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  • Hudson, Heidi
    The Nordic Africa Institute. Centre of African Studies at the University of Free State, Bloemfontein, South Africa.
    A (Wo)man for all seasons: Amos Tutuola and the Gendering of Peace in Africa2019Report (Other academic)
    Abstract [en]

    This book explores the work of Nigerian author Amos Tutuola and how it can enhance our understanding of gender and peacebuilding in Africa. Critical feminist contributions on how a gender perspective can broaden inclusion in post-conflict processes, as well as change institutions and mindsets are surely innovative but have not succeeded in dislodging liberal peace as the means of dealing with conflict on the African continent. Such works also draw their critiques from largely rationalist, Western roots.Entering Tutuola’s world, where human and non-human characters change and interchange, allows scholars and practitioners to see peacebuilding as organic, reliant on multiple identities and interlocutors, and grounded in local knowledge. I contend that such an expanded lens that integrates exogenous and endogenous knowledge systems non-hierarchically is not only relevant to the peacebuilding context, but could also find application in other areas in need of decolonisation.

  • Murithi, Tim
    The Nordic Africa Institute. Centre for African and Gender Studies, University of the Free State, Bloemfontein, South Africa; Institute for Justice and Reconciliation, Cape Town, South Africa.
    Regional Reconciliation in Africa: The Elusive Dimension of Peace and Security2019Report (Other academic)
    Abstract [en]

    Africa has endured the debilitating effects of cyclical violent conflict for several decades. Despite the existence of well-intentioned policy frameworks and the use of significant resources to stabilise countries, conflicts in the region have remained resistant to resolution. Africa’s crises demonstrate that conflicts have a tendency to spill across borders, affecting communities in more than one country. These cases challenge reductionist understandings of traditional interstate and intra-state wars across the continent. The regional nature of conflicts means that the notion of ‘civil war’ is anachronistic, with increasingly limited descriptive utility.This paper argues that unless concrete efforts are geared towards dealing with the past and promoting regional reconciliation in Africa, the consolidation of peace and security will remain an elusive quest. More specifically, if state resources were deployed in equal measure to lay the foundations for regional reconciliation, this would ultimately be a more effective way to stabilise countries and improve relations with their neighbours. In fact, the pursuit of regional reconciliation could contribute towards the fulfilment of the incomplete project of decolonisation across Africa.

  • Gustavsson, Jan-Helmer (Contributor)
    Skeppsvrak: allmänna råd till 2 kap. lagen om kulturminnen m.m.1990Book (Other academic)
  • Illerstad, Lennart
    Nya svenska kyrkor. D. 2, Götaland1993Book (Other academic)
  • Bennett Gårdö, Monica (Contributor)
    Jordbrukets byggnader: kulturvärden i landskapet1993Book (Other academic)
  • Peters, Harry P. F.
    et al.
    Unilever Res Labs, Olivier van Noortlaan 120, Vlaardingen, Netherlands.
    Schrauwen, Patrick
    Maastricht Univ, Med Ctr, NUTRIM Sch Nutr & Translat Res Metab, Dept Human Biol, Maastricht, Netherlands.
    Verhoef, Petra
    Unilever Res Labs, Olivier van Noortlaan 120, Vlaardingen, Netherlands.
    Byrne, Christopher D.
    Univ Southampton, Fac Med, Nutr & Metab, Southampton, Hants, England;Univ Hosp Southampton, Southampton Natl Inst Hlth Res, Biomed Res Ctr, Southampton, Hants, England.
    Mela, David J.
    Unilever Res Labs, Olivier van Noortlaan 120, Vlaardingen, Netherlands.
    Pfeiffer, Andreas F. H.
    Charite Univ Med Berlin, Dept Endocrinol Diabet & Nutr, Campus Benjamin Franklin, Berlin, Germany;German Inst Human Nutr, Dept Clin Nutr, Potsdam, Germany;DZD, German Ctr Diabet Res, Neuherberg, Germany.
    Risérus, Ulf
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism.
    Rosendaal, Frits R.
    Leiden Univ, Med Ctr, Dept Clin Epidemiol, Leiden, Netherlands.
    Schrauwen-Hinderling, Vera
    Maastricht Univ, Med Ctr, NUTRIM Sch Nutr & Translat Res Metab, Dept Human Biol, Maastricht, Netherlands;Maastricht Univ, Med Ctr, NUTRIM Sch Nutr & Translat Res Metab, Dept Radiol, Maastricht, Netherlands.
    Liver fat: a relevant target for dietary intervention? Summary of a Unilever workshop2017In: Journal of Nutritional Science, ISSN 2048-6790, E-ISSN 2048-6790, Vol. 6, article id e15Article, review/survey (Refereed)
    Abstract [en]

    Currently it is estimated that about 1 billion people globally have non-alcoholic fatty liver disease (NAFLD), a condition in which liver fat exceeds 5 % of liver weight in the absence of significant alcohol intake. Due to the central role of the liver in metabolism, the prevalence of NAFLD is increasing in parallel with the prevalence of obesity, insulin resistance and other risk factors of metabolic diseases. However, the contribution of liver fat to the risk of type 2 diabetes mellitus and CVD, relative to other ectopic fat depots and to other risk markers, is unclear. Various studies have suggested that the accumulation of liver fat can be reduced or prevented via dietary changes. However, the amount of liver fat reduction that would be physiologically relevant, and the timeframes and dose-effect relationships for achieving this through different diet-based approaches, are unclear. Also, it is still uncertain whether the changes in liver fat per se or the associated metabolic changes are relevant. Furthermore, the methods available to measure liver fat, or even individual fatty acids, differ in sensitivity and reliability. The present report summarises key messages of presentations from different experts and related discussions from a workshop intended to capture current views and research gaps relating to the points above.

  • Abelsson, Anna
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Nursing Science.
    Lundberg, Lars
    University of Borås, Prehospen-Centre for Prehospital Research, Borås, Sweden.
    Prehospital CPR training performed with visual feedback2018In: Disaster and Emergency Medicine Journal, ISSN 2451-4691, Vol. 3, no 2, p. 41-45Article in journal (Refereed)
    Abstract [en]

    INTRODUCTION: Swedish firefighters are a part of the emergency medical services. Therefore, they perform prehospital cardiopulmonary resuscitation (CPR) on a regular basis. Training becomes crucial for maintaining the CPR skills and increasing the patients’ chances of survival. Training with visual feedback is for Swedish firefighters a new way of training CPR. The aim of this study was to evaluate firefighters’ perception of a CPR manikin with visual feedback.

    METHOD: This study had a qualitative approach. Data were collected by interviews with 16 firefighters after performing CPR on a manikin with visual feedback. The data were analyzed with a manifest content analysis.

    RESULTS: Visual feedback makes it easy to identify and maintain correct compression rate. There is a need for identifying too deep compressions. Uncertainty regarding the closeness to the stomach arises when using the whole hand during compressions instead of just the wrist. To accomplish an open airway requires a bit of adjustment of the manikins’ head.

    DISCUSSION: To train and learn CPR is feasible with visual feedback. The firefighters can maintaing a correct compression rate and correct compression depth during the sessions. Ventilating a patient with bag-valvemask or pocket mask may require training with visual feedback to guarantee the firefighters being able to secure an open airway of the patient. All these skills are essential and improve the chance of survival for the patients.

  • Abelsson, Anna
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Nursing Science.
    The case of the women with the broken heart2018In: Disaster and Emergency Medicine Journal, ISSN 2451-4691, Vol. 3, no 2, p. 67-68Article in journal (Refereed)
    Abstract [en]

    Takotsubo can be detected as a kindred disease, predominantly affecting post-menopausal women. By correctly identifying these patients as having an acute heart failure syndrome, the outcome can be favorable.

  • Svensson, Sören
    Utförare miljöövervakning, Lunds universitet, biologiska institutionen.
    Bevakning av häckningsframgången hos staren. Årsrapport för 20092010Report (Other academic)
    Abstract [sv]

    (1) Antal starar som skrider till häckning i bevakningsområdena och som således ligger till grund för analys av häckningens förlopp och produktionen av ungar samt möjliggör provtagning för miljögiftsanalyser är efter uppsättning av kompletteringsholkar i vissa av områdena nu helt tillfredsställande i Grimsö, Kvismaren, Tiveden, Svartedalen, Fleringe, Ottenby och Revinge. I Berg har antal häckningar minskat och om trenden inte vänder kan en kompletterande holkgrupp komma att behövas. För Tyresta behövs ett kompletterings- eller ersättningsområde. (2) Den genomsnittliga äggkullstorleken var hög 2009, men andelen flygga ungar var däremot låg i förhållande till vad som gällt under senare delen av 1990-talet och 2000-talet. Den var dock högre än många år under 1980-talet och första delen av 1990-talet. Långsiktigt över hela bevakningsperioden sedan början av 1980-talet finns inga övergripande negativa trender. (3) Äggläggningen startade 2009 tidigare än någonsin i flera av områdena och nytt tidighetsrekord slogs i en holk i Fleringe där första ägget lades 16 april. Starens häckningsstart och häckningsframgång är känsliga för vårens väder och därför indikatorer på effekter av klimatförändringar.

