 Swedish women and men examined three times over 20 years in the population-based Västerbotten Intervention Program.

    Methods: Anthropometry was measured and participants completed questionnaires on job strain, diet, and other lifestyle factors. Logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (CI), adjusting for confounders.

    Results: Adjusting for age, baseline low decision latitude was associated with major weight gain over 10- and 20-year OR (95% CI) 1.16 (1.00–1.33) and 1.29 (1.13–1.47), respectively (both sexes combined). After adjustment for diet quality and other confounders, the effect over 20 years remained 1.30 (1.13–1.50). Sex modified the effect of prolonged exposure to high job demands over at least 10 years (interaction p = 0.02), showing that high job demands was a risk factor of major weight gain over 20 years in women [1.54 (1.14–2.07)], but not in men [0.87 (0.63–1.19)]. Neither diet nor other lifestyle factors explained these associations.

    Conclusions: In conclusion, low decision latitude predicted major weight gain in women and men. In women, the results suggest an additional contribution to major weight gain from high job demands.

  • Sopher, Daniel
    et al.
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Geovetenskapliga sektionen, Institutionen för geovetenskaper, Geofysik.
    Juhlin, Christopher
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Geovetenskapliga sektionen, Institutionen för geovetenskaper, Geofysik.
    Levendal, Tegan
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Geovetenskapliga sektionen, Institutionen för geovetenskaper.
    Erlstrom, Mikael
    Geol Survey Sweden SGU, Kiliansgatan 10, S-22350 Lund, Sweden;Lund Univ, Dept Geol, Solvegatan 12, S-22362 Lund, Sweden.
    Nilsson, Karl
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Geovetenskapliga sektionen, Institutionen för geovetenskaper.
    Da Silva Soares, José Pedro
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Geovetenskapliga sektionen, Institutionen för geovetenskaper.
    Evaluation of the subsurface compressed air energy storage (CAES) potential on Gotland, Sweden2019Inngår i: Environmental Earth Sciences, ISSN 1866-6280, E-ISSN 1866-6299, Vol. 78, nr 6, artikkel-id 197Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Wind energy is an important field of development for the island of Gotland, Sweden, especially since the island has set targets to generate 100% of its energy from renewable sources by 2025. Due to the variability of wind conditions, energy storage will be an important technology to facilitate the continued development of wind energy on Gotland and ensure a stable and secure supply of electricity. In this study, the feasibility of utilizing the Middle Cambrian Faludden sandstone reservoir on Gotland for Compressed Air Energy Storage (CAES) is assessed. Firstly, a characterization of the sandstone beneath Gotland is presented, which includes detailed maps of reservoir thickness and top reservoir structure. Analysis of this information shows that the properties of the Faludden sandstone and associated cap rock appear favorable for the application of CAES. Seven structural closures are identified below the eastern and southern parts of Gotland, which could potentially be utilized for CAES. Scoping estimates of the energy storage capacity and flow rate for these closures within the Faludden sandstone show that industrial scale CAES could be possible on Gotland.

  • Melin, Roger
    Högskolan Dalarna, Akademin Humaniora och medier, Filosofi.
    Technology and the Existential Element in Sport2018Inngår i: Idrottsforum.org/Nordic sport science forum, ISSN 1652-7224, artikkel-id 2018-12-06Artikkel i tidsskrift (Annet vitenskapelig)
  • Widén, Joakim
    et al.
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Tekniska sektionen, Institutionen för teknikvetenskaper.
    Munkhammar, Joakim
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Tekniska sektionen, Institutionen för teknikvetenskaper.
    Solar Radiation Theory2019 (oppl. 1)Bok (Annet vitenskapelig)
    Abstract [en]

    One of the challenges in solar engineering is that the availability of the solar resource varies with time and location. An important engineering task is to design solar energy systems that are able to collect as much solar radiation as possible under these constraints. This book introduces the basic properties of solar radiation that are required to understand how the solar resource can be converted into useful heat and electricity, and what the limitations are. It also shows how solar radiation on planar surfaces can be modeled mathematically. This is useful when optimizing the orientation of collecting surfaces and predicting the performance of different system designs. The book builds upon lecture notes from solar engineering courses at Uppsala University, carefully edited to suit a wider scientific and engineering audience. The two authors have, together, more than two decades' experience of teaching, research and development in the field of solar irradiance modeling.

