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  • Widgren, Mats
    Stockholm University, Faculty of Social Sciences, Department of Human Geography.
    Bysamfällighet och tegskifte i Bohuslän 1300-17501997Book (Other academic)
    Abstract [en]

    This is a study in the historical geography of a medieval Norwegian province, based on field evidence, Danish and Norwegian, medieval and early modern sources, and 17th-to-18th century, Swedish cadastral maps. In previous literature, eastern Norway, including Bohuslän, is described as having been characterised by single farms with fields held in severalty. This study shows, however, that concentrated settlements, as well as subdivided fields existed in Bohuslän already in medieval times. The settlement development in Bohuslän, and possibly also in the rest of eastern Norway, must thus be seen as part of general European process, rather than a specifically Norwegian development, isolated from the rest of northern Europe. The specific forms that open fields took can, however be explained by some region-specific factors, among which the rules of inheritance were the most important.

     

  • Webb, Thomas R.
    et al.
    Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.;Glenfield Hosp, NIHR Leicester Cardiovasc Biomed Res Unit, Leicester, Leics, England..
    Erdmann, Jeanette
    Univ Lubeck, Inst Cardiogenet, Lubeck, Germany.;DZHK German Res Ctr Cardiovasc Res, Lubeck, Germany.;Univ Heart Ctr Luebeck, Lubeck, Germany..
    Stirrups, Kathleen E.
    Queen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London, England.;Univ Cambridge, Dept Haematol, Cambridge, England..
    Stitziel, Nathan O.
    Washington Univ, Sch Med, Dept Med, Div Cardiovasc, St Louis, MO 63110 USA.;Washington Univ, Sch Med, Dept Genet, St Louis, MO 63110 USA.;Washington Univ, Sch Med, McDonnell Genome Inst, St Louis, MO USA..
    Masca, Nicholas G. D.
    Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.;Glenfield Hosp, NIHR Leicester Cardiovasc Biomed Res Unit, Leicester, Leics, England..
    Jansen, Henning
    Tech Univ Munich, Deutsch Herzzentrum Munchen, Munich, Germany.;DZHK, Munich, Germany..
    Kanoni, Stavroula
    Queen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London, England..
    Nelson, Christopher P.
    Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.;Glenfield Hosp, NIHR Leicester Cardiovasc Biomed Res Unit, Leicester, Leics, England..
    Ferrario, Paola G.
    DZHK German Res Ctr Cardiovasc Res, Lubeck, Germany.;Univ Lubeck, Inst Med Biometrie & Stat, Lubeck, Germany..
    Koenig, Inke R.
    DZHK German Res Ctr Cardiovasc Res, Lubeck, Germany.;Univ Lubeck, Inst Med Biometrie & Stat, Lubeck, Germany..
    Eicher, John D.
    NHLBI, Ctr Populat Studies, Framingham Heart Study, Framingham, MA USA..
    Johnson, Andrew D.
    NHLBI, Ctr Populat Studies, Framingham Heart Study, Framingham, MA USA..
    Hamby, Stephen E.
    Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.;Glenfield Hosp, NIHR Leicester Cardiovasc Biomed Res Unit, Leicester, Leics, England..
    Betsholtz, Christer
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Immunology, Genetics and Pathology, Vascular Biology. Karolinska Inst, Vasc Biol Unit, Dept Med Biochem & Biophys, Stockholm, Sweden..
    Ruusalepp, Arno
    Univ Tartu, Inst Biomed & Translat Med, Dept Physiol, Tartu, Estonia.;Tartu Univ Hosp, Dept Cardiac Surg, Tartu, Estonia.;Clin Gene Networks AB, Stockholm, Sweden..
    Franzen, Oscar
    Clin Gene Networks AB, Stockholm, Sweden.;Icahn Sch Med Mt Sinai, Inst Genom & Multiscale Biol, Dept Genet & Genom Sci, New York, NY 10029 USA..
    Schadt, Eric E.
    Icahn Sch Med Mt Sinai, Inst Genom & Multiscale Biol, Dept Genet & Genom Sci, New York, NY 10029 USA..
    Bjoerkegren, Johan L. M.
    Karolinska Inst, Vasc Biol Unit, Dept Med Biochem & Biophys, Stockholm, Sweden.;Univ Tartu, Inst Biomed & Translat Med, Dept Physiol, Tartu, Estonia.;Clin Gene Networks AB, Stockholm, Sweden.;Icahn Sch Med Mt Sinai, Inst Genom & Multiscale Biol, Dept Genet & Genom Sci, New York, NY 10029 USA..
    Weeke, Peter E.
    Vanderbilt Univ, Med Ctr, Dept Med, Nashville, TN USA.;Copenhagen Univ Hosp, Rigshosp, Dept Cardiol, Lab Mol Cardiol, Copenhagen, Denmark..
    Auer, Paul L.
    Univ Wisconsin, Sch Publ Hlth, Milwaukee, WI 53201 USA..
    Schick, Ursula M.
    Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA.;Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA..
    Lu, Yingchang
    Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA.;Icahn Sch Med Mt Sinai, Genet Obes & Related Metab Traits Program, New York, NY 10029 USA..
    Zhang, He
    Univ Michigan, Dept Internal Med, Div Cardiovasc Med, Ann Arbor, MI 48109 USA..
    Dube, Marie-Pierre
    Univ Montreal, Fac Med, Dept Med, Montreal, PQ, Canada.;Montreal Heart Inst, Montreal, PQ, Canada..
    Goel, Anuj
    Univ Oxford, Radcliffe Dept Med, Div Cardiovasc Med, Oxford, England.;Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England..
    Farrall, Martin
    Univ Oxford, Radcliffe Dept Med, Div Cardiovasc Med, Oxford, England.;Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England..
    Peloso, Gina M.
    Massachusetts Gen Hosp, Ctr Human Genet Res, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Cardiovasc Res Ctr, Boston, MA 02114 USA.;Harvard Med Sch, Dept Med, Boston, MA USA.;Broad Inst, Program Med & Populat Genet, Cambridge, MA USA..
    Won, Hong-Hee
    Massachusetts Gen Hosp, Ctr Human Genet Res, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Cardiovasc Res Ctr, Boston, MA 02114 USA.;Harvard Med Sch, Dept Med, Boston, MA USA.;Broad Inst, Program Med & Populat Genet, Cambridge, MA USA.;Sungkyunkwan Univ, Samsung Med Ctr, Samsung Adv Inst Hlth Sci & Technol, Seoul, South Korea..
    Do, Ron
    Icahn Sch Med Mt Sinai, Genet Obes & Related Metab Traits Program, New York, NY 10029 USA.;Icahn Sch Med Mt Sinai, Ctr Stat Genet, Dept Genet & Genom Sci, New York, NY 10029 USA.;Icahn Sch Med Mt Sinai, Dept Genet & Genom Sci, Icahn Inst Genom & Multiscale Biol, New York, NY 10029 USA.;Icahn Sch Med Mt Sinai, Zena & Michael Weiner Cardiovasc Inst, New York, NY 10029 USA..
    van Iperen, Erik
    Acad Med Ctr, Dept Biostat, Amsterdam, Netherlands..
    Kruppa, Jochen
    Univ Vet Med Hannover, Inst Anim Breeding & Genet, Hannover, Germany..
    Mahajan, Anubha
    Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England..
    Scott, Robert A.
    Addenbrookes Hosp, MRC Epidemiol Unit, Inst Metab Sci, Cambridge, England..
    Willenborg, Christina
    Univ Lubeck, Inst Cardiogenet, Lubeck, Germany..
    Braund, Peter S.
    Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.;Glenfield Hosp, NIHR Leicester Cardiovasc Biomed Res Unit, Leicester, Leics, England..
    van Capelleveen, Julian C.
    Acad Med Ctr, Dept Vasc Med, Amsterdam, Netherlands..
    Doney, Alex S. F.
    Univ Dundee, Hosp & Med Sch, Med Res Inst, Dundee, Scotland..
    Donnelly, Louise A.
    Univ Dundee, Hosp & Med Sch, Med Res Inst, Dundee, Scotland..
    Asselta, Rosanna
    Humanitas Univ, Dept Biomed Sci, Milan, Italy.;Humanitas Clin & Res Ctr, Milan, Italy..
    Merlini, Pier A.
    Osped Niguarda Ca Granda, Milan, Italy..
    Duga, Stefano
    Humanitas Univ, Dept Biomed Sci, Milan, Italy.;Humanitas Clin & Res Ctr, Milan, Italy..
    Marziliano, Nicola
    Azienda Sanit Locale 3 San Francesco, Nuoro, Italy..
    Denny, Josh C.
    Vanderbilt Univ, Med Ctr, Dept Med, Nashville, TN USA.;Vanderbilt Univ, Med Ctr, Dept Biomed informat, Nashville, TN USA..
    Shaffer, Christian
    Vanderbilt Univ, Med Ctr, Dept Med, Nashville, TN USA..
    El-Mokhtari, Nour Eddine
    Imland Klin Rendsburg, Klin Kardiol Pneumol & Innere Med, Rendsburg, Germany..
    Franke, Andre
    Christian Albrechts Univ Kiel, Inst Clin Mol Biol, Kiel, Germany..
    Heilmann, Stefanie
    Univ Bonn, Inst Human Genet, Bonn, Germany.;Univ Bonn, Dept Genom, Life & Brain Ctr, Bonn, Germany..
    Hengstenberg, Christian
    Washington Univ, Sch Med, McDonnell Genome Inst, St Louis, MO USA.;Tech Univ Munich, Deutsch Herzzentrum Munchen, Munich, Germany..
    Hoffmann, Per
    Univ Bonn, Inst Human Genet, Bonn, Germany.;Univ Bonn, Dept Genom, Life & Brain Ctr, Bonn, Germany.;Univ Basel, Dept Biomed, Div Med Genet, Basel, Switzerland..
    Holmen, Oddgeir L.
    Norwegian Univ Sci & Technol, Dept Publ Hlth & Gen Practice, HUNT Res Ctr, Levanger, Norway.;Trondheim Reg & Univ Hosp, St Olav Hosp, Trondheim, Norway..
    Hveem, Kristian
    Norwegian Univ Sci & Technol, Dept Publ Hlth & Gen Practice, HUNT Res Ctr, Levanger, Norway.;Nord Trondelag Hlth Trust, Levanger Hosp, Dept Med, Levanger, Norway..
    Jansson, Jan-Hakan
    Umea Univ, Res Unit Skelleftea, Dept Publ Hlth & Clin Med, Umea, Sweden..
    Joeckel, Karl-Heinz
    Univ Hosp Essen, Inst Med Informat Biometry & Epidemiol, Essen, Germany..
    Kessler, Thorsten
    Tech Univ Munich, Deutsch Herzzentrum Munchen, Munich, Germany.;DZHK, Munich, Germany..
    Kriebel, Jennifer
    Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Res Unit Mol Epidemiol, Neuherberg, Germany.;Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Epidemiol 2, Neuherberg, Germany.;German Ctr Diabet Res, Neuherberg, Germany..
    Laugwitz, Karl L.
    DZHK, Munich, Germany.;Tech Univ Munich, Klinikum Rechts Isar, Inst Med Klin & Poliklin, Munich, Germany..
    Marouli, Eirini
    Queen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London, England..
    Martinelli, Nicola
    Univ Verona, Sect Internal Med, Dept Med, Verona, Italy..
    McCarthy, Mark I.
    Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England.;Churchill Hosp, Biomed Res Ctr, Oxford Natl Inst Hlth Res, Old Rd Headington, Oxford, England..
    Van Zuydam, Natalie R.
    Univ Oxford, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England..
    Meisinger, Christa
    Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Epidemiol 2, Neuherberg, Germany..
    Esko, Tonu
    Univ Tartu, Estonian Genome Ctr, Tartu, Estonia.;Boston Childrens Hosp, Div Endocrinol, Boston, MA USA.;Harvard Med Sch, Dept Genet, Boston, MA USA.;Broad Inst Massachusetts Inst Technol & Harvard U, Cambridge, MA USA..
    Mihailov, Evelin
    Univ Tartu, Estonian Genome Ctr, Tartu, Estonia..
    Escher, Stefan A.
    Lund Univ, Dept Clin Sci, Ctr Diabet, Genet & Mol Epidemiol Unit, Malmo, Sweden..
    Alver, Maris
    Univ Tartu, Estonian Genome Ctr, Tartu, Estonia.;Inst Mol & Cell Biol, Tartu, Estonia..
    Moebus, Susanne
    Univ Hosp Essen, Inst Med Informat Biometry & Epidemiol, Essen, Germany..
    Morris, Andrew D.
    Univ Edinburgh, Sch Med, Sch Mol Genet & Populat Hlth Sci, Teviot Pl, Edinburgh, Midlothian, Scotland..
    Virtamo, Jarma
    Natl Inst Hlth & Welf THL, Helsinki, Finland..
    Nikpay, Majid
    Univ Ottawa, Inst Heart, Ruddy Canadian Cardiovasc Genet Ctr, Ottawa, ON, Canada..
    Olivieri, Oliviero
    Univ Verona, Sect Internal Med, Dept Med, Verona, Italy..
    Provost, Sylvie
    Montreal Heart Inst, Montreal, PQ, Canada..
    AlQarawi, Alaa
    King Abdulaziz Univ, Princess Al Jawhara Al Brahim Ctr Excellence R, Jeddah, Saudi Arabia..
    Robertson, Neil R.
    Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England..
    Akinsansya, Karen O.
    Merck Sharp & Dohme Ltd, Rahway, NJ USA..
    Reilly, Dermot F.
    Merck Sharp & Dohme Ltd, Rahway, NJ USA..
    Vogt, Thomas F.
    Merck Sharp & Dohme Ltd, Rahway, NJ USA..
    Yin, Wu
    Merck Sharp & Dohme Ltd, Rahway, NJ USA..
    Asselbergs, Folkert W.
    UMC Utrecht, Div Heart & Lungs, Dept Cardiol, Utrecht, Netherlands.;ICIN Netherlands Heart Inst, Durrer Ctr Cardiogenet Res, Utrecht, Netherlands.;UCL, Fac Populat Hlth Sci, Inst Cardiovasc Sci, London, England..
    Kooperberg, Charles
    Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA..
    Jackson, Rebecca D.
    Ohio State Univ, Dept Med, Div Endocrinol Diabet & Metab, Columbus, OH 43210 USA..
    Stahl, Eli
    Icahn Sch Med Mt Sinai, Dept Psychiat, New York, NY 10029 USA..
    Mueller-Nurasyid, Martina
    DZHK, Munich, Germany.;Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Genet Epidemiol, Neuherberg, Germany.;Ludwig Maximilians Univ Munchen, Dept Med 1, Univ Hosp Grosshadern, Munich, Germany..
    Strauch, Konstantin
    Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Genet Epidemiol, Neuherberg, Germany.;Ludwig Maximilians Univ Munchen, Chair Genet Epidemiol, Inst Med Informat Biometry & Epidemiol, Munich, Germany..
    Varga, Tibor V.
    Lund Univ, Dept Clin Sci, Ctr Diabet, Genet & Mol Epidemiol Unit, Malmo, Sweden..
    Waldenberger, Melanie
    Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Res Unit Mol Epidemiol, Neuherberg, Germany.;Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Epidemiol 2, Neuherberg, Germany..
    Zeng, Lingyao
    Tech Univ Munich, Deutsch Herzzentrum Munchen, Munich, Germany.;DZHK, Munich, Germany..
    Chowdhury, Rajiv
    Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England..
    Salomaa, Veikko
    Natl Inst Hlth & Welf THL, Helsinki, Finland..
    Ford, Ian
    Univ Glasgow, Robertson Ctr Biostat, Glasgow, Lanark, Scotland..
    Jukema, J. Wouter
    Leiden Univ, Med Ctr, Leiden & Interuniv Cardiol Inst Netherlands, Dept Cardiol, Utrecht, Netherlands..
    Amouyel, Philippe
    Univ Lille, INSERM, CHU Lille, Inst Pasteur Lille,RID AGE U1167, Lille, France..
    Kontto, Jukka
    Nordestgaard, Borge G.
    Copenhagen Univ Hosp & Med Sci, Copenhagen, Denmark.;Univ Copenhagen, Fac Hlth & Med Sci, Copenhagen, Denmark..
    Ferrieres, Jean
    Toulouse Univ, Sch Med, Toulouse, France..
    Saleheen, Danish
    Univ Penn, Perelman Sch Med, Dept Biostat & Epidemiol, Philadelphia, PA 19104 USA.;Ctr Noncommunicable Dis, Karachi, Pakistan..
    Sattar, Naveed
    Univ Glasgow, Glasgow Cardiovasc Res Ctr, British Heart Fdn, Glasgow, Lanark, Scotland..
    Surendran, Praveen
    Ludwig Maximilians Univ Munchen, Chair Genet Epidemiol, Inst Med Informat Biometry & Epidemiol, Munich, Germany..
    Wagner, Aline
    Univ Strasbourg, Dept Epidemiol & Publ Hlth, Strasbourg, France..
    Young, Robin
    Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England..
    Howson, Joanna M. M.
    Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England..
    Butterworth, Adam S.
    Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England.;Univ Cambridge, Res Unit Donor Hlth & Genom, Natl Inst Hlth Res Blood & Transplant, Cambridge, England..
    Danesh, John
    Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England.;Univ Cambridge, Res Unit Donor Hlth & Genom, Natl Inst Hlth Res Blood & Transplant, Cambridge, England.;Wellcome Trust Sanger Inst, Cambridge, England..
    Ardissino, Diego
    Parma Univ Hosp, Parma, Italy..
    Bottinger, Erwin P.
    Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA..
    Erbel, Raimund
    Univ Hosp Essen, Inst Med Informat Biometry & Epidemiol, Essen, Germany..
    Franks, Paul W.
    Lund Univ, Dept Clin Sci, Ctr Diabet, Genet & Mol Epidemiol Unit, Malmo, Sweden.;Harvard Sch Publ Hlth, Dept Nutr, Boston, MA USA.;Umea Univ, Dept Publ Hlth & Clin Med, Umea, Sweden..
    Girelli, Domenico
    Univ Verona, Sect Internal Med, Dept Med, Verona, Italy..
    Hall, Alistair S.
    Univ Leeds, Leeds Inst Genet Hlth & Therapeut, Leeds, W Yorkshire, England..
    Hovingh, G. Kees
    Acad Med Ctr, Dept Vasc Med, Amsterdam, Netherlands..
    Kastrati, Adnan
    Tech Univ Munich, Deutsch Herzzentrum Munchen, Munich, Germany..
    Lieb, Wolfgang
    Christian Albrechts Univ Kiel, Inst Epidemiol & Biobank Popgen, Kiel, Germany..
    Meitinger, Thomas
    DZHK, Munich, Germany.;Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Human Genet, Neuherberg, Germany.;Tech Univ Munich, Inst Human Genet, Munich, Germany..
    Kraus, William E.
    Duke Univ, Duke Mol Physiol Inst, Durham, NC USA.;Duke Univ, Dept Med, Div Cardiol, Durham, NC USA..
    Shah, Svati H.
    Duke Univ, Duke Mol Physiol Inst, Durham, NC USA.;Duke Univ, Dept Med, Div Cardiol, Durham, NC USA..
    McPherson, Ruth
    Univ Ottawa, Inst Heart, Ruddy Canadian Cardiovasc Genet Ctr, Ottawa, ON, Canada..
    Orho-Melander, Marju
    Lund Univ, Clin Res Ctr, Dept Clin Sci Malmo, Malmo, Sweden..
    Melander, Olle
    Lund Univ, Malmo Univ Hosp, Dept Clin Sci Diabet & Endocrinol, Malmo, Sweden..
    Metspalu, Andres
    Univ Tartu, Estonian Genome Ctr, Tartu, Estonia.;Inst Mol & Cell Biol, Tartu, Estonia..
    Palmer, Colin N. A.
    Univ Dundee, Hosp & Med Sch, Med Res Inst, Dundee, Scotland..
    Peters, Annette
    DZHK, Munich, Germany.;Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Epidemiol 2, Neuherberg, Germany..
    Rader, Daniel J.
    Univ Penn, Dept Genet, Cardiovasc Inst, Philadelphia, PA 19104 USA.;Univ Penn, Inst Translat Med & Therapeut, Perelman Sch Med, Philadelphia, PA 19104 USA..
    Reilly, Muredach P.
    Columbia Univ, Dept Med, Div Cardiol, New York, NY USA.;Columbia Univ, Irving Inst Clin & Translat Res, New York, NY USA..
    Loos, Ruth J. F.
    Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA.;Icahn Sch Med Mt Sinai, Genet Obes & Related Metab Traits Program, New York, NY 10029 USA.;Icahn Sch Med Mt Sinai, Mindich Child Hlth & Dev Inst, New York, NY 10029 USA..
    Reiner, Alex P.
    Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA.;Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA..
    Roden, Dan M.
    Vanderbilt Univ, Med Ctr, Dept Med, Nashville, TN USA.;Vanderbilt Univ, Med Ctr, Dept Pharmacol, Nashville, TN 37232 USA..
    Tardif, Jean-Claude
    Univ Montreal, Fac Med, Dept Med, Montreal, PQ, Canada.;Montreal Heart Inst, Montreal, PQ, Canada..
    Thompson, John R.
    Glenfield Hosp, NIHR Leicester Cardiovasc Biomed Res Unit, Leicester, Leics, England.;Univ Leicester, Dept Hlth Sci, Leicester, Leics, England..
    Wareham, Nicholas J.
    Addenbrookes Hosp, MRC Epidemiol Unit, Inst Metab Sci, Cambridge, England..
    Watkins, Hugh
    Univ Oxford, Radcliffe Dept Med, Div Cardiovasc Med, Oxford, England.;Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England..
    Willer, Cristen J.
    Univ Montreal, Fac Med, Dept Med, Montreal, PQ, Canada.;Univ Michigan, Dept Computat Med & Bioinformat, Ann Arbor, MI 48109 USA.;Univ Michigan, Dept Human Genet, Ann Arbor, MI 48109 USA..
    Samani, Nilesh J.
    Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.;Glenfield Hosp, NIHR Leicester Cardiovasc Biomed Res Unit, Leicester, Leics, England..
    Schunkert, Heribert
    Tech Univ Munich, Deutsch Herzzentrum Munchen, Munich, Germany.;DZHK, Munich, Germany..
    Deloukas, Panos
    Queen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London, England.;King Abdulaziz Univ, Princess Al Jawhara Al Brahim Ctr Excellence R, Jeddah, Saudi Arabia..
    Kathiresan, Sekar
    Massachusetts Gen Hosp, Ctr Human Genet Res, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Cardiovasc Res Ctr, Boston, MA 02114 USA.;Harvard Med Sch, Dept Med, Boston, MA USA.;Massachusetts Gen Hosp, Div Cardiol, Boston, MA 02114 USA..
    Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease2017In: Journal of the American College of Cardiology, ISSN 0735-1097, E-ISSN 1558-3597, Vol. 69, no 7, 823-836 p.Article in journal (Refereed)
    Abstract [en]