  • Andersson, Per
    et al.
    Linköping University, Department of Behavioural Sciences and Learning, Education and Adult Learning. Linköping University, Faculty of Educational Sciences.
    Nyström, Sofia
    Linköping University, Department of Behavioural Sciences and Learning, Education and Adult Learning. Linköping University, Faculty of Educational Sciences.
    Skonhoft Johannesen, Hedvig
    OsloMet - Oslo Metropolitan University, Norway.
    Editorial: Spring 20182018In: Nordic Journal of Vocational Education and Training, ISSN 2242-458X, E-ISSN 2242-458X, Vol. 8, no 1, p. iii-vArticle in journal (Other academic)
    Abstract [en]

    Welcome to a new volume of the Nordic Journal of Vocational Education and Training. In this first issue of 2018 we are proud to present a new associate editor of our journal. Associate professor Hedvig Skonhoft Johannesen from OsloMet - Oslo Metropolitan University in Norway has joined the editorial group, and we look forward to fruitful cooperation with the journal. In this issue of NJVET we have seven contributions ᅵ six peer-reviewed research articles and one magazine article ᅵ from Sweden, Norway, and Denmark. The topics of the articles address assessment in empirical and analytical approaches, VET studentsᅵ as well as teachersᅵ boundary learning, digital storytelling as an approach to vocational didactics, drop out from vocational education, and finally the quality of vocational education.

  • Andersson, Per
    Linköping University, Department of Behavioural Sciences and Learning, Education and Adult Learning. Linköping University, Faculty of Educational Sciences.
    Editorial: A developing journal2016In: Nordic Journal of Vocational Education and Training, ISSN 2242-458X, E-ISSN 2242-458X, Vol. 6, no 2, p. iii-ivArticle in journal (Other academic)
  • Wiberg, Marie
    Umeå University, Faculty of Social Sciences, Umeå School of Business and Economics (USBE), Statistics.
    The relationship between TIMSS mathematics achievements, grades and national test scores2019In: Education Inquiry, ISSN 2000-4508, E-ISSN 2000-4508Article in journal (Refereed)
    Abstract [en]

    The aim of this paper was to examine the relationship between Trends in Mathematics and Science Study (TIMSS) mathematics achievement and the two school achievement measures of grades and national test results in Sweden. A further aim was to examine the association of TIMSS mathematics achievement with different subgroups of students. The results show that there is a strong positive relationship between TIMSS mathematics achievement and national tests and obtained grades from both grade 6 and grade 9. Students from more educated homes performed better overall on TIMSS than those from less-educated homes, and the relationships between TIMSS and the school achievement measures were stronger for students from more educated home backgrounds. The school context and the students’ background had an impact on the students’ TIMSS result. The results have implications for how one should view the results from TIMSS as a measure of student mathematics achievement and thus how TIMSS results can be used in a national context.

  • Abelsson, Anna
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Nursing Science.
    Lundberg, Lars
    Swedish Armed Forces Centre for Defence Medicine, Sweden.
    CPR performed in battlefield emergency care2019In: Australasian Journal of Paramedicine, ISSN 2202-7270, Vol. 16, p. 1-9Article in journal (Refereed)
    Abstract [en]

    Introduction

    During military missions medical care is provided to military personnel as well as civilians. Although cardiopulmonary resuscitation (CPR) may not be a common task in a military field hospital, all personnel need to be trained to deal with cardiac arrest.

    Methods

    This study was a comparative simulation study. Participants (n=36) from the Swedish armed forces performed CPR for 2 minutes at one of three different locations: at ground level, a military bed, or a transportable military stretcher. Compression depth and rate after 2 minutes of CPR and at the time of the participants’ own request to be relieved were measured. Descriptive and inferential analysis was conducted.

    Results

    There is a direct correlation between compression depth and working level, concluding that the higher working level, the lower the compression depth. There is in total an overall low percentage of participants within limits for correctly conducted CPR regarding both compression depth and rate. Time to fatigue is related to working level, where increased level results in early fatigue.

    Conclusion

    The quality of CPR is affected by the level at which it is performed. The quality of CPR was satisfactory when working at ground level, but suboptimal when working at hospital bed level or military stretcher level. When working at raised levels, participants appeared to misjudge their own compression depth and rate. This may indicate that changes are needed when CPR is practised in the military hospital setting. Future studies regarding the use footstools are required due to the height of military beds and transportable stretchers.

  • Beskow-Sjöberg, Margareta
    Ölands järnåldersgravfält. Vol. 2, Högsrum, Glömminge, Algutsrum, Torslunda, Långlöt, Runsten, Norra Möckleby och Gårdby1991Book (Other academic)
  • Public defence: 2019-03-15 09:00 Enghoffsalen, Uppsala
    Schart-Morén, Nadine
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Otolaryngology and Head and Neck Surgery.
    The Human Cochlea and Cochlear Implantation: Morphological Characteristics and Clinical Correlations2018Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    The most common sensory deficit in the world is sensorineural hearing loss. Cochlear implantation (CI) can majorly contribute to restore hearing, not only in patients with severe to profound hearing loss, but also in hearing-impaired patients with residual low-frequency hearing. The overall aims of the present thesis were to study human cochlear anatomy in order to improve structural preservation during CI surgery. An archival collection of temporal bones underwent micro-computer tomography and synchrotron radiation phase-contrast imaging (SR-PCI) with 3D reconstructions, new techniques to digitally image and reproduce the human inner ear. Studying the anatomy of the facial nerve and its interaction with the cochlea revealed that a fusion of the two was found in 1.4 % of the specimens (cochlear-facial dehiscence). This may cause facial nerve excitation after CI. CT-scans and intraoperative electrically auditory brainstem response (e-ABR) measurements were analyzed in patients with cochlear-facial dehiscence. A large evoked late myogenic potential at low stimulation levels during intraoperative e-ABR measurements, can foresee excitation at CI activation. The 3D anatomy of the fundus of the inner acoustic canal was also studied, helping to interpret preoperative imaging of the VIIIth nerve before CI. In a subsequent study, SR-PCI reproduced the soft tissue anatomy at the round window region. Results indicated a high risk for trauma at cochleostomy. For optimal preservation, the round window approach was recommended. In a long-term follow-up the first 21 consecutively operated patients in Uppsala, that underwent hearing preservation CI-surgery, data could be retrieved in 15 patients. Pure tone audiometry was assessed preoperatively and at one, three and >5 years following surgery. Insertion angle, number of electrodes inside the cochlea, user-time of the processor, and stimulation strategies were documented. Results showed that long-term preservation of hearing is possible in most cases. There was a high correlation between insertion depth and preservation of residual hearing. Also, patients with complete hearing loss experienced good performance in speech discrimination and user time.

  • Ullén, Marian (Editor)
    Från romanik till nygotik: studier i kyrklig konst och arkitektur tillägnade Evald Gustafsson1992Book (Other academic)
  • Engdahl, Kerstin (Editor)
    Kaliff, Anders (Editor)
    Religion från stenålder till medeltid: artiklar baserade på Religionsarkeologiska nätverksgruppens konferens på Lövstadbruk den 1-3 december 19951996Book (Other academic)
  • Sandholm, Kerstin
    et al.
    Linnaeus Univ, Linnaeus Ctr Biomat Chem, Kalmar, Sweden.
    Persson, Barbro
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Immunology, Genetics and Pathology, Clinical Immunology.
    Skattum, Lillemor
    Lund Univ, Sect Microbiol, Dept Lab Med Immunol & Glycobiol, Lund, Sweden.
    Eggertsen, Gosta
    Karolinska Inst, Dept Lab Med, Stockholm, Sweden;Karolinska Univ Lab, Clin Chem, Stockholm, Sweden.
    Nyman, Dag
    Aland Cent Hosp, Aland Borrelia Grp, Mariehamn, Finland.
    Gunnarsson, Iva
    Karolinska Inst, Karolinska Univ Hosp, Dept Med, Rheumatol Unit, Stockholm, Sweden.
    Svenungson, Elisabet
    Karolinska Inst, Karolinska Univ Hosp, Dept Med, Rheumatol Unit, Stockholm, Sweden.
    Nilsson, Bo
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Immunology, Genetics and Pathology, Clinical Immunology.
    Nilsson Ekdahl, Kristina
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Immunology, Genetics and Pathology, Clinical Immunology. Linnaeus Univ, Linnaeus Ctr Biomat Chem, Kalmar, Sweden.
    Evaluation of a Novel Immunoassay for Quantification of C1q for Clinical Diagnostic Use2019In: Frontiers in Immunology, ISSN 1664-3224, E-ISSN 1664-3224, Vol. 10, article id 7Article in journal (Refereed)
    Abstract [en]

    Objectives: C1q is a valuable biomarker of disease activity in systemic lupus erythematosus (SLE). The "gold standard" assay, rocket immunoelectrophoresis (RIE), is time-consuming, and thus a shift to soluble immune precipitation techniques such as nephelometry has occurred. However, quantification of C1q with these techniques has been questioned as a result of the antibody binding properties of C1q. In the present work, we have compared results using various techniques (RIE, nephelometry, and ELISA) and have developed and validated a new magnetic bead-based sandwich immunoassay (MBSI). Methods: C1q was quantified by nephelometry and the new sandwich immunoassay in 45 serum samples analyzed using RIE. C1q was also assessed in plasma using RIE and sandwich immunoassay in samples from SLE patients with nephritis (n = 69), SLE patients without nephritis (n = 310) as classified by BILAG score, and matched controls (n = 322). In addition, cerebrospinal fluid (CSF) samples from 31 patients, previously analyzed with ELISA, were also analyzed with the MBSI to test the behavior of this new assay in the lower detection range. Results: We found a strong correlation between the new MBSI, RIE, and ELISA, but not with nephelometry. The MBSI demonstrated lower levels of C1q in SLE patients than in matched controls (p < 0.0001), and patients with nephritis had lower levels than patients without nephritis (p < 0.01). Similarily, RIE showed significant differences between the patient groups (p < 0.0001). An association was also found between the levels of C1q and the SLE disease activity index (SLEDAI). Furthermore, there was good correlation between the values obtained by MBSI and ELISA, in both serum (r = 0.960) and CSF (r = 0.786), underscoring the ability of both techniques to measure low concentrations of C1q with high accuracy. Conclusion: The sandwich immunoassay correlated well with RIE, but soluble immune precipitation techniques, such as nephelometry, did not appear suitable alternatives, since C1q itself, and possibly anti-C1q antibodies, interfered with the measurements. The new sandwich immunoassay is therefore a good replacement for RIE in monitoring SLE disease activity.

  • Ranheden, Håkan
    Metodstudier & tolkningsmöjligheter1996Book (Other academic)
  • Grundström, Åke
    et al.
    The Nordic Museum.
    Wallin, Sigurd
    The Nordic Museum.
    Markisens slott: en bildserie från Tyresö1958In: Fatanburen: Nordiska museets och Skansens årsbok, Stockholm: Nordiska museets förlag, 1958, p. 72-94Chapter in book (Other academic)
  • Ablikim, M.
    et al.
    Andersson, Walter Ikegami
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Nuclear Physics.
    Johansson, Tord
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Nuclear Physics.
    Kupsc, Andrzej
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Nuclear Physics.
    Li, Cui
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Nuclear Physics.
    Papenbrock, Michael
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Nuclear Physics.
    Pettersson, Joachim
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Nuclear Physics.
    Schönning, Karin
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Nuclear Physics.
    Wolke, Magnus
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Nuclear Physics.
    Zou, J. H.
    Study of the decay D0→¯K0π−e+νe2019In: Physical Review D: covering particles, fields, gravitation, and cosmology, ISSN 2470-0010, E-ISSN 2470-0029, Vol. 99, no 1, article id 011103Article in journal (Refereed)
    Abstract [en]

    We report a study of the decay D-0 -> (K) over bar (0)pi(-)e(+)nu(e) based on a sample of 2.93 fb(-1) e(+)e(-) annihilation data collected at the center-of-mass energy of 3.773 GeV with the BESIII detector at the BEPCII collider. The total branching fraction is determined to be B(D-0 -> (K) over bar (0)pi(-)e(+)nu(e)) = (1.434 +/- 0.029(stat.) +/- 0.032(syst.))%, which is the most precise to date. According to a detailed analysis of the involved dynamics, we find this decay is dominated with the K*(892)(-) contribution and present an improved measurement of its branching fraction to be B(D-0 -> K*(892)(-)e(+)nu(e) = (2.033 +/- 0.046(stat.) +/- 0.047(syst.))%. We further access their hadronic form-factor ratios for the first time as r(V) = V(0)/A(1)(0) = 1.46 +/- 0.07(stat.) +/- 0.02(syst.) and r(2) = A(2)(0)/A(1)(0) = 0.67 +/- 0.06(stat.) +/- 0.01(syst.). In addition, we observe a significant (K) over bar (0)pi(-) S-wave component accounting for (5.51 +/- 0.97(stat.) +/- 0.62(syst.))% of the total decay rate.

  • Kuehn, Danilo
    et al.
    Univ Potsdam, Inst Phys & Astron, Karl Liebknecht Str 24-25, D-14476 Potsdam, Germany;Helmholtz Zentrum Berlin Mat & Energie GmbH, Albert Einstein Str 15, D-12489 Berlin, Germany.
    Mueller, Moritz
    Univ Basque Country, CSIC, Ctr Fis Mat, Paseo Manuel de Lardizabal 5, E-20018 Donostia San Sebastian, Spain;DIPC, Paseo Manuel de Lardizabal 5, E-20018 Donostia San Sebastian, Spain;CIC nanoGUNE, Ave Tolosa 76, E-20018 Donostia San Sebastian, Spain.
    Sorgenfrei, Florian
    Univ Potsdam, Inst Phys & Astron, Karl Liebknecht Str 24-25, D-14476 Potsdam, Germany;Helmholtz Zentrum Berlin Mat & Energie GmbH, Albert Einstein Str 15, D-12489 Berlin, Germany.
    Giangrisostomi, Erika
    Helmholtz Zentrum Berlin Mat & Energie GmbH, Albert Einstein Str 15, D-12489 Berlin, Germany.
    Jay, Raphael M.
    Univ Potsdam, Inst Phys & Astron, Karl Liebknecht Str 24-25, D-14476 Potsdam, Germany.
    Ovsyannikov, Ruslan
    Helmholtz Zentrum Berlin Mat & Energie GmbH, Albert Einstein Str 15, D-12489 Berlin, Germany.
    Mårtensson, Nils
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Molecular and Condensed Matter Physics.
    Sanchez-Portal, Daniel
    Univ Basque Country, CSIC, Ctr Fis Mat, Paseo Manuel de Lardizabal 5, E-20018 Donostia San Sebastian, Spain;DIPC, Paseo Manuel de Lardizabal 5, E-20018 Donostia San Sebastian, Spain.
    Foehlisch, Alexander
    Univ Potsdam, Inst Phys & Astron, Karl Liebknecht Str 24-25, D-14476 Potsdam, Germany;Helmholtz Zentrum Berlin Mat & Energie GmbH, Albert Einstein Str 15, D-12489 Berlin, Germany.
    Directional sub-femtosecond charge transfer dynamics and the dimensionality of 1T-TaS22019In: Scientific Reports, ISSN 2045-2322, E-ISSN 2045-2322, Vol. 9, article id 488Article in journal (Refereed)
    Abstract [en]

    For the layered transition metal dichalcogenide 1T-TaS2, we establish through a unique experimental approach and density functional theory, how ultrafast charge transfer in 1T-TaS2 takes on isotropic three-dimensional character or anisotropic two-dimensional character, depending on the commensurability of the charge density wave phases of 1T-TaS2. The X-ray spectroscopic core-hole-clock method prepares selectively in-and out-of-plane polarized sulfur 3p orbital occupation with respect to the 1T-TaS2 planes and monitors sub-femtosecond wave packet delocalization. Despite being a prototypical two-dimensional material, isotropic three-dimensional charge transfer is found in the commensurate charge density wave phase (CCDW), indicating strong coupling between layers. In contrast, anisotropic two-dimensional charge transfer occurs for the nearly commensurate phase (NCDW). In direct comparison, theory shows that interlayer interaction in the CCDW phase - not layer stacking variations - causes isotropic three-dimensional charge transfer. This is presumably a general mechanism for phase transitions and tailored properties of dichalcogenides with charge density waves.