  • Egnell, Susanne
    et al.
    Villman, Emma
    Obstbaum, Yaira
    Cannabis policy and legislation in the Nordic countries: A report on the control of cannabis use and possession in the Nordic legalsystems2019Rapport (Annet vitenskapelig)
    Abstract [en]

    How is cannabis use controlled in the legal systems in the Nordic countries? How do the Nordic legal systems see cannabis as a drug, and how does this affect the cannabis user? The Nordic Welfare Centre´s new report Cannabis policy and legislation in the Nordic countries looks at the similarities and differences in legislation and the ways in which the law is enacted in legal practice, police work, and other arenas.

    After alcohol, cannabis is the second most common intoxicant in the Nordics and cannabis use is increasing among young adults in most Nordic countries. It is therefore not insignificant how society views cannabis use: is it a social problem, a health problem, or a problem of law and order? The answer matters a great deal to the user. Increasing use will put pressure on the societal responses although the majority of cannabis users are not problem users in need of treatment.

  • Durig, Wiebke
    et al.
    Tröger, Rikard
    Andersson, Patrik L.
    Umeå universitet, Teknisk-naturvetenskapliga fakulteten, Kemiska institutionen.
    Rybacka, Aleksandra
    Umeå universitet, Teknisk-naturvetenskapliga fakulteten, Kemiska institutionen.
    Fischer, Stellan
    Wiberg, Karin
    Ahrens, Lutz
    Development of a suspect screening prioritization tool for organic compounds in water and biota2019Inngår i: Chemosphere, ISSN 0045-6535, E-ISSN 1879-1298, Vol. 222, s. 904-912Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    A customizable in silico tool (SusTool) for generating high resolution mass spectrometry (HRMS) suspect screening lists, specifically designed for the detection of hazardous organic compounds in various environmental compartments, was created. A database consisting of similar to 32 000 environmentally relevant organic compounds was constructed, including data on their physicochemical properties, environmental fate characteristics, and endocrine disruption potential, along with emissions and quantity indices. Welldefined customized suspect lists were generated by systematic ranking using a scoring and weighting procedure. For demonstration purposes, three suspect screening lists were created, one for water (SLWater) and two for biota covering less (SLBiota Kow<5 ) or more hydrophobic chemicals (SLBiota Kow>3). Scrutiny of overlaps between compounds within these lists and the SusDat database (20 suspect lists comprising similar to 58 000 compounds compiled by the Norman network) showed that approximately half of the compounds in the three suspect lists were also listed in one of the SusDat database lists. This indicates that SusTool is able to include highly relevant emerging pollutants, but also captures other compounds of potential concern that have been less well studied or not yet investigated. Overall, our in silico prioritization approach enables systematic creation of suspect screening lists and provides new opportunities for suspect screening for environmentally relevant compounds. 

  • Cavanagh, Jorunn Pauline
    et al.
    Pain, Maria
    Askarian, Fatemeh
    Bruun, Jack-Ansgar
    Urbarova, Ilona
    Wai, Sun Nyunt
    Umeå universitet, Medicinska fakulteten, Institutionen för molekylärbiologi (Medicinska fakulteten).
    Schrnidt, Frank
    Johannessen, Mona
    Comparative exoproteome profiling of an invasive and a commensal Staphylococcus haemolyticus isolate2019Inngår i: Journal of Proteomics, ISSN 1874-3919, E-ISSN 1876-7737, Vol. 197, s. 106-114Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Staphylococcus haemolyticus is a skin commensal emerging as an opportunistic pathogen. Nosocomial isolates of S. haemolyticus are the most antibiotic resistant members of the coagulase negative staphylococci (CoNS), but information about other S. haemolyticus virulence factors is scarce. Bacterial membrane vesicles (MVs) are one mediator of virulence by enabling secretion and long distance delivery of bacterial effector molecules while protecting the cargo from proteolytic degradation from the environment. We wanted to determine if the MV protein cargo of S. haemolyticus is strain specific and enriched in certain MV associated proteins compared to the totalsecretome.