    BACKGROUND Genome-wide association studies have so far identified 56 loci associated with risk of coronary artery disease (CAD). Many CAD loci show pleiotropy; that is, they are also associated with other diseases or traits.

    OBJECTIVES This study sought to systematically test if genetic variants identified for non-CAD diseases/traits also associate with CAD and to undertake a comprehensive analysis of the extent of pleiotropy of all CAD loci.

    METHODS In discovery analyses involving 42,335 CAD cases and 78,240 control subjects we tested the association of 29,383 common (minor allele frequency >5%) single nucleotide polymorphisms available on the exome array, which included a substantial proportion of known or suspected single nucleotide polymorphisms associated with common diseases or traits as of 2011. Suggestive association signals were replicated in an additional 30,533 cases and 42,530 control subjects. To evaluate pleiotropy, we tested CAD loci for association with cardiovascular risk factors (lipid traits, blood pressure phenotypes, body mass index, diabetes, and smoking behavior), as well as with other diseases/traits through interrogation of currently available genome-wide association study catalogs.

    RESULTS We identified 6 new loci associated with CAD at genome-wide significance: on 2q37 (KCNJ13-GIGYF2), 6p21 (C2), 11p15 (MRVI1-CTR9), 12q13 (LRP1), 12q24 (SCARB1), and 16q13 (CETP). Risk allele frequencies ranged from 0.15 to 0.86, and odds ratio per copy of the risk allele ranged from 1.04 to 1.09. Of 62 new and known CAD loci, 24 (38.7%) showed statistical association with a traditional cardiovascular risk factor, with some showing multiple associations, and 29 (47%) showed associations at p < 1 x 10(-4) with a range of other diseases/traits.

    CONCLUSIONS We identified 6 loci associated with CAD at genome-wide significance. Several CAD loci show substantial pleiotropy, which may help us understand the mechanisms by which these loci affect CAD risk.

  • Adlitzer, Helena
    et al.
    Regionalt cancercentrum Stockholm Gotland.
    Andershed, Birgitta
    Ersta Sköndal Högskola.
    Axelsson, Bertil
    Östersunds sjukhus; Umeå universitet.
    Blomberg, Karin
    Örebro University, School of Health Sciences.
    Fridegren, Inger
    Nacka Närsjukhus.
    Friedrichsen, Maria
    Palliativt kompetenscentrum Östergötland, Vrinnevisjukhuset; Linköpings Universitet .
    Fürst, Carl-Johan
    Palliativt utvecklingscentrum, Lunds universitet och Region Skåne.
    Heedman, Per-Anders
    Palliativt kompetenscentrum i Östergötland.
    Henoch, Ingela
    Sahlgrenska akademin; Göteborgs universitet.
    Kenne Sarenmalm, Elisabeth
    FoU Centrum, Skaraborgs sjukhus, Skövde.
    Löfdahl, Elisabet
    Palliativa sektionen SU/Sahlgrenska universitetssjukhuset.
    Melin-Johansson, Christina
    Mittuniversitetet.
    Molander, Ulla
    Sahlgrenska Universitetssjukhuset, Göteborg.
    Persson, Hans
    Danderyds sjukhus.
    Pessah-Rasmussen, Hélène
    Skånes Universitetssjukhus (SUS).
    Rasmussen, Birgit H
    Lunds universitet och Region Skåne.
    Schaufelberger, Maria
    Sahlgrenska universitetssjukhuset.
    Seiger Cronfalk, Berit
    Ersta Sköndal Högskola; Karolinska Institutet.
    Silk, Gerd
    Kvalitets- och utvecklingsenheten Region Gotland.
    Strang, Peter
    Karolinska Institutet och Stockholms Sjukhem, Stockholm.
    Strömberg, Anna
    Linköpings universitetssjukhus.
    Tavemark, Sofia
    Örebro kommun.
    Ternestedt, Britt-Marie
    Ersta Sköndal Högskola, Stockholm.
    Wennman-Larsen, Agneta
    Sophiahemmet Högskola; Karolinska Institutet.
    Wikström, Gerhard
    Uppsala Universitet.
    Österlind, Jane
    Ersta Sköndal högskola.
    Palliativ vård i livets slutskede: Nationellt vårdprogram2016Report (Other academic)
  • Deutschmann, Mats
    Umeå universitet, Moderna språk.
    Apologising in British English2003Doctoral thesis, monograph (Other academic)
    Abstract [en]

    The thesis explores the form, function and sociolinguistic distribution of explicit apologies in the spoken part of the British National Corpus. The sub-corpus used for the study comprises a spoken text mass of about five million words and represents dialogue produced by more than 1700 speakers, acting in a number of different conversational settings. More than 3000 examples of apologising are included in the analysis.

    Primarily, the form and function of the apologies are examined in relation to the type of offence leading up to the speech act. Aspects such as the sincerity of the apologies and the use of additional remedial strategies other than explicit apologising are also considered. Variations in the distributions of the different types of apologies found are subsequently investigated for the two independent variables speaker social identity (gender, social class and age) and conversational setting (genre, formality and group size). The effect of the speaker-addressee relationship on the apology rate and the types of apologies produced is also examined.

    In this study, the prototypical apology, a speech act used to remedy a real or perceived offence, is only one of a number of uses of the apology form in the corpus. Other common functions of the form include discourse-managing devices such as request cues for repetition and markers of hesitation, as well as disarming devices uttered before expressing disagreement and controversial opinions.