  • Artelius, Tore
    Långfärd och återkomst: skeppet i bronsålderns gravar1996 (ed. 1)Book (Other academic)
  • Lundqvist, Lars
    et al.
    Lindeblad, Karin
    Nielsen, Ann-Lili
    Ersgård, Lars
    Slöinge och Borg: stormansgårdar i öst och väst1996Book (Other academic)
  • Johansson, Mattias
    et al.
    IARC, Lyon, France.
    Carreras-Torres, Robert
    IARC, Lyon, France.
    Scelo, Ghislaine
    IARC, Lyon, France.
    Purdue, Mark P.
    NCI, Div Canc Epidemiol & Genet, Dept Hlth & Human Serv, NIH, Bethesda, MD USA.
    Mariosa, Daniela
    IARC, Lyon, France.
    Muller, David C.
    Imperial Coll, London, England.
    Timpson, Nicolas J.
    Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, Avon, England.
    Haycock, Philip C.
    Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, Avon, England.
    Brown, Kevin M.
    NCI, Div Canc Epidemiol & Genet, Dept Hlth & Human Serv, NIH, Bethesda, MD USA.
    Wang, Zhaoming
    St Jude Childrens Res Hosp, Memphis, TN USA.
    Ye, Yuanqing
    Univ Texas MD Anderson Canc Ctr, Dept Epidemiol, Div Canc Prevent & Populat Sci, Houston, TX USA.
    Hofmann, Jonathan N.
    NCI, Div Canc Epidemiol & Genet, Dept Hlth & Human Serv, NIH, Bethesda, MD USA.
    Foll, Matthieu
    IARC, Lyon, France.
    Gaborieau, Valerie
    IARC, Lyon, France.
    Machiela, Mitchell J.
    NCI, Div Canc Epidemiol & Genet, Dept Hlth & Human Serv, NIH, Bethesda, MD USA.
    Colli, Leandro M.
    NCI, Div Canc Epidemiol & Genet, Dept Hlth & Human Serv, NIH, Bethesda, MD USA.
    Li, Peng
    IARC, Lyon, France;Max Planck Inst Demog Res, Rostock, Germany.
    Garnier, Jean-Guillaume
    Ctr Energie Atom & Energies Alternat, Inst Genom, Ctr Natl Genotypage, Evry, France; Ctr Etud Polymorphisme Humain, Fdn Jean Dausset, Paris, France.
    Blanche, Helene
    Ctr Energie Atom & Energies Alternat, Inst Genom, Ctr Natl Genotypage, Evry, France.
    Boland, Anne
    Ctr Energie Atom & Energies Alternat, Inst Genom, Ctr Natl Genotypage, Evry, France.
    Burdette, Laurie
    NCI, Div Canc Epidemiol & Genet, Dept Hlth & Human Serv, NIH, Bethesda, MD USA.
    Prokhortchouk, Egor
    Russian Acad Sci, Fed Res Ctr Fundamentals Biotechnol, Moscow, Russia.
    Skryabin, Konstantin G.
    Russian Acad Sci, Fed Res Ctr Fundamentals Biotechnol, Moscow, Russia; Kurchatov Sci Ctr, Moscow, Russia.
    Yeager, Meredith
    NCI, Div Canc Epidemiol & Genet, Dept Hlth & Human Serv, NIH, Bethesda, MD USA.
    Radojevic-Skodric, Sanja
    Univ Belgrade Sch Med, Inst Pathol, Belgrade, Serbia; Clin Ctr Serbia, Clin Urol, Belgrade, Serbia.
    Ognjanovic, Simona
    Mayo Clin, Grad Sch Biomed Sci, Rochester, MN USA; IOCPR, Belgrade, Serbia.
    Foretova, Lenka
    Masaryk Mem Canc Inst, Dept Canc Epidemiol & Genet, Brno, Czech Republic.
    Holcatova, Ivana
    Charles Univ Prague, Fac Med 2, Inst Publ Hlth & Prevent Med, Prague, Czech Republic.
    Janout, Vladimir
    Palacky Univ, Fac Med, Dept Prevent Med, Olomouc, Czech Republic.
    Mates, Dana
    Natl Inst Publ Hlth, Bucharest, Romania.
    Mukeriya, Anush
    Russian NN Blokhin Canc Res Ctr, Moscow, Russia.
    Rascu, Stefan
    Carol Davila Univ Med & Pharm, Th Burghele Hosp, Bucharest, Romania.
    Zaridze, David
    Russian NN Blokhin Canc Res Ctr, Moscow, Russia.
    Bencko, Vladimir
    Charles Univ Prague, Fac Med 1, Inst Hyg & Epidemiol, Prague, Czech Republic.
    Cybulski, Cezary
    Pomeranian Med Univ, Dept Genet & Pathol, Int Hereditary Canc Ctr, Szczecin, Poland.
    Fabianova, Eleonora
    Reg Author Publ Hlth Banska Bystr, Banska Bystrica, Slovakia.
    Jinga, Viorel
    Carol Davila Univ Med & Pharm, Th Burghele Hosp, Bucharest, Romania.
    Lissowska, Jolanta
    M Sklodowska Curie Canc Ctr, Warsaw, Poland; Inst Oncol, Warsaw, Poland.
    Lubinski, Jan
    Pomeranian Med Univ, Dept Genet & Pathol, Int Hereditary Canc Ctr, Szczecin, Poland.
    Navratilova, Marie
    Masaryk Mem Canc Inst, Dept Canc Epidemiol & Genet, Brno, Czech Republic.
    Rudnai, Peter
    Natl Publ Hlth Ctr, Natl Directorate Environm Hlth, Budapest, Hungary.
    Benhamou, Simone
    INSERM, U946, Paris, France; CNRS, Inst Gustave Roussy, UMR 8200, Villejuif, France.
    Cancel-Tassin, Geraldine
    CeRePP, Paris, France; UPMC Univ Paris 06, Inst Univ Cancerol, GRC 5, Paris, France.
    Cussenot, Olivier
    CeRePP, Paris, France; UPMC Univ Paris 06, Inst Univ Cancerol, GRC 5, Paris, France; Hopitaux Univ Est Parisien Tenon, AP HP, Dept Urol, Paris, France.
    Weiderpass, Elisabete
    Canc Registry Norway, Inst Population Based Canc Res, Dept Res, Oslo, Norway; Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden; Folkhalsan Res Ctr, Genet Epidemiol Grp, Helsinki, Finland; Arctic Univ Norway, Univ Tromso, Dept Community Med, Tromso, Norway.
    Ljungberg, Borje
    Umeå Univ, Dept Surg & Perioperat Sci Urol & Androl, Umeå, Sweden.
    Sitaram, Raviprakash Tumkur
    Umeå Univ, Dept Surg & Perioperat Sci Urol & Androl, Umeå, Sweden.
    Häggström, Christel
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Endocrine Surgery. Umeå Univ, Dept Biobank Res, Umeå, Sweden.
    Bruinsma, Fiona
    Canc Council Victoria, Canc Epidemiol Ctr, Melbourne, Vic, Australia.
    Jordan, Susan J.
    QIMR Berghofer Med Res Inst, Herston, Qld, Australia; Univ Queensland, Sch Publ Hlth, Brisbane, Qld, Australia.
    Severi, Gianluca
    Univ Paris Saclay, Univ Paris Sud, Hlth Generat Team, CESP,INSERM,Fac Med,UVSQ,Gustave Roussy, Villejuif, France; Human Genet Fdn HuGeF, Turin, Italy.
    Winship, Ingrid
    Univ Melbourne, Royal Melbourne Hosp, Dept Med, Melbourne, Vic, Australia.
    Hveem, Kristian
    Norwegian Univ Sci & Technol, Dept Publ Hlth, KG Jebsen Ctr Genet Epidemiol, Trondheim, Norway.
    Vatten, Lars J.
    Norwegian Univ Sci & Technol, Fac Med, Dept Publ Hlth & Gen Practice, Trondheim, Norway.
    Fletcher, Tony
    Univ London, London Sch Hyg & Trop Med, London, England.
    Larsson, Susanna C.
    Karolinska Inst, Inst Environm Med, Stockholm, Sweden.
    Wolk, Alicja
    Karolinska Inst, Inst Environm Med, Stockholm, Sweden.
    Banks, Rosamonde E.
    Univ Leeds, St Jamess Univ Hosp, Leeds Inst Canc & Pathol, Leeds, W Yorkshire, England.
    Selby, Peter J.
    Imperial Coll London, St Marys Hosp, Div Surg, Natl Inst Hlth Res Diagnost Evidence Cooperat, London, England.
    Easton, Douglas F.
    Univ Cambridge, Dept Oncol, Cambridge, England; Univ Cambridge, Dept Publ Hlth & Primary Care, Cambridge, England.
    Andreotti, Gabriella
    NCI, Div Canc Epidemiol & Genet, Dept Hlth & Human Serv, NIH, Bethesda, MD USA.
    Freeman, Laura E. Beane
    NCI, Div Canc Epidemiol & Genet, Dept Hlth & Human Serv, NIH, Bethesda, MD 20892 USA.
    Koutros, Stella
    NCI, Div Canc Epidemiol & Genet, Dept Hlth & Human Serv, NIH, Bethesda, MD 20892 USA.
    Mannisto, Satu
    Natl Inst Hlth & Welf, Helsinki, Finland.
    Weinstein, Stephanie
    NCI, Div Canc Epidemiol & Genet, Dept Hlth & Human Serv, NIH, Bethesda, MD 20892 USA.
    Clark, Peter E.
    Vanderbilt Ingram Canc Ctr, Nashville, TN USA.
    Edwards, Todd L.
    Vanderbilt Genet Inst, Vanderbilt Ingram Canc Ctr, Div Epidemiol, Dept Med, Nashville, TN USA.
    Lipworth, Loren
    Vanderbilt Ingram Canc Ctr, Nashville, TN USA.
    Gapstur, Susan M.
    Amer Canc Soc, Atlanta, GA 30329 USA.
    Stevens, Victoria L.
    Amer Canc Soc, Atlanta, GA 30329 USA.
    Carol, Hallie
    Dana Farber Canc Inst, Boston, MA 02115 USA.
    Freedman, Matthew L.
    Dana Farber Canc Inst, Boston, MA 02115 USA.
    Pomerantz, Mark M.
    Dana Farber Canc Inst, Boston, MA 02115 USA.
    Cho, Eunyoung
    Brown Univ, Providence, RI 02912 USA.
    Wilson, Kathryn M.
    Harvard TH Chan Sch Publ Hlth, Boston, MA USA.
    Gaziano, J. Michael
    Harvard Med Sch, Brigham & Womens Hosp, Boston, MA USA.
    Sesso, Howard D.
    Harvard TH Chan Sch Publ Hlth, Boston, MA USA; Brigham & Womens Hosp, Dept Med, 75 Francis St, Boston, MA 02115 USA.
    Freedman, Neal D.
    NCI, Div Canc Epidemiol & Genet, Dept Hlth & Human Serv, NIH, Bethesda, MD 20892 USA.
    Parker, Alexander S.
    Mayo Clin, Dept Hlth Sci Res, Jacksonville, FL 32224 USA.
    Eckel-Passow, Jeanette E.
    Mayo Clin, Dept Hlth Sci Res, Div Biomed Stat & Informat, Rochester, MN USA.
    Huang, Wen-Yi
    NCI, Div Canc Epidemiol & Genet, Dept Hlth & Human Serv, NIH, Bethesda, MD 20892 USA.
    Kahnoski, Richard J.
    Spectrum Hlth, Div Urol, Grand Rapids, MI USA.
    Lane, Brian R.
    Spectrum Hlth, Div Urol, Grand Rapids, MI USA; Michigan State Univ, Coll Human Med, Grand Rapids, MI USA.
    Noyes, Sabrina L.
    Van Andel Res Inst, Ctr Canc Genom & Quantitat Biol, Grand Rapids, MI USA; Spectrum Hlth, Grand Rapids, MI USA.
    Petillo, David
    Van Andel Res Inst, Ctr Canc Genom & Quantitat Biol, Grand Rapids, MI USA; Ferris State Univ, Diagnost Program, Grand Rapids, MI USA.
    Teh, Bin Tean
    Van Andel Res Inst, Ctr Canc Genom & Quantitat Biol, Grand Rapids, MI USA; Natl Univ Singapore, Med Sch, Program Canc & Stem Cell Biol, Duke Natl, Singapore, Singapore; ASTAR, Inst Mol & Cell Biol, Singapore, Singapore; Natl Canc Ctr Singapore, Div Med Sci, Lab Canc Epigenome, Singapore, Singapore; Natl Univ Singapore, Canc Sci Inst Singapore, Singapore, Singapore.
    Peters, Ulrike
    Fred Hutchinson Canc Res Ctr, Canc Prevent Program, 1124 Columbia St, Seattle, WA 98104 USA.
    White, Emily
    Fred Hutchinson Canc Res Ctr, Canc Prevent Program, 1124 Columbia St, Seattle, WA 98104 USA.
    Anderson, Garnet L.
    Fred Hutchinson Canc Res Ctr, WHI Clin Coordinating Ctr, 1124 Columbia St, Seattle, WA 98104 USA.
    Johnson, Lisa
    Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA.
    Luo, Juhua
    Indiana Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Bloomington, IN USA.
    Buring, Julie
    Harvard Med Sch, Brigham & Womens Hosp, Boston, MA USA; Brigham & Womens Hosp, Dept Med, 75 Francis St, Boston, MA 02115 USA.
    Lee, I-Min
    Harvard Med Sch, Brigham & Womens Hosp, Boston, MA USA; Brigham & Womens Hosp, Dept Med, 75 Francis St, Boston, MA 02115 USA.
    Chow, Wong-Ho
    Univ Texas MD Anderson Canc Ctr, Dept Epidemiol, Div Canc Prevent & Populat Sci, Houston, TX 77030 USA.
    Moore, Lee E.
    NCI, Div Canc Epidemiol & Genet, Dept Hlth & Human Serv, NIH, Bethesda, MD 20892 USA.
    Eisen, Timothy
    Univ Cambridge, Cambridge, England.
    Henrion, Marc
    Inst Canc Res, London, England; Icahn Sch Med Mt Sinai, Dept Genet & Genom Sci, New York, NY 10029 USA.
    Larkin, James
    Royal Marsden NHS Fdn Trust, London, England.
    Barman, Poulami
    Mayo Clin, Dept Hlth Sci Res, Div Biomed Stat & Informat, Rochester, MN USA.
    Leibovich, Bradley C.
    Mayo Clin, Dept Urol, Rochester, MN USA.
    Choueiri, Toni K.
    Dana Farber Canc Inst, Boston, MA 02115 USA.
    Lathrop, G. Mark
    McGill Univ, Montreal, PQ, Canada;Genome Quebec Innovat Ctr, Montreal, PQ, Canada.
    Deleuze, Jean-Francois
    Ctr Energie Atom & Energies Alternat, Inst Genom, Ctr Natl Genotypage, Evry, France; Ctr Etud Polymorphisme Humain, Fdn Jean Dausset, Paris, France.
    Gunter, Marc
    IARC, Lyon, France.
    McKay, James D.
    IARC, Lyon, France.
    Wu, Xifeng
    Univ Texas MD Anderson Canc Ctr, Dept Epidemiol, Div Canc Prevent & Populat Sci, Houston, TX 77030 USA.
    Houlston, Richard S.
    Inst Canc Res, London, England.
    Chanock, Stephen J.
    NCI, Div Canc Epidemiol & Genet, Dept Hlth & Human Serv, NIH, Bethesda, MD 20892 USA.
    Relton, Caroline
    Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, Avon, England; Univ Bristol, Sch Social & Community Med, Bristol, Avon, England.
    Richards, J. Brent
    McGill Univ, Jewish Gen Hosp, Dept Med, Montreal, PQ, Canada;McGill Univ, Jewish Gen Hosp, Dept Human Genet, Montreal, PQ, Canada;McGill Univ, Jewish Gen Hosp, Dept Epidemiol & Biostat, Montreal, PQ, Canada.
    Martin, Richard M.
    Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, Avon, England; Univ Bristol, Sch Social & Community Med, Bristol, Avon, England; Univ Bristol, Univ Hosp Bristol NHS Fdn Trust, Natl Inst Hlth Res, Bristol Nutr Biomed Res Unit, Bristol, Avon, England.
    Smith, George Davey
    Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, Avon, England; Univ Bristol, Sch Social & Community Med, Bristol, Avon, England.
    Brennan, Paul
    IARC, Lyon, France.
    The influence of obesity-related factors in the etiology of renal cell carcinoma—A mendelian randomization study2019In: PLoS Medicine, ISSN 1549-1277, E-ISSN 1549-1676, Vol. 16, no 1, article id e1002724Article in journal (Refereed)
    Abstract [en]