    The present study shows that both clinical and commensal S. haemolyticus isolates produce membrane vesicles. The MV cargo of both strains was enriched in proteins involved in adhesion and acquisition of iron. The MV cargo of the clinical strain was further enriched in antimicrobial resistance proteins.

    Data are available via ProteomeXchange with identifier PXD010389.

    Biological significance: Clinical isolates of Staphylococcus haemolyticus are usually multidrug resistant, their main virulence factor is formation of biofilms, both factors leading to infections that are difficult to treat. We show that both clinical and commensal S. haemolyticusisolates produce membrane vesicles. Identification of staphylococcal membrane vesicles can potentially be used in novel approaches to combat staphylococcal infections, such as development of vaccines.

  • Carstam, Louise
    et al.
    Smits, Anja
    Milos, Peter
    Corell, Alba
    Henriksson, Roger
    Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper, Onkologi.
    Bartek, Jiri, Jr.
    Jakola, Asgeir Store
    Neurosurgical patterns of care for diffuse low-grade gliomas in Sweden between 2005 and 20152019Inngår i: Neuro-Oncology Practice, ISSN 2054-2577, Vol. 6, nr 2, s. 124-133Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Background: In the last decade, increasing evidence has evolved for early and maximal safe resection of diffuse low-grade gliomas (LGGs) regarding survival. However, changes in clinical practice are known to occur slowly and we do not know if the scientific evidence has yet resulted in changes in neurosurgical patterns of care.

    Methods: The Swedish Brain Tumor Registry was used to identify all patients with a first-time histopathological diagnosis of LGG between 2005 and 2015. For analysis of surgical treatment patterns, we subdivided assessed time periods into 2005-2008, 2009-2012, and 2013-2015. Population-based data on patient and disease characteristics, surgical management, and outcomes were extracted.

    Results: A total of 548 patients with diffuse World Health Organization grade II gliomas were identified: 142 diagnosed during 2005-2008, 244 during 2009-2012, and 162 during 2013-2015. Resection as opposed to biopsy was performed in 64.3% during 2005-2008, 74.2% during 2009-2012, and 74.1% during 2013-2015 (P = .08). There was no difference among the 3 periods regarding overall survival (P= .11). However, post hoc analysis of data from the 4 (out of 6) centers that covered all 3 time periods demonstrated a resection rate of 64.3% during 2005-2008, 77.4% during 2009-2012, and 75.4% during 2013-2015 (P = .02) and longer survival of patients diagnosed 2009 and onward (P = .04).

    Conclusion: In this nationwide, population-based study we observed a shift over time in favor of LGG resection. Further, a positive correlation between the more active surgical strategy and longer survival is shown, although no causality can be claimed because of possible confounding factors.

  • Garnert, Jan
    Nordiska museet.
    90-talsperspektiv på elektrifiering och trefasteknik1991Inngår i: 90tal: visioner och vägval, Stockholm: Nordiska museets förlag, 1991, s. 85-96Kapittel i bok, del av antologi (Annet vitenskapelig)
  • Sar, Suchandra
    et al.
    Luleå tekniska universitet, Institutionen för samhällsbyggnad och naturresurser, Mineralteknik och metallurgi.
    Sundqvist Ökvist, Lena
    Luleå tekniska universitet, Institutionen för samhällsbyggnad och naturresurser, Mineralteknik och metallurgi.
    Sparrman, Tobias
    Umeå University.
    Engström, Fredrik
    Luleå tekniska universitet, Institutionen för samhällsbyggnad och naturresurser, Geovetenskap och miljöteknik. Luleå tekniska universitet, Institutionen för samhällsbyggnad och naturresurser, Mineralteknik och metallurgi. Luleå tekniska universitet, Institutionen för samhällsbyggnad och naturresurser, Industriell miljö- och processteknik. Luleå tekniska universitet, Institutionen för teknikvetenskap och matematik, Strömningslära och experimentell mekanik.
    Samuelsson, Caisa
    Luleå tekniska universitet, Institutionen för samhällsbyggnad och naturresurser, Mineralteknik och metallurgi. Luleå tekniska universitet, Institutionen för samhällsbyggnad och naturresurser, Industriell miljö- och processteknik.
    Characterization of Double Leached Waelz Oxide for Identification of Fluoirde Mineral2019Inngår i: Metals, ISSN 2075-4701, Vol. 9, nr 3, artikkel-id 361Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Double leached Waelz oxide (DLWO), with 76% zinc, is a secondary zinc containing raw materials obtained by the treatment of electric arc furnace dust. The content of fluoride in DLWO is still too high for direct leaching, as fluoride has a detrimental effect on electrowinning for zinc production. Knowledge of the characteristics of DLWO, and especially on how a fluoride mineral might exist, can contribute to further improvement of the selective leaching for the removal of fluoride. In this study, DLWO was characterized using analytical techniques, such as inductively coupled plasma-optical emission spectroscopy (ICP-OES), 19F liquid-state nuclear magnetic resonance (19F LS NMR), X-ray powder diffraction analysis (XRD), scanning electron microscopy coupled with energy dispersive spectroscopy (SEM-EDS) and 19F solid-state nuclear magnetic resonance (19F SS NMR). This study showed that DLWO mainly consisted of zincite (ZnO), cerussite (PbCO3) and a spinel containing zinc, iron and manganese. The fluoride mineral identified was calcium fluoride (CaF2). In SEM analysis, fluorine was found in larger grains together with calcium and oxygen, which was possibly calcium carbonate.

  • Disputas: 2019-05-10 15:00 D3, Stockholm
    Dastory, Linda
    KTH, Skolan för industriell teknik och management (ITM), Industriell ekonomi och organisation (Inst.), Nationalekonomi.
    Innovation, Technical Change and the Labour Market2019Doktoravhandling, med artikler (Annet vitenskapelig)
    Abstract [en]

    This doctoral thesis consist of four papers. The two first papers are related to financialeconomics and the other two to labour economics. All four papers deal with microeconomicsanalysis of individuals and firms. Where the first two are from a firms perspectiveand the two second once are from an individual perspective. Moreover, all four papersunderline the importance of innovation for productivity,competitiveness and economicgrowth.In the first essay we use German Community Innovation Survey to identify financiallyconstrained firms. Contrary to previous studies we find that the relationship betweenfinancial constraints and firm size is inverted u-shaped and that it is the group ofmedium sized firms which has the largest funding gaps. This is explained by the factthat these firms have high innovation capabilities but at the same time face high cost ofcapital. Furthermore, we test if financial constraints have an impact on firm productivitygrowth. We find negative effects from funding gaps on productivity, but only for investmentin tangible capital and not for innovation investments.The second essay investigates whether there has been a change in the productivityand funding mix of innovative SMEs post stricter bank regulations. Our result showsthat the likelihood of using bank loans as a funding source has not changed for innovationinvestments nor for tangible investments after stricter capital regulations have beenannounced. On the other hand, sources such as subsidies have increased due to regulatoryprograms that have been implemented in the aftermath of the recent financial crisis.Furthermore, SMEs productivity has not changed post stricter bank regulations. Overall,the impact from different sources of funding on productivity is rather limited.The third essay explores firm formation by migrants with a STEM background. Theresult shows that native born STEM workers have a higher probability to form firmsrelative to migrants. Further categorization of migrants shows that refugees are morelikely to become entrepreneurs than EU-labour migrants. Overall, entrepreneurial migrantshave equal or higher predicted income in comparison to native born STEM entrepreneurs.The fourth essay analysis wage effects from changing work tasks using a tasked-basedapproach where workers are mapped in a two dimensional model classified by their cognitiveand routine task content. The result shows clear signs of wage polarization. switchfrom routine and manual tasks to non routine cognitive task yields an average wage premiumof about 2-6%. More importantly, while the gap was 1-5% in the beginning of theperiod, it increased to 10-13% at the end of the period. The result suggest that adaptingnew production technology and innovations to complement analytical skills has a higherand increasing marginal productivity compared to technologies aimed to replace or complementroutinized and manual work tasks. The period of this study is associated withseveral so-called breakthrough technologies such as, computerization, robotization, digitalizationand the introduction of IT technology.

  • Szabó, Mátyás
    Nordiska museet.
    Den nya konsumenten beträder scenen1991Inngår i: 90tal: visioner och vägval, Stockholm: Nordiska museets förlag, 1991, s. 130-154Kapittel i bok, del av antologi (Annet vitenskapelig)
  • Simaeva, I.N.
    et al.
    Immanuel Kant Baltic Federal University, Kaliningrad.
    Budarina, Anna O.
    Immanuel Kant Baltic Federal University, Kaliningrad.
    Sundh, Stellan
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Fakulteten för utbildningsvetenskaper, Institutionen för pedagogik, didaktik och utbildningsstudier.
    Cостояние и привлекательность инклюзивного и специального образования в России и странах Балтии2019Inngår i: Baltic Region, ISSN 2079-8555, Vol. 11, nr 1, s. 76-91Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    In this study, we examine the current state and prospects of inclusive education for learners with special needs and disabilities in the countries of the Baltic region (Poland, Sweden, Germany, Denmark, Latvia, Lithuania, Estonia, Norway, and Russia). We present a SWOT analysis of the development of inclusive education in different countries and analyse its strengths and weaknesses, risks, threats, and challenges from a political, economic, and technological perspective. In our analysis, we dissociate the issue of inclusive education from the problem of teaching learners with disabilities and examine the political, economic, social, and technological aspects of the environment that affect the educational situation of learners with disabilities. We consider inclusive education in the context of the documents of the Euro­pean Agency for Special Needs and Inclusive Education — an active educational institution that facilitates the preparation and adaptation of all learners to life in complex multicultural and integrated societies through rights, freedom, tolerance, and non-discrimination of per­sons with disabilities. Our analysis of inclusive education trends relies on the assessment of the goals and objectives, accessibility, and socio-cultural and economic feasibility of inclu­sive educational systems. We stress political, socio-cultural, and technological differences in practices, dynamics, and prospects for inclusive education in the Baltic region countries and Russia.

  • Disputas: 2019-05-08 09:00 TLS, Carolina Rediviva Library, Uppsala
    Ayyalasomayajula, Kalyan Ram
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Matematisk-datavetenskapliga sektionen, Institutionen för informationsteknologi, Avdelningen för visuell information och interaktion. Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Matematisk-datavetenskapliga sektionen, Institutionen för informationsteknologi, Bildanalys och människa-datorinteraktion.
    Learning based segmentation and generation methods for handwritten document images2019Doktoravhandling, med artikler (Annet vitenskapelig)
    Abstract [en]

    Computerized analysis of handwritten documents is an active research area in image analysis and computer vision. The goal is to create tools that can be available for use at university libraries and for researchers in the humanities. Working with large collections of handwritten documents is very time consuming and many old books and letters remain unread for centuries. Efficient computerized methods could help researchers in history, philology and computer linguistics to cost-effectively conduct a whole new type of research based on large collections of documents. The thesis makes a contribution to this area through the development of methods based on machine learning. The passage of time degrades historical documents. Humidity, stains, heat, mold and natural aging of the materials for hundreds of years make the documents increasingly difficult to interpret. The first half of the dissertation is therefore focused on cleaning the visual information in these documents by image segmentation methods based on energy minimization and machine learning. However, machine learning algorithms learn by imitating what is expected of them. One prerequisite for these methods to work is that ground truth is available. This causes a problem for historical documents because there is a shortage of experts who can help to interpret and interpret them. The second part of the thesis is therefore about automatically creating synthetic documents that are similar to handwritten historical documents. Because they are generated from a known text, they have a given facet. The visual content of the generated historical documents includes variation in the writing style and also imitates degradation factors to make the images realistic. When machine learning is trained on synthetic images of handwritten text, with a known facet, in many cases they can even give an even better result for real historical documents.

  • Lindberg, Jens
    et al.
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för socialt arbete. Umeå universitet, Samhällsvetenskapliga fakulteten, Enheten för demografi och åldrandeforskning (CEDAR).
    Lundgren, Anna Sofia
    Umeå universitet, Humanistiska fakulteten, Institutionen för kultur- och medievetenskaper. Umeå universitet, Samhällsvetenskapliga fakulteten, Enheten för demografi och åldrandeforskning (CEDAR).
    Positioning the ageing subject: Articulations of choice in Swedish and UK health and social care2019Inngår i: Policy Studies, ISSN 0144-2872, E-ISSN 1470-1006, s. 1-19Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    What happens when similar measures are being introduced in different national contexts? This article studies the ways in which patient choice has been articulated in public and official reports on health care in the two contexts of Sweden and the UK, whose welfare systems are typically comprehended as different. Specific interest is directed towards the construction of patient positions, and policy documents are analyzed using discourse theory. The results show many similarities between the national contexts; choice is primarily articulated with individuality, autonomy, consumption, and responsibility, as well as with support from state agencies, and patient choice is relentlessly normalized as the way forward. But there are also important differences that reveal that the presuppositions differ, for example, when pinpointing the stakeholders of patient choice reforms and how the different policies work to take the well-known edges off of patient choice ideology.

  • Adjeiwaah, Mary
    et al.
    Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper.
    Bylund, Mikael
    Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper.
    Lundman, Josef A.
    Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper.
    Söderström, Karin
    Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper.
    Zackrisson, Björn
    Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper.
    Jonsson, Joakim H.
    Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper.
    Garpebring, Anders
    Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper.
    Nyholm, Tufve
    Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper.
    Dosimetric Impact of MRI Distortions: A Study on Head and Neck Cancers2019Inngår i: International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, E-ISSN 1879-355X, Vol. 103, nr 4, s. 994-1003Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Purpose: To evaluate the effect of magnetic resonance (MR) imaging (MRI) geometric distortions on head and neck radiation therapy treatment planning (RTP) for an MRI-only RTP. We also assessed the potential benefits of patient-specific shimming to reduce the magnitude of MR distortions for a 3-T scanner.

    Methods and Materials: Using an in-house Matlab algorithm, shimming within entire imaging volumes and user-defined regions of interest were simulated. We deformed 21 patient computed tomography (CT) images with MR distortion fields (gradient nonlinearity and patient-induced susceptibility effects) to create distorted CT (dCT) images using bandwidths of 122 and 488 Hz/mm at 3 T. Field parameters from volumetric modulated arc therapy plans initially optimized on dCT data sets were transferred to CT data to compute a new plan. Both plans were compared to determine the impact of distortions on dose distributions.

    Results: Shimming across entire patient volumes decreased the percentage of voxels with distortions of more than 2 mm from 15.4% to 2.0%. Using the user-defined region of interest (ROI) shimming strategy, (here the Planning target volume (PTV) was the chosen ROI volume) led to increased geometric for volumes outside the PTV, as such voxels within the spinal cord with geometric shifts above 2 mm increased from 11.5% to 32.3%. The worst phantom-measured residual system distortions after 3-dimensional gradient nonlinearity correction within a radial distance of 200 mm from the isocenter was 2.17 mm. For all patients, voxels with distortion shifts of more than 2 mm resulting from patient-induced susceptibility effects were 15.4% and 0.0% using bandwidths of 122 Hz/mm and 488 Hz/mm at 3 T. Dose differences between dCT and CT treatment plans in D-50 at the planning target volume were 0.4% +/- 0.6% and 0.3% +/- 0.5% at 122 and 488 Hz/mm, respectively.

    Conclusions: The overall effect of MRI geometric distortions on data used for RTP was minimal. Shimming over entire imaging volumes decreased distortions, but user-defined subvolume shimming introduced significant errors in nearby organs and should probably be avoided.

  • Lewin, Leif
    De politiska partiernas uppgång och fall1991Inngår i: 90tal: visioner och vägval, Stockholm: Nordiska museets förlag, 1991, s. 199-210Kapittel i bok, del av antologi (Annet vitenskapelig)
  • Löwnertz, Susanne
    Århundradets skattereform1991Inngår i: 90tal: visioner och vägval, Stockholm: Nordiska museets förlag, 1991, s. 183-198Kapittel i bok, del av antologi (Annet vitenskapelig)