    Among the speaker social variables investigated, age and social class are particularly important in affecting apologetic behaviour. Young and middle-class speakers favour the use of the apology form. No substantial gender differences in apologising are apparent in the corpus. I have also been able to show that large conversational groups result in frequent use of the form. Finally, analysis of the effects of the speaker-addressee relationship on the use of the speech act shows that, contrary to expectations based on Brown & Levinson’s theory of politeness, it is the powerful who tend to apologise to the powerless rather than vice versa.

    The study implies that formulaic politeness is an important linguistic marker of social class and that its use often involves control of the addressee.

  • Aad, G.
    et al.
    Brenner, Richard
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Buszello, Claus P.
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Ekelöf, Tord
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Ellert, Mattias
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Ferrari, Arnaud
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Isaksson, Charlie
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Madsen, Alexander
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Öhman, Henrik
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Pelikan, Daniel
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Rangel Smith, Camila
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, High Energy Physics.
    Zwalinski, L.
    Measurement of the t(t)over-bar production cross-section using e mu events with b-tagged jets in pp collisions at root s=7 and 8 TeV with the ATLAS detector2016In: European Physical Journal C, ISSN 1434-6044, E-ISSN 1434-6052, Vol. 76, no 11, 642Article in journal (Refereed)
  • Viman, Leif
    Swedish National Road and Transport Research Institute, Infrastructure, Pavement Technology.
    Stickprov vid utförandeentreprenader: jämförelse mellan ”riskytor” och övriga ytor på några vägobjekt2017Report (Other academic)
    Abstract [en]

    The purpose of this project was to evaluate how the homogeneity can be measured and quantified over a section with newly laid asphalt pavement and determine how the properties varies from defined risk areas and other areas. This can be summarized in three different questions:

     Question 1: What methods are available to measure the homogeneity of newly laid asphalt pavements?

     Question 2: How much will the properties of the surface identified as risk areas, compared to other areas, vary over a defined asphalt pavement section?

     Question 3: Are the results from the contractor’s quality control equal to results from “risk areas” or “adjacent areas”?

  • Edvardsson, David
    et al.
    Umeå University, Faculty of Medicine, Department of Nursing. College of Science, Health and Engineering, School of Nursing and Midwifery, La Trobe University, Level 4 Austin Tower, PO Box 5555, Heidelberg 3084, VIC, Australia..
    Sjögren, Karin
    College of Science, Health and Engineering, School of Nursing and Midwifery, La Trobe University, Level 4 Austin Tower, PO Box 5555, Heidelberg 3084, VIC, Australia..
    Lood, Qarin
    College of Science, Health and Engineering, School of Nursing and Midwifery, La Trobe University, Level 4 Austin Tower, PO Box 5555, Heidelberg 3084, VIC, Australia..
    Bergland, Adel
    Kirkevold, Marit
    Sandman, Per-Olof
    Umeå University, Faculty of Medicine, Department of Nursing. Division of Caring Sciences, Depart Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet, Stockholm, Sweden; Department of Health Sciences, University of Technology, Luleå, Sweden.
    A person-centred and thriving-promoting intervention in nursing homes - study protocol for the U-Age nursing home multi-centre, non-equivalent controlled group before-after trial2017In: BMC Geriatrics, ISSN 1471-2318, E-ISSN 1471-2318, Vol. 17, 22Article in journal (Refereed)
    Abstract [en]

    Background: The literature suggests that person-centred care can contribute to quality of life and wellbeing of nursing home residents, relatives and staff. However, there is sparse research evidence on how person-centred care can be operationalised and implemented in practice, and the extent to which it may promote wellbeing and satisfaction. Therefore, the U-Age nursing home study was initiated to deepen the understanding of how to integrate person-centred care into daily practice and to explore the effects and meanings of this.

    Methods: The study aims to evaluate effects and meanings of a person-centred and thriving-promoting intervention in nursing homes through a multi-centre, non-equivalent controlled group before-after trial design. Three nursing homes across three international sites have been allocated to a person-centred and thriving-promoting intervention group, and three nursing homes have been allocated to an inert control group. Staff at intervention sites will participate in a 12-month interactive educational programme that operationalises thriving-promoting and person-centred care three dimensions: 1) Doing a little extra, 2) Developing a caring environment, and 3) Assessing and meeting highly prioritised psychosocial needs. A pedagogical framework will guide the intervention. The primary study endpoints are; residents’ thriving, relatives’ satisfaction with care and staff job satisfaction. Secondary endpoints are; resident, relative and staff experiences of the caring environment, relatives’ experience of visiting their relative and the nursing home, as well as staff stress of conscience and perceived person-centredness of care. Data on study endpoints will be collected pre-intervention, post-intervention, and at a six-month follow up. Interviews will be conducted with relatives and staff to explore experiences and meanings of the intervention.

    Discussion: The study is expected to provide evidence that can inform further research, policy and practice development on if and how person-centred care may improve wellbeing, thriving and satisfaction for people who reside in, visit or work in nursing homes. The combination of quantitative and qualitative data will illuminate the operationalisation, effects and meaning of person-centred and thriving-promoting care.

  • Blom, Eva Henje
    et al.
    Umeå University, Faculty of Medicine, Department of Clinical Sciences. Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Psychiatry, Division of Child and Adolescent Psychiatry, UCSF Weill Institute for Neurosciences, University of California San Francisco (UCSF), San Francisco, CA, USA.
    Tymofiyeva, Olga
    Chesney, Margaret A.
    Ho, Tiffany C.
    Moran, Patricia
    Connolly, Colm G.
    Duncan, Larissa G.
    Baldini, Lisa
    Weng, Helen Y.
    Acree, Michael
    Goldman, Veronica
    Hecht, Frederick M.
    Yang, Tony T.
    Feasibility and Preliminary Efficacy of a Novel RDoC-Based Treatment Program for Adolescent Depression: "Training for Awareness Resilience and Action" (TARA)-A Pilot Study2017In: Frontiers in Psychiatry, ISSN 1664-0640, E-ISSN 1664-0640, Vol. 7, 208Article in journal (Refereed)
    Abstract [en]

    Background: The novel group treatment program Training for Awareness, Resilience, and Action (TARA) was developed to target specific mechanisms based on neuroscience findings in adolescent depression and framed within the National Institute of Mental Health Research Domain Criteria. TARA contains training of autonomic and emotional self-regulation, interoceptive awareness, relational skills, and value-based committed action.

    Methods: We performed a single-arm trial to test the feasibility and preliminary efficacy of TARA in reducing depression and anxiety levels and assessed whether the specific targeted domains of function reflected the hypothesized symptom change. Twenty-six adolescents (14–18 years old, 7 males and 19 females) participated in the 12-week group program. Assessment was performed before (T0), immediately after (T1), and 3 months after the end of TARA (T2).

    Results: Significant improvement was seen in depression symptoms (Reynolds Adolescent Depression Scale Second Edition) between T0–T1 (t-value = −3.56, p = 0.002, CI = −6.64, −1.77) and T0–T2 (t-value = −4.17, p < 0.001, CI = −11.20, −3.75) and anxiety symptoms (Multidimensional Anxiety Scale for Children) between T0–T1 (t-value = −2.26, p = 0.033, CI = −4.61, −0.21) and T0–T2 (t-value = −3.06, p = 0.006, 95% confidence interval = −9.02, −1.73). Significant improvements in psychological flexibility, sleep, and mindfulness skills were also found between T0 and T2.

    Limitations: The sample size was small without a control condition. The pilot design did not allow for testing the hypothesized brain changes and effect of TARA on relevant systemic biomarkers.

    Conclusion: TARA is feasible in a sample of clinically depressed and/or anxious adolescents and preliminary efficacy was demonstrated by reduced depression and anxiety symptoms. The specific symptom and behavioral outcomes corresponded well with the hypothesized mechanisms of change.

  • Backlund, Anders
    Södertörn University, School of Social Sciences, Political Science.
    Isolation and Policy Co-Optation: The Path Dependency of the Swedish Cordon Sanitaire2016Conference paper (Other academic)
    Abstract [en]

    As populist radical right parties have become electorally successful throughout Europe, mainstream parties have been adopting more restrictive immigration policies in order to win back voters, in what has been labelled a "contagion of the right". Sweden, however, has been a deviant case both in a comparative European context and in relation to influential theories of party competition. Despite the electoral threat from a growing radical right party (the Sweden Democrats) during the last decade, no other party engaged in any significant policy co-optation prior to the 2014 elections. In this paper I consider multiple explanations for this deviance derived from empirical and theoretical literature and mapped onto an analytical framework distinguishing between the party goals policy, office, and votes. The empirical material consists of survey data, statements from party representatives, and parliamentary voting patterns. I find the goal-oriented explanations to be only partially satisfactory, and go on to explore the possibility that the deviance can be explained by the institutionalisation of the Swedish cordon sanitaire – the commitment by all other parties to politically isolate the Sweden Democrats. The path dependency of the cordon sanitaire, I argue, became a behavioural constraint that effectively hindered parties from legitimately engaging in the co-optation of SD policies, until it was removed by the external shock of the 2015 "refugee crisis".

  • Linde, Peter
    Blekinge Institute of Technology, The Library.
    BTH Newsletter on Science Publishing and Information about research funding: March 20172017Other (Other (popular science, discussion, etc.))
  • Jeworrek, Julia
    et al.
    Wu, Lichuan
    Dieterich, Christian
    SMHI, Research Department, Oceanography.
    Rutgersson, Anna
    SMHI, Research Department, Climate research - Rossby Centre.
    Characteristics of convective snow bands along the Swedish east coast2017In: Earth System Dynamics, ISSN 2190-4979, E-ISSN 2190-4987, Vol. 8, 163-175 p.Article in journal (Refereed)
  • Boone, Aaron
    et al.
    Samuelsson, Patrick
    SMHI, Research Department, Climate research - Rossby Centre.
    Gollvik, Stefan
    SMHI, Research Department, Meteorology.
    Napoly, Adrien
    Jarlan, Lionel
    Brun, Eric
    Decharme, Bertrand
    The interactions between soil-biosphere-atmosphere land surface model with a multi-energy balance (ISBA-MEB) option in SURFEXv8-Part 1: Model description2017In: Geoscientific Model Development, ISSN 1991-959X, E-ISSN 1991-9603, Vol. 10, no 2, 843-872 p.Article in journal (Refereed)
  • Bartolino, Valerio
    et al.
    Tian, Huidong
    Bergstrom, Ulf
    Jounela, Pekka
    Aro, Eero
    Dieterich, Christian
    SMHI, Research Department, Oceanography.
    Meier, Markus
    SMHI, Research Department, Oceanography.
    Cardinale, Massimiliano
    Bland, Barbara
    Casini, Michele
    Spatio-temporal dynamics of a fish predator: Density-dependent and hydrographic effects on Baltic Sea cod population2017In: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 12, no 2, e0172004Article in journal (Refereed)
  • Gisselman, Fredrik
    et al.
    Cole, Scott
    Blanck, Josefin
    Kniivilä, Matleena
    Hansen, Nora Skjeerna
    Fornbacke, Elin
    Economic values from the natural and cultural heritage in the Nordic countries: Improving visibility and integrating natural and cultural resource values in Nordic countries2017Book (Other academic)
    Abstract [en]

    Natural and cultural heritage represent key assets that deliver different kind of benefits to citizens in the Nordic countries. This report illustrates the economic values at stake and discusses the important and inevitable key trade-offs facing decision-makers charged with managing these assests.The report has three goals: to briefly describe existing conservation measures in the Nordic countries, to illustrate the type and magnitude of economic values generated by these measures, and to discuss key trade-offs and policy implications arising from the selection of measures, which lead to welfare impacts depending on the level of human use.The valuation studies reviewed in the report demonstrate real economic values associated with the experiences that natural and cultural heritage provides both in terms of increased welfare and regional economic impacts.

  • Public defence: 2017-04-21 13:00 sal FA32, AlbaNova universitetscentrum, Stockholm
    Geng, Ting
    Stockholm University, Faculty of Science, Department of Physics.
    Excited-state dynamics of small organic molecules studied by time-resolved photoelectron spectroscopy2017Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    Ultra-violet and visible light induced processes in small organic molecules play very important roles in many fields, e.g., environmental sciences, biology, material development, chemistry, astrophysics and many others. Thus it is of great importance to better understand the mechanisms behind these processes. To achieve this, a bottom-up approach is most effective, where the photo-induced dynamics occurring in the simplest organic molecule (ethylene) are used as a starting point. Simple substituents and functional groups are added in a controlled manner to ethylene, and changes in the dynamics are investigated as a function of these modifications. In this manner, the dynamics occurring in more complex systems can be explored from a known base.

    In this thesis, the excited state dynamics of small organic molecules are studied by a combination of time-resolved photoelectron spectroscopy and various computational methods in order to determine the basic rules necessary to help understand and predict the dynamics of photo-induced processes.

    The dynamics occurring in ethylene involve a double bond torsion on the ππ* excited state, followed by the decay to the ground state coupled with pyramidalization and hydrogen migration. Several different routes of chemical modification are used as the basis to probe these dynamics as the molecular complexity is increased. (i) When ethylene is modified by the addition of an alkoxyl group (-OCnH2n+1), a new bond cleavage reaction is observed on the πσ* state. When modified by a cyano (-CN) group, a significant change in the carbon atom involved in pyramidalization is observed. (ii) When ethylene used to build up small cyclic polyenes, it is observed that the motifs of the ethylene dynamics persist, expressed as ring puckering and ring opening. (iii) In small heteroaromatic systems, i.e., an aromatic ring containing an ethylene-like sub-structure and one or two non-carbon atoms, the type of heteroatom (N: pyrrole, pyrazole O: furan) gives rise to different bond cleavage and ring puckering channels. Furthermore, adding an aldehyde group (-C=O) onto furan, as a way to lengthen the delocalised ring electron system, opens up additional reaction channels via a nπ* state.

    The results presented here are used to build up a more complete picture of the dynamics that occur in small molecular systems after they are excited by a visible or UV photon, and are used as a basis to motivate further investigations.

  • Zhou, Bin
    et al.
    Bentham, James
    Di Cesare, Mariachiara
    Bixby, Honor
    Danaei, Goodarz
    Cowan, Melanie J.
    Paciorek, Christopher J.
    Singh, Gitanjali
    Hajifathalian, Kaveh
    Bennett, James E.
    Taddei, Cristina
    Bilano, Ver
    Carrillo-Larco, Rodrigo M.
    Djalalinia, Shirin
    Khatibzadeh, Shahab
    Lugero, Charles
    Peykari, Niloofar
    Zhang, Wan Zhu
    Lu, Yuan
    Stevens, Gretchen A.
    Riley, Leanne M.
    Bovet, Pascal
    Elliott, Paul
    Gu, Dongfeng
    Ikeda, Nayu
    Jackson, Rod T.
    Joffres, Michel
    Kengne, Andre Pascal
    Laatikainen, Tiina
    Lam, Tai Hing
    Laxmaiah, Avula
    Liu, Jing
    Miranda, J. Jaime
    Mondo, Charles K.
    Neuhauser, Hannelore K.
    Sundstrom, Johan
    Smeeth, Liam
    Soric, Maroje
    Woodward, Mark
    Ezzati, Majid
    Abarca-Gomez, Leandra
    Abdeen, Ziad A.
    Rahim, Hanan Abdul
    Abu-Rmeileh, Niveen M.
    Acosta-Cazares, Benjamin
    Adams, Robert
    Aekplakorn, Wichai
    Afsana, Kaosar
    Aguilar-Salinas, Carlos A.
    Agyemang, Charles
    Ahmadvand, Alireza
    Ahrens, Wolfgang
    Al Raddadi, Rajaa
    Al Woyatan, Rihab
    Ali, Mohamed M.
    Alkerwi, Ala'a
    Aly, Eman
    Amouyel, Philippe
    Amuzu, Antoinette
    Andersen, Lars Bo
    Anderssen, Sigmund A.
    Angquist, Lars
    Anjana, Ranjit Mohan
    Ansong, Daniel
    Aounallah-Skhiri, Hajer
    Araujo, Joana
    Ariansen, Inger
    Aris, Tahir
    Arlappa, Nimmathota
    Aryal, Krishna
    Arveiler, Dominique
    Assah, Felix K.
    Assuncao, Maria Cecilia F.
    Avdicova, Maria
    Azevedo, Ana
    Azizi, Fereidoun
    Babu, Bontha V.
    Bahijri, Suhad
    Balakrishna, Nagalla
    Bandosz, Piotr
    Banegas, Jose R.
    Barbagallo, Carlo M.
    Barcelo, Alberto
    Barkat, Amina
    Barros, Aluisio J. D.
    Barros, Mauro V.
    Bata, Iqbal
    Batieha, Anwar M.
    Baur, Louise A.
    Beaglehole, Robert
    Ben Romdhane, Habiba
    Benet, Mikhail
    Benson, Lowell S.
    Bernabe-Ortiz, Antonio
    Bernotiene, Gailute
    Bettiol, Heloisa
    Bhagyalaxmi, Aroor
    Bharadwaj, Sumit
    Bhargava, Santosh K.
    Bi, Yufang
    Bikbov, Mukharram
    Bjerregaard, Peter
    Bjertness, Espen
    Bjokelund, Cecilia
    Blokstra, Anneke
    Bo, Simona
    Bobak, Martin
    Boeing, Heiner
    Boggia, Jose G.
    Boissonnet, Carlos P.
    Bongard, Vanina
    Braeckman, Lutgart
    Brajkovich, Imperia
    Branca, Francesco
    Breckenkamp, Juergen
    Brenner, Hermann
    Brewster, Lizzy M.
    Bruno, Graziella
    Bueno-de-Mesquita, H. B. (as)
    Bugge, Anna
    Burns, Con
    Bursztyn, Michael
    de Leon, Antonio Cabrera
    Cameron, Christine
    Can, Gunay
    Candido, Ana Paula C.
    Capuano, Vincenzo
    Cardoso, Viviane C.
    Carlsson, Axel C.
    Carvalho, Maria J.
    Casanueva, Felipe F.
    Casas, Juan-Pablo
    Caserta, Carmelo A.
    Chamukuttan, Snehalatha
    Chan, Angelique W.
    Chan, Queenie
    Chaturvedi, Himanshu K.
    Chaturvedi, Nishi
    Chen, Chien-Jen
    Chen, Fangfang
    Chen, Huashuai
    Chen, Shuohua
    Chen, Zhengming
    Cheng, Ching-Yu
    Dekkaki, Imane Cherkaoui
    Chetrit, Angela
    Chiolero, Arnaud
    Chiou, Shu-Ti
    Chirita-Emandi, Adela
    Cho, Belong
    Cho, Yumi
    Chudek, Jerzy
    Cifkova, Renata
    Claessens, Frank
    Clays, Els
    Concin, Hans
    Cooper, Cyrus
    Cooper, Rachel
    Coppinger, Tara C.
    Costanzo, Simona
    Cottel, Dominique
    Cowell, Chris
    Craig, Cora L.
    Crujeiras, Ana B.
    Cruz, Juan J.
    D'Arrigo, Graziella
    d'Orsi, Eleonora
    Dallongeville, Jean
    Damasceno, Albertino
    Dankner, Rachel
    Dantoft, Thomas M.
    Dauchet, Luc
    De Backer, Guy
    de Gaetano, Giovanni
    De Henauw, Stefaan
    De Smedt, Delphine
    Deepa, Mohan
    Dehghan, Abbas
    Delisle, Helene
    Deschamps, Valerie
    Dhana, Klodian
    Di Castelnuovo, Augusto F.
    Dias-da-Costa, Juvenal Soares
    Diaz, Alejandro
    Dickerson, Ty T.
    Do, Ha T. P.
    Dobson, Annette J.
    Donfrancesco, Chiara
    Donoso, Silvana P.
    Doering, Angela
    Doua, Kouamelan
    Drygas, Wojciech
    Dulskiene, Virginija
    Dzakula, Aleksandar
    Dzerve, Vilnis
    Dziankowska-Zaborszczyk, Elzbieta
    Eggertsen, Robert
    Ekelund, Ulf
    El Ati, Jalila
    Ellert, Ute
    Elosua, Roberto
    Erasmus, Rajiv T.
    Erem, Cihangir
    Eriksen, Louise
    Escobedo-de la Pena, Jorge
    Evans, Alun
    Faeh, David
    Fall, Caroline H.
    Farzadfar, Farshad
    Felix-Redondo, Francisco J.
    Ferguson, Trevor S.
    Fernandez-Berges, Daniel
    Ferrante, Daniel
    Ferrari, Marika
    Ferreccio, Catterina
    Ferrieres, Jean
    Finn, Joseph D.
    Fischer, Krista
    Foeger, Bernhard
    Foo, Leng Huat
    Forslund, Ann-Sofie
    Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences.
    Forsner, Maria
    Fortmann, Stephen P.
    Fouad, Heba M.
    Francis, Damian K.
    Franco, Maria do Carmo
    Franco, Oscar H.
    Frontera, Guillermo
    Fuchs, Flavio D.
    Fuchs, Sandra C.
    Fujita, Yuki
    Furusawa, Takuro
    Gaciong, Zbigniew
    Gareta, Dickman
    Garnett, Sarah P.
    Gaspoz, Jean-Michel
    Gasull, Magda
    Gates, Louise
    Gavrila, Diana
    Geleijnse, Johanna M.
    Ghasemian, Anoosheh
    Ghimire, Anup
    Giampaoli, Simona
    Gianfagna, Francesco
    Giovannelli, Jonathan
    Goldsmith, Rebecca A.
    Goncalves, Helen
    Gonzalez Gross, Marcela
    Gonzalez Rivas, Juan P.
    Gottrand, Frederic
    Graff-Iversen, Sidsel
    Grafnetter, Dusan
    Grajda, Aneta
    Gregor, Ronald D.
    Grodzicki, Tomasz
    Grontved, Anders
    Gruden, Grabriella
    Grujic, Vera
    Guan, Ong Peng
    Gudnason, Vilmundur
    Guerrero, Ramiro
    Guessous, Idris
    Guimaraes, Andre L.
    Gulliford, Martin C.
    Gunnlaugsdottir, Johanna
    Gunter, Marc
    Gupta, Prakash C.
    Gureje, Oye
    Gurzkowska, Beata
    Gutierrez, Laura
    Gutzwiller, Felix
    Hadaegh, Farzad
    Halkjaer, Jytte
    Hambleton, Ian R.
    Hardy, Rebecca
    Harikumar, Rachakulla
    Hata, Jun
    Hayes, Alison J.
    He, Jiang
    Hendriks, Marleen Elisabeth
    Henriques, Ana
    Hernandez Cadena, Leticia
    Herqutanto,
    Herrala, Sauli
    Heshmat, Ramin
    Hihtaniemi, Ilpo Tapani
    Ho, Sai Yin
    Ho, Suzanne C.
    Hobbs, Michael
    Hofman, Albert
    Dinc, Gonul Horasan
    Hormiga, Claudia M.
    Horta, Bernardo L.
    Houti, Leila
    Howitt, Christina
    Htay, Thein Thein
    Htet, Aung Soe
    Hu, Yonghua
    Maria Huerta, Jose
    Husseini, Abdullatif S.
    Huybrechts, Inge
    Hwalla, Nahla
    Iacoviello, Licia
    Iannone, Anna G.
    Ibrahim, M. Mohsen
    Ikram, M. Arfan
    Irazola, Vilma E.
    Islam, Muhammad
    Ivkovic, Vanja
    Iwasaki, Masanori
    Jacobs, Jeremy M.
    Jafar, Tazeen
    Jamrozik, Konrad
    Janszky, Imre
    Jasienska, Grazyna
    Jelakovic, Bojan
    Jiang, Chao Qiang
    Johansson, Mattias
    Jonas, Jost B.
    Jorgensen, Torben
    Joshi, Pradeep
    Juolevi, Anne
    Jurak, Gregor
    Juresa, Vesna
    Kaaks, Rudolf
    Kafatos, Anthony
    Kalter-Leibovici, Ofra
    Kamaruddin, Nor Azmi
    Kasaeian, Amir
    Katz, Joanne
    Kauhanen, Jussi
    Kaur, Prabhdeep
    Kavousi, Maryam
    Kazakbaeva, Gyulli
    Keil, Ulrich
    Boker, Lital Keinan
    Keinanen-Kiukaanniemi, Sirkka
    Kelishadi, Roya
    Kemper, Han C. G.
    Kersting, Mathilde
    Key, Timothy
    Khader, Yousef Saleh
    Khalili, Davood
    Khang, Young-Ho
    Khaw, Kay-Tee
    Kiechl, Stefan
    Killewo, Japhet
    Kim, Jeongseon
    Klumbiene, Jurate
    Kolle, Elin
    Kolsteren, Patrick
    Korrovits, Paul
    Koskinen, Seppo
    Kouda, Katsuyasu
    Koziel, Slawomir
    Kristensen, Peter Lund
    Krokstad, Steinar
    Kromhout, Daan
    Kruger, Herculina S.
    Kubinova, Ruzena
    Kuciene, Renata
    Kuh, Diana
    Kujala, Urho M.
    Kula, Krzysztof
    Kulaga, Zbigniew
    Kumar, R. Krishna
    Kurjata, Pawel
    Kusuma, Yadlapalli S.
    Kuulasmaa, Kari
    Kyobutungi, Catherine
    Lachat, Carl
    Landrove, Orlando
    Lanska, Vera
    Lappas, Georg
    Larijani, Bagher
    Laugsand, Lars E.
    Bao, Khanh Le Nguyen
    Le, Tuyen D.
    Leclercq, Catherine
    Lee, Jeannette
    Lee, Jeonghee
    Lehtimaki, Terho
    Lekhraj, Rampal
    Leon-Munoz, Luz M.
    Levitt, Naomi S.
    Li, Yanping
    Lilly, Christa L.
    Lim, Wei-Yen
    Fernanda Lima-Costa, M.
    Lin, Hsien-Ho
    Lin, Xu
    Linneberg, Allan
    Lissner, Lauren
    Litwin, Mieczyslaw
    Lorbeer, Roberto
    Lotufo, Paulo A.
    Eugenio Lozano, Jose
    Luksiene, Dalia
    Lundqvist, Annamari
    Lunet, Nuno
    Lytsy, Per
    Ma, Guansheng
    Ma, Jun
    Machado-Coelho, George L. L.
    Machi, Suka
    Maggi, Stefania
    Magliano, Dianna J.
    Majer, Marjeta
    Makdisse, Marcia
    Malekzadeh, Reza
    Malhotra, Rahul
    Rao, Kodavanti Mallikharjuna
    Malyutina, Sofia
    Manios, Yannis
    Mann, Jim I.
    Manzato, Enzo
    Margozzini, Paula
    Marques-Vidal, Pedro
    Marrugat, Jaume
    Martorell, Reynaldo
    Mathiesen, Ellisiv B.
    Matijasevich, Alicia
    Matsha, Tandi E.
    Mbanya, Jean Claude N.
    Posso, Anselmo J. Mc Donald
    McFarlane, Shelly R.
    McGarvey, Stephen T.
    McLachlan, Stela
    McLean, Rachael M.
    McNulty, Breige A.
    Khir, Amir Sharifuddin Md
    Mediene-Benchekor, Sounnia
    Medzioniene, Jurate
    Meirhaeghe, Aline
    Meisinger, Christa
    Menezes, Ana Maria B.
    Menon, Geetha R.
    Meshram, Indrapal I.
    Metspalu, Andres
    Mi, Jie
    Mikkel, Kairit
    Miller, Jody C.
    Francisco Miquel, Juan
    Jaime Miranda, J.
    Misigoj-Durakovic, Marjeta
    Mohamed, Mostafa K.
    Mohammad, Kazem
    Mohammadifard, Noushin
    Mohan, Viswanathan
    Yusoff, Muhammad Fadhli Mohd
    Moller, Niels C.
    Molnar, Denes
    Momenan, Amirabbas
    Monyeki, Kotsedi Daniel K.
    Moreira, Leila B.
    Morejon, Alain
    Moreno, Luis A.
    Morgan, Karen
    Moschonis, George
    Mossakowska, Malgorzata
    Mostafa, Aya
    Mota, Jorge
    Motlagh, Mohammad Esmaeel
    Motta, Jorge
    Muiesan, Maria L.
    Mueller-Nurasyid, Martina
    Murphy, Neil
    Mursu, Jaakko
    Musil, Vera
    Nagel, Gabriele
    Naidu, Balkish M.
    Nakamura, Harunobu
    Namsna, Jana
    Nang, Ei Ei K.
    Nangia, Vinay B.
    Narake, Sameer
    Maria Navarrete-Munoz, Eva
    Ndiaye, Ndeye Coumba
    Neal, William A.
    Nenko, Ilona
    Nervi, Flavio
    Nguyen, Nguyen D.
    Nguyen, Quang Ngoc
    Nieto-Martinez, Ramfis E.
    Niiranen, Teemu J.
    Ning, Guang
    Ninomiya, Toshiharu
    Nishtar, Sania
    Noale, Marianna
    Noboa, Oscar A.
    Noorbala, Ahmad Ali
    Norat, Teresa
    Noto, Davide
    Al Nsour, Mohannad
    O'Reilly, Dermot
    Oh, Kyungwon
    Olinto, Maria Teresa A.
    Oliveira, Isabel O.
    Omar, Mohd Azahadi
    Onat, Altan
    Ordunez, Pedro
    Osmond, Clive
    Ostojic, Sergej M.
    Otero, Johanna A.
    Overvad, Kim
    Owusu-Dabo, Ellis
    Paccaud, Fred Michel
    Padez, Cristina
    Pahomova, Elena
    Pajak, Andrzej
    Palli, Domenico
    Palmieri, Luigi
    Panda-Jonas, Songhomitra
    Panza, Francesco
    Papandreou, Dimitrios
    Parnell, Winsome R.
    Parsaeian, Mahboubeh
    Pecin, Ivan
    Pednekar, Mangesh S.
    Peer, Nasheeta
    Peeters, Petra H.
    Peixoto, Sergio Viana
    Pelletier, Catherine
    Peltonen, Markku
    Pereira, Alexandre C.
    Marina Perez, Rosa
    Peters, Annette
    Petkeviciene, Janina
    Pham, Son Thai
    Pigeot, Iris
    Pikhart, Hynek
    Pilav, Aida
    Pilotto, Lorenza
    Pitakaka, Freda
    Plans-Rubio, Pedro
    Polakowska, Maria
    Polasek, Ozren
    Porta, Miquel
    Portegies, Marileen L. P.
    Pourshams, Akram
    Pradeepa, Rajendra
    Prashant, Mathur
    Price, Jacqueline F.
    Puiu, Maria
    Punab, Margus
    Qasrawi, Radwan F.
    Qorbani, Mostafa
    Radic, Ivana
    Radisauskas, Ricardas
    Rahman, Mahfuzar
    Raitakari, Olli
    Raj, Manu
    Rao, Sudha Ramachandra
    Ramos, Elisabete
    Rampal, Sanjay
    Rangel Reina, Daniel A.
    Rasmussen, Finn
    Redon, Josep
    Reganit, Paul Ferdinand M.
    Ribeiro, Robespierre
    Riboli, Elio
    Rigo, Fernando
    de Wit, Tobias F. Rinke
    Ritti-Dias, Raphael M.
    Robinson, Sian M.
    Robitaille, Cynthia
    Rodriguez-Artalejo, Fernando
    Rodriguez-Villamizar, Laura A.
    Rojas-Martinez, Rosalba
    Rosengren, Annika
    Rubinstein, Adolfo
    Rui, Ornelas
    Sandra Ruiz-Betancourt, Blanca
    Russo Horimoto, Andrea R. V.
    Rutkowski, Marcin
    Sabanayagam, Charumathi
    Sachdev, Harshpal S.
    Saidi, Olfa
    Sakarya, Sibel
    Salanave, Benoit
    Salazar Martinez, Eduardo
    Salmeron, Diego
    Salomaa, Veikko
    Salonen, Jukka T.
    Salvetti, Massimo
    Sanchez-Abanto, Jose
    Sans, Susana
    Santos, Diana
    Santos, Ina S.
    dos Santos, Renata Nunes
    Santos, Rute
    Saramies, Jouko L.
    Sardinha, Luis B.
    Margolis, Giselle Sarganas
    Sarrafzadegan, Nizal
    Saum, Kai-Uwe
    Savva, Savvas C.
    Scazufca, Marcia
    Schargrodsky, Herman
    Schneider, Ione J.
    Schultsz, Constance
    Schutte, Aletta E.
    Sen, Abhijit
    Senbanjo, Idowu O.
    Sepanlou, Sadaf G.
    Sharma, Sanjib K.
    Shaw, Jonathan E.
    Shibuya, Kenji
    Shin, Dong Wook
    Shin, Youchan
    Siantar, Rosalynn
    Sibai, Abla M.
    Santos Silva, Diego Augusto
    Simon, Mary
    Simons, Judith
    Simons, Leon A.
    Sjotrom, Michael
    Skovbjerg, Sine
    Slowikowska-Hilczer, Jolanta
    Slusarczyk, Przemyslaw
    Smith, Margaret C.
    Snijder, Marieke B.
    So, Hung-Kwan
    Sobngwi, Eugene
    Söderberg, Stefan
    Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Medicine.
    Solfrizzi, Vincenzo
    Sonestedt, Emily
    Song, Yi
    Sorensen, Thorkild I. A.
    Jerome, Charles Sossa
    Soumare, Aicha
    Staessen, Jan A.
    Starc, Gregor
    Stathopoulou, Maria G.
    Stavreski, Bill
    Steene-Johannessen, Jostein
    Stehle, Peter
    Stein, Aryeh D.
    Stergiou, George S.
    Stessman, Jochanan
    Stieber, Jutta
    Stoeckl, Doris
    Stocks, Tanja
    Stokwiszewski, Jakub
    Stronks, Karien
    Strufaldi, Maria Wany
    Sun, Chien-An
    Sung, Yn-Tz
    Suriyawongpaisal, Paibul
    Sy, Rody G.
    Tai, E. Shyong
    Tammesoo, Mari-Liis
    Tamosiunas, Abdonas
    Tang, Line
    Tang, Xun
    Tanser, Frank
    Tao, Yong
    Tarawneh, Mohammed Rasoul
    Tarqui-Mamani, Carolina B.
    Taylor, Anne
    Theobald, Holger
    Thijs, Lutgarde
    Thuesen, Betina H.
    Tjonneland, Anne
    Tolonen, Hanna K.
    Topbas, Murat
    Topor-Madry, Roman
    Jose Tormo, Maria
    Torrent, Maties
    Traissac, Pierre
    Trichopoulos, Dimitrios
    Trichopoulou, Antonia
    Trinh, Oanh T. H.
    Trivedi, Atul
    Tshepo, Lechaba
    Tulloch-Reid, Marshall K.
    Tuomainen, Tomi-Pekka
    Turley, Maria L.
    Tynelius, Per
    Tzourio, Christophe
    Ueda, Peter
    Ugel, Eunice
    Ulmer, Hanno
    Uusitalo, Hannu M. T.
    Valdivia, Gonzalo
    Valvi, Damaskini
    van der Schouw, Yvonne T.
    Van Herck, Koen
    van Rossem, Lenie
    van Valkengoed, Irene G. M.
    Vanderschueren, Dirk
    Vanuzzo, Diego
    Vatten, Lars
    Vega, Tomas
    Velasquez-Melendez, Gustavo
    Veronesi, Giovanni
    Verschuren, W. M. Monique
    Verstraeten, Roosmarijn
    Victora, Cesar G.
    Viet, Lucie
    Viikari-Juntura, Eira
    Vineis, Paolo
    Vioque, Jesus
    Virtanen, Jyrki K.
    Visvikis-Siest, Sophie
    Viswanathan, Bharathi
    Vollenweider, Peter
    Vrdoljak, Ana
    Vrijheid, Martine
    Wade, Alisha N.
    Wagner, Aline
    Walton, Janette
    Mohamud, Wan Nazaimoon Wan
    Wang, Ming-Dong
    Wang, Qian
    Wang, Ya Xing
    Wannamethee, S. Goya
    Wareham, Nicholas
    Wederkopp, Niels
    Weerasekera, Deepa
    Whincup, Peter H.
    Widhalm, Kurt
    Widyahening, Indah S.
    Wiecek, Andrzej
    Wijga, Alet H.
    Wilks, Rainford J.
    Willeit, Peter
    Williams, Emmanuel A.
    Wilsgaard, Tom
    Wojtyniak, Bogdan
    Wong, Tien Yin
    Wong-McClure, Roy A.
    Woo, Jean
    Wu, Aleksander Giwercman
    Wu, Frederick C.
    Wu, Shou Ling
    Xu, Haiquan
    Yan, Weili
    Yang, Xiaoguang
    Ye, Xingwang
    Yiallouros, Panayiotis K.
    Yoshihara, Akihiro
    Younger-Coleman, Novie O.
    Yusoff, Ahmad F.
    Zambon, Sabina
    Zdrojewski, Tomasz
    Zeng, Yi
    Zhao, Dong
    Zhao, Wenhua
    Zheng, Yingffeng
    Zhu, Dan
    Zimmermann, Esther
    Zuniga Cisneros, Julio
    Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19.1 million participants2017In: The Lancet, ISSN 0140-6736, E-ISSN 1474-547X, Vol. 389, no 10064, 37-55 p.Article in journal (Refereed)
    Abstract [en]

    Methods: For this analysis, we pooled national, subnational, or community population-based studies that had measured blood pressure in adults aged 18 years and older. We used a Bayesian hierarchical model to estimate trends from 1975 to 2015 in mean systolic and mean diastolic blood pressure, and the prevalence of raised blood pressure for 200 countries. We calculated the contributions of changes in prevalence versus population growth and ageing to the increase in the number of adults with raised blood pressure.

    Findings: We pooled 1479 studies that had measured the blood pressures of 19·1 million adults. Global age-standardised mean systolic blood pressure in 2015 was 127·0 mm Hg (95% credible interval 125·7–128·3) in men and 122·3 mm Hg (121·0–123·6) in women; age-standardised mean diastolic blood pressure was 78·7 mm Hg (77·9–79·5) for men and 76·7 mm Hg (75·9–77·6) for women. Global age-standardised prevalence of raised blood pressure was 24·1% (21·4–27·1) in men and 20·1% (17·8–22·5) in women in 2015. Mean systolic and mean diastolic blood pressure decreased substantially from 1975 to 2015 in high-income western and Asia Pacific countries, moving these countries from having some of the highest worldwide blood pressure in 1975 to the lowest in 2015. Mean blood pressure also decreased in women in central and eastern Europe, Latin America and the Caribbean, and, more recently, central Asia, Middle East, and north Africa, but the estimated trends in these super-regions had larger uncertainty than in high-income super-regions. By contrast, mean blood pressure might have increased in east and southeast Asia, south Asia, Oceania, and sub-Saharan Africa. In 2015, central and eastern Europe, sub-Saharan Africa, and south Asia had the highest blood pressure levels. Prevalence of raised blood pressure decreased in high-income and some middle-income countries; it remained unchanged elsewhere. The number of adults with raised blood pressure increased from 594 million in 1975 to 1·13 billion in 2015, with the increase largely in low-income and middle-income countries. The global increase in the number of adults with raised blood pressure is a net effect of increase due to population growth and ageing, and decrease due to declining age-specific prevalence.

    Interpretation: During the past four decades, the highest worldwide blood pressure levels have shifted from high-income countries to low-income countries in south Asia and sub-Saharan Africa due to opposite trends, while blood pressure has been persistently high in central and eastern Europe.

  • Mattsson, Karin
    et al.
    Ersta Sköndal Bräcke University College, Department of Health Care Sciences. Mälardalens högskola.
    Pietilä Rosendahl, Sirpa
    Mälardalens högskola.
    Teaching gerontology in globalized academics: a qualitative study of Thai nursing students' views on ageing when studying abroad.2017In: Contemporary Nurse: health care across the lifespan, ISSN 1037-6178, E-ISSN 1839-3535, Vol. 53, no 1, 36-47 p.Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: Negative views towards ageing and older adults may be a reason why nurses do not choose to work in gerontological nursing. Studying in another cultural context can challenge these views. The Objective was to explore nursing students' views on ageing and older adults before and after a gerontology course held abroad.

    DESIGN AND METHOD: A qualitative approach based on content analysis of responses to open-ended questions by 30 Thai nursing students studying a gerontology course in Sweden.

    RESULTS: Three main categories: positive imprints of ageing, ageing takes its toll, and knowledge leading to action, emerged through sub-categories carrying a view of older adults as not only in need of care, but also as resourceful and competent. Professional healthcare, besides family was seen as potential caregivers in old age.

    CONCLUSIONS: Studying gerontology abroad can widen views towards ageing and older adults, inspiring nurses to work in gerontological nursing.

  • Andersson, Gunnar
    Stockholms universitet.
    Trends in Childbearing and Nuptiality in Sweden2001In: Nordic Demography in History and Present-Day Society / [ed] Lars-Göran Tedebrand and Peter Sköld, Umeå: Umeå universitet , 2001, 67-100 p.Chapter in book (Other academic)
  • Public defence: 2017-04-21 10:15 MA121, MIT-Huset, Umeå
    Gonzalo P., Rodrigo
    Umeå University, Faculty of Science and Technology, Department of Computing Science.
    HPC scheduling in a brave new world2017Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    Many breakthroughs in scientific and industrial research are supported by simulations and calculations performed on high performance computing (HPC) systems. These systems typically consist of uniform, largely parallel compute resources and high bandwidth concurrent file systems interconnected by low latency synchronous networks. HPC systems are managed by batch schedulers that order the execution of application jobs to maximize utilization while steering turnaround time. In the past, demands for greater capacity were met by building more powerful systems with more compute nodes, greater transistor densities, and higher processor operating frequencies. Unfortunately, the scope for further increases in processor frequency is restricted by the limitations of semiconductor technology. Instead, parallelism within processors and in numbers of compute nodes is increasing, while the capacity of single processing units remains unchanged. In addition, HPC systems’ memory and I/O hierarchies are becoming deeper and more complex to keep up with the systems’ processing power. HPC applications are also changing: the need to analyze large data sets and simulation results is increasing the importance of data processing and data-intensive applications. Moreover, composition of applications through workflows within HPC centers is becoming increasingly important. This thesis addresses the HPC scheduling challenges created by such new systems and applications. It begins with a detailed analysis of the evolution of the workloads of three reference HPC systems at the National Energy Research Supercomputing Center (NERSC), with a focus on job heterogeneity and scheduler performance. This is followed by an analysis and improvement of a fairshare prioritization mechanism for HPC schedulers. The thesis then surveys the current state of the art and expected near-future developments in HPC hardware and applications, and identifies unaddressed scheduling challenges that they will introduce. These challenges include application diversity and issues with workflow scheduling or the scheduling of I/O resources to support applications. Next, a cloud-inspired HPC scheduling model is presented that can accommodate application diversity, takes advantage of malleable applications, and enables short wait times for applications. Finally, to support ongoing scheduling research, an open source scheduling simulation framework is proposed that allows new scheduling algorithms to be implemented and evaluated in a production scheduler using workloads modeled on those of a real system. The thesis concludes with the presentation of a workflow scheduling algorithm to minimize workflows’ turnaround time without over-allocating resources.

  • Chen, Chunli
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Biosciences.
    Ortega, Fatima
    Diseases of Developing World Medicines Development Campus, GlaxoSmithKline, Madrid, Spain.
    Rullas, Joaquin
    Diseases of Developing World Medicines Development Campus, GlaxoSmithKline, Madrid, Spain.
    Alameda, Laura
    Diseases of Developing World Medicines Development Campus, GlaxoSmithKline, Madrid, Spain.
    Angulo-Barturen, Iñigo
    Diseases of Developing World Medicines Development Campus, GlaxoSmithKline, Madrid, Spain.
    Ferrer, Santiago
    Diseases of Developing World Medicines Development Campus, GlaxoSmithKline, Madrid, Spain.
    Svensson, Ulrika S H
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Biosciences.
    The multistate tuberculosis pharmacometric model: a semi-mechanistic pharmacokinetic-pharmacodynamic model for studying drug effects in an acute tuberculosis mouse model2017In: Journal of Pharmacokinetics and Pharmacodynamics, ISSN 1567-567X, E-ISSN 1573-8744Article in journal (Refereed)
    Abstract [en]

    The Multistate Tuberculosis Pharmacometric (MTP) model, a pharmacokinetic-pharmacodynamic disease model, has been used to describe the effects of rifampicin on Mycobacterium tuberculosis (M. tuberculosis) in vitro. The aim of this work was to investigate if the MTP model could be used to describe the rifampicin treatment response in an acute tuberculosis mouse model. Sixty C57BL/6 mice were intratracheally infected with M. tuberculosis H37Rv strain on Day 0. Fifteen mice received no treatment and were sacrificed on Days 1, 9 and 18 (5 each day). Twenty-five mice received oral rifampicin (1, 3, 9, 26 or 98 mg·kg-1·day-1; Days 1–8; 5 each dose level) and were sacrificed on Day 9. Twenty mice received oral rifampicin (30 mg·kg-1·day-1; up to 8 days) and were sacrificed on Days 2, 3, 4 and 9 (5 each day). The MTP model was linked to a rifampicin population pharmacokinetic model to describe the change in colony forming units (CFU) in the lungs over time. The transfer rates between the different bacterial states were fixed to estimates from in vitro data. The MTP model described well the change in CFU over time after different exposure levels of rifampicin in an acute tuberculosis mouse model. Rifampicin significantly inhibited the growth of fast-multiplying bacteria and stimulated the death of fast- and slow-multiplying bacteria. The data did not support an effect of rifampicin on non-multiplying bacteria possibly due to the short duration of the study. The pharmacometric modelling framework using the MTP model can be used to perform investigations and predictions of the efficacy of anti-tubercular drugs against different bacterial states.

  • Fritsche, Carsten
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, Faculty of Science & Engineering.
    On parametric smoothing Cramér-Rao bounds2017Report (Other academic)
    Abstract [en]

    In this report, the parametric Cramér-Rao lower bound for the smoothing problem is derived.

  • Saiang, David
    et al.
    Luleå University of Technology, Department of Civil, Environmental and Natural Resources Engineering, Mining and Geotechnical Engineering.
    Nordlund, Erling
    Luleå University of Technology, Department of Civil, Environmental and Natural Resources Engineering, Mining and Geotechnical Engineering.
    Numerical Analyses of Field Monitoring in Stope J10-3 at Kristineberg Mine2017Report (Refereed)
  • Boström, Per Staffan
    Mälardalen University, School of Business, Society and Engineering, Industrial Economics and Organisation. Linköpings Universitet IEI.
    RESURSTILLVÄXT.: Målet för hållbar tillväxt.Manuscript (preprint) (Other (popular science, discussion, etc.))
    Abstract [sv]

    Bokprojektet ”HÅLLBAR TILLVÄXT – 2000-talets ledarutmaning” 

    Detta bokrojekt som nu föreligger i ett första manus är uppstarten på en logitudinell och företagsnära forksning om hållbart och resurseffektivt företagande. Projektet som påbörjades 2002  är framförallt engagerat i frågan hur begreppet ”Sustainable Growth”, hållbar tillväxt, ska bli lättare att kommunicera och förstå för att vara användbart i företagets affärsverksamhet. Projektet har genomförts i samarbetet med ett antal företag. Successivt har det också uppstått ett behov att finna ett tydligt mål, en enkel formel och en arbetsform för det långsiktiga beslut och styrning mot om ekonomiskt hållbar tillväxt av alla resurser (per definition) i en organisation. Projektet avhandlar därför betydelsen av begreppet RESURSTILLVÄXT.

  • Ahmadi, Fereshteh
    et al.
    University of Gävle, Faculty of Health and Occupational Studies, Department of Social Work and Psychology, Social work.
    Palm, Irving
    Sociologiska institutionen, Uppsala universitet, Uppsala.
    Ahmadi, Nader
    University of Gävle, Faculty of Health and Occupational Studies, Department of Social Work and Psychology, Social work.
    Mångfaldsbarometern 20162016Report (Other academic)
    Abstract [sv]
    1. Erfarenheterna från människor med utländsk bakgrund fortfarande goda Erfarenheterna från att ha kollegor med utländsk bakgrund i skolan eller på jobbet är goda hos 70 procent av befolkningen och stabila över tiden. En av tio har dåliga erfarenheter. Ju högre utbildning man har desto bättre erfarenheter. Respondenter med låg utbildning och pensionärer saknar relativt ofta helt erfarenhet från människor med utländsk bakgrund.
    2. Försämrade attityder till att ge utlandsfödda sociala och kulturella rättigheter En majoritet tycker att nyanlända skall ha samma sociala rättigheter som personer födda i Sverige – men de positiva attityderna har minskat från 77 procent år 2014 till 55 procent i årets mätning. Knappt hälften av respondenterna vill skapa förutsättningar för människor att bevara sina kulturella traditioner, och även här kan en tydlig minskning skönjas jämfört med 2014. Dessa försämrade attityder återfinns bland såväl kvinnor och män, som unga och gamla.
    3. Allmänt mångfaldsindex sjunker och tangerar lägsta nivå Fortfarande är 64 procent av befolkningen positiva till mångfald men andelen minskar med 10 procentenheter. Försämrade attityder till mångfald märks bland kvinnor och de i medelåldern.
    4. Positiva attityder till mångfald i ett arbetsperspektiv – men något försämrade Fortfarande är de positiva till mångfald en betydligt större grupp än de negativa i ett arbetsperspektiv. Men de negativa attityderna ökar något sedan 2014, bl.a. bland kvinnorna.
    5. Attityderna till mångfald i ett religionsperspektiv har försämrats Kvinnorna har i ett religionsperspektiv nästan blivit lika negativa som män. Försämrade attityder har också skett bland akademiker som annars är de mest positiva. Nästan hälften av de boende i Sverige hävdar att alla religioner inte har samma värderingar och särskiljer då framförallt Islam.
    6. Negativa attityder till människor från Afrika och Mellanöstern i ett boendeperspektiv Var tredje boende i Sverige föredrar personer födda i Sverige som grannar. Men det beror mycket på varifrån grannen kommer. Attityderna är betydligt sämre mot eventuella grannar från Afrika eller Mellanöstern då dessa grupper enligt många är förenat med problem.
    7. Majoritet för att etnisk mångfald utvecklar den svenska kulturen – men attityderna försämras Hälften av de tillfrågade uppfattar stora olikheter mellan den inhemska kulturen och kulturer från Afrika och Mellanöstern. Människor från dessa länder anses vara svårintegrerade i samhället.

     

  • Public defence: 2017-04-20 14:00 E51, Stockholm
    Niazi Ardekani, Mehdi
    KTH, School of Engineering Sciences (SCI), Mechanics.
    Numerical study of non-spherical/spherical particles in laminar and turbulent flows2017Licentiate thesis, comprehensive summary (Other academic)
    Abstract [en]

    The presence of solid rigid particles alters the global transport and rheological properties of the mixture in complex (and often unpredictable) ways. In recent years a few studies have been devoted to investigating the behavior of dense suspensions in the turbulent/inertial regime with the majority of theses analyses limited to mono-disperse rigid neutrally-buoyant spheres. However, one interesting parameter that is rarely studied for particles with high inertia is the particle shape. Spheroidal particles introduce an anisotropy, e.g. a tendency to orient in a certain direction, which can affect the bulk behavior of a suspension in an unexpected ways. The main focus of this study is therefore to investigate the behavior of spheroidal particles and their effect on turbulent/inertial flows.

    We perform fully resolved simulations of particulate flows with spherical/spheroidal particles, using an efficient/accurate numerical approach that enables us to simulate thousands of particles with high resolutions in order to capture all the fluid-solid interactions.

    Several conclusions are drawn from this study that reveal the importance of particle's shape effect on the behaviour of a suspension e.g. spheroidal particles tend to cluster while sedimenting. This phenomenon is observed in this work for both particles with high inertia, sedimenting in a quiescent fluid and inertialess particles (point-like tracer prolates) settling in homogenous isotropic turbulence. The mechanisms for clustering is indeed different between these two situations, however, it is the shape of particles that governs these mechanisms, as clustering is not observed for spherical particles. Another striking finding of this work is drag reduction in particulate turbulent channel flow with rigid oblate particles. Again this drag reduction is absent for spherical particles, which instead increase the drag with respect to single-phase turbulence. 

  • Bergström, Jonas
    et al.
    SCB.
    Eklund, Veronica
    SCB.
    Gerner, Annika
    SCB.
    Szudy, Mikael
    SCB.
    Danielsson, Helena
    Executive, Forskningsinstitut, IVL Swedish Environmental Research Institute.
    Preliminär skattning av utsläpp av växthusgaser 20122013Report (Other academic)
    Abstract [sv]

    Sammanfattning

    Naturvårdsverket har fått ett informellt uppdrag från regeringskansliet att rapportera grovt uppskattade utsläpp av växthusgaser för år 2012 den 15 april 2013.

    Med tanke på den tidigarelagda publiceringen av preliminära utsläppsskattningar 2012 levereras skattningarna med en något annan sektorsindelning än till ordinarie rapportering. Utsläppen redovisas i Gg CO2-ekvivalenter totalt samt per sektor enligt den modifierade sektorsindelningen. Metodiken baseras i huvudsak på SMED 20121. Förutsättningarna och metodvalet skiljer sig åt mellan olika sektorer. För utsläpp från energiproduktion och transporter samt i viss mån industriprocesser och avfallsförbränning har data avseende 2012 funnits tillgängliga och utnyttjats. Utsläpp från jordbruk och avfallshantering exklusive förbränning har skattats genom framskrivning av tidigare års utsläpp med linjär regression.

    Resultatet av beräkningarna blev att Sveriges totala utsläpp av växthusgaser 2012 uppgick till 58 260 Gg CO2-ekvivalenter exklusive utrikes transporter. Det innebär en minskning med 5 procent jämfört med 2011 års utsläpp enligt submission 2013. Totalt 76 procent av utsläppen har beräknats baserat på uppdaterade data avseende 2012. Resultatet är preliminärt och 2012 års utsläpp kommer i viss mån att revideras till ordinarie submission 2014

  • Redaktionens tack: Granskare 2013–20162017In: Sociologisk forskning, ISSN 0038-0342, Vol. 54, no 1, 157-158 p.Article in journal (Other academic)
  • Recensioner2017In: Sociologisk forskning, ISSN 0038-0342, Vol. 54, no 1, 135-155 p.Article, book review (Other academic)
  • Holmberg, Tora
    et al.
    Sjöstrand, Glenn
    Sociologförbundet har ordet: Sociologförbundets arbete med ämnes-/gymnasielärarutbildningen2017In: Sociologisk forskning, ISSN 0038-0342, Vol. 54, no 1, 133-134 p.Article in journal (Other academic)
  • Muftee, Mehek
    Jönköpings universitet.
    Vidarebosättning, Sverigeprogram och föreställningen om den ”passiva flyktingen”2017In: Sociologisk forskning, ISSN 0038-0342, Vol. 54, no 1, 111-132 p.Article in journal (Refereed)
    Abstract [en]

    Resettlement, Swedenprogram, and the notion of the "passive refugee"

    This study analyzes discourses of refugees as manifested in a part of the Swedish resettlement work called the Swedenprogram. The aim of the programs is to, through dialogue; actively involve refugees in their resettlement. The program can be situated within an overall increased emphasis on activating refugees and asylum seekers in order for them to take responsibility for their integration. Video observations were carried out of nine Swedenprograms that were held in Kenya and Sudan. The information provided by the delegations is based on the notion of ideal citizen as active, responsible, and engaged in self-fulfillment. However, the study also shows that the information given to the youth positions them as potentially lacking these traits. The idea of the passive refugee permeates the information in different ways and includes a gender aspect. The study also shows how the youths navigate and sometimes resist the stereotype positioning of themselves.

  • Behtoui, Alireza
    Södertörns högskola; Stockholms universitet.
    "Främlingen" bland svensk "Homo Academicus"2017In: Sociologisk forskning, ISSN 0038-0342, Vol. 54, no 1, 91-110 p.Article in journal (Refereed)
    Abstract [en]

    The ”stranger” among Swedish ”Homo Academicvs”

    This paper is about individuals with immigrant background among the Swedish academic elite, i.e. those who have a PhD and work at Swedish universities. The aim of the study is to understand how factors other than academic qualifications, such as gender and a migrant background, may impact on the individual’s ability to get a job and pursue a successful career in Swedish higher education. The data used for this study is obtained from the Longitudinal Database of Education, Income and Occupation (LISA) administered by Statistics Sweden.When compared to the reference group (individuals born in Sweden with at least one Swedish-born parent), the results show that given the same work experience individuals born in Eastern Europe, Asia, Africa and South America are more likely to be unemployed. Among those who have a job, those

  • Wimark, Thomas
    et al.
    Stockholms universitet.
    Hedlund, Daniel
    Stockholms universitet.
    Samlevnad som ideologi i migrationslagstiftningen2017In: Sociologisk forskning, ISSN 0038-0342, Vol. 54, no 1, 69-90 p.Article in journal (Refereed)
    Abstract [en]

    Cohabitation as ideology in migration law

    In this study we study how homosexuality has legally gone from exclusion to inclusion in migration law and what ideological understandings that underpin this inclusion. The data corpus of the study consisted of the preparatory work concerning same-sex sexuality, cohabitation and migration. Data was coded for patterns concerning the public administrative understandings of same-sex sexuality as described in the preparatory works. The coding was theoretically driven by critical and Marxist approaches to ideology. Conducting a thematic analysis, four themes were identified in the data. The overall finding is that the preparatory works give precedence to sexuality in terms of disposition (läggning) when it is linked to identity and intensions to engage in a long-term relationship. This means that alternative sexual identities and practices not compatible with the ”heterosexual matrix” have been excluded from the ideological lens. The ideological focus in the preparatory works could be seen as a reflection of the capitalist system, where some social categories are viewed as desirable to include in a capitalist society.

  • Public defence: 2017-04-21 10:00 Skoog-salen, Uppsala
    Jonsson, Eva Lindell
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Otolaryngology and Head and Neck Surgery.
    Biomolecular markers in head and neck cancer2017Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    Head and neck cancer is a heterogeneous group of tumours, of which certain subgroups such as cancer of the mobile tongue frequently are associated with a relatively poor prognosis due to the high risk of regional failure and mortality rates that haven’t improved in a significant way over the last 3 decades, despite advancements in both diagnostics and treatment.

    Today we lack means to assess the biological aggressiveness of each individual tumour, which varies largely. Treatment comprises of surgery with additional radiotherapy and medical therapies in more advanced tumours.

    The focus in this thesis is on molecular biomarker expression in head and neck cancer and especially in association with radiotherapy. Increased knowledge paves the way to a more individualized cancer treatment aiming for better outcome and less overtreatment and sequelae.

    The aims of this thesis was:

    • To map the effects of radiotherapy in both tumour and adjacent tissue for the possible markers hyaluronan, EGFR and mast cells.
    • To investigate whether the expression of hyaluronan in the epithelium and connective tissue stroma and EGFR in the tumour correlates with the risk for developing cervical metastasis in N0 patients, and to find out whether the 3-year tumour-specific survival rates correlates with the expression of HA in the epithelium and EGFR in the tumour.
    • To establish an animal model for radiation-induced mucositis and to use that model to examine the pattern of invading inflammatory cells.
    • To investigate whether the expression of podoplanin in tongue cancer correlates with the risk for cervical metastasis and to determine whether the total amount of lymph vessels in the diagnostic biopsy has any impact on the clinical outcome.
    • To investigate the differences in the metabolome of tongue cancer cell lines with different radiosensitivity.

    The most important findings of this thesis were:

    • The expression of EGFR and hyaluronan hade the same pattern of expression in both tumour and adjacent tissues before radiotherapy. The expression of EGFR was increased in the epithelium of the adjacent tissue close to the tumour after radiotherapy.
    • The intensity of the staining of hyaluronan was correlated to the 3-year survival rates in patients with tongue cancer.
    • An experimental model for radiation-induced oral mucositis in rat was established and in this model a temporal pattern of macrophage invasion with two different subtypes of macrophages was found.
    • There were no correlation between the expression of podoplanin in the tumour tissue and the cervical metastasis rate in patients with tongue cancer, but the younger patients were more likely to have a higher expression of podoplanin in their tumour than elder patients.
    • Tongue cancer cell lines with different radiosensitivity respond to irradiation with different patterns of metabolic expressions. 
  • Bergnehr, Disa
    Jönköpings universitet.
    Omsorg för dagen och fostran för en framtid: Irakiska mödrars strategier för att skapa tillhörighet i Sverige2017In: Sociologisk forskning, ISSN 0038-0342, Vol. 54, no 1, 51-68 p.Article in journal (Refereed)
    Abstract [en]

    Caring in the present and fostering for the future: Iraqi mothers’ reconstruction of belonging during resettlement in Sweden

    The present study explores Iraqi women’s mothering strategies for protecting, nurturing, and training their child, as well as how they use different approaches to (re)construct feelings of belonging during the process of resettlement. It is qualitative in design and based on individual interviews as well as focus groups discussions with a total of 27 women. Narrative method has inspired the analysis. The results show a child-centred motherhood with everyday practices aimed at creating a sense of safety and belonging for the child. Belonging to the family is central. The child’s societal and future belonging is connected to educational achievement, with prospects of employment and upward mobility. Accordingly, the mothers apply strategies aimed at promoting such a life trajectory. However, aspirations for belonging in the future can sometimes conflict with belonging at the present. In addition, striving to create belonging for the child can be in conflict with the parents’ sense of belonging.

  • Bengtson, Stefan
    et al.
    Swedish Museum of Natural History, Department of Paleobiology.
    Sallstedt, Therese
    Swedish Museum of Natural History, Department of Paleobiology.
    Belivanova, Veneta
    Swedish Museum of Natural History, Department of Paleobiology.
    Whitehouse, Martin
    Swedish Museum of Natural History, Department of Geology.
    Three-dimensional preservation of cellular and subcellular structures suggests 1.6 billion-year-old crown-group red algae2017In: PLoS biology, ISSN 1544-9173, E-ISSN 1545-7885, Vol. 15, no 3, 1-38 p., e2000735Article in journal (Refereed)
    Abstract [en]

    The ~1.6 Ga Tirohan Dolomite of the Lower Vindhyan in central India contains phosphatized stromatolitic microbialites. We report from there uniquely well-preserved fossils interpreted as probable crown-group rhodophytes (red algae). The filamentous form Rafatazmia chitrakootensis n. gen, n. sp. has uniserial rows of large cells and grows through diffusely distributed septation. Each cell has a centrally suspended, conspicuous rhomboidal disk interpreted as a pyrenoid. The septa between the cells have central structures that may represent pit connections and pit plugs. Another filamentous form, Denaricion mendax n. gen., n. sp., has coin-like cells reminiscent of those in large sulfur-oxidizing bacteria but much more recalcitrant than the liquid-vacuole-filled cells of the latter. There are also resemblances with oscillatoriacean cyanobacteria, although cell volumes in the latter are much smaller. The wider affinities of Denaricion are uncertain. Ramathallus lobatus n. gen., n. sp. is a lobate sessile alga with pseudoparenchymatous thallus, “cell fountains,” and apical growth, suggesting florideophycean affinity. If these inferences are correct, Rafatazmia and Ramathallus represent crown-group multicellular rhodophytes, antedating the oldest previously accepted red alga in the fossil record by about 400 million years.

  • Arheimer, Berit
    et al.
    Executive, Myndigheter, Sveriges meteorologiska och hydrologiska institut, SMHI.
    Pers, Charlotta
    Executive, Myndigheter, Sveriges meteorologiska och hydrologiska institut, SMHI.
    Kväveretention i svenska sjöar och vattendrag – betydelse för utsläpp från reningsverk2007Report (Other academic)
    Abstract [en]

    This report has been compiled on request of the Swedish Environmental Protection

    Agency to facilitate the discussion with the EU Commission. The EU Commission has

    announced that it will take Sweden to the European Court of Justice for failing to ensure

    proper treatment of urban waste water according to the Urban Waste Water Treatment

    Directive (Directive 91/271/EEC). In Sweden natural nitrogen removal (retention) in

    waterbodies is considered as part of the treatment of emissions, when transported to the

    sea.

    Nitrogen retention is a well-known phenomenon that includes several natural

    biogeochemical processes, which permanently remove nitrogen from the water. The

    effect may be considerable in areas with many lakes. Sweden has 92 000 lakes larger than

    1 hectare. It is rather normal with 30-70% nitrogen retention in Swedish lakes and rivers.

    The main process for natural nitrogen retention is denitrification, which is the same

    process that is applied for biological treatment in waste water plants.

    Natural retention is hard to measure, however, and has to be estimated based on several

    assumptions like so many other fluxes in nature. In Sweden a model system has been

    developed for large-scale calculation of nutrient transport, including retention, from land

    to the sea, with relatively high geographic resolution. The system couples field-scale

    models with catchment models and is scientifically documented and reviewed. It has been

    applied since 1997 for international reporting to HELCOM. The catchment model (HBVNP)

    is tuned and evaluated against monitored time-series of measurements where such

    are available. The nitrogen retention that is calculated with HBV-NP is composed of

    nitrogen that is permanently transferred to the atmosphere and sediment, and which

    therefore will not further contribute to the eutrophication of water systems.

    3

    Both calculations and measurements show that the retention is largest in the summer,

    especially in areas with many lakes and high loads. The retention capacity of lakes differs

    geographically; in the northern part of the country it is low, while the lakes in the

    southern part of the country are more effective as nitrogen sinks. In Southern Sweden the

    mean retention is 30-40 kg ha-1 lake yr-1. In total about 30 000 tonnes nitrogen is reduced

    annually in lakes and rivers, and 70% of this is reduced in southern Sweden. For

    emissions in the interior of the country, the load is reduced considerably during the

    transport through rivers and lakes, especially for south-central Sweden where the

    retention in the lakes is high. The accumulated retention can be over 80% in certain areas.

    It is difficult to evaluate the model results, since nitrogen retention cannot be measured

    directly and is integrated for large areas and waterbodies. It is common to use other

    variables to judge the credibility of the retention calculations. The result of the HBV-NP

    model is continuously evaluated against time series of observations in watercourses, both

    discharge and nutrient concentration, when it is used operationally. The model is

    evaluated both visually and statistically. The agreement for discharge and water balance is

    normally good, while the nutrient concentration can deviate more from observations.

    Sensitivity studies show that the model is relatively robust. When the model is compared

    to other models or budget calculations, the deviations can normally be explained by

    different assumptions or input data. The HBV-NP model has about the same precision as

    other similar models, nevertheless, the water discharge normally shows better accuracy.

    For source apportionment calculations, the retention in the flow paths of the landscape is

    accumulated for the emissions from specific urban waste water treatment plants

    (UWWTP). The emissions that pass through many lakes have only small impact on the

    sea. Natural nitrogen retention in rivers and lakes reduces the Swedish UWWTP:s

    contribution to the coast with 3200 tonnes per year, which corresponds to 18% of their

    total emissions. However, the retention varies substantially between different parts of the

    country. Most of the UWWTP with large emissions are located along the coast and in

    southern Sweden, where 90% of the natural retention occurs. In the interior of northern

    Sweden there are few UWWTP and the retention capacity is low, and thus, the amount of

    reduced nitrogen is also low.

    Everything indicates that the calculated nitrogen retention for Sweden is of the right

    magnitude and that the large-scale pattern for Sweden is correct, even if deviation can

    occur for small specific areas and for different time-periods

  • Dahlstedt, Magnus
    et al.
    Linköpings universitet.
    Fejes, Andreas
    Linköpings universitet.
    Olson, Maria
    Dalarna University, School of Education, Health and Social Studies, Educational Work.
    Rahm, Lina
    Linköpings universitet.
    Sandberg, Fredrik
    Lunds universitet; Linköpings universitet.
    Medborgarskapandets paradoxer: Medborgarskapspositioneringar i berättelser om tillhörigheti migrationens tid2017In: Sociologisk forskning, ISSN 0038-0342, Vol. 54, no 1, 31-50 p.Article in journal (Refereed)
    Abstract [en]

    Paradoxes of citizen formation: Citizenship positioning in stories about belonging in an era of migration

    This article analyzes the formation of citizenship in today’s multi-ethnic Sweden with a particular focus on how migration renders visible existing citizenship ideals, defined in terms of similarity and difference on the basis of ethno-cultural background. Analysing three individual stories of women who have migrated to Sweden, with different biographies and stories of how they ended up in Sweden, the article focuses on negotiations of the boundaries and contents of citizenship in multi-ethnic Sweden. The point of departure for the analysis is a post-structuralist and discursive approach. In all, the stories address the crucial question of who should be included into the social community and on what conditions – and who should be left out? This particular question is also at the very centre of the political debate in today’s Europe. On the one hand, there are strong arguments about the ’death of multiculturalism’ and demands for new forms of ethno-culturally graduated citizenship – also in Sweden. On the other hand, in Sweden as well as in other European countries, claims for the development of a new and more inclusive societal community have been raised, expanding the rights of citizens to accommodating also those who have been excluded from them.

  • Hochwallner, Martin
    et al.
    Linköping University, Department of Management and Engineering, Fluid and Mechatronic Systems. Linköping University, Faculty of Science & Engineering.
    Landberg, Magnus
    Linköping University, Department of Management and Engineering, Fluid and Mechatronic Systems. Linköping University, Faculty of Science & Engineering.
    Krus, Petter
    Linköping University, Department of Management and Engineering, Fluid and Mechatronic Systems. Linköping University, Faculty of Science & Engineering.
    The Hydraulic Infinite Linear Actuator: properties relevant for control2016In: 10th International Fluid Power Conference (10. IFK), 2016, Vol. 3, 411-424 p.Conference paper (Refereed)
    Abstract [en]

    Rotational hydraulic actuators, e.g. motors, provide infinite stroke as there is no conceptual limit to how far they can turn. By contrast linear hydraulic actuators like cylinders provide only limited stroke by concept. In the world of electrical drives, linear motors provide infinite stroke also for linear motion. In hydraulics, the presented Hydraulic Infinite Linear Actuator is a novelty. This paper presents the novel Hydraulic Infinite Linear Actuator (HILA). The contribution is an assessment of properties relevant for control like high hydraulic stiffness and is based on analysis, simulation and measurements. The Hydraulic Infinite Linear Actuator -- properties relevant for control. Available from: https://www.researchgate.net/publication/298164471_The_Hydraulic_Infinite_Linear_Actuator_--_properties_relevant_for_control [accessed Mar 28, 2017].

  • Kele, Malin
    et al.
    Karolinska Inst, Dept Neurosci, Retziusvag 8, S-17177 Stockholm, Sweden..
    Day, Kelly
    Karolinska Inst, Dept Neurosci, Retziusvag 8, S-17177 Stockholm, Sweden..
    Ronnholm, Harriet
    Karolinska Inst, Dept Neurosci, Retziusvag 8, S-17177 Stockholm, Sweden..
    Schuster, Jens
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Immunology, Genetics and Pathology, Medicinsk genetik och genomik. Uppsala University, Science for Life Laboratory, SciLifeLab.
    Dahl, Niklas
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Immunology, Genetics and Pathology, Medicinsk genetik och genomik. Uppsala University, Science for Life Laboratory, SciLifeLab.
    Falk, Anna
    Karolinska Inst, Dept Neurosci, Retziusvag 8, S-17177 Stockholm, Sweden..
    Generation of human iPS cell line CTL07-II from human fibroblasts, under defined and xeno-free conditions2016In: Stem Cell Research, ISSN 1873-5061, E-ISSN 1876-7753, Vol. 17, no 3, 474-478 p.Article in journal (Refereed)
    Abstract [en]

    CTL07-II is a healthy feeder-free and characterized human induced pluripotent stem (iPS) cell line. Cultured under xeno-free and defined conditions. The line is generated from healthy human fibroblasts with non-integrating Sendai virus vectors encoding the four Yamanaka factors, OCT4, SOX2, KLF4 and cMYC. The generated iPS cells are free from reprogramming vectors and their purity, karyotypic stability and pluripotent capacity is confirmed.

  • Khayati, Khalid
    Linköpings universitet.
    Stigmatisering och rasism i det svenska migrationssamtalet och det diasporiska motståndet2017In: Sociologisk forskning, ISSN 0038-0342, Vol. 54, no 1, 11-30 p.Article in journal (Refereed)
    Abstract [en]

    Stigmatization and racism in the Swedish migration talk and the diasporic resistance

    This article argues that the objectifying and stigmatizing characteristics ascribed to the refugee and immigrant populations in the current Swedish refugee debate and the existing discriminatory and racializing practices in Sweden should be analyzed far beyond the recent refugee problematic and the global terrorism related to the political Islam. This study upholds in that way that the practices of objectification, stigmatization, racialization and exclusion get strength from a broader and deeper political context. In this context, the existence of a race biological institute, the project of the Swedish folkhem and its cultural boundaries, the emergence of a systematic discrimination against refugees and immigrants since the mid-1980s and related acts of violence depict the outlines of a white and (mono)cultural Swedish ”imagined community” which disregards the power, dynamism and subjectivity of immigrant and refugee groups. In this respect, the notion of diaspora, which will be illustrated by the Kurdish diaspora in Sweden, constitutes an important platform of resistance as it claims the political recognition for other ethnicities than the native Swede.

  • Dahlstedt, Magnus
    et al.
    Eliassi, Barzoo
    Salmonsson, Lisa
    Medborgarskap och tillhörighet i migrationens tid – inledande reflektioner2017In: Sociologisk forskning, ISSN 0038-0342, Vol. 54, no 1, 5-10 p.Article in journal (Refereed)
  • Edling, Christofer
    et al.
    Lunds universitet.
    Eldén, Sara
    Lunds universitet.
    Redaktörerna har ordet2017In: Sociologisk forskning, ISSN 0038-0342, Vol. 54, no 1, 3- p.Article in journal (Other academic)
  • Edling, Christofer
    et al.
    Lunds universitet.
    Eldén, SaraLunds universitet.
    Sociologisk Forskning 2017:12017Collection (editor) (Refereed)
  • Public defence: 2017-04-19 09:00 Fire, Solna
    Krishnan, Kalaiselvan
    KTH, School of Engineering Sciences (SCI), Applied Physics.
    Studies on molecular mechanisms in calcium signaling and cellular energy consumption2017Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    Ion signaling plays fundamental role in cell survival. Na+ and Ca2+ are critical players in ion signaling. Cells spend the major amount of energy to maintain and regulate Na+ and Ca2+ gradients across the cell membrane. Any disruption in cellular energy consumption by plasma membrane ATPases affects ion signaling and vice versa. This thesis is a combination of four separate research studies. In the first study, We measured ATP consumption dynamics of Na+/K+-ATPase using a genetically encoded fluorescent indicator called Perceval HR. we demonstrate that PercevalHR is an excellent tool to visualize ATP:ADP in mammalian cells.

    In the second study, We studied the role of calcium signaling and TRP channels in angiotensin II type 1 receptor  signaling cascade. We prove that low inhibition of CaV1.2 with physiological and therapeutically relevant concentration of Angiotensin II up regulate AT1R signaling.

    In the third study, We studied the role of the TRPM5 channel in regulating insulin secretion, and cytoplasmic free calcium concentration in the rat β-cells by usingtriphenyl phosphine oxide, a selective inhibitor of the channel.

    In the fourth study, We tested whether, the genetically engineered human β-cell line (EndoC-BH1) could be used as models for studying Ca2+signaling in the context of Type II Diabetes. We found that the EndoC-BH1 cells could be a relevant model to study stimulus-secretion coupling and Ca2+ signaling in the human β-cells.

  • Krishnan, Kalaiselvan
    et al.
    KTH, School of Engineering Sciences (SCI), Applied Physics.
    Ma, Zuheng
    Karolinska Institutet.
    Björklund, Anneli
    Karolinska institutet.
    Islam, Md.Shahidul
    Karolinska institutet.
    Calcium signaling in a genetically engineered human pancreatic β-cell line2015In: Pancreas, ISSN 0885-3177, E-ISSN 1536-4828, Vol. 44, no 5, 773-777 p.Article in journal (Refereed)
    Abstract [en]

    Objectives: The use of primary human β-cells for studying Ca2+ signalingis limited by the scarcity of human pancreatic islets. Rodent insulinomacell lines are widely used, but it is difficult to extrapolate results obtainedfrom rodent cells to human. Recently, a genetically engineered humanβ-cell line EndoC-BH1 has been developed. We have examined whetherthe EndoC-BH1 cells could be used as a model for studying Ca2+ signalingin the β-cells.Methods: We used microscope-based fluorometry to measure cytoplasmicfreeCa2+ concentration from fura-2–loaded single EndoC-BH1 cellscultured on glass cover slips. Ca2+ responses to different agonists of insulinsecretion were studied. Insulin secretion was measured by radioimmunoassay.Results: EndoC-BH1 cells secreted insulin in response to glucose ina dose-dependent manner, and the secretion was enhanced by GLP-1(glucagon-like peptide 1). Glucose, potassium chloride, carbachol, L-arginine,and tolbutamide increased cytoplasmic-free Ca2+ concentration in theEndoC-BH1 cells. We found that GLP-1 was essential for Ca2+ responseto glucose and tolbutamide.Conclusions: We concluded that the EndoC-BH1 cells can be used asmodel cells to study Ca2+ signaling and stimulus-secretion coupling inthe human β-cells.

  • Krishnan, Kalaiselvan
    et al.
    KTH, School of Engineering Sciences (SCI), Applied Physics.
    Ma, Zuheng
    Karolinska Institutet.
    Björklund, Anneli
    Karolinska Insititutet.
    Islam, Md.Shahidul
    Karolinska Institutet.
    Role of TRPM5 channel in insulin secretion from rat β-cells.: TRPM5 and insulin secretion2014In: Pancreas, ISSN 0885-3177, E-ISSN 1536-4828, Vol. 43, no 4, 597-604 p.Article in journal (Refereed)
    Abstract [en]

    OBJECTIVE:

    Several studies have reported that the transient receptor potential melastatin-like subtype 5 (TRPM5) channel, a Ca(2+)-activated monovalent cation channel, is involved in the stimulus-secretion coupling in the mouse pancreatic β-cells. We have studied the role of the TRPM5 channel in regulating insulin secretion and cytoplasmic free Ca(2+) concentration ([Ca(2+)](i)) in the rat β-cells by using triphenylphosphine oxide, a selective inhibitor of the channel.

    METHODS:

    Insulin secretion from islets from Sprague-Dawley rats was measured in batch incubations. Cytoplasmic free Ca(2+) concentration was measured from single β-cells by fura-2-based microfluorometry.

    RESULTS:

    Triphenylphosphine oxide did not alter insulin secretion and [Ca(2+)](i) response triggered by KCl or fructose. It inhibited insulin secretion in response to glucose, L-arginine, and glucagon-like peptide 1. It also inhibited glucose-induced insulin secretion by mechanisms that are independent of the adenosine triphosphate-sensitive potassium channels and [Ca(2+)](i) increase.

    CONCLUSIONS:

    Our results suggest that in the rat islets, TRPM5 is involved in mediating insulin secretion by glucose and l-arginine and in potentiating the glucose-induced insulin secretion by glucagon-like peptide 1.

  • Arvidsson, Håkan
    Swedish National Road and Transport Research Institute, Infrastructure, Pavement Technology.
    Jämförande provning – Ballast 2015: flisighetsindex, korndensitet och kulkvarn2017Report (Other academic)
    Abstract [en]

    This report shows results, some statistical analysis and precision data for profiency testing (round-robin) performed on three materials of aggregate during 2015. The properties that was determined was Flakiness Index (EN 933-3), particle density (EN 1097-6) and Nordic ball mill (EN 1097-9). The number of participating laboratories were for Flakiness index 58 pcs., for particle density 60 pcs. and for Nordic ball mill 52 pcs.

    There are some scatter of the results which is not surprising. A few of the laboratories show clearly high or low results (for all three materials) for one of the analysis. Generally is the scatter in results varying. E.g. some of the laboratories have a clearly high result for one of the materials, a slightly low result for the second material and are quite close to the average for the third material.

    The standard deviations increase with increase in level of results (average), but not as much. The ratio of standard deviation and average decrease with increase of level.

    The precision data from this round-robin over all matches the levels from the test standards. The tests from this report has often a wider range of results. There is a correlation between reproducibility and level of average. The repeatability has not been calculated because tests actually have been performed as single tests.

    Analysis of background data, like handling, dimensions and type of model, shows that they have none or very little significance.

  • Zhu, Lin
    KTH, School of Technology and Health (STH), Basic Science and Biomedicine, Structural Biotechnology.
    Structural Studies of High Density Lipoprotein by Electron Microscopy and Flexible FittingManuscript (preprint) (Other academic)
  • Schäfer, Dorothea
    et al.
    Jönköping University, Jönköping International Business School, JIBS, Economics. German Institute for Economic Research DIW Berlin, Germany.
    Stephan, Andreas
    Jönköping University, Jönköping International Business School, JIBS, Economics. Jönköping University, Jönköping International Business School, JIBS, Center for Family Enterprise and Ownership (CeFEO). Linnæus University.
    Khanh, Trung Hoang
    DIW Berlin, Germany.
    The cost channel effect of monetary transmission: How effective is the ECB's low interest rate policy for increasing inflation?2017Report (Other academic)
    Abstract [en]

    We examine whether monetary transmission during the financial and sovereign debt crisis was dominated by the cost channel or by the demand-side channel effect. We use two approaches to track down the potential pass-through of changes in the monetary policy rate to those in consumer prices. First, we utilize panel data from the German manufacturing industry. Second, we conduct time series analyses for Germany, Italy, and Spain. We find that when manufacturing firms’ interest costs drop, the changes in their respective industry’s price index are smaller one year later. This finding is consistent with the cost channel theory. Taken together, the results of both panel data and time series analyses imply that the ECB’s low interest rate policy has worked better for boosting inflation in Italy and Spain than in Germany.

  • Cardemil, Carina
    et al.
    Department of Biomaterials, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, Department of Oral and Maxillofacial Surgery, Örebro University Hospital, Örebro, Sweden, BIOMATCELL VINN Excellence Center of Biomaterials and Cell Therapy, Gothenburg, Sweden .
    Elgali, Ibrahim
    Department of Biomaterials, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, BIOMATCELL VINN Excellence Center of Biomaterials and Cell Therapy, Gothenburg, Sweden.
    Xia, Wei
    Applied Materials Science, Department of Engineering Sciences, Uppsala University, Uppsala, Sweden, BIOMATCELL VINN Excellence Center of Biomaterials and Cell Therapy, Gothenburg, Sweden.
    Emanuelsson, Lena
    Department of Biomaterials, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, BIOMATCELL VINN Excellence Center of Biomaterials and Cell Therapy, Gothenburg, Sweden.
    Norlindh, Birgitta
    Department of Biomaterials, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, BIOMATCELL VINN Excellence Center of Biomaterials and Cell Therapy, Gothenburg, Sweden.
    Omar, Omar
    Department of Biomaterials, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, BIOMATCELL VINN Excellence Center of Biomaterials and Cell Therapy, Gothenburg, Sweden.
    Thomsen, Peter
    Department of Biomaterials, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, BIOMATCELL VINN Excellence Center of Biomaterials and Cell Therapy, Gothenburg, Sweden .
    Strontium-doped calcium phosphate and hydroxyapatite granules promote different inflammatory and bone remodelling responses in normal and ovariectomised rats2013In: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 8, no 12, e84932Article in journal (Refereed)
    Abstract [en]

    The healing of bone defects may be hindered by systemic conditions such as osteoporosis. Calcium phosphates, with or without ion substitutions, may provide advantages for bone augmentation. However, the mechanism of bone formation with these materials is unclear. The aim of this study was to evaluate the healing process in bone defects implanted with hydroxyapatite (HA) or strontium-doped calcium phosphate (SCP) granules, in non-ovariectomised (non-OVX) and ovariectomised (OVX) rats. After 0 (baseline), six and 28d, bone samples were harvested for gene expression analysis, histology and histomorphometry. Tumour necrosis factor-α (TNF-α), at six days, was higher in the HA, in non-OVX and OVX, whereas interleukin-6 (IL-6), at six and 28d, was higher in SCP, but only in non-OVX. Both materials produced a similar expression of the receptor activator of nuclear factor kappa-B ligand (RANKL). Higher expression of osteoclastic markers, calcitonin receptor (CR) and cathepsin K (CatK), were detected in the HA group, irrespective of non-OVX or OVX. The overall bone formation was comparable between HA and SCP, but with topological differences. The bone area was higher in the defect centre of the HA group, mainly in the OVX, and in the defect periphery of the SCP group, in both non-OVX and OVX. It is concluded that HA and SCP granules result in comparable bone formation in trabecular bone defects. As judged by gene expression and histological analyses, the two materials induced different inflammatory and bone remodelling responses. The modulatory effects are associated with differences in the spatial distribution of the newly formed bone.