    Background: Several obesity-related factors have been associated with renal cell carcinoma (RCC), but it is unclear which individual factors directly influence risk. We addressed this question using genetic markers as proxies for putative risk factors and evaluated their relation to RCC risk in a mendelian randomization (MR) framework. This methodology limits bias due to confounding and is not affected by reverse causation.

    Methods and findings: Genetic markers associated with obesity measures, blood pressure, lipids, type 2 diabetes, insulin, and glucose were initially identified as instrumental variables, and their association with RCC risk was subsequently evaluated in a genome-wide association study (GWAS) of 10,784 RCC patients and 20,406 control participants in a 2-sample MR framework. The effect on RCC risk was estimated by calculating odds ratios (ORSD) for a standard deviation (SD) increment in each risk factor. The MR analysis indicated that higher body mass index increases the risk of RCC (ORSD: 1.56, 95% confidence interval [CI] 1.44–1.70), with comparable results for waist-to-hip ratio (ORSD: 1.63, 95% CI 1.40–1.90) and body fat percentage (ORSD: 1.66, 95% CI 1.44–1.90). This analysis further indicated that higher fasting insulin (ORSD: 1.82, 95% CI 1.30–2.55) and diastolic blood pressure (DBP; ORSD: 1.28, 95% CI 1.11–1.47), but not systolic blood pressure (ORSD: 0.98, 95% CI 0.84–1.14), increase the risk for RCC. No association with RCC risk was seen for lipids, overall type 2 diabetes, or fasting glucose.

    Conclusions: This study provides novel evidence for an etiological role of insulin in RCC, as well as confirmatory evidence that obesity and DBP influence RCC risk.

  • Gren, Leif
    Fossil åkermark1991Book (Other academic)
  • Public defence: 2019-03-19 13:15 O102, Sundsvall
    Hammarling, Krister
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Electronics Design.
    Hydrogel-based pH-sensors: Development and characterisation of optical and electrical pH sensors based on stimuli-responsive hydrogels2019Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    The ability to measure the chemical parameter pH is of high importance in many areas. With new government regulations and evolving markets, there is a strong motivation for improving such measurements and conducting research on new types of pH sensors and sensor materials. Stimuli-responsive hydrogels (a group of polymers) have attracted a lot of attention in recent decades, due to their ability to be customized to suit many applications. One specific area where they have attracted attention is pH sensor technology.

    Two stimuli-responsive hydrogels are used in this thesis. One is a non-toxic hydrogel, 1,4-acryl-terminated oligo(beta-amino esters) (1,4-AOBAE). Although it was previously used in drug- and DNA- delivery systems, it has not (to my knowledge) been used in a sensor configuration, and thus it is interesting to study. The second hydrogel, 1,3-acryl-terminated oligo(beta-amino esters) (1,3-AOBAE), is an improved variant of the first one. This improved hydrogel was synthesized because the original hydrogel crystallizes at room temperature, which meant that it was not optimal for various coating techniques. This hydrogel was characterized and verified for pH responsivity in two sensor configurations: electrical and optical. Designing a hydrogel for a specific application can be a complex procedure due to the many synthesizing parameters. For example, increasing a hydrogel's mechanical strength by introducing a higher degree of cross linking, leads to a smaller mesh size, which in turn leads to a lower diffusion rate and less solution absorption. The two hydrogels examined in this thesis respond to pH changes by absorbing or desorbing water; this change in the hydrogel's water content also changes its effective refractive index and permittivity. These changes can be measured using optical or electrical sensor systems. Three types of sensor systems were used in this thesis to verify the hydrogel's pH response and to ensure that they are suitable for use in thin-film techniques on various substrates (e.g. glass and plastic). The experimental results prove that these hydrogels are suitable for use in both electrical and optical sensor configurations. For electrical systems, a pH range of approximately 3-12 was achieved, and for optical, the range was approximately 2-12. These ranges can likely be improved, as the sensor film delaminated from the substrate at low pHs due to adhesion problems and as measurements above 12 were not conducted.

    The findings of this thesis could, after more research, have strong implications for the development of improved pH-sensor configurations, especially for medical and healthcare applications and in environmental monitoring.

  • Public defence: 2019-03-14 09:00 Rudbecksalen, C11, Uppsala
    Asif, Sana
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Immunology, Genetics and Pathology, Clinical Immunology.
    Regulation of thromboinflammation in therapeutic medicine: Special focus on surface coating strategies2019Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    Biomaterials are an integral part of modern health care and offer potential treatment modalities to diseases and conditions otherwise intractable. However, the critical issue herein is incompatibility reactions.

    Our innate immune system is fundamental in protection against pathogens and foreign intruders and controls the discrimination between self and non-self. Biomaterials come in contact with blood upon implantation where they are sensed by innate immune mediators which through a cascade of complex, multifaceted reactions induce inflammation as well as thrombosis which may induce biomaterial dysfunction and rejection. This explains why patients undergoing haemodialysis therapy exhibit an increased incidence of whole-body inflammation and other thrombotic events. Similarly, therapeutic cells such as hepatocytes upon implantation initiate an instant blood mediated inflammatory reaction, responsible for cell damage and death via apoptosis.

    In order to achieve safer and more efficient therapeutic interventions,  engineering of materials and cells that can avoid these adverse reactions is essential. Fabrication of biomaterials consisting of  coating of bioinert polymers to avoid immune recognition and activation is a promising approach to modulate immune reactions.

    In this thesis, we have employed a PEG-lipid polymer coating, which intercalates in to biomembranes via hydrophobic interactions and thus shields from immune rejection. Treatment with PEG-lipid not only makes the surface “invisible” to immune cells but it also acts as a filter which prevents entry of immune cells without inducing cytotoxicity. Results from this thesis illustrate that fabrication of bio-surfaces by bio-inert PEG-lipid polymer is a harmless procedure which not  only attenuates thrombo-inflammation but also assist in design of self-tailored materials for a wide range of biomedical applications.

  • Lagercrantz, Bo
    The Nordic Museum.
    Mörnerska porträttsamlingen på Tyresö1958In: Fataburen: Nordiska museets och Skansens årsbok, Stockholm: Nordiska museets förlag, 1958, p. 59-71Chapter in book (Other academic)
  • Hägglund, Patricia
    et al.
    Umeå Univ, Fac Med, Dept Odontol, Oral & Maxillofacial Radiol, Umeå, Sweden.
    Fält, Anna
    Örebro Univ, Sch Med Sci, Clin Epidemiol & Biostat, Örebro, Sweden.
    Hägg, Mary
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centre for Research and Development, Gävleborg. Hudiksvall Hosp, Cty Council Gavleborg, Dept Otorhinolaryngol, Speech & Swallowing Ctr, Hudiksvall, Sweden.
    Wester, Per
    Umeå Univ, Dept Publ Hlth & Clin Med, Umeå, Sweden; Karolinska Inst, Danderyd Hosp, Dept Clin Sci, Stockholm, Sweden.
    Jäghagen, Eva Levring
    Umeå Univ, Fac Med, Dept Odontol, Oral & Maxillofacial Radiol, Umeå, Sweden.
    Swallowing dysfunction as risk factor for undernutrition in older people admitted to Swedish short-term care: a cross-sectional study2019In: Aging Clinical and Experimental Research, ISSN 1594-0667, E-ISSN 1720-8319, Vol. 31, no 1, p. 85-94Article in journal (Refereed)
    Abstract [en]

    Background: Swallowing dysfunction and risk of undernutrition increase the risk of pneumonia, morbidity, and mortality. Short-term care is an unexplored care context, where many older people stay yearly.

    Aim: This cross-sectional study aimed to describe and analyze the relationship between swallowing dysfunction and risk of undernutrition among older people in short-term care, including potential gender-related differences.

    Methods: In total, 391 people (209 women), aged ≥ 65 years (median age 84 years) and admitted to short-term care in five Swedish counties participated. They went through a timed water swallow test to assess swallowing dysfunction, including abnormal swallowing capacity and signs of aspiration (i.e., cough and voice change). Risk for undernutrition was assessed using the Minimal Eating Observation and Nutrition Form-version II.

    Results´: Swallowing dysfunction was observed in 248 of 385 (63%) participants, including abnormal swallowing capacity in 213 of 385 (55%) and aspiration signs in 127 of 377 (34%). Abnormal swallowing capacity was more frequent among women (p = 0.030), whereas men with normal swallowing capacity exhibited signs of aspiration more frequently (cough p = 0.038, voice change p = 0.004). Risk of undernutrition was found in 91 of 390 (23%) participants, more frequently among women (p = 0.007). A logistic regression model revealed an increased risk of undernutrition among older people with abnormal swallowing capacity (OR 1.74, 95% CI 1.04–2.92, p = 0.034).

    Conclusions: The high prevalence of swallowing dysfunction and risk of undernutrition highlight the need for a systematic screening program and feasible treatment to improve swallowing function for adequate and safe food intake among older people in short-term care.

    Clinical trial registration: This study was registered with ClinicalTrials.gov on July 4, 2016, under NCT02825927.

  • Li, Congdong
    et al.
    School of Management, Jinan University, Guangzhou, 510632, China / College of Management and Economics, Tianjin University, Tianjin, 300072, China.
    Zhang, Fanshun
    School of Management, Jinan University, Guangzhou, 510632, China.
    Cao, Cejun
    Institute of Physical Internet, School of Electrical and Information Engineering, Jinan University (Zhuhai Campus), Zhuhai, 519070, China / College of Management and Economics, Tianjin University, Tianjin, 300072, China.
    Liu, Yang
    Linköping University, Department of Management and Engineering, Environmental Technology and Management. Linköping University, Faculty of Science & Engineering. Institute of Physical Internet, School of Electrical and Information Engineering, Jinan University (Zhuhai Campus), Zhuhai, 519070, China / Department of Production, University of Vaasa, 65200 Vaasa, Finland.
    Qu, Ting
    Institute of Physical Internet, School of Electrical and Information Engineering, Jinan University (Zhuhai Campus), Zhuhai, 519070, China.
    Organizational coordination in sustainable humanitarian supply chain: an evolutionary game approach2019In: Journal of Cleaner Production, ISSN 0959-6526, E-ISSN 1879-1786, Vol. 219, p. 291-303Article in journal (Refereed)
    Abstract [en]

    Sustainable humanitarian supply chain has a great impact on saving lives, decreasing human suffering and contributing to development. Organizational coordination plays an important role in it, although it is uncommon to be established due to the conflicting interests and expectations. To cope with the problem and achieve the sustainability of humanitarian supply chain, the coordination between private sector and humanitarian organization was further discussed with the help of sustainable principle regarding stakeholder approach. Different from the existing literature that elaborated the drivers and the advantages of coordination, this paper aims to explore the coordination mechanism regarding whether to coordinate, when to adopt the optimal coordinated strategy and how such a strategy can perform well. To analyze the tendency of the coordinated decisions, evolutionary game models concerning traditional and trust mechanisms were developed. Then, computational studies based on hypothetic data were simulated to validate the effectiveness of the proposed model. Results indicated that the coordination decision was affected by coordinated returns and costs, normal returns and extra returns in terms of the traditional mechanism. Several situations in regard to the coordinated decisions were analyzed by adopting evolutionary stable strategies. Moreover, trust had a significantly positive impact on coordination promotion under the support of potential returns and high-level trust. Finally, managerial insights for achieving the sustainable humanitarian supply chain were given from the perspective of organizational coordination and strategy.

  • Henschen-Ingvar, Ingegerd
    The Nordic Museum.
    "Jämväl i Norden"1958In: Fataburen: Nordiska museets och Skansens årsbok, Stockholm: Nordiska museets förlag, 1958, p. 47-58Chapter in book (Other academic)
  • Liedgren, Rut
    The Nordic Museum.
    Severin Nilson som fotograf1958In: Fataburen: Nordiska museets och Skansens årsbok, Stockholm: Nordiska museets förlag, 1958, p. 7-24Chapter in book (Other academic)
  • Östman, Sofi
    et al.
    Umeå University, Faculty of Arts, Department of historical, philosophical and religious studies, Environmental Archaeology Lab.
    Eriksson, Samuel
    Umeå University, Faculty of Arts, Department of historical, philosophical and religious studies, Environmental Archaeology Lab.
    Buckland, Philip
    Umeå University, Faculty of Arts, Department of historical, philosophical and religious studies, Environmental Archaeology Lab.
    Linderholm, Johan
    Umeå University, Faculty of Arts, Department of historical, philosophical and religious studies, Environmental Archaeology Lab.
    Miljöarkeologisk analys av prover från RAÄ 113:1 och Obj.nr 10. Själevadsocken, Örnsköldsvik kommun, Västernorrlands län, Ångermanland2017Report (Other academic)
  • Berg, Gösta
    The Nordic Museum.
    "Skålen som bruktes i tolfte Carls tid": ett dalsländskt minne i Kungl. Livrustkammaren1958In: Fataburen: Nordiska museets och Skansens årsbok, Stockholm: Nordiska museets förlag, 1958, p. 25-46Chapter in book (Other academic)
  • Olsson, Nils
    Byggnadsminnen i sten: en material- och skadeinventering1996 (ed. 1)Book (Other academic)
  • Cars, Göran
    et al.
    Olsson, Krister
    Snickars, Folke
    Kulturmiljö på spel: en studie av strategier att bevara och utveckla den byggda miljöns kulturvärden1996 (ed. 1)Book (Other academic)
  • Korolkovas, Airidas
    et al.
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Materials Physics. Inst Laue Langevin, Grenoble, France.
    Prévost, Sylvain
    Inst Laue Langevin, Grenoble, France.
    Kawecki, Maciej
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Materials Physics.
    Devishvili, Anton
    Inst Laue Langevin, Grenoble, France; Lund University, Dept Phys Chem, Lund, Sweden.
    Adlmann, Franz
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Materials Physics.
    Gutfreund, Philipp
    Inst Laue Langevin, Grenoble, France.
    Wolff, Max
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Materials Physics.
    The viscoelastic signature underpinning polymer deformation under shear flow2019In: Soft Matter, ISSN 1744-683X, E-ISSN 1744-6848, Vol. 15, no 3, p. 371-380Article in journal (Refereed)
    Abstract [en]

    Entangled polymers are deformed by a strong shear flow. The shape of the polymer, called the form factor, is measured by small angle neutron scattering. However, the real-space molecular structure is not directly available from the reciprocal-space data, due to the phase problem. Instead, the data has to be fitted with a theoretical model of the molecule. We approximate the unknown structure using piecewise straight segments, from which we derive an analytical form factor. We fit it to our data on a semi-dilute entangled polystyrene solution under in situ shear flow. The character of the deformation is shown to lie between that of a single ideal chain (viscous) and a cross-linked network (elastic rubber). Furthermore, we use the fitted structure to estimate the mechanical stress, and find a fairly good agreement with rheology literature.

  • Gullman, Jan (Contributor)
    Törnblom, Mille (Contributor)
    Konserveringstekniska studier. Principles of bronze sculpture: its making and unmaking : a study of outdoor bronze sculpture conse...1994Book (Other academic)
  • Mattsson, Einar
    Konserveringstekniska studier.: Deterioration of archaeological material in soil : results on bronze artefacts1996 (ed. 1)Book (Other academic)
  • Östlund, Ulrika
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centre for Research and Development, Gävleborg. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Caring Sciences.
    Blomberg, Karin
    Örebro Univ, Sch Hlth Sci, Fac Med & Hlth, Örebro, Sweden.
    Söderman, Annika
    Örebro Univ, Sch Hlth Sci, Fac Med & Hlth, Örebro, Sweden.
    Harstäde, Carina Werkander
    Linnaeus Univ, Dept Hlth & Caring Sci, Ctr Collaborat Palliat Care, Kalmar Vaxjö, Sweden.
    How to conserve dignity in palliative care: suggestions from older patients, significant others, and healthcare professionals in Swedish municipal care2019In: BMC Palliative Care, ISSN 1472-684X, E-ISSN 1472-684X, Vol. 18, article id 10Article in journal (Refereed)
    Abstract [en]

    Background: An essential aspect of palliative care nursing is to conserve the dignity of the patient. A Dignity Care Intervention (DCI) has been developed in Scotland to facilitate this role for nurses. The DCI is now being adapted to a Swedish context (DCI-SWE) and a central step is to identify culturally relevant, dignity-conserving care actions. These care actions will be incorporated into the DCI-SWE. Therefore, the aim of this study was to suggest care actions for conserving dignity in palliative care from the perspectives of the patients, significant others (SOs), and health care professionals (HPs) in municipality care in Sweden.

    Methods: This study used a descriptive design with a qualitative approach. Data from 20 participants were collected through semi-structured individual interviews with patients (n = 3), SOs (n = 4), two focus groups with nurses (n = 9) and one focus group with physicians (n = 4) in two Swedish municipalities. These data were deductively analysed using qualitative content analysis with the Chochinov model of dignity as framework.

    Results: With the Chochinov model of dignity as a framework, care actions based on suggestions from the participants were identified and presented under three themes: Illness related concerns, Dignity conserving repertoire, and Social dignity inventory. The study found both specific concrete care actions and more general approaches. Such general approaches were found to be relevant for several dignity related issues as all-embracing attitudes and behaviours. However, these general approaches could also be relevant as specific care actions to conserve dignity in relation to certain issues. Care actions were also found to be linked to each other, showing the importance of a holistic perspective in conserving dignity.

    Conclusions: As part of the adaption of the DCI from a Scottish to a Swedish context, this study added relevant care actions for collaborative planning of individualised care in mutual dialogues between nurses and those they care for. The adapted intervention, DCI-SWE, has the potential to help the nurses in providing palliative care of evidence-based quality.

  • Levin, Lena
    Swedish National Road and Transport Research Institute, Society, environment and transport, Mobility, actors and planning processes.
    Analys av integreringen av jämställdhet i regional transportplanering i Dalarna: Regional systemanalys Dalarna och Länsplan för regional transportinfrastruktur Dalarna 2018–20292019Report (Other academic)
    Abstract [en]

    The aim of the study, which is reported in this publication, was to analyse the integration of the transport policy’s equality objective in the regional transport planning in Dalarna. The project was carried out based on qualitative content analysis of the two documents "Regional system analysis Dalarna - basis for transport infrastructure planning" and "County plan for regional transport infrastructure Dalarna 2018–2029" and interviews with eight key persons who participated in the work processes in developing the two documents. The documents show a good picture of the transport infrastructure in the region, but a quite general picture of the population – there is some statistics but no distribution between different population groups. The researchers suggest that the knowledge that exists about the transport infrastructure and the population regionally, should be used more systematically to analyse different groups (such as women and men, older and younger) as transport users, their power of the transport system and their opportunities to influence their own mobility. It appears from the interviews that both gender equality and diversity mainstreaming are perceived as difficult in regional transport planning and that more knowledge and experience are needed. It is pointed out that there is some knowledge but that there are no structures for how it can be incorporated into the planning process. Some statements indicate that pioneering work is ongoing. Gender equality and diversity are described by some as "new" elements in regional transport infrastructure planning, compared to issues such as accessibility, growth and the environment. Interviewees said they lacked developed routines for integrating gender equality and diversity into their work processes. Regarding gender equality a clearer focus is required – for example, to integrate gender-disaggregated statistics at regional level and analyses of the region linked to the target formulations at national level (the transport policy and the national gender equality goals). An example of a method could be gender equality impact assessment (GIA), but also a broader social impact assessment (SIA) where different groups are included based on the Discrimination Act.

  • Friberg, Gunnel (Contributor)
    Natursten i byggnader. Malmöhus och Kristianstads län1994 (ed. 1)Book (Other academic)
  • Dunér, Marianne
    et al.
    Rosander, Eva
    Tulin, Olle
    Skyltar för svenska kulturmiljöer1996 (ed. 1)Book (Other academic)
  • Ersgård, Lars
    et al.
    Hållans Stenholm, Ann-Mari
    Medeltida landsbygd: en arkeologisk utvärdering : forskningsöversikt, problemområden, katalog1996Book (Other academic)
  • Olofsson, Malin
    et al.
    Robertson, Elizabeth K.
    Edler, Lars
    Arneborg, Lars
    SMHI, Research Department, Oceanography.
    Whitehouse, Martin J.
    Ploug, Helle
    Nitrate and ammonium fluxes to diatoms and dinoflagellates at a single cell level in mixed field communities in the sea2019In: Scientific Reports, ISSN 2045-2322, E-ISSN 2045-2322, Vol. 9, article id 1424Article in journal (Refereed)
  • Olsson, Marianne
    The Nordic Museum.
    Båtbygge vid Mälaren1958In: Fataburen: Nordiska museets och Skansens årsbok, Stockholm: Nordiska museets förlag, 1958, p. 191-195Chapter in book (Other academic)
  • Abtahi, Jahan
    et al.
    Linköping University, Department of Clinical and Experimental Medicine, Division of Surgery, Orthopedics and Oncology. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Maxillofacial Unit.
    Malakuti, Iman
    Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Maxillofacial Unit.
    Ajan, Aida
    Linköping University, Department of Clinical and Experimental Medicine, Division of Surgery, Orthopedics and Oncology. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Maxillofacial Unit.
    Surgical Management of Granular Cell Tumor of the Orbit: Case Report and Literature Review2019In: The Open Dentistry Journal, p. 33-40Article in journal (Refereed)
    Abstract [en]

    Introduction: Granular Cell Tumors (GCTs) of the orbit are rare-entity soft-tissue tumors, and few reports have been published in the literature. The treatment of the choice is total excision. Early diagnosis prior to surgery is valuable for the distinction of malignant from benign tumor.

    Case presentation: We report a case of a 55-year-old woman with a solitary slow-growing mass in the right orbit with the involvement of the rectus inferior muscle, and present a review of the recent literature. The lesion had a diameter of 1 cm and was noticed 2 years before the examination. Excisional biopsy confirmed the diagnosis of GCT. The tumor was resected through a retroseptal transconjunctival approach. The final histological examination revealed findings characteristic of GCT, including positive reaction for protein S-100, SOX10, and calcitonin and negative reaction for desmin, myogenin, Smooth Muscle Antigen (SMA), Melan-A, and HMB-45. There were no signs of malignancy in this sample. Disturbance of motility was not noted by the patient after surgery.

    Conclusion: GCT should be included in the differential diagnosis of intraorbital lesions, particularly those that involve the orbit muscles. A biopsy is recommended before surgical resection, to exclude malignancy and prevent radical resection.

  • Ramírez Villegas, Ricardo
    et al.
    Dalarna University, School of Technology and Business Studies, Energy Technology. University of Gävle.
    Eriksson, O.
    Olofsson, T.
    Life cycle assessment of building renovation measures–trade-off between building materials and energy2019In: Energies, ISSN 1996-1073, E-ISSN 1996-1073, Vol. 12, no 3, article id 344Article in journal (Refereed)
  • Abacan, MaryAnn
    et al.
    Univ Philippines Manila, Inst Human Genet, NIH, Manila, Philippines.
    Alsubaie, Lamia
    KASCH, King Abdulaziz Med City, Riyadh, Saudi Arabia.
    Barlow-Stewart, Kristine
    Univ Sydney, Fac Med & Hlth, Northern Clin Sch, Sydney, NSW, Australia.
    Caanen, Beppy
    Maastricht Univ, Dept Clin Genet, Med Ctr, Maastricht, Netherlands.
    Cordier, Christophe
    SYNLAB Genet, Dept Genet, Lausanne, Switzerland.
    Courtney, Eliza
    Natl Canc Ctr, Div Med Oncol, Canc Genet Serv, Singapore, Singapore.
    Davoine, Emeline
    Lausanne Univ Hosp CHUV, Lausanne, Switzerland.
    Edwards, Janice
    Univ South Carolina, Genet Counseling Program, Transnat Alliance Genet Counseling, Columbia, SC USA.
    Elackatt, Niby J.
    Cloudnine Hosp, Org Rare Dis India, Bangalore, Karnataka, India.
    Gardiner, Kate
    LifeLabs Genet, Toronto, ON, Canada.
    Guan, Yue
    Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA USA.
    Huang, Lian-Hua
    China Med Univ, Sch Nursing, Taichung, Taiwan;Natl Taiwan Univ, Coll Med, Sch Nursing, Taipei, Taiwan.
    Ingvoldstad, Charlotta
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Lifestyle and rehabilitation in long term illness. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health. Karolinska Univ Hosp, Ctr Fetal Med & Clin Genet, Stockholm, Sweden;Karolinska Inst, Dept Clin Sci Intervent & Technol, Stockholm, Sweden.
    Kejriwal, Sahil
    Univ Washington, Inst Publ Hlth Genet, Seattle, WA USA.
    Kim, Hyon J.
    Ajou Univ, Med Sch, Suwon, South Korea;Konyang Univ, Grad Sch, Suwon, South Korea.
    Lambert, Deborah
    Natl Rare Dis Off, Dublin, Ireland.
    Lantigua-Cruz, Paulina Araceli
    Univ Med Sci Havana, Havana, Cuba.
    Lee, Juliana M. H.
    Natl Univ Malaysia, Kuala Lumpur, Malaysia.
    Lodahl, Marianne
    Copenhagen Univ Hosp, Rigshosp, Dept Clin Genet, Copenhagen, Denmark.
    Lunde, Ashild
    Univ Bergen, Dept Global Publ Hlth & Primary Care, Bergen, Norway.
    Macaulay, Shelley
    Univ Witwatersrand, Fac Hlth Sci, Div Human Genet, Johannesburg, South Africa;Natl Hlth Lab Serv, Johannesburg, South Africa.
    Macciocca, Ivan
    Victorian Clin Genet Serv, Melbourne, Vic, Australia.
    Margarit, Sonia
    Clin Alemana Univ Desarrollo, Fac Med, Ctr Genet & Genom, Santiago, Chile.
    Middleton, Anna
    Soc & Eth Res Connecting Sci, Wellcome Genome Campus, Cambridge, England;Univ Cambridge, Fac Educ, Cambridge, England.
    Moldovan, Ramona
    Babes Bolyai Univ, Dept Psychol, Cluj Napoca, Romania.
    Ngeow, Joanne
    Natl Canc Ctr, Div Med Oncol, Canc Genet Serv, Singapore, Singapore.
    Obregon-Tito, Alexandra J.
    Univ Arkansas Med Sci, Little Rock, AR 72205 USA.
    Ormond, Kelly E.
    Stanford Univ, Sch Med, Dept Genet, Stanford, CA USA;Stanford Univ, Sch Med, Stanford Ctr Biomed Eth, Stanford, CA USA;Stanford Univ, Sch Med, 300 Pasteur Dr,MC 5208, Stanford, CA USA.
    Paneque, Milena
    Univ Porto, CGPP Ctr Predict & Prevent Genet, I3S, Porto, Portugal;Univ Porto, IBMC Inst Mol & Cell Biol, Porto, Portugal.
    Powell, Karen
    Cone Hlth Canc Ctr, Greensboro, NC USA.
    Sanghavi, Kunal
    Jackson Lab Genom Med, Farmington, CT USA.
    Scotcher, Diana
    Manchester Univ Hosp NHS Fdn Trust, St Marys Hosp, Manchester Ctr Genom Med, Manchester, Lancs, England.
    Scott, Jenna
    Univ British Columbia, Vancouver, BC, Canada.
    Juhe, Clara Serra
    Univ Pompeu Fabra, Dept Ciencies Expt & Salut, Inst Hosp Mar Invest Med, Ctr Invest Biomed Red Enfermedades Raras, Barcelona, Spain.
    Shkedi-Rafid, Shiri
    Hadassah Hebrew Univ, Med Ctr, Jerusalem, Israel.
    Wessels, Tina-Marie
    Univ Cape Town, Div Human Genet, Cape Town, South Africa.
    Yoon, Sook-Yee
    Natl Univ Malaysia, Kuala Lumpur, Malaysia;Canc Res, Subang Jaya, Malaysia;Univ Malaya, Med Ctr, Kuala Lumpur, Malaysia.
    Wicklund, Catherine
    Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA.
    The Global State of the Genetic Counseling Profession2019In: European Journal of Human Genetics, ISSN 1018-4813, E-ISSN 1476-5438, Vol. 27, no 2, p. 183-197Article, review/survey (Refereed)
    Abstract [en]

    The profession of genetic counseling (also called genetic counselling in many countries) began nearly 50 years ago in the United States, and has grown internationally in the past 30 years. While there have been many papers describing the profession of genetic counseling in individual countries or regions, data remains incomplete and has been published in diverse journals with limited access. As a result of the 2016 Transnational Alliance of Genetic Counseling (TAGC) conference in Barcelona, Spain, and the 2017 World Congress of Genetic Counselling in the UK, we endeavor to describe as fully as possible the global state of genetic counseling as a profession. We estimate that in 2018 there are nearly 7000 genetic counselors with the profession established or developing in no less than 28 countries.