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  • Teets, Jessica
    et al.
    Middlebury Coll, Dept Polit Sci, Middlebury, VT 05753 USA.
    Almén, Oscar
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Social Sciences, Department of Government.
    Advocacy under Xi: NPO Strategies to Influence Policy Change2018In: Nonprofit Policy Forum, ISSN 1799-3954, E-ISSN 1892-2686, Vol. 9, no 1, article id 20170028Article in journal (Refereed)
    Abstract [en]

    Under the Hu-Wen administration, scholars analyzed how political opportunity structures (POS) affect the policy influence of NPOs in China, and found that the opportunity structure was relatively more open, especially for NPOs using personal connections. In this article, we focus on changes in the opportunity structure since Xi Jinping came to power after 2012, and find that the more closed political climate has had important consequences for NPO policy advocacy. We identify three strategies that NPOs have used to advocate, such as using the law, media framing, and establishing expert status. While these strategies are not novel, we argue that the weighting has shifted in terms of what leads to success.

  • Mokdad, Ali H.
    et al.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Moradi-Lakeh, Maziar
    Iran Univ Med Sci, Dept Community Med, Gastrointestinal & Liver Dis Res Ctr GILDRC, Preventat Med & Publ Hlth Res Ctr, Tehran, Iran.
    El Bcheraoui, Charbel
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Khalil, Ibrahim
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Charara, Raghid
    Amer Univ Beirut, Beirut, Lebanon.
    Afshin, Ashkan
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Wang, Haidong
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Collison, Michael
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Krohn, Kristopher J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Chew, Adrienne
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Daoud, Farah
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Blosser, Christopher D.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Cornaby, Leslie
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Foreman, Kyle J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Kassebaum, Nicholas J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA;Seattle Childrens Hosp, Dept Anesthesiol & Pain Med, Seattle, WA USA.
    Kemmer, Laura
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Kutz, Michael
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Liu, Patrick
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Zipkin, Ben
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Arnlov, Johan
    Karolinska Inst, Div Family Med & Primary Care, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden;Dalarna Univ, Sch Hlth & Social Studies, Falun, Sweden.
    Abate, Kalkidan Hassen
    Jimma Univ, Jimma, Oromia, Ethiopia.
    Ahmadi, Alireza
    Kermanshah Univ Med Sci, Kermanshah, Iran.
    Ahmadieh, Hamid
    Shahid Beheshti Univ Med Sci, Ophthalm Res Ctr, Tehran, Iran;Labbafinejad Med Ctr, Dept Ophthalmol, Tehran, Iran.
    Ahmed, Muktar Beshir
    Jimma Univ, Coll Hlth Sci, Dept Epidemiol, Oromiya, Ethiopia.
    Al-Aly, Ziyad
    Washington Univ, St Louis, MO USA.
    Alam, Khurshid
    Univ Melbourne, Murdoch Childrens Res Inst, Parkville, Vic, Australia;Univ Melbourne, Melbourne, Vic, Australia;Univ Sydney, Sydney, NSW, Australia.
    Alasfoor, Deena
    Minist Hlth, Muscat, Oman.
    Ali, Raghib
    Univ Oxford, Oxford, England.
    Alizadeh-Navaei, Reza
    Mazandaran Univ Med Sci ences, Gastrointestinal Canc Res Ctr, Sari, Mazandaran, Iran.
    Alkaabi, Juma M.
    Coll Med & Hlth Sci UAEU, ALAIN UAE, Abu Zaby, U Arab Emirates.
    Alkerwi, Ala'a
    LIH, Luxembourg, Luxembourg.
    Al-Raddadi, Rajaa
    Joint Program Family & Community Med, Jeddah, Saudi Arabia.
    Altirkawi, Khalid A.
    King Saud Univ, Riyadh, Saudi Arabia.
    Alvis-Guzman, Nelson
    Univ Cartagena, Cartagena De Indias, Colombia.
    Amini, Erfan
    Univ Tehran Med Sci, Urooncol Res Ctr, Tehran, Iran;Univ Tehran Med Sci, Endocrinol & Metab Res Inst, Noncommunicable Dis Res Ctr, Tehran, Iran.
    Anber, Nahla
    Mansoura Univ, Mansoura, Egypt.
    Anwari, Palwasha
    Asgedom, Solomon Weldegebreal
    Mekelle Univ, Mekelle, Tigray, Ethiopia.
    Atey, Tesfay Mehari
    Mekelle Univ, Mekelle, Tigray, Ethiopia.
    Avila-Burgos, Leticia
    Natl Inst Publ Hlth, Cuernavaca, Morelos, Mexico.
    Awasthi, Ashish
    Sanjay Gandhi Postgrad Inst Med Sci, Lucknow, Uttar Pradesh, India.
    Azzopardi, Peter
    Univ Melbourne, Dept Paediat, Melbourne, Vic, Australia;Murdoch Childrens Res Inst, Melbourne, Vic, Australia;South Australian Hlth & Med Res Inst, Wardliparingga Aboriginal Res Unit, Adelaide, SA, Australia;Burnet Inst, Ctr Int Hlth, Melbourne, Vic, Australia.
    Baernighausen, Till
    Harvard Univ, Harvard TH Chan Sch Publ Hlth, Dept Global Hlth & Populat, Boston, MA 02115 USA;Africa Hlth Res Inst, Mtubatuba, Kwazulu Natal, South Africa;Heidelberg Univ, Inst Publ Hlth, Heidelberg, Germany.
    Bacha, Umar
    Univ Management & Technol, Sch Hlth Sci, Lahore, Punjab, Pakistan.
    Barac, Aleksandra
    Univ Belgrade, Fac Med, Belgrade, Serbia.
    Bazargan-Hejazi, Shahrzad
    Charles R Drew Univ Med & Sci, Coll Med, 1621 E 120th St, Los Angeles, CA 90059 USA;Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90095 USA.
    Drew, Charles R.
    Geffen, David
    Bedi, Neeraj
    Coll Publ Hlth & Trop Med, Jazan, Saudi Arabia.
    Berhe, Derbew Fikadu
    Mekelle Univ, Sch Pharm, Mekelle, Tigray, Ethiopia.
    Beyene, Addisu Shunu
    Haramaya Univ, Coll Hlth & Med Sci, Harar, Oromia, Ethiopia.
    Bhutta, Zulfiqar A.
    Aga Khan Univ, Ctr Excellence Women & Child Hlth, Karachi, Pakistan;Hosp Sick Children, Ctr Global Child Hlth, Toronto, ON, Canada.
    Bikbov, Boris
    Haramaya Univ, Ctr Excellence Women & Child Hlth, Harar, Oromia, Ethiopia.
    Birhanu, Mulugeta M.
    Univ Groningen, UMCG, Groningen, Netherlands;Mekelle Univ, Mekelle 03, Ayder, Ethiopia.
    Butt, Zahid A.
    Al Shifa Trust Eye Hosp, Rawalpindi, Punjab, Pakistan.
    Cahuana-Hurtado, Lucero
    Natl Inst Publ Hlth, Cuernavaca, Morelos, Mexico.
    Carpenter, David O.
    SUNY Albany, Albany, NY USA.
    Carrero, Juan Jesus
    Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden.
    Choi, Jee-Young Jasmine J.
    Seoul Natl Univ Hosp, Seoul, South Korea;Seoul Natl Univ, Med Lib, Seoul, South Korea.
    Danawi, Hadi
    Walden Univ, Minneapolis, MN USA.
    Dharmaratne, Samath D.
    Univ Peradeniya, Dept Community Med, Fac Med, Peradeniya, Sri Lanka.
    Ding, Eric L.
    Harvard Univ, Harvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA.
    Djalalinia, Shirin
    Minist Hlth & Med Educ Tehran, Undersecretary Res & Technol, Tehran, Iran.
    Doyle, Kerrie E.
    RMIT Univ, Bundoora, Vic, Australia;Australian Natl Univ, Canberra, ACT, Australia.
    Ebrahimi, Hedyeh
    Univ Tehran Med Sci, Noncommunicable Dis Res Ctr, Tehran, Iran;Univ Tehran Med Sci, Digest Dis Res Inst, Shariati Hosp, Liver & Pancreaticobiliary Dis Res Ctr, Tehran, Iran.
    Endries, Aman Yesuf
    Arba Minch Univ, Arba Minch, Arba Minch, Snnpr, Ethiopia.
    Esteghamati, Alireza
    Univ Tehran Med Sci, Endocrinol & Metab Res Ctr, Tehran, Iran.
    Farvid, Maryam S.
    Harvard Univ, Dept Nutr, Harvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA;Massachusetts Gen Hosp, Mongan Inst Hlth Policy, Harvard MGH Ctr Genom Vulnerable Populat & Hlth D, Boston, MA 02114 USA.
    Fereshtehnejad, Seyed-Mohammad
    Karolinska Inst, Dept Neurobiol Care Sci & Soc NVS, Stockholm, Sweden.
    Feyissa, Tesfaye Regassa
    Wollega Univ, Nekemte, Oromia, Ethiopia.
    Fischer, Florian
    Univ Bielefeld, Bielefeld, North Rhine Wes, Germany.
    Gebrehiwot, Tsegaye Tewelde
    Jimma Univ, Jimma, Oromia, Ethiopia.
    Gona, Philimon N.
    Univ Massachusetts, Boston, MA 02125 USA.
    Gopalani, Sameer Vali
    Govern Federated States Micronesia, Dept Hlth & Social Affairs, Palikir, Pohnpei, Micronesia.
    Gyawali, Bishal
    Aarhus Univ, Aarhus, Denmark.
    Hafezi-Nejad, Nima
    Univ Tehran Med Sci, Endocrinol & Metab Res Ctr, Tehran, Iran.
    Hamadeh, Randah Ribhi
    Arabian Gulf Univ, Manama, Bahrain.
    Hamidi, Samer
    Hamdan Bin Mohammed Smart Univ, Dubai, U Arab Emirates.
    Horino, Masako
    Bur Child Family Community Wellness, Nevada Div Publ & Behav Hlth, Carson City, NV USA.
    Hsairi, Mohamed
    Salah Azaiz Inst, Dept Epidemiol, Tunis, Tunisia.
    Jakovljevic, Mihajlo B.
    Univ Kragujevac Kragujevac, Cent Serbia Sumadija, Fac Med Sci, Kragujevac, Serbia;Univ Washington, IHME, Ctr Hlth Trends & Forecasts, Seattle, WA 98195 USA.
    Jimenez-Corona, Aida
    Inst Ophthalmol Condede Valencia, Dept Ocular Epidemiol & Visual Hlth, Mexico City, DF, Mexico;Minist Hlth, Gen Directorate Epidemiol, Mexico City, DF, Mexico.
    John, Denny
    Int Ctr Res Women, Delhi, India.
    Jonas, Jost B.
    Heidelberg Univ, Med Fac Mannheim, Dept Ophthalmol, Mannheim, Germany.
    Kasaeian, Amir
    Univ Tehran Med Sci, Hematol Oncol & Stem Cell Transplantat Res Ctr, Tehran, Iran;Univ Tehran Med Sci, Endocrinol & Metab Populat Sci Inst, Tehran, Iran.
    Kengne, Andre Pascal
    South African Med Res Council, Cape Town, Western Cape, South Africa;Univ Cape Town, Cape Town, Western Cape, South Africa.
    Ketema, Ezra Belay
    Mekelle Univ, Mekelle, Tigray, Ethiopia.
    Khader, Yousef Saleh
    Jordan Univ Sci & Technol, Dept Community Med Publ Hlth & Family Med, Irbid, Jordan.
    Khan, Ejaz Ahmad
    Hlth Serv Acad, Islamabad, Punjab, Pakistan.
    Kim, Daniel
    Northeastern Univ, Dept Hlth Sci, Boston, MA 02115 USA.
    Kim, Yun Jin
    Southern Univ Coll, Fac Chinese Med, Skudai, Malaysia.
    Kinfu, Yohannes
    Univ Canberra, Ctr Res & Action Publ Hlth, Canberra, ACT, Australia.
    Kissimova-Skarbek, Katarzyna A.
    Jagiellonian Univ Med Coll, Krakow, Poland.
    Koyanagi, Ai
    Parc Sanitari St Joan de Deu CIBERSAM, Res & Dev Unit, Barcelona, Spain.
    Larson, Heidi J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA;London Sch Hyg & Trop Med, Dept Infect Dis Epidemiol, London, England.
    Larsson, Anders
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Chemistry.
    Li, Yongmei
    San Francisco VA Med Ctr, San Francisco, CA USA.
    Lotufo, Paulo A.
    Univ Sao Paulo, Sao Paulo, Brazil.
    Lunevicius, Raimundas
    Aintree Univ Hosp Natl Hlth Serv Fdn Trust, Liverpool, Merseyside, England;Univ Liverpool, Sch Med, Liverpool, Merseyside, England.
    Majeed, Azeem
    Imperial Coll London, Dept Primary Care & Publ Hlth, London, England.
    Malekzadeh, Reza
    Univ Tehran Med Sci, Digest Dis Res Inst, Tehran, Iran.
    Malta, Deborah Carvalho
    Univ Fed Minas Gerais, Belo Horizonte, MG, Brazil.
    Mazidi, Mohsen
    Chinese Acad Sci, Inst Genet & Dev Biol, Key State Lab Mol Dev Biol, Beijing, Peoples R China.
    Memish, Ziad A.
    Saudi Minist Hlth, Riyadh, Saudi Arabia;Alfaisal Univ, Coll Med, Riyadh, Saudi Arabia.
    Mendoza, Walter
    United Nations Populat Fund, Lima, Peru.
    Mengistie, Mubarek Abera
    Jimma Univ, Jimma, Oromia, Ethiopia.
    Mensah, George A.
    NHLBI, Ctr Translat Res & Implementat Sci, NIH, Bethesda, MD USA.
    Mezgebe, Haftay Berhane
    Mekelle Univ, Mekelle, Tigray, Ethiopia.
    Miller, Ted R.
    Pacific Inst Res & Evaluat, Calverton, MD USA;Curtin Univ, Ctr Populat Hlth, Perth, WA, Australia.
    Mohammed, Muktar Sano Kedir
    Mizan Tepi Univ, Mizan Teferi, Ethiopia.
    Mohammed, Shafiu
    Heidelberg Univ, Inst Publ Hlth, Heidelberg, Germany;Ahmadu Bello Univ, Hlth Syst & Policy Res Unit, Zaria, Kaduna, Nigeria.
    Mueller, Ulrich O.
    Fed Inst Populat Res, Wiesbaden, Germany.
    Nagel, Gabriele
    Ulm Univ, Ulm, Germany.
    Nguyen, Cuong Tat
    Nguyen, Quyen Le
    Nong, Vuong Minh
    Noubiap, Jean Jacques N.
    Univ Cape Town, Cape Town, South Africa;Med Diagnost Ctr, Yaounde, Cameroon.
    Ogbo, Felix Akpojene
    Western Sydney Univ, Ctr Hlth Res, Sydney, NSW, Australia.
    Ortiz, Alberto
    IIS Fdn Jimenez Diaz UAM, Madrid, Spain.
    Ota, Erika
    St Lukes Int Univ, Tokyo, Tokyo, Japan.
    Patel, Tejas
    Mt Sinai Hlth Syst, New York, NY USA.
    Pearson-Stuttard, Jonathan
    Imperial Coll London, London, England.
    Perico, Norberto
    IRCCS Ist Ric Farmacol Mario Negri, Bergamo, Italy.
    Petzold, Max
    Univ Gothenburg, Hlth Metr Unit, Gothenburg, Sweden;Univ Witwatersrand, Johannesburg, South Africa.
    Pishgar, Farhad
    Univ Tehran Med Sci, Urooncol Res Ctr, Tehran, Iran;Univ Tehran Med Sci, Noncommunicable Dis Res Ctr, Tehran, Iran.
    Pourmalek, Farshad
    Univ British Columbia, Vancouver, BC, Canada.
    Qorbani, Mostafa
    Alborz Univ Med Sci, Noncommunicable Dis Res Ctr, Karaj, Iran.
    Rahimi-Movaghar, Vafa
    Univ Tehran Med Sci, Sina Trauma & Surg Res Ctr, Tehran, Iran.
    Rai, Rajesh Kumar
    Soc Hlth & Demog Surveillance, Suri, W Bengal, India.
    Rana, Saleem M.
    Contech Sch Publ Hlth, Lahore, Punjab, Pakistan;Contech Int Hlth Consultants, Lahore, Punjab, Pakistan.
    Rawaf, David Laith
    Imperial Coll London, WHO Collaborating Ctr, London, England;North Hampshire Hosp, Basingstroke, England;Univ Coll London Hosp, London, England.
    Rawaf, Salman
    Imperial Coll London, London, England.
    Remuzzi, Giuseppe
    IRCCS Ist Ric Farmacol Mario Negri, Bergamo, Italy;Azienda Socio Sanitaria Territoriale, Papa Giovanni23, Bergamo, Italy;Univ Milan, Dept Biomed & Clin Sci L Sacco, Milan, Italy.
    Renzaho, Andre M. N. N.
    Univ Western Sydney, Locked Bag 1797, Penrith, NSW 2751, Australia.
    Rezaei, Satar
    Kermanshah Univ Med Sci, Sch Publ Hlth, Kermanshah, Iran.
    Roshandel, Gholamreza
    Univ Tehran Med Sci, Digest Dis Res Inst, Tehran, Iran;Golestan Univ Med Sci, Golestan Res Ctr Gastroenterol & Hepatol, Gorgan, Iran.
    Bacher, Dietrich Rothen
    Ulm Univ, Inst Epidemiol & Med Biometry, Ulm, Germany.
    Safdarian, Mahdi
    Univ Tehran Med Sci, Sina Trauma & Surg Res Ctr, Tehran, Iran;Shahid Beheshti Univ Med Sci, Ophthalm Epidemiol Res Ctr, Tehran, Iran.
    Safi, Sare
    Safiri, Saeid
    Maragheh Univ Med Sci, Sch Nursing & Midwifery, Dept Publ Hlth, Managerial Epidemiol Res Ctr, Maragheh, Iran.
    Sahraian, Mohammad Ali
    Univ Tehran Med Sci, Res Ctr, Inst Neurosci, Tehran, Iran.
    Salamati, Payman
    Univ Tehran Med Sci, Sina Trauma & Surg Res Ctr, Tehran, Iran.
    Samy, Abdallah M.
    Ain Shams Univ, Cairo, Egypt.
    Sanabria, Juan Ramon
    Marshall Univ, J Edwards Sch Med, Huntington, WV USA;Case Western Reserve Univ, Cleveland, OH 44106 USA.
    Dolores Sanchez-Nino, Maria
    IIS Fdn Jimenez Diaz, Madrid, Spain.
    Milicevic, Milena M. Santric
    Univ Belgrade, Inst Social Med, Fac Med, Belgrade, Serbia;Univ Belgrade, Ctr Sch Publ Hlth & Hlth Management, Fac Med, Belgrade, Serbia.
    Sartorius, Benn
    Univ KwaZulu Natal, Sch Nursing & Publ Hlth, Publ Hlth Med, Durban, South Africa;SAMRC, UKZN Gastrointestinal Canc Res Ctr, Durban, South Africa.
    Sepanlou, Sadaf G.
    Univ Tehran Med Sci, Digest Dis Res Inst, Tehran, Iran.
    Shaikh, Masood Ali
    Santos Silva, Diego Augusto
    Univ Fed Santa Catarina, Florianopolis, SC, Brazil.
    Alves Silveira, Dayane Gabriele
    Brasilia Univ, Brasilia, DF, Brazil.
    Sobaih, Badr H. A.
    King Saud Univ, Riyadh, Saudi Arabia.
    Abdulkader, Rizwan Suliankatchi
    Minist Hlth, Riyadh, Saudi Arabia.
    Tabares-Seisdedos, Rafael
    Univ Valencia, Incliva Hlth Res Inst, Dept Med, Valencia, Spain;CIBERSAM, Valencia, Spain.
    Tehrani-Banihashemi, Arash
    Iran Univ Med Sci, Prevent Med & Publ Hlth Res Ctr, Tehran, Iran.
    Temsah, Mohamad-Hani
    King Saud Univ, Riyadh, Saudi Arabia;King Faisal Specialist Hosp & Res Ctr, Riyadh, Saudi Arabia.
    Topor-Madry, Roman
    Jagiellonian Univ Med Coll, Inst Publ Hlth, Fac Hlth Sci, Krakow, Poland;Wroclaw Med Univ, Fac Hlth Sci, Wroclaw, Poland.
    Tran, Bach Xuan
    Johns Hopkins Univ, Baltimore, MD USA;Hanoi Med Univ, Hanoi, Vietnam.
    Ukwaja, Kingsley Nnanna
    Fed Teaching Hosp, Dept Internal Med, Abakaliki, Ebonyi State, Nigeria.
    Uthman, Olalekan A.
    Univ Warwick, Warwick Med Sch, Coventry, W Midlands, England.
    van Boven, Job F. M.
    Univ Groningen, Groningen, Netherlands.
    Wakayo, Tolassa
    Jimma Univ, Jimma, Oromia, Ethiopia.
    Werdecker, Andrea
    German Natl Cohort, Fed Inst Populat Res, Competence Ctr Mortal Follow Up, Wiesbaden, Germany.
    Workicho, Abdulhalik
    Jimma Univ, Jimma, Oromia, Ethiopia;Univ Ghent, Ghent, Belgium.
    Yaghoubi, Mohsen
    Univ Saskatchewan, Saskatoon, SK, Canada.
    Yano, Yuichiro
    Northwestern Univ, Dept Prevent Med, Chicago, IL 60611 USA.
    Yaseri, Mehdi
    Shahid Beheshti Univ Med Sci, Ophthalm Epidemiol Res Ctr, Tehran, Iran;Univ Tehran Med Sci, Tehran, Iran.
    Yonemoto, Naohiro
    Kyoto Univ, Sch Publ Hlth, Dept Biostat, Kyoto, Japan.
    Younis, Mustafa Z.
    Jackson State Univ, Jackson, MS USA.
    Zhang, Anthony Lin
    RMIT Univ, Sch Hlth & Biomed Sci, Bundoora, Vic, Australia.
    Jumaan, Aisha O.
    Vos, Theo
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Naghavi, Mohsen
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Hay, Simon I.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA;Univ Oxford, Oxford Big Data Inst, LiKa Shing Ctr Hlth Informat & Discovery, Oxford, England.
    Murray, Christopher J. L.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Diabetes mellitus and chronic kidney disease in the Eastern Mediterranean Region: findings from the Global Burden of Disease 2015 study2018In: International Journal of Public Health, ISSN 1661-8556, E-ISSN 1661-8564, Vol. 63, p. 177-186Article in journal (Refereed)
    Abstract [en]

    We used findings from the Global Burden of Disease 2015 study to update our previous publication on the burden of diabetes and chronic kidney disease due to diabetes (CKD-DM) during 1990-2015. We extracted GBD 2015 estimates for prevalence, mortality, and disability-adjusted life years (DALYs) of diabetes (including burden of low vision due to diabetes, neuropathy, and amputations and CKD-DM for 22 countries of the EMR from the GBD visualization tools. In 2015, 135,230 (95% UI 123,034-148,184) individuals died from diabetes and 16,470 (95% UI 13,977-18,961) from CKD-DM, 216 and 179% increases, respectively, compared to 1990. The total number of people with diabetes was 42.3 million (95% UI 38.6-46.4 million) in 2015. DALY rates of diabetes in 2015 were significantly higher than the expected rates based on Socio-demographic Index (SDI). Our study showed a large and increasing burden of diabetes in the region. There is an urgency in dealing with diabetes and its consequences, and these efforts should be at the forefront of health prevention and promotion.

  • Muelhopt, Sonja
    et al.
    Karlsruhe Inst Technol, Inst Tech Chem, D-76131 Karlsruhe, Germany.
    Diabate, Silvia
    Karlsruhe Inst Technol, Inst Toxicol & Genet, D-76131 Karlsruhe, Germany.
    Dilger, Marco
    Karlsruhe Inst Technol, Inst Toxicol & Genet, D-76131 Karlsruhe, Germany.
    Adelhelm, Christel
    Karlsruhe Inst Technol, Inst Appl Mat, D-76131 Karlsruhe, Germany.
    Anderlohr, Christopher
    Karlsruhe Inst Technol, Inst Tech Thermodynam & Refrigerat ITTK, D-76131 Karlsruhe, Germany.
    Bergfeldt, Thomas
    Karlsruhe Inst Technol, Inst Appl Mat, D-76131 Karlsruhe, Germany.
    Gómez de la Torre, Johan
    Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Nanotechnology and Functional Materials.
    Jiang, Yunhong
    Univ Bath, Dept Architecture & Civil Engn, Claverton Down, Bath BA2 7AY, Avon, England.
    Valsami-Jones, Eugenia
    Univ Birmingham, Sch Geog Earth & Environm Sci, Birmingham B15 2TT, W Midlands, England.
    Langevin, Dominique
    Univ Paris Saclay, Univ Paris Sud 11, CNRS UMR 8502, Lab Phys Solides, F-91190 St Aubin, France.
    Lynch, Iseult
    Univ Birmingham, Sch Geog Earth & Environm Sci, Birmingham B15 2TT, W Midlands, England.
    Mahon, Eugene
    Univ Coll Dublin, Sch Chem & Chem Biol, Ctr BioNano Interact, Dublin 4, Ireland.
    Nelissen, Inge
    Flemish Inst Technol Res VITO, Dept Hlth, B-2400 Mol, Belgium.
    Piella, Jordi
    CSIC, Catalan Inst Nanosci & Nanotechnol ICN2, Barcelona 08036, Spain;Barcelona Inst Sci & Technol, Barcelona 08036, Spain.
    Puntes, Victor
    CSIC, Catalan Inst Nanosci & Nanotechnol ICN2, Barcelona 08036, Spain;Barcelona Inst Sci & Technol, Barcelona 08036, Spain.
    Ray, Sikha
    Karlsruhe Inst Technol, STN, D-76131 Karlsruhe, Germany.
    Schneider, Reinhard
    Karlsruhe Inst Technol, LEM, D-76131 Karlsruhe, Germany.
    Wilkins, Terry
    Univ Leeds, Sch Chem & Proc Engn, Fac Engn, Leeds LS2 9JT, W Yorkshire, England.
    Weiss, Carsten
    Karlsruhe Inst Technol, Inst Toxicol & Genet, D-76131 Karlsruhe, Germany.
    Paur, Hanns-Rudolf
    Karlsruhe Inst Technol, Inst Tech Chem, D-76131 Karlsruhe, Germany.
    Characterization of Nanoparticle Batch-To-Batch Variability2018In: NANOMATERIALS, ISSN 2079-4991, Vol. 8, no 5, article id 311Article in journal (Refereed)
    Abstract [en]

    A central challenge for the safe design of nanomaterials (NMs) is the inherent variability of NM properties, both as produced and as they interact with and evolve in, their surroundings. This has led to uncertainty in the literature regarding whether the biological and toxicological effects reported for NMs are related to specific NM properties themselves, or rather to the presence of impurities or physical effects such as agglomeration of particles. Thus, there is a strong need for systematic evaluation of the synthesis and processing parameters that lead to potential variability of different NM batches and the reproducible production of commonly utilized NMs. The work described here represents over three years of effort across 14 European laboratories to assess the reproducibility of nanoparticle properties produced by the same and modified synthesis routes for four of the OECD priority NMs (silica dioxide, zinc oxide, cerium dioxide and titanium dioxide) as well as amine-modified polystyrene NMs, which are frequently employed as positive controls for nanotoxicity studies. For 46 different batches of the selected NMs, all physicochemical descriptors as prioritized by the OECD have been fully characterized. The study represents the most complete assessment of NMs batch-to-batch variability performed to date and provides numerous important insights into the potential sources of variability of NMs and how these might be reduced.

  • Mokdad, Ali H.
    et al.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Azzopardi, Peter
    SAHMRI, Wardliparingga Aboriginal Res Unit, Adelaide, SA, Australia.
    Cini, Karly
    Ctr Adolescent Hlth, Murdoch Childrens Res Inst, Melbourne, Vic, Australia.
    Kennedy, Elissa
    Burnet Inst, Melbourne, Vic, Australia. Murdoch Childrens Res Inst, Melbourne, Vic, Australia.
    Sawyer, Susan
    Univ Melbourne, Murdoch Childrens Res Inst, Parkville, Vic, Australia.
    El Bcheraoui, Charbel
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Charara, Raghid
    Amer Univ Beirut, Beirut, Lebanon.
    Khalil, Ibrahim
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Moradi-Lakeh, Maziar
    Iran Univ Med Sci, Dept Community Med, Prevent Med & Publ Hlth Res Ctr, Gastrointestinal & Liver Dis Res Ctr GILDRC, Tehran, Iran.
    Collison, Michael
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Afifi, Rima A.
    Amer Univ Beirut, Beirut, Lebanon.
    Al-Raiby, Jamela
    WHO, Cairo, Egypt.
    Krohn, Kristopher J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Daoud, Farah
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Chew, Adrienne
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Afshin, Ashkan
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Foreman, Kyle J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA;Imperial Coll London, London, England.
    Kassebaum, Nicholas J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA;Seattle Childrens Hosp, Dept Anesthesiol & Pain Med, Seattle, WA USA.
    Kutz, Michael
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Kyu, Hmwe H.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Liu, Patrick
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Olsen, Helen E.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Smith, Alison
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Stanaway, Jeffrey D.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Wang, Haidong
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Arnlov, Johan
    Karolinska Inst, Div Family Med & Primary Care, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden;Dalarna Univ, Sch Hlth & Social Studies, Falun, Sweden.
    Kiadaliri, Aliasghar Ahmad
    Lund Univ, Dept Clin Sci Lund, Clin Epidemiol Unit, Orthoped, Lund, Sweden.
    Alam, Khurshid
    Univ Melbourne, Murdoch Childrens Res Inst, Parkville, Vic, Australia;Univ Melbourne, Melbourne, Vic, Australia;Univ Sydney, Sydney, NSW, Australia.
    Alasfoor, Deena
    Minist Hlth, Muscat, Oman.
    Ali, Raghib
    Univ Oxford, Oxford, England.
    Alizadeh-Navaei, Reza
    Mazandaran Univ Med Sci, Gastrointestinal Canc Res Ctr, Sari, Mazandaran, Iran.
    Al-Raddadi, Rajaa
    Joint Program Family & Community Med, Jeddah, Makkah, Saudi Arabia.
    Altirkawi, Khalid A.
    King Saud Univ, Riyadh, Saudi Arabia.
    Alvis-Guzman, Nelson
    Univ Cartagena, Cartagena De Indias, Colombia.
    Anber, Nahla
    Mansoura Univ, Mansoura, Egypt.
    Antonio, Carl Abelardo T.
    Univ Philippines Manila, Dept Hlth Policy & Adm, Coll Publ Hlth, Manila, Philippines.
    Anwari, Palwasha
    Artaman, Al
    Univ Manitoba, Winnipeg, MB, Canada.
    Asayesh, Hamid
    Qom Univ Med Sci, Sch Paramed, Dept Med Emergency, Qom, Iran.
    Barker-Collo, Suzanne L.
    Univ Auckland, Sch Psychol, Auckland, New Zealand.
    Bedi, Neeraj
    Coll Publ Hlth & Trop Med, Jazan, Saudi Arabia.
    Beghi, Ettore
    IRCCS, Ist Ric Farmacol Mario Negri, Milan, Italy.
    Bennett, Derrick A.
    Univ Oxford, Nuffield Dept Populat Hlth, Oxford, England.
    Bensenor, Isabela M.
    Univ Sao Paulo, Sao Paulo, Brazil.
    Bhutta, Zulfiqar A.
    Aga Khan Univ, Ctr Excellence Women & Child Hlth, Karachi, Pakistan;Hosp Sick Children, Ctr Global Child Hlth, Toronto, ON, Canada.
    Butt, Zahid A.
    Al Shifa Trust Eye Hosp, Rawalpindi, Pakistan.
    Castaneda-Orjuela, Carlos A.
    Colombian Natl Hlth Observ, Inst Nacl Salud, Bogota, DC, Colombia;Univ Nacl Colombia, Publ Hlth Dept, Epidemiol & Publ Hlth Evaluat Grp, Bogota, Colombia.
    Catala-Lopez, Ferran
    Univ Valencia, Dept Med, INCLIVA Hlth Res Inst, Valencia, Spain;CIBERSAM, Valencia, Spain;Ottawa Hosp Res Inst, Clin Epidemiol Program, Ottawa, ON, Canada.
    Charlson, Fiona J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA;Queensland Ctr Mental Hlth Res, Brisbane, Qld, Australia.
    Danawi, Hadi
    Walden Univ, Minneapolis, MN USA.
    De Leo, Diego
    Griffith Univ, Brisbane, Qld, Australia.
    Degenhardt, Louisa
    Univ New South Wales, Natl Drug & Alcohol Res Ctr, Sydney, NSW, Australia.
    Denno, Donna
    Univ Washington, Dept Pediat, Seattle, WA 98195 USA;Univ Washington, Dept Global Hlth, Seattle, WA 98195 USA.
    Deribe, Kebede
    Brighton & Sussex Med Sch, Brighton, E Sussex, England.
    Jarlais, Don C. Des
    Mt Sinai Beth Israel, New York, NY USA;Icahn Sch Med Mt Sinai, New York, NY 10029 USA.
    Dey, Subhojit
    Indian Inst Publ Hlth Delhi, Publ Hlth Fdn India, Gurgaon, India.
    Dharmaratne, Samath D.
    Univ Peradeniya, Dept Community Med, Fac Med, Peradeniya, Sri Lanka.
    Djalalinia, Shirin
    Minist Hlth & Med Educ, Undersecretary Res & Technol, Tehran, Iran.
    Erskine, Holly E.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA;Univ Queensland, Sch Publ Hlth, Brisbane, Qld, Australia;Queensland Ctr Mental Hlth Res, Brisbane, Qld, Australia.
    Fereshtehnejad, Seyed-Mohammad
    Karolinska Inst, Dept Neurobiol Care Sci & Soc NVS, Stockholm, Sweden.
    Ferrari, Alize J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA;Univ Queensland, Sch Publ Hlth, Brisbane, Qld, Australia;Queensland Ctr Mental Hlth Res, Brisbane, Qld, Australia.
    Fischer, Florian
    Bielefeld Univ, Sch Publ Hlth, Bielefeld, Germany.
    Gebrehiwot, Tsegaye Tewelde
    Jimma Univ, Jimma, Ethiopia.
    Geleijnse, Johanna M.
    Wageningen Univ, Div Human Nutr, Wageningen, Netherlands.
    Gona, Philimon N.
    Univ Massachusetts, Boston, MA 02125 USA.
    Gugnani, Harish Chander
    St James Sch Med, Dept Microbiol, Melbourne, Vic, Australia;St James Sch Med, Dept Epidemiol & Biostat, Melbourne, Vic, Australia.
    Gupta, Rajeev
    Eternal Heart Care Ctr & Res Inst, Jaipur, Rajasthan, India.
    Hamadeh, Randah Ribhi
    Arabian Gulf Univ, Manama, Bahrain.
    Hamidi, Samer
    Hamdan Bin Mohammed Smart Univ, Dubai, U Arab Emirates.
    Maria Haro, Josep
    Parc Sanitari St Joan de Deu GIBERSAM, Sant Boi De Llobregat, Spain.
    Hay, Roderick J.
    Int Fdn Dermatol London, London, England;Kings Coll London, London, England.
    Hearps, Stephen J. C.
    Murdoch Childrens Res Hosp, Child Neuropsychol, Parkville, Vic, Australia.
    Hendrie, Delia
    Curtin Univ, Ctr Populat Hlth Res, Bentley, WA, Australia.
    Hotez, Peter J.
    Baylor Univ, Coll Med, Houston, TX 77030 USA.
    Hu, Guoqing
    Cent S Univ, Sch Publ Hlth, Dept Epidemiol & Hlth Stat, Changsha, Hunan, Peoples R China.
    Jonas, Jost B.
    Heidelberg Univ, Med Fac Mannheim, Dept Ophthalmol, Mannheim, Germany.
    Karch, Andre
    Helmholtz Ctr Infect Res, Epidemiol & Stat Methods Res Grp, Braunschweig, Germany;German Ctr Infect Res, Hannover Braunschweig Site, Braunschweig, Germany.
    Karimi, Seyed M.
    Univ Washington Tacoma, Tacoma, WA USA.
    Kasaeian, Amir
    Univ Tehran Med Sci, Hematol Oncol & Stem Cell Transplantat Res Ctr, Tehran, Iran;Univ Tehran Med Sci, Endocrinol & Metab Populat Sci Inst, Tehran, Iran.
    Kebede, Seifu
    Univ Addis Ababa, Sch Publ Hlth, Addis Ababa, Ethiopia;Mekelle Univ, Mekele, Ethiopia.
    Kengne, Andre Pascal
    South African Med Res Council, Cape Town, South Africa;Univ Cape Town, Cape Town, South Africa.
    Khan, Ejaz Ahmad
    Hlth Serv Acad, Islamabad, Pakistan.
    Khosravi, Ardeshir
    Iranian Minist Hlth & Med Educ, Tehran, Iran;Univ Tehran Med Sci, Noncommunicable Dis Res Ctr, Tehran, Iran.
    Khubchandani, Jagdish
    Ball State Univ, Dept Nutr & Hlth Sci, Muncie, IN 47306 USA.
    Kokubo, Yoshihiro
    Natl Cerebral & Cardiovasc Ctr, Dept Prevent Cardiol, Suita, Osaka, Japan.
    Kopec, Jacek A.
    Univ British Columbia, Vancouver, BC, Canada.
    Kosen, Soewarta
    Natl Inst Hlth Res & Dev, Ctr Community Empowerment Hlth Policy & Humanitie, Jakarta, Indonesia.
    Larson, Heidi J.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA;London Sch Hyg & Trop Med, Dept Infect Dis Epidemiol, London, England.
    Larsson, Anders
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Chemistry.
    Leasher, Janet L.
    Nova Southeastern Univ, Coll Optometry, Ft Lauderdale, FL USA.
    Leung, Janni
    Univ Washington, Seattle, WA 98195 USA.
    Li, Yongmei
    San Francisco VA Med Ctr, San Francisco, CA USA.
    Lotufo, Paulo A.
    Univ Sao Paulo, Sao Paulo, Brazil.
    Lunevicius, Raimundas
    Aintree Univ Hosp Natl Hlth Serv Fdn Trust, Liverpool, Merseyside, England;Univ Liverpool, Sch Med, Liverpool, Merseyside, England.
    Abd El Razek, Hassan Magdy
    Mansoura Fac Med, Mansoura, Egypt.
    Majdzadeh, Reza
    Univ Tehran Med Sci, Knowledge Utilizat Res Ctr & Community Based Part, Tehran, Iran.
    Majeed, Azeem
    Imperial Coll London, Dept Primary Care & Publ Hlth, London, England.
    Memiah, Peter
    Univ Florida, Pensacola, FL USA.
    Memish, Ziad A.
    Saudi Minist Hlth, Riyadh, Saudi Arabia;Alfaisal Univ, Coll Med, Riyadh, Saudi Arabia.
    Mendoza, Walter
    United Nations Populat Fund, Lima, Peru.
    Mhimbira, Francis Apolinary
    Ifakara Hlth Inst, Bagamoyo, Tanzania.
    Miller, Ted R.
    Pacific Inst Res Evaluat, Calverton, MD USA;Curtin Univ, Ctr Populat Hlth, Perth, WA, Australia.
    Mitchell, Philip B.
    Univ New South Wales, Kensington, NSW, Australia.
    Monasta, Lorenzo
    Inst Maternal & Child Hlth Burlo Garofolo, Trieste, Italy.
    Obermeyer, Carla Makhlouf
    Amer Univ Beirut, Ctr Res Populat & Hlth, Fac Hlth Sci, Beirut, Lebanon.
    Oh, In-Hwan
    Kyung Hee Univ, Sch Med, Dept Prevent Med, Seoul, South Korea.
    Olusanya, Bolajoko Olubukunola
    Ctr Hlth Start Initiat, Lagos, Nigeria.
    Ortiz, Alberto
    IIS Fdn Jimenez Diaz UAM, Madrid, Spain.
    Park, Eun-Kee
    Kosin Univ, Dept Med Humanities & Social Med, Coll Med, Busan, South Korea.
    Parry, Matti
    WHO, Reprod Hlth & Res Adolescents & Rsk Populat RHR A, Geneva, Switzerland.
    Pereira, David M.
    Univ Porto, Dept Quim, Lab Farmacognosia, REQUIMTE LAQV,Fac Farm, Porto, Portugal.
    Phillips, Michael Robert
    Shanghai Jiao Tong Univ, Sch Med, Shanghai, Peoples R China;Emory Univ, Atlanta, GA 30322 USA.
    Pourmalek, Farshad
    Univ British Columbia, Vancouver, BC, Canada.
    Qorbani, Mostafa
    Alborz Univ Med Sci, Noncommunicable Dis Res Ctr, Karaj, Iran.
    Radfar, Amir
    AT Still Univ, Kirksville, MO USA.
    Rafay, Anwar
    Contech Int Hlth Consultants, Lahore, Pakistan;Contech Sch Publ Hlth, Lahore, Pakistan.
    Rahimi-Movaghar, Vafa
    Univ Tehran Med Sci, Sina Trauma & Surg Res Ctr, Tehran, Iran.
    Rai, Rajesh Kumar
    Soc Hlth & Demog Surveillance, Suri, India.
    Rana, Saleem M.
    Contech Sch Publ Hlth, Lahore, Pakistan.
    Rawaf, David Laith
    Imperial Coll London, WHO Collaborating Ctr, London, England;North Hampshire Hosp, Basingstroke, England;Univ Coll London Hosp, London, England.
    Rawaf, Salman
    Imperial Coll London, London, England.
    Reavley, Nicola
    Univ Melbourne, Melbourne Sch Populat & Global Hlth, Melbourne, Vic, Australia.
    Renzaho, Andre M. N.
    Western Sydney Univ, Penrith, NSW, Australia.
    Rezaei, Satar
    Kermanshah Univ Med Sci, Sch Publ Hlth, Kermanshah, Iran.
    Sadegh-Rezai, Mohammad
    Mazandaran Univ Med Sci ences, Infect Dis Res Ctr Focus Nosocomial Infect, Sari, Iran.
    Rios-Zertuche, Diego
    Salud Mesoamer 2015 Initiat, Panama City, Panama.
    Roshandel, Gholamreza
    Golestan Univ Med Sci, Golestan Res Ctr Gastroenterol & Hepatol, Gorgan, Iran;Univ Tehran Med Sci, Digest Dis Res Inst, Tehran, Iran.
    Rothenbacher, Dietrich
    Univ Ulm, Inst Epidemiol & Med Biometry, Ulm, Germany.
    Safdarian, Mahdi
    Univ Tehran Med Sci, Sina Trauma & Surg Res Ctr, Tehran, Iran.
    Safi, Sare
    Safiri, Saeid
    Shahid Beheshti Univ Med Sci, Ophthalm Epidemiol Res Ctr, Tehran, Iran;Maragheh Univ Med Sci, Sch Nursing & Midwifery, Dept Publ Hlth, Managerial Epidemiol Res Ctr, Maragheh, Iran.
    Sahraian, Mohammad Ali
    Univ Tehran Med Sci, Neurosci Inst, Res Ctr, Tehran, Iran.
    Salamati, Payman
    Univ Tehran Med Sci, Sina Trauma & Surg Res Ctr, Tehran, Iran.
    Samy, Abdallah M.
    Ain Shams Univ, Cairo, Egypt.
    Sanabria, Juan Ramon
    Marshall Univ, J Edwards Sch Med, Huntington, WV USA;Case Western Reserve Univ, Cleveland, OH 44106 USA.
    Santomauro, Damian
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA;Univ Queensland, Sch Publ Hlth, Brisbane, Qld, Australia;Queensland Ctr Mental Hlth Res, Brisbane, Qld, Australia.
    Sartorius, Benn
    SAMRC, UKZN Gastrointestinal Canc Res Ctr, Durban, South Africa.
    Schwebel, David C.
    Univ Alabama Birmingham, Birmingham, AL USA.
    Seedat, Soraya
    Stellenbosch Univ, Cape Town, South Africa.
    Sepanlou, Sadaf G.
    Univ Tehran Med Sci, Digest Dis Res Inst, Tehran, Iran.
    Setegn, Tesfaye
    Bahir Dar Univ, Bahir Dar, Ethiopia.
    Shaheen, Amira
    An Najah Univ, Dept Publ Hlth, Nablus, Palestine.
    Shaikh, Masood Ali
    Shiri, Rahman
    Univ Helsinki, Finnish Inst Occupat Hlth, Fac Med, Dept Publ Hlth,Work Org,Work Diabil Program, Helsinki, Finland.
    Sigfusdottir, Inga Dora
    Reykjavik Univ, Reykjavik, Iceland.
    Singh, Jasvinder A.
    Univ Alabama Birmingham, Birmingham Vet Affairs Med Ctr, Birmingham, AL USA.
    Sobaih, Badr H. A.
    King Saud Univ, Riyadh, Saudi Arabia.
    Sreeramareddy, Chandrashekhar T.
    Int Med Univ, Dept Community Med, Kuala Lumpur, Malaysia.
    Abdulkader, Rizwan Suliankatchi
    Minist Hlth, Riyadh, Saudi Arabia.
    Tehrani-Banihashemi, Arash
    Iran Univ Med Sci, Prevent Med & Publ Hlth Res Ctr, Tehran, Iran.
    Temsah, Mohamad-Hani
    King Saud Univ, Riyadh, Saudi Arabia.
    Terkawi, Abdullah Sulieman
    Univ Virginia, Dept Anesthesiol, Charlottesville, VA USA;King Fahad Med City, Dept Anesthesiol, Riyadh, Saudi Arabia;Cleveland Clin, Outcomes Res Consortium, Cleveland, OH USA.
    Thomson, Alan J.
    Adapt Knowledge Management, Victoria, BC, Canada.
    Tonelli, Marcello
    Univ Calgary, Calgary, AB, Canada.
    Topor-Madry, Roman
    Jagiellonian Univ Med Coll, Inst Publ Hlth, Fac Hlth Sci, Krakow, Poland;Wroclaw Med Univ, Fac Hlth Sci, Wroclaw, Poland.
    Tran, Bach Xuan
    Johns Hopkins Univ, Baltimore, MD USA;Hanoi Med Univ, Hanoi, Vietnam.
    Ukwaja, Kingsley Nnanna
    Fed Teaching Hosp, Dept Internal Med, Abakaliki, Nigeria.
    Uthman, Olalekan A.
    Univ Warwick, Warwick Med Sch, Coventry, W Midlands, England.
    Vasankari, Tommi
    UKK Inst Hlth Promot Res, Tampere, Finland.
    Venketasubramanian, Narayanaswamy
    Raffles Hosp, Raffles Neurosci Ctr, Singapore, Singapore.
    Vlassov, Vasiliy Victorovich
    Natl Res Univ Higher Sch Econ, Moscow, Russia.
    Vollset, Stein Emil
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA;Norwegian Inst Publ Hlth, Ctr Dis Burden, Bergen, Norway;Univ Bergen, Dept Global Publ Hlth & Primary Care, Bergen, Norway.
    Weiderpass, Elisabete
    Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden;Canc Registry Norway, Inst Populat Based Canc Res, Dept Res, Oslo, Norway;Univ Tromso, Arctic Univ Norway, Dept Community Med, Fac Hlth Sci, Tromso, Norway;Folkhalsan Res Ctr, Genet Epidemiol Grp, Helsinki, Finland.
    Weintraub, Robert G.
    Univ Melbourne, Melbourne, Vic, Australia;Royal Childrens Hosp, Melbourne, Vic, Australia;Murdoch Childrens Res Inst, Melbourne, Vic, Australia.
    Werdecker, Andrea
    Fed Inst Populat Res, Competence Ctr Mortal Follow Up German Natl Cohor, Wiesbaden, Germany.
    Whiteford, Harvey A.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA;Univ Queensland, Sch Publ Hlth, Brisbane, Qld, Australia;Queensland Ctr Mental Hlth Res, Brisbane, Qld, Australia.
    Yano, Yuichiro
    Northwestern Univ, Dept Prevent Med, Chicago, IL 60611 USA.
    Yaseri, Mehdi
    Shahid Beheshti Univ Med Sci, Ophthalm Epidemiol Res Ctr, Tehran, Iran;Univ Tehran Med Sci, Tehran, Iran.
    Yonemoto, Naohiro
    Kyoto Univ, Sch Publ Hlth, Dept Biostat, Kyoto, Japan.
    Younis, Mustafa Z.
    Jackson State Univ, Jackson, MS USA.
    Yu, Chuanhua
    Wuhan Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Wuhan, Hubei, Peoples R China;Wuhan Univ, Global Hlth Inst, Wuhan, Hubei, Peoples R China.
    Jumaan, Aisha O.
    Vos, Theo
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Hay, Simon I.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA;Univ Oxford, Oxford Big Data Inst, Li Ka Shing Ctr Hlth Informat & Discovery, Oxford, England.
    Naghavi, Mohsen
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Patton, George C.
    Univ Melbourne, Murdoch Childrens Res Inst, Dept Paediat, Melbourne, Vic, Australia.
    Murray, Christopher J. L.
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA.
    Adolescent health in the Eastern Mediterranean Region: findings from the global burden of disease 2015 study2018In: International Journal of Public Health, ISSN 1661-8556, E-ISSN 1661-8564, Vol. 63, p. 79-96Article in journal (Refereed)
    Abstract [en]

    The 22 countries of the East Mediterranean Region (EMR) have large populations of adolescents aged 10-24 years. These adolescents are central to assuring the health, development, and peace of this region. We described their health needs. Using data from the Global Burden of Disease Study 2015 (GBD 2015), we report the leading causes of mortality and morbidity for adolescents in the EMR from 1990 to 2015. We also report the prevalence of key health risk behaviors and determinants. Communicable diseases and the health consequences of natural disasters reduced substantially between 1990 and 2015. However, these gains have largely been offset by the health impacts of war and the emergence of non-communicable diseases (including mental health disorders), unintentional injury, and self-harm. Tobacco smoking and high body mass were common health risks amongst adolescents. Additionally, many EMR countries had high rates of adolescent pregnancy and unmet need for contraception. Even with the return of peace and security, adolescents will have a persisting poor health profile that will pose a barrier to socioeconomic growth and development of the EMR.

  • Public defence: 2018-10-19 10:15 D3, Stockholm
    Du, Rong
    KTH, School of Electrical Engineering and Computer Science (EECS), Network and Systems engineering.
    Optimal Networking in Wirelessly Powered Sensor Networks2018Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    Wireless sensor networks (WSNs) are nowadays widely used for the long-term monitoring of small or large regions, such as lakes, forests, cities, and industrial areas. The performance of a WSN typically consists of two aspects: i) the monitoring performance, e.g., the accuracy and the timeliness of the measurements or estimations produced by the sensor nodes of the WSN; and ii) the lifetime, i.e., how long the WSN can sustain such a performance. Naturally, we would like to have the monitoring performance as good as possible, and the lifetime as long as possible. However, in traditional WSNs, the sensor nodes generally have limited resources, especially in terms of battery capacity. If the nodes make measurements and report them frequently for a good monitoring performance, they drain their batteries and  this leads to a severely shortened network lifetime. Conversely, the sensors can have a longer lifetime by sacrificing the monitoring performance. It shows the inherent trade-off between the monitoring performance and the lifetime in WSNs.

    We can overcome the limitations of the trade-off described above by wireless energy transfer (WET), where we can provide the sensor nodes with additional energy remotely. The WSNs with WET are called wirelessly powered sensor networks (WPSNs). In a WPSN, dedicated energy sources, e.g., static base stations or mobile chargers, transmit energy via radio frequency (RF) waves to the sensor nodes. The nodes can store the energy in their rechargeable batteries and use it later when it is needed. In so doing, they can use more energy to perform the sensing tasks. Thus, WET is a solution to improve the monitoring performance and lifetime at the same time.  As long as the nodes receive more energy than they consume, it is possible that the WSN be immortal, which is impossible in traditional WSNs. 

    Although WPSNs can potentially break the trade-off between monitoring performance and lifetime, they also bring many fundamental design and performance analysis challenges. Due to the safety issues, the power that the dedicated energy sources can use is limited. The propagation of the RF waves suffers high path losses. Therefore, the energy received by the sensor nodes is much less than the energy transmitted from the sources. As a result, to have a good WSN performance, we should optimize the energy transmission on the energy source side and the energy consumption on the nodes side. Compared to the traditional WSN scenarios where we can only optimize the sensing and data communication strategies, in WPSNs, we have an additional degree of freedom, i.e., the optimization of the energy transmission strategies. This aspect brings new technical challenges and problems that have not been studied in the traditional WSNs. Several novel research questions arise, such as when and how to transmit the energy, and which energy source should transmit. Such questions are not trivial especially when we jointly consider the energy consumption part.

    This thesis contributes to answer the questions above. It consists of three contributions as follows.

    In the first contribution, we consider a WPSN with single energy base stations (eBS) and multiple sensor nodes to monitor several separated areas of interest. The eBS has multiple antennas, and it uses energy beamforming to transmit energy to the nodes. Notice that, if we deploy multiple sensor nodes at the same area, these nodes may receive the energy from the eBS at the same time and they can reduce the energy consumption by applying sleep/awake mechanism. Therefore, we jointly study the deployment of the nodes, the energy transmission of the eBS, and the node activation. The problem is an integer optimization, and we decouple the problem into a node deployment problem and a scheduling problem. We provide a greedy-based algorithm to solve the problem, and show its performance in terms of optimality.

    The second contribution of the thesis starts by noticing that wireless channel state information (CSI) is important for energy beamforming. The more energy that an eBS spends in channel acquisition, the more accurate CSI it will have, thus improving the energy beamforming performance. However, if the eBS spends too much energy on channel acquisition, it will have less energy for WET, which might reduce the energy that is received by the sensor nodes. We thus investigate how much energy the eBS should spend in channel acquisition, i.e., we study the power allocation problem in channel acquisition and energy beamforming for WPSNs. We consider the general optimal channel acquisition and show that the problem is non-convex. Based on the idea of bisection search, we provide an algorithm to find the optimal solution for the single eBS cases, and a closed-form solution for the case where the eBS uses orthogonal pilot transmission, least-square channel estimation, and maximum ratio transmission for WET. The simulations show that the algorithm converges fast, and the performance is close to the theoretical upper bound.

    In the third contribution, we consider a joint energy beamforming and data routing problem for WPSNs. More specifically, we investigate the WPSNs consisting of multiple eBSs, multiple sensor nodes, and a sink node. Based on the received energy, the sensor nodes need to decide how to route their data. The problem aims at maximizing the minimum sensing rate of the sensor nodes while guaranteeing that the received energy of each node is no less than that is consumed. Such a problem is non-convex, and we provide a centralized solution algorithm based on a semi-definite programming transformation. We extend this approach with a distributed algorithm using alternating direction method of multipliers (ADMM). We prove that the centralized algorithm achieves the optimal energy beamforming and routing, and we show by simulation that the distributed one converges to the optimal solution. Additionally, for the cases where the energy beamforming options are pre-determined, we study the problem of finding the energy that should be spent on each vector. We observe that, if the pre-determined beamforming options are chosen wisely, their performance is close to the optimal.

    The results of the thesis show that WET can prolong the lifetime of WSNs, and even make them work sufficiently long for general monitoring applications. More importantly, we should optimize the WPSN by considering both the energy provision and the energy consumption part. The studies of the thesis have the potential to be used in many Internet of Things (IoT) systems in smart cities, such as water distribution lines and building monitoring.

  • He, Yang-Hui
    et al.
    Univ Oxford, Merton Coll, Oxford OX1 4JD, England;Nankai Univ, Sch Phys, Tianjin 300071, Peoples R China;City Univ London, Dept Math, London EC1V 0HB, England.
    Seong, Rak-Kyeong
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Department of Physics and Astronomy, Theoretical Physics.
    Yau, Shing-Tung
    Harvard Univ, Dept Math, Jefferson Phys Lab, Ctr Math Sci & Applicat, Cambridge, MA 02138 USA.
    Calabi-Yau Volumes and Reflexive Polytopes2018In: Communications in Mathematical Physics, ISSN 0010-3616, E-ISSN 1432-0916, Vol. 361, no 1, p. 155-204Article in journal (Refereed)
    Abstract [en]

    We study various geometrical quantities for Calabi-Yau varieties realized as cones over Gorenstein Fano varieties, obtained as toric varieties from reflexive polytopes in various dimensions. Focus is made on reflexive polytopes up to dimension 4 and the minimized volumes of the Sasaki-Einstein base of the corresponding Calabi-Yau cone are calculated. By doing so, we conjecture new bounds for the Sasaki-Einstein volume with respect to various topological quantities of the corresponding toric varieties. We give interpretations about these volume bounds in the context of associated field theories via the AdS/CFT correspondence.

  • Olsen, Malin
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Geriatrics.
    Aguilar, Ximena
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Geriatrics.
    Sehlin, Dag
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Geriatrics.
    Fang, Xiaotian T.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Geriatrics.
    Antoni, Gunnar
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Medicinal Chemistry, Preclinical PET-MRI Platform.
    Erlandsson, Anna
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Geriatrics.
    Syvänen, Stina
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Geriatrics.
    Astroglial Responses to Amyloid-Beta Progression in a Mouse Model of Alzheimer's Disease2018In: Molecular Imaging and Biology, ISSN 1536-1632, E-ISSN 1860-2002, Vol. 20, no 4, p. 605-614Article in journal (Refereed)
    Abstract [en]

    Alzheimer's disease (AD) is a neurodegenerative disorder characterized by amyloid-beta (A beta) deposition, hyperphosphorylation of tau, and neuroinflammation. Astrocytes, the most abundant glial cell type in the nervous system, respond to neurodegenerative disorders through astrogliosis, i.e., converting to a reactive inflammatory state. The aim of this study was to investigate how in vivo quantification of astrogliosis using positron emission tomography (PET) radioligand deuterium-l-[C-11]deprenyl ([C-11]DED), binding to enzyme monoamine oxidase-B (MAO-B) which is overexpressed in reactive astrocytes during AD, corresponds to expression of glial fibrillary acidic protein (GFAP) and vimentin, i.e., two well-established markers of astrogliosis, during A beta pathology progression. APP(ArcSwe) mice (n = 37) and wild-type (WT) control mice (n = 23), 2-16-month old, were used to investigate biomarkers of astrogliosis. The radioligand, [C-11]DED, was used as an in vivo marker while GFAP, vimentin, and MAO-B were used to investigate astrogliosis and macrophage-associated lectin (Mac-2) to investigate microglia/macrophage activation by immunohistochemistry of the mouse brain. A beta and GFAP levels were also measured with ELISA in brain homogenates. The intrabrain levels of aggregated A beta and reactive astrocytes were found to be elevated in APP(ArcSwe) compared with WT mice. GFAP and vimentin expression increased with age, i.e., with A beta pathology, in the APP(ArcSwe) mice. This was not the case for in vivo marker [C-11]DED that showed elevated binding of the same magnitude in APP(ArcSwe) mice compared with WT mice at both 8 and 16 months. Further, immunohistochemistry indicated that there was limited co-expression of MAO-B and GFAP. MAO-B levels are increased early in A beta pathology progression, while GFAP and vimentin appear to increase later, most likely as a consequence of abundant A beta plaque formation. Thus, [C-11]DED is a useful PET radioligand for the detection of changes in MAO-B at an early stage of AD progression but does not measure the total extent of astrogliosis at advanced stages of A beta pathology.

  • Abdalmoaty, Mohamed R.
    et al.
    Hjalmarsson, Håkan
    KTH, Superseded Departments (pre-2005), Signals, Sensors and Systems.
    Linear Prediction Error Methods for Stochastic Nonlinear Models2018In: Automatica, ISSN 0005-1098, E-ISSN 1873-2836Article in journal (Refereed)
    Abstract [en]

    The estimation problem for stochastic parametric nonlinear dynamical models is recognized to be challenging. The main difficulty is the intractability of the likelihood function and the optimal one-step ahead predictor. In this paper, we present relatively simple prediction error methods based on non-stationary predictors that are linear in the outputs. They can be seen as extensions of the linear identification methods for the case where the hypothesized model is stochastic and nonlinear. The resulting estimators are defined by analytically tractable objective functions in several common cases. It is shown that, under certain identifiability and standard regularity conditions, the estimators are consistent and asymptotically normal. We discuss the relationship between the suggested estimators and those based on second-order equivalent models as well as the maximum likelihood method. The paper is concluded with a numerical simulation example as well as a real-data benchmark problem.

  • Sabre, Liis
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Clinical Neurophysiology.
    Maddison, Paul
    Univ Nottingham, Hosp NHS Trust, Queens Med Ctr, Dept Neurol, Nottingham, Notts, England.
    Sadalage, Girija
    Univ Nottingham, Hosp NHS Trust, Queens Med Ctr, Dept Neurol, Nottingham, Notts, England.
    Ambrose, Philip Alexander
    Univ Nottingham, Hosp NHS Trust, Queens Med Ctr, Dept Neurol, Nottingham, Notts, England.
    Rostedt Punga, Anna
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Clinical Neurophysiology.
    Circulating microRNA miR-21-5p, miR-150-5p and miR-30e-5p correlate with clinical status in late onset myasthenia gravis2018In: Journal of Neuroimmunology, ISSN 0165-5728, E-ISSN 1872-8421, Vol. 321, p. 164-170Article in journal (Refereed)
    Abstract [en]

    There are no biomarkers for late onset myasthenia gravis (LOMG; onset > 50 years). We evaluated circulating microRNA in a discovery cohort of 4 LOMG patients and 4 healthy controls and in a prospective diagnostic validation cohort of 73 LOMG patients (48 male) with longitudinal follow-up samples. In immunosuppression naive patients, levels of miRNAs miR-150-5p, miR-21-5p and miR-30e-5p decreased in parallel with clinical improvement after initiation of immunosuppression and their levels positively correlated with the clinical MG composite score. Levels of miR-150-5p and miR-21-5p were lower in patients with ocular compared to generalized LOMG. Circulating miR-150-5p, miR-21-5p and miR-30e-5p correlate with the clinical course in LOMG.

  • Public defence: 2018-10-13 10:00 Hörsal 2, Ekonomikum, Uppsala
    Widmalm, Hedvig
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Social Sciences, Department of Economic History.
    Exploring the Mores of Mining: The oeconomy of the Great Copper Mine, 1716–17242018Doctoral thesis, monograph (Other academic)
    Abstract [en]

    This thesis closely examines the Great Copper Mine in Falun in the first two decades of the eighteenth century. It uses a micro-historical approach to investigate the economic discourse of agrarian oeconomy, a complex idea tied to the early modern agrarian society. The implementation of a series of economic reforms in 1716 and the subsequent Royal Commission in 1724 form the key sources studied here. Part of this also includes a close reading of the words of Anders Swab, the Mine Inspector, and those who argued against his reforms.

    The first three chapters introduce the methods and theories. Chapter 4 concerns the discussions surrounding the reforms. This chapter is based on the protocols of the Board of Mines, the Swedish body for governing mines and metalworks. Although the chapter uses primary source material, it provides context for understanding the materials of the Royal Commission of 1724.

    The investigation of the Royal Commission is at the centre this study. The Commission was started due to a series of petitions that were sent to the Swedish Diet by the people of Falun in 1723. The Diet then created a commission, whose officials read petitions, and collected information relating to the complaints. After this material was reviewed, the commissioners called the various groups who had petitioned, and questioned them about their complaints. They also confronted Swab, the architect behind the reforms, with their findings. Through a close reading of the petitions, the associated material, and the protocols of the Commission, this thesis investigates how groups on various levels of hierarchy discussed oeconomy. The unique social structure of the Great Copper Mine meant that it was difficult to implement the economic ideals of agrarian oeconomy. The results show how economic discourse changed depending on the status of actors in the household economy, as well as how the actors were able to use their status to further their causes. The micro-historical perspective illuminates how complex, yet contradictory the structure of the household economy was. It was meant to uphold a static hierarchy, yet it still granted a relative agency to disempowered groups within it.

  • Herberthson, Magnus
    et al.
    Linköping University, Department of Mathematics, Mathematics and Applied Mathematics. Linköping University, Faculty of Science & Engineering.
    Johansson, KarinLinköping University, Department of Mathematics. Linköping University, Faculty of Science & Engineering.Kozlov, VladimirLinköping University, Department of Mathematics, Mathematics and Applied Mathematics. Linköping University, Faculty of Science & Engineering.Ljungkvist, EmmaLinköping University, National Supercomputer Centre (NSC).Singull, MartinLinköping University, Department of Mathematics, Mathematical Statistics . Linköping University, Faculty of Science & Engineering.
    Proceedings from Workshop: Mathematics in Biology and Medicine, 11-12 May 2017, Linköping University2017Conference proceedings (editor) (Refereed)
  • Wu, Jiyue
    et al.
    Queen Mary Univ London, Sch Engn & Mat Sci, Mile End Rd, London E1 4NS, England.
    Mahajan, Amit
    Queen Mary Univ London, Sch Engn & Mat Sci, Mile End Rd, London E1 4NS, England.
    Riekehr, Lars
    Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Solid State Electronics.
    Zhang, Hangfeng
    Queen Mary Univ London, Sch Biol & Chem Sci, Mile End Rd, London E1 4NS, England.
    Yang, Bin
    Univ Chester, Fac Sci & Engn, Dept Elect & Elect Engn, Thornton Sci Pk, Chester CH2 4NU, Cheshire, England.
    Meng, Nan
    Queen Mary Univ London, Sch Engn & Mat Sci, Mile End Rd, London E1 4NS, England.
    Zhang, Zhen
    Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Solid State Electronics.
    Yan, Haixue
    Queen Mary Univ London, Sch Engn & Mat Sci, Mile End Rd, London E1 4NS, England.
    Perovskite Sr-x(Bi1-xNa0.97-xLi0.03)(0.5)TiO3 ceramics with polar nano regions for high power energy storage2018In: Nano Energy, ISSN 2211-2855, E-ISSN 2211-3282, Vol. 50, p. 723-732Article in journal (Refereed)
    Abstract [en]

    Dielectric capacitors are very attractive for high power energy storage. However, the low energy density of these capacitors, which is mainly limited by the dielectric materials, is still the bottleneck for their applications. In this work, lead-free single-phase perovskite Srx(Bi1-xNa0.97-xLi0.03)(0.5)TiO3 (x = 0.30 and 0.38) bulk ceramics, prepared using solid-state reaction method, were carefully studied for the dielectric capacitor application. Polar nano regions (PNRs) were created in this material using co-substitution at A-site to enable relaxor behaviour with low remnant polarization (P-r) and high maximum polarization (P-max). Moreover, P-max was further increased due to the electric field induced reversible phase transitions in nano regions. Comprehensive structural and electrical studies were performed to confirm the PNRs and reversible phase transitions. And finally a high energy density (1.70 J/cm(3)) with an excellent efficiency (87.2%) was achieved using the contribution of field-induced rotations of PNRs and PNR-related reversible transitions in this material, making it among the best performing lead-free dielectric ceramic bulk material for high energy storage.

  • Carlsund, Åsa
    et al.
    Mid Sweden University, Faculty of Human Sciences, Department of Nursing Sciences.
    Söderberg, Siv
    Mid Sweden University, Faculty of Human Sciences, Department of Nursing Sciences.
    Daily Life with Type 1 Diabetes from the Perspectives of Young Adults and Their Close Relatives2018In: American Journal of Nursing Science, ISSN 2328-5745, Vol. 7, no 4, p. 115-120Article in journal (Refereed)
    Abstract [en]

    The aim of this study was to enhance a deeper understanding of daily life as experienced by young adults with Type 1 Diabetes and their close relatives. Young adulthood is commonly considered as an amendment to adult roles. Increased responsibility, such as a long-term illness in young adulthood, might lead to increased stress and anxiety. Type 1 Diabetes involves large obligations related to self-care, and close relatives might play an important role in managing daily life. A hermeneutic study involving interviews with a narrative approach with couples. The hermeneutic analysis revealed that T1D is always unconditionally present in daily life for young adults and their close relatives. Close relatives are important supporters, they have an understanding based on sharing daily life with the young adults with T1D. Young adults and their close relatives highlighted the experiences of being questioned, which in turn threatens the young adults’ integrity.

  • Harvesting Bold Solutions: Ten takeaways from the Policy Lab ”Serving-Up Solutions for Agenda 2030” at the UN HLPF2018Other (Other (popular science, discussion, etc.))
    Abstract [en]

    The clock is ticking and 2030 is just around the corner. Globally, more and more people are questioning whether we can reach the SDGs and the Paris Agreement without addressing unsustainable and unhealthy food consumption patterns. Can gastronomy and food culture change offer new approaches to achieving Agenda 2030? This is precisely the question that the Government of Sweden and the Nordic Food Policy Lab asked at the dialogue Serving-Up Solutions to Agenda 2030: Food as a Golden Opportunity, during the 2018 High-level Political Forum in New York.

  • Public defence: 2018-10-12 09:00 Rosénsalen, Uppsala
    Karakatsanis, Andreas
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences.
    Sentinel Node Biopsy for Breast Cancer: Aspects and evolution2018Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    Sentinel Node Biopsy (SNB) in clinical practice was pivotal to the shaping of modern diagnosis, staging and treatment of patients with breast cancer. The use of radioisotope (RI) and blue dye (BD) has led to high detection rates with low false negatives, but delivery-of-care limitations connected to these tracers as well as the need for methods addressing new clinical conundrums delineates the urge for new tracers with comparable performance, easier logistics and, ideally expanded implementations. Aim of the present thesis is to examine the outcomes of Superparamagnetic Iron Oxide (SPIO) nanoparticles, a new tracer based on magnetism for the detection of the sentinel nodes.

    Paper I is a prospective multicentre trial comparing SPIO to RI+BD, with all tracers injected at the same patient. In 206 patients, SPIO had a similar detection rate (97.6 vs 97.1%, p=0.76) whereas concordance between methods was 98%. The study was completed by a meta-analysis of similar trials published until that point. The detection rates were comparable (fixed OR:1.10; 0.67,1.79, p=0.71), and so was concordance between tracers (fixed RD: 0.00; -0.01, 0.01, p=0.82). Discoloration was present after periareolar SPIO injection in 39% of patients, almost exclusively treated with breast conservation, which reduced to 8.6% after 15 months of follow-up.

    Paper II was a pilot study of twelve patients with breast cancer and SNB performed where SPIO and the combination of RI+BD were injected, but SPIO was injected up to 15 days preoperatively, with total success in detection and complete concordance.

    Paper III tested the performance of SPIO as a sole tracer in a pragmatic double-arm non-randomised trial comparing it to the combination of RI+BD. Detection was 95.7% for SPIO and 96.8% for RI (p = 0.59). The preoperative injection of SPIO (1-27 d) enhanced SPIO specific detection (95.7 vs 86%, p=0.002).

    Paper IV is an interim analysis of a multicentre cohort study including patients with high-risk DCIS planned for breast conservation or any DCIS planned for mastectomy. SPIO was injected to “mark” the sentinel node but SNB was performed in a second operation only if invasive cancer was found at the first operation. In 151 included patients, this technique led to avoidance of 81.5% SNB, with a cost reduction of 14.1% for the entire cohort and 25.8% for the patients that did not have invasive cancer. The detection rate at reoperation was superior for SPIO and comparable with SNB detection at primary operation.

    In conclusion, SPIO is a novel tracer for SNB in breast cancer with comparable performance, fit for performance in a global setting and with wider clinical implementations compared to RI+BD.

  • Public defence: 2018-10-18 13:15 Hörsal 12108, Gävle
    Khan, Zain Ahmed
    KTH, School of Electrical Engineering and Computer Science (EECS), Information Science and Engineering. University of Gävle.
    Characterization and Compensation of Hardware Impairments in Transmitters for Wireless Communications2018Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    Increasing demands for data rate, energy efficiency and reliability in wireless communications have resulted in the introduction of radio frequency (RF) multiple input multiple output (MIMO) transmitters. However, MIMO transmitters suffer from additional crosstalk impairments along with the power amplifier (PA) and I/Q imbalance distortions observed in single input single output (SISO) transmitters. Therefore, this thesis focuses on the characterization and compensation of these hardware impairments in RF SISO and MIMO transmitters.

    PA distortions are often compensated using the Volterra series, but it suffers from high computational complexity. Therefore, a non-parametric method based on density estimation has been proposed in this thesis to estimate the PA transfer function, from which pruned Volterra models can be developed. The method is validated for a Doherty PA and achieves competitive error performance at a lower complexity than its competitors.

    For MIMO transmitters, a characterization technique that uses multitone excitation signals has been proposed. Multitone signals yield non-overlapping tones at the outputs of the MIMO Volterra kernels. These kernel outputs are used to identify the dominant crosstalk impairments, from which block structure and base-band behavioral models are developed. The method is validated for 2x2 and 3x3 MIMO transmitters and it is shown that the derived models achieve a better complexity accuracy trade-off than the other pruned MIMO Volterra models considered in this thesis.

    Finally, the thesis presents compensation models for joint static I/Q imbalance and MIMO PA distortions based on conjugate pair and real-valued basis functions. The models are augmented with sub-sample resolution to compensate for dynamic I/Q imbalance distortions. The proposed models are validated for a 2x2 RF MIMO transmitter and achieve a better complexity accuracy trade-off than the other state-of-the-art models considered in this thesis.

  • Arvidsson, Håkan
    Swedish National Road and Transport Research Institute, Infrastructure, Pavement Technology.
    Stödremsa: laboratoriestudie av täthet och bärighet2018Report (Other academic)
    Abstract [en]

    When the support strip is not supposed to carry traffic load is low permeability considered as a more important property than bearing capacity. That is why the conclusion of this study is that moraine is more suitable for the support strip than crushed rock.

    “Support strip”: means in this report the unbound material that protects the edge of the (top) asphalt layer along (rural) roads. The support strip is quite narrow, around 30 cm (1 ft) and it should not be considered as the road shoulder.

    Some of the functions of support strips is that they should be non-permeable and have some bearing capacity. There are more functions the support strip should fulfill but in this project the properties of permeability and bearing capacity as California Bearing Capacity, CBR, have been studied in laboratory.

    The first tested material has been a granite (crushed rock) with the gradings 0/8 mm with content of fines (material < 0,063 mm), f, 8%, 10%, 15% and 20%; grading 0/11 mm with f = 10% and grading 0/16 with f equals to 8%, 10% and 15%. The second material has been a moraine with gradings 0/16 mm with f equals to 8%, 10%, 15% and 20%.

  • Jönsson, Anders
    et al.
    Kristianstad University, Faculty of Education, Research environment Learning in Science and Mathematics (LISMA). Kristianstad University, Faculty of Education, Avdelningen för matematik- och naturvetenskapernas didaktik.
    Balan, Andreia
    City of Helsingborg.
    Analytic or holistic: a study of agreement between different grading models2018In: Practical Assessment, Research & Evaluation, ISSN 1531-7714, E-ISSN 1531-7714, Vol. 23, no 12Article in journal (Refereed)
    Abstract [en]

    Research on teachers’ grading has shown that there is great variability among teachers regarding both the process and product of grading, resulting in low comparability and issues of inequality when using grades for selection purposes. Despite this situation, not much is known about the merits or disadvantages of different models for grading. In this study, a methodology for comparing two models of grading in terms of (a) agreement between assessors (reliability) and (b) justifications for the grades assigned (validity) was used with a small sample of teachers (n = 24). The design is experimental, with teachers being randomly assigned to two conditions, where they graded the same student performance using either an analytic or a holistic approach. Grades have been compared in terms of agreement and rank correlation, and justifications have been analyzed with content analysis. Findings suggest that the analytic condition yields substantively higher agreement among assessors as compared to the holistic condition (66 versus 46 percent agreement; Cohen's kappa .60 versus .41), as well as higher rank correlation (Spearman's rho .97 versus .94), without any major differences in how the grades were justified. On the contrary, there was a relatively strong consensus among most raters in the sample.

  • Karampour, Mazyar
    et al.
    KTH, School of Industrial Engineering and Management (ITM), Energy Technology, Applied Thermodynamics and Refrigeration.
    Sawalha, Samer
    KTH, School of Industrial Engineering and Management (ITM), Energy Technology, Applied Thermodynamics and Refrigeration.
    Carlos, Mateu-Royo
    ISTENER Research Group, Department of Mechanical Engineering and Construction, University Jaume I, Castellón de la Plana, Spain.
    Rogstam, Jörgen
    Energi & Kylanalys AB, Älvsjö, Sweden.
    Geothermal Storage Integration into Supermarket’s CO2 Refrigeration System2018In: Proceedings of the IGSHPA Research Track 2018, 2018Conference paper (Refereed)
    Abstract [en]

    This paper investigates the integration of geothermal storage into the state-of-the-art CO2 trans-critical booster systems. The objective is to evaluate the impact on energy efficiency of this integration. Three scenarios of integration are studied including stand-alone and integrated supermarket building systems. The results show that for a stand-alone supermarket, heat recovery from the CO2 system should be prioritized over extracting heat from the ground, which can be done either by an extra evaporator in the CO2 system or by a separate ground source heat pump. In the case of supermarket integration with a nearby district heating consumer, geothermal storage integration with extra evaporator in the CO2 refrigeration system can reduce the total annual running cost of the two buildings by 20-30%. The determining factors on profitability of geothermal storage integration are the heating demand of the supermarket and possibilities of coupling its heating system to another nearby consumer. This integration is beneficial if the full efficient heat recovery capacity of the CO2 system is not sufficient to provide the entire demands.

  • Tedersoo, Leho
    et al.
    Univ Tartu, Nat Hist Museum, 14a Ravila, EE-50411 Tartu, Estonia;Univ Tartu, Inst Ecol & Earth Sci, 14a Ravila, EE-50411 Tartu, Estonia;Estonian Young Acad Sci, 6 Kohtu, Tallinn, Estonia.
    Sanchez-Ramirez, Santiago
    Univ Toronto, Dept Ecol & Evolutionary Biol, 25 Willcocks St, Toronto, ON M5S 3B2, Canada.
    Koljalg, Urmas
    Univ Tartu, Inst Ecol & Earth Sci, 14a Ravila, EE-50411 Tartu, Estonia.
    Bahram, Mohammad
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Organismal Biology, Systematic Biology. Estonian Young Acad Sci, 6 Kohtu, Tallinn, Estonia.
    Doring, Markus
    Global Biodivers Informat Facil, Copenhagen, Denmark.
    Schigel, Dmitry
    Global Biodivers Informat Facil, Copenhagen, Denmark;Univ Helsinki, Dept Biosci, Helsinki, Finland.
    May, Tom
    Royal Bot Gardens Victoria, Birdwood Ave, Melbourne, Vic 3004, Australia.
    Ryberg, Martin
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Organismal Biology, Systematic Biology.
    Abarenkov, Kessy
    Univ Tartu, Nat Hist Museum, 14a Ravila, EE-50411 Tartu, Estonia.
    High-level classification of the Fungi and a tool for evolutionary ecological analyses2018In: Fungal diversity, ISSN 1560-2745, E-ISSN 1878-9129, Vol. 90, no 1, p. 135-159Article in journal (Refereed)
    Abstract [en]

    High-throughput sequencing studies generate vast amounts of taxonomic data. Evolutionary ecological hypotheses of the recovered taxa and Species Hypotheses are difficult to test due to problems with alignments and the lack of a phylogenetic backbone. We propose an updated phylum-and class-level fungal classification accounting for monophyly and divergence time so that the main taxonomic ranks are more informative. Based on phylogenies and divergence time estimates, we adopt phylum rank to Aphelidiomycota, Basidiobolomycota, Calcarisporiellomycota, Glomeromycota, Entomophthoromycota, Entorrhizomycota, Kickxellomycota, Monoblepharomycota, Mortierellomycota and Olpidiomycota. We accept nine subkingdoms to accommodate these 18 phyla. We consider the kingdom Nucleariae (phyla Nuclearida and Fonticulida) as a sister group to the Fungi. We also introduce a perl script and a newick-formatted classification backbone for assigning Species Hypotheses into a hierarchical taxonomic framework, using this or any other classification system. We provide an example of testing evolutionary ecological hypotheses based on a global soil fungal data set.

  • Morris, Jake
    et al.
    UCL, Dept Genet Evolut & Environm, London WC1E 6BT, England.
    Darolti, Iulia
    UCL, Dept Genet Evolut & Environm, London WC1E 6BT, England.
    Bloch, Natasha I.
    UCL, Dept Genet Evolut & Environm, London WC1E 6BT, England.
    Wright, Alison E.
    Univ Sheffield, Dept Anim & Plant Sci, Sheffield S10 2TN, S Yorkshire, England.
    Mank, Judith E.
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Organismal Biology, Systematic Biology. UCL, Dept Genet Evolut & Environm, London WC1E 6BT, England.
    Shared and Species-Specific Patterns of Nascent Y Chromosome Evolution in Two Guppy Species2018In: Genes, ISSN 2073-4425, E-ISSN 2073-4425, Vol. 9, no 5, article id 238Article in journal (Refereed)
    Abstract [en]

    Sex chromosomes form once recombination is halted around the sex-determining locus between a homologous pair of chromosomes, resulting in a male-limited Y chromosome. We recently characterized the nascent sex chromosome system in the Trinidadian guppy (Poecilia reticulata). The guppy Y is one of the youngest animal sex chromosomes yet identified, and therefore offers a unique window into the early evolutionary forces shaping sex chromosome formation, particularly the rate of accumulation of repetitive elements and Y-specific sequence. We used comparisons between male and female genomes in P. reticulata and its sister species, Endler's guppy (P. wingei), which share an ancestral sex chromosome, to identify male-specific sequences and to characterize the degree of differentiation between the X and Y chromosomes. We identified male-specific sequence shared between P. reticulata and P. wingei consistent with a small ancestral non-recombining region. Our assembly of this Y-specific sequence shows substantial homology to the X chromosome, and appears to be significantly enriched for genes implicated in pigmentation. We also found two plausible candidates that may be involved in sex determination. Furthermore, we found that the P. wingei Y chromosome exhibits a greater signature of repetitive element accumulation than the P. reticulata Y chromosome. This suggests that Y chromosome divergence does not necessarily correlate with the time since recombination suppression. Overall, our results reveal the early stages of Y chromosome divergence in the guppy.

  • Francisco, Francisco
    et al.
    Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Electricity.
    Leijon, Jennifer
    Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Electricity.
    Boström, Cecilia
    Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Electricity.
    Engström, Jens
    Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Electricity.
    Sundberg, Jan
    Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Electricity.
    Wave Power as Solution for Off-Grid Water Desalination Systems: Resource Characterization for Kilifi-Kenya2018In: Energies, ISSN 1996-1073, E-ISSN 1996-1073, Vol. 11, no 4, article id 4Article in journal (Refereed)
    Abstract [en]

    Freshwater scarcity is one of humanity's reoccurring problems that hamper socio-economic development in many regions across the globe. In coastal areas, seawater can be desalinated through reverse osmosis (RO) and transformed into freshwater for human use. Desalination requires large amounts of energy, mostly in the form of a reliable electricity supply, which in many cases is supplied by diesel generators. The objective of this work is to analyze the wave power resource availability in Kilifi-Kenya and evaluate the possible use of wave power converter (WEC) to power desalination plants. A particular focus is given use of WECs developed by Uppsala University (UU-WEC). The results here presented were achieved using reanalysis-wave data revealed that the local wave climate has an approximate annual mean of 7 kW/m and mode of 5 kW/m. Significant wave height and wave mean period are within 0.8-2 m and 7-8 s respectively, with a predominant wave mean direction from southeast. The seasonal cycle appeared to be the most relevant for energy conversion, having the highest difference of 6 kW/m, in which April is the lowest (3.8 kW/m) and August is the peak (10.5 kW/m). In such mild wave climates, the UU-WEC and similar devices can be suitable for ocean energy harvesting for water desalination systems. Technically, with a capacity factor of 30% and energy consumption of 3 kWh/m(3), a coastal community of about five thousand inhabitants can be provided of freshwater by only ten WECs with installed capacity of 20 kW.

  • Mantzouki, Evanthia
    et al.
    Univ Geneva, Dept FA Forel Environm & Aquat Sci, CH-1205 Geneva, Switzerland.
    Lurling, Miquel
    Wageningen Univ & Res, Dept Environm Sci, NL-6700 Wageningen, Netherlands;Netherlands Inst Ecol NIOO KNAW, Dept Aquat Ecol, NL-6700 Wageningen, Netherlands.
    Fastner, Jutta
    German Environm Agcy, Unit Drinking Water Resources & Water Treatment, Correnspl 1, D-14195 Berlin, Germany.
    Domis, Lisette de Senerpont
    Wageningen Univ & Res, Dept Environm Sci, NL-6700 Wageningen, Netherlands;Netherlands Inst Ecol NIOO KNAW, Dept Aquat Ecol, NL-6700 Wageningen, Netherlands.
    Wilk-Wozniak, Elzbieta
    Polish Acad Sci, Inst Nat Conservat, PL-31120 Krakow, Poland.
    Koreiviene, Judita
    Nat Res Ctr, Inst Bot, LT-08412 Vilnius, Lithuania.
    Seelen, Laura
    Wageningen Univ & Res, Dept Environm Sci, NL-6700 Wageningen, Netherlands;Netherlands Inst Ecol NIOO KNAW, Dept Aquat Ecol, NL-6700 Wageningen, Netherlands.
    Teurlincx, Sven
    Netherlands Inst Ecol NIOO KNAW, Dept Aquat Ecol, NL-6700 Wageningen, Netherlands.
    Verstijnen, Yvon
    Wageningen Univ & Res, Dept Environm Sci, NL-6700 Wageningen, Netherlands.
    Krzton, Wojciech
    Polish Acad Sci, Inst Nat Conservat, PL-31120 Krakow, Poland.
    Walusiak, Edward
    Polish Acad Sci, Inst Nat Conservat, PL-31120 Krakow, Poland.
    Karosiene, Jurate
    Nat Res Ctr, Inst Bot, LT-08412 Vilnius, Lithuania.
    Kasperoviciene, Jurate
    Nat Res Ctr, Inst Bot, LT-08412 Vilnius, Lithuania.
    Savadova, Ksenija
    Nat Res Ctr, Inst Bot, LT-08412 Vilnius, Lithuania.
    Vitonyte, Irma
    Nat Res Ctr, Inst Bot, LT-08412 Vilnius, Lithuania.
    Cillero-Castro, Carmen
    3Edata, R&D Dept Environm Engn, Lugo 27004, Spain.
    Budzynska, Agnieszka
    Adam Mickiewicz Univ, Dept Water Protect, PL-61614 Poznan, Poland.
    Goldyn, Ryszard
    Adam Mickiewicz Univ, Dept Water Protect, PL-61614 Poznan, Poland.
    Kozak, Anna
    Adam Mickiewicz Univ, Dept Water Protect, PL-61614 Poznan, Poland.
    Rosinska, Joanna
    Adam Mickiewicz Univ, Dept Water Protect, PL-61614 Poznan, Poland.
    Szelag-Wasielewska, Elzbieta
    Adam Mickiewicz Univ, Dept Water Protect, PL-61614 Poznan, Poland.
    Domek, Piotr
    Adam Mickiewicz Univ, Dept Water Protect, PL-61614 Poznan, Poland.
    Jakubowska-Krepska, Natalia
    Adam Mickiewicz Univ, Dept Water Protect, PL-61614 Poznan, Poland.
    Kwasizur, Kinga
    Adam Mickiewicz Univ, Dept Hydrobiol, PL-61614 Poznan, Poland.
    Messyasz, Beata
    Adam Mickiewicz Univ, Dept Hydrobiol, PL-61614 Poznan, Poland.
    Pelechata, Aleksandra
    Adam Mickiewicz Univ, Dept Hydrobiol, PL-61614 Poznan, Poland.
    Pelechaty, Mariusz
    Adam Mickiewicz Univ, Dept Hydrobiol, PL-61614 Poznan, Poland.
    Kokocinski, Mikolaj
    Adam Mickiewicz Univ, Dept Hydrobiol, PL-61614 Poznan, Poland.
    Garcia-Murcia, Ana
    AECOM URS, Dept Limnol & Water Qual, Barcelona 08036, Spain.
    Real, Monserrat
    AECOM URS, Dept Limnol & Water Qual, Barcelona 08036, Spain.
    Romans, Elvira
    AECOM URS, Dept Limnol & Water Qual, Barcelona 08036, Spain.
    Noguero-Ribes, Jordi
    AECOM URS, Dept Limnol & Water Qual, Barcelona 08036, Spain.
    Parreno Duque, David
    AECOM URS, Dept Limnol & Water Qual, Barcelona 08036, Spain.
    Fernandez-Moran, Elisabeth
    AECOM URS, Dept Limnol & Water Qual, Barcelona 08036, Spain.
    Karakaya, Nusret
    Abant Izzet Baysal Univ, Dept Environm Engn, TR-14280 Bolu, Turkey.
    Haggqvist, Kerstin
    Abo Akad Univ, Dept Sci & Engn, FIN-20520 Turku, Finland.
    Demir, Nilsun
    Ankara Univ, Dept Fisheries & Aquaculture, TR-6100 Ankara, Turkey.
    Beklioglu, Meryem
    Middle East Tech Univ, Dept Biol, TR-6800 Ankara, Turkey.
    Filiz, Nur
    Middle East Tech Univ, Dept Biol, TR-6800 Ankara, Turkey.
    Levi, Eti E.
    Middle East Tech Univ, Dept Biol, TR-6800 Ankara, Turkey.
    Iskin, Ugur
    Middle East Tech Univ, Dept Biol, TR-6800 Ankara, Turkey.
    Bezirci, Gizem
    Middle East Tech Univ, Dept Biol, TR-6800 Ankara, Turkey.
    Tavsanoglu, Ulku Nihan
    Middle East Tech Univ, Dept Biol, TR-6800 Ankara, Turkey.
    Ozhan, Koray
    Middle East Tech Univ, Dept Oceanog, Inst Marine Sci, TR-06800 Ankara, Turkey.
    Gkelis, Spyros
    Aristotle Univ Thessaloniki, Dept Bot, Thessaloniki 54124, Greece.
    Panou, Manthos
    Aristotle Univ Thessaloniki, Dept Bot, Thessaloniki 54124, Greece.
    Fakioglu, Ozden
    Ataturk Univ, Dept Basic Sci, TR-25240 Erzurum, Turkey.
    Avagianos, Christos
    Athens Water Supply & Sewerage Co, Water Qual Dept, Athens 11146, Greece.
    Kaloudis, Triantafyllos
    Athens Water Supply & Sewerage Co, Water Qual Dept, Athens 11146, Greece.
    Celik, Kemal
    Balikesir Univ, Dept Biol, TR-10145 Balikesir, Turkey.
    Yilmaz, Mete
    Bursa Tech Univ, Dept Bioengn, TR-16310 Bursa, Turkey.
    Marce, Rafael
    Catalan Inst Water Res ICRA, Girona 17003, Spain.
    Catalán, Núria
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics, Limnology. Catalan Inst Water Res ICRA, Girona 17003, Spain.
    Bravo, Andrea Garcia
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics, Limnology.
    Buck, Moritz
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics, Limnology.
    Colom-Montero, William
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics, Limnology.
    Mustonen, Kristiina
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics.
    Pierson, Don
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics, Limnology.
    Yang, Yang
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics.
    Raposeiro, Pedro M.
    Univ Azores, Fac Sci & Technol, InBIO Associated Lab, Res Ctr Biodivers & Genet Resources CIBIO Azores, P-9501801 Ponta Delgada, Portugal.
    Goncalves, Vitor
    Univ Azores, Fac Sci & Technol, InBIO Associated Lab, Res Ctr Biodivers & Genet Resources CIBIO Azores, P-9501801 Ponta Delgada, Portugal.
    Antoniou, Maria G.
    Cyprus Univ Technol, Dept Environm Sci & Technol, CY-3036 Lemesos, Cyprus.
    Tsiarta, Nikoletta
    Cyprus Univ Technol, Dept Environm Sci & Technol, CY-3036 Lemesos, Cyprus.
    McCarthy, Valerie
    Dundalk Inst Technol, Ctr Freshwater & Environm Studies, Dundalk A91 K584, Ireland.
    Perello, Victor C.
    Dundalk Inst Technol, Ctr Freshwater & Environm Studies, Dundalk A91 K584, Ireland.
    Feldmann, Tonu
    Estonian Univ Life Sci, Inst Agr & Environm Sci, EE-51014 Tartu, Estonia.
    Laas, Alo
    Estonian Univ Life Sci, Inst Agr & Environm Sci, EE-51014 Tartu, Estonia.
    Panksep, Kristel
    Estonian Univ Life Sci, Inst Agr & Environm Sci, EE-51014 Tartu, Estonia.
    Tuvikene, Lea
    Estonian Univ Life Sci, Inst Agr & Environm Sci, EE-51014 Tartu, Estonia.
    Gagala, Ilona
    Polish Acad Sci, European Reg Ctr Ecohydrol, PL-90364 Lodz, Poland.
    Mankiewicz-Boczek, Joana
    Polish Acad Sci, European Reg Ctr Ecohydrol, PL-90364 Lodz, Poland.
    Yagci, Meral Apaydin
    Republ Turkey Minist Food Agr, Fisheries Res Inst, TR-32500 Isparta, Turkey.
    Cinar, Sakir
    Republ Turkey Minist Food Agr, Fisheries Res Inst, TR-32500 Isparta, Turkey.
    Capkin, Kadir
    Republ Turkey Minist Food Agr, Fisheries Res Inst, TR-32500 Isparta, Turkey.
    Yagci, Abdulkadir
    Republ Turkey Minist Food Agr, Fisheries Res Inst, TR-32500 Isparta, Turkey.
    Cesur, Mehmet
    Republ Turkey Minist Food Agr, Fisheries Res Inst, TR-32500 Isparta, Turkey.
    Bilgin, Fuat
    Republ Turkey Minist Food Agr, Fisheries Res Inst, TR-32500 Isparta, Turkey.
    Bulut, Cafer
    Republ Turkey Minist Food Agr, Fisheries Res Inst, TR-32500 Isparta, Turkey.
    Uysal, Rahmi
    Republ Turkey Minist Food Agr, Fisheries Res Inst, TR-32500 Isparta, Turkey.
    Obertegger, Ulrike
    Fdn Edmund Mach, Dept Sustainable Ecosyst & Bioresources, I-38010 San Michele All Adige, Italy.
    Boscaini, Adriano
    Fdn Edmund Mach, Dept Sustainable Ecosyst & Bioresources, I-38010 San Michele All Adige, Italy.
    Flaim, Giovanna
    Fdn Edmund Mach, Dept Sustainable Ecosyst & Bioresources, I-38010 San Michele All Adige, Italy.
    Salmaso, Nico
    Fdn Edmund Mach, Dept Sustainable Ecosyst & Bioresources, I-38010 San Michele All Adige, Italy.
    Cerasino, Leonardo
    Fdn Edmund Mach, Dept Sustainable Ecosyst & Bioresources, I-38010 San Michele All Adige, Italy.
    Richardson, Jessica
    Univ Stirling, Dept Biol & Environm Sci, Stirling FK9 4LA, Scotland.
    Visser, Petra M.
    Univ Amsterdam, Dept Freshwater & Marine Ecol, NL-1090 GE Amsterdam, Netherlands.
    Verspagen, Jolanda M. H.
    Univ Amsterdam, Dept Freshwater & Marine Ecol, NL-1090 GE Amsterdam, Netherlands.
    Karan, Tunay
    Gaziosmanpasa Univ, Dept Mol Biol & Genet, TR-60250 Merkez, Turkey.
    Soylu, Elif Neyran
    Giresun Univ, Dept Biol, TR-28100 Giresun, Turkey.
    Maraslioglu, Faruk
    Hitit Univ, Dept Biol, TR-19040 Corum, Turkey.
    Napiorkowska-Krzebietke, Agnieszka
    Inland Fisheries Inst, Dept Icthyol Hydrobiol & Aquat Ecol, PL-10719 Olsztyn, Poland.
    Ochocka, Agnieszka
    Natl Res Inst, Dept Freshwater Protect, Inst Environm Protect, PL-01692 Warsaw, Poland.
    Pasztaleniec, Agnieszka
    Natl Res Inst, Dept Freshwater Protect, Inst Environm Protect, PL-01692 Warsaw, Poland.
    Antao-Geraldes, Ana M.
    Inst Politecn Braganca, Ctr Invest Montanha, Campus Santa Apolonia, P-5300253 Braganca, Portugal.
    Vasconcelos, Vitor
    Interdisciplinary Ctr Marine & Environm Res CIIMA, P-4450208 Matosinhos, Portugal;Univ Porto, P-4450208 Matosinhos, Portugal.
    Morais, Joao
    Interdisciplinary Ctr Marine & Environm Res CIIMA, P-4450208 Matosinhos, Portugal;Univ Porto, P-4450208 Matosinhos, Portugal.
    Vale, Micaela
    Interdisciplinary Ctr Marine & Environm Res CIIMA, P-4450208 Matosinhos, Portugal;Univ Porto, P-4450208 Matosinhos, Portugal.
    Koker, Latife
    Istanbul Univ, Fac Aquat Sci, Dept Freshwater Resource & Management, TR-34134 Istanbul, Turkey.
    Akcaalan, Reyhan
    Istanbul Univ, Fac Aquat Sci, Dept Freshwater Resource & Management, TR-34134 Istanbul, Turkey.
    Albay, Meric
    Istanbul Univ, Fac Aquat Sci, Dept Freshwater Resource & Management, TR-34134 Istanbul, Turkey.
    Maronic, Dubravka Spoljaric
    Josip Juraj Strossmayer Univ Osijek, Dept Biol, Osijek 31000, Croatia.
    Stevic, Filip
    Josip Juraj Strossmayer Univ Osijek, Dept Biol, Osijek 31000, Croatia.
    Pfeiffer, Tanja Zuna
    Josip Juraj Strossmayer Univ Osijek, Dept Biol, Osijek 31000, Croatia.
    Fonvielle, Jeremy
    Leibniz Inst Freshwater Ecol & Inland Fisheries, Dept Expt Limnol, D-16775 Stechlin, Germany.
    Straile, Dietmar
    Univ Konstanz, Limnol Inst, Dept Biol, D-78464 Constance, Germany.
    Rothhaupt, Karl-Otto
    Univ Konstanz, Limnol Inst, Dept Biol, D-78464 Constance, Germany.
    Hansson, Lars-Anders
    Lund Univ, Dept Biol, S-22362 Lund, Sweden.
    Urrutia Cordero, Pablo
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics, Limnology. Lund Univ, Dept Biol, S-22362 Lund, Sweden.
    Blaha, Ludek
    Masaryk Univ, RECETOX, Fac Sci, Brno 62500, Czech Republic.
    Geris, Rodan
    Morava Board Author, Dept Hydrobiol, Brno 60200, Czech Republic.
    Frankova, Marketa
    Czech Acad Sci, Inst Bot, Lab Paleoecol, Brno 60200, Czech Republic.
    Kocer, Mehmet Ali Turan
    Mediterranean Fisheries Res Prod & Training Inst, Dept Environm & Resource Management, TR-7090 Antalya, Turkey.
    Alp, Mehmet Tahir
    Mersin Univ, Fac Aquaculture, TR-33160 Mersin, Turkey.
    Remec-Rekar, Spela
    Slovenian Environm Agcy, Water Qual Dept, Ljubljana 1000, Slovenia.
    Elersek, Tina
    Natl Inst Biol, Dept Genet Toxicol & Canc Biol, Ljubljana 1000, Slovenia.
    Triantis, Theodoros
    Natl Ctr Sci Res Demokritos, Inst Nanosci & Nanotechnol, Attiki 15341, Greece.
    Zervou, Sevasti-Kiriaki
    Natl Ctr Sci Res Demokritos, Inst Nanosci & Nanotechnol, Attiki 15341, Greece.
    Hiskia, Anastasia
    Natl Ctr Sci Res Demokritos, Inst Nanosci & Nanotechnol, Attiki 15341, Greece.
    Haande, Sigrid
    Norwegian Inst Water Res, Dept Freshwater Ecol, N-0349 Oslo, Norway.
    Skjelbred, Birger
    Norwegian Inst Water Res, Dept Freshwater Ecol, N-0349 Oslo, Norway.
    Madrecka, Beata
    Poznan Univ Tech, Inst Environm Engn, PL-60965 Poznan, Poland.
    Nemova, Hana
    Publ Hlth Author Slovak Republ, Natl Reference Ctr Hydrobiol, Bratislava 82645, Slovakia.
    Drastichova, Iveta
    Publ Hlth Author Slovak Republ, Natl Reference Ctr Hydrobiol, Bratislava 82645, Slovakia.
    Chomova, Lucia
    Publ Hlth Author Slovak Republ, Natl Reference Ctr Hydrobiol, Bratislava 82645, Slovakia.
    Edwards, Christine
    Robert Gordon Univ, Sch Pharm & Life Sci, Aberdeen AB10 7GJ, Scotland.
    Sevindik, Tugba Ongun
    Sakarya Univ, Dept Biol, TR-54187 Sakarya, Turkey.
    Tunca, Hatice
    Sakarya Univ, Dept Biol, TR-54187 Sakarya, Turkey.
    OEnem, Burcin
    Sakarya Univ, Dept Biol, TR-54187 Sakarya, Turkey.
    Aleksovski, Boris
    SS Cyril & Methodius Univ, Fac Nat Sci & Math, Skopje 1000, Macedonia.
    Krstic, Svetislav
    SS Cyril & Methodius Univ, Fac Nat Sci & Math, Skopje 1000, Macedonia.
    Vucelic, Itana Bokan
    Teaching Inst Publ Hlth Primorje Gorski Kotar Cty, Dept Ecotoxicol, Rijeka 51000, Croatia.
    Nawrocka, Lidia
    State Univ Appl Sci, Inst Technol, PL-82300 Elblag, Poland.
    Salmi, Pauliina
    Univ Jyvaskyla, Dept Biol & Environm Sci, Jyvaskyla 40014, Finland.
    Machado-Vieira, Danielle
    Univ Fed Paraiba, Dept Sistemat & Ecol, BR-58059970 Joao Pessoa, Paraiba, Brazil.
    de Oliveira, Alinne Gurjao
    Univ Fed Paraiba, Dept Sistemat & Ecol, BR-58059970 Joao Pessoa, Paraiba, Brazil.
    Delgado-Martin, Jordi
    Univ A Coruna, Dept Civil Engn, La Coruna 15192, Spain.
    Garcia, David
    Univ A Coruna, Dept Civil Engn, La Coruna 15192, Spain.
    Cereijo, Jose Luis
    Univ A Coruna, Dept Civil Engn, La Coruna 15192, Spain.
    Goma, Joan
    Univ Barcelona, Dept Evolutionary Biol Ecol & Environm Sci, E-08028 Barcelona, Spain.
    Trapote, Mari Carmen
    Univ Barcelona, Dept Evolutionary Biol Ecol & Environm Sci, E-08028 Barcelona, Spain.
    Vegas-Vilarrubia, Teresa
    Univ Barcelona, Dept Evolutionary Biol Ecol & Environm Sci, E-08028 Barcelona, Spain.
    Obrador, Biel
    Univ Barcelona, Dept Evolutionary Biol Ecol & Environm Sci, E-08028 Barcelona, Spain.
    Grabowska, Magdalena
    Univ Bialystok, Dept Hydrobiol, PL-15245 Bialystok, Poland.
    Karpowicz, Maciej
    Univ Bialystok, Dept Hydrobiol, PL-15245 Bialystok, Poland.
    Chmura, Damian
    Univ Bielsko Biala, Inst Environm Protect & Engn, PL-43309 Bielsko Biala, Poland.
    Ubeda, Barbara
    Univ Cadiz, Dept Biol, Puerto Real 11510, Spain.
    Angel Galvez, Jose
    Univ Cadiz, Dept Biol, Puerto Real 11510, Spain.
    Ozen, Arda
    Univ Cankiri Karatekin, Dept Forest Engn, TR-18200 Cankiri, Turkey.
    Christoffersen, Kirsten Seestern
    Univ Copenhagen, Dept Biol, Freshwater Biol Lab, DK-2100 Copenhagen, Denmark.
    Warming, Trine Perlt
    Univ Copenhagen, Dept Biol, Freshwater Biol Lab, DK-2100 Copenhagen, Denmark.
    Kobos, Justyna
    Univ Gdansk, Dept Marine Biotechnol, PL-81378 Gdynia, Poland.
    Mazur-Marzec, Hanna
    Univ Gdansk, Dept Marine Biotechnol, PL-81378 Gdynia, Poland.
    Perez-Martinez, Carmen
    Univ Granada, Dept Ecol, E-18071 Granada, Spain.
    Ramos-Rodriguez, Eloisa
    Univ Granada, Dept Ecol, E-18071 Granada, Spain.
    Arvola, Lauri
    Univ Helsinki, Lammi Biol Stn, Lammi 16900, Finland.
    Alcaraz-Parraga, Pablo
    Univ Jaen, Dept Anim Biol Plant Biol & Ecol, Jaen 23701, Spain.
    Toporowska, Magdalena
    Univ Life Sci Lublin, Dept Hydrobiol & Protect Ecosyst, PL-20262 Lublin, Poland.
    Pawlik-Skowronska, Barbara
    Univ Life Sci Lublin, Dept Hydrobiol & Protect Ecosyst, PL-20262 Lublin, Poland.
    Niedzwiecki, Michal
    Univ Life Sci Lublin, Dept Hydrobiol & Protect Ecosyst, PL-20262 Lublin, Poland.
    Peczula, Wojciech
    Univ Life Sci Lublin, Dept Hydrobiol & Protect Ecosyst, PL-20262 Lublin, Poland.
    Leira, Manel
    Univ Lisbon, Inst Dom Luiz, P-1749016 Lisbon, Portugal.
    Hernandez, Armand
    CSIC, ICTJA, Inst Earth Sci Jaume Almera, Barcelona 08028, Spain.
    Moreno-Ostos, Enrique
    Univ Malaga, Dept Ecol, E-29071 Malaga, Spain.
    Maria Blanco, Jose
    Univ Malaga, Dept Ecol, E-29071 Malaga, Spain.
    Rodriguez, Valeriano
    Univ Malaga, Dept Ecol, E-29071 Malaga, Spain.
    Juan Montes-Perez, Jorge
    Univ Malaga, Dept Ecol, E-29071 Malaga, Spain.
    Palomino, Roberto L.
    Univ Malaga, Dept Ecol, E-29071 Malaga, Spain.
    Rodriguez-Perez, Estela
    Univ Malaga, Dept Ecol, E-29071 Malaga, Spain.
    Carballeira, Rafael
    Univ A Coruna, Fac Ciencias, CICA, La Coruna 15071, Spain.
    Camacho, Antonio
    Univ Valencia, Cavanilles Inst Biodivers & Evolutionary Biol, Paterna Valencia 46980, Spain.
    Picazo, Antonio
    Univ Valencia, Cavanilles Inst Biodivers & Evolutionary Biol, Paterna Valencia 46980, Spain.
    Rochera, Carlos
    Univ Valencia, Cavanilles Inst Biodivers & Evolutionary Biol, Paterna Valencia 46980, Spain.
    Santamans, Anna C.
    Univ Valencia, Cavanilles Inst Biodivers & Evolutionary Biol, Paterna Valencia 46980, Spain.
    Ferriol, Carmen
    Univ Valencia, Cavanilles Inst Biodivers & Evolutionary Biol, Paterna Valencia 46980, Spain.
    Romo, Susana
    Univ Valencia, Dept Microbiol & Ecol, E-46100 Burjassot, Spain.
    Miguel Soria, Juan
    Univ Valencia, Dept Microbiol & Ecol, E-46100 Burjassot, Spain.
    Dunalska, Julita
    Univ Warmia & Mazury, Dept Water Protect Engn, PL-10720 Olsztyn, Poland.
    Sienska, Justyna
    Univ Warmia & Mazury, Dept Water Protect Engn, PL-10720 Olsztyn, Poland.
    Szymanski, Daniel
    Univ Warmia & Mazury, Dept Water Protect Engn, PL-10720 Olsztyn, Poland.
    Kruk, Marek
    Univ Warmia & Mazury, Dept Tourism Recreat & Ecol, PL-10720 Olsztyn, Poland.
    Kostrzewska-Szlakowska, Iwona
    Univ Warsaw, Fac Biol, PL-02096 Warsaw, Poland.
    Jasser, Iwona
    Univ Warsaw, Dept Plant Ecol & Environm Conservat, Fac Biol, PL-02089 Warsaw, Poland.
    Zutinic, Petar
    Univ Zagreb, Dept Biol, Fac Sci, Zagreb 10000, Croatia.
    Udovic, Marija Gligora
    Univ Zagreb, Dept Biol, Fac Sci, Zagreb 10000, Croatia.
    Plenkovic-Moraj, Andelka
    Univ Zagreb, Dept Biol, Fac Sci, Zagreb 10000, Croatia.
    Frak, Magdalena
    Warsaw Univ Life Sci SGGW, Fac Civil & Environm Engn, Dept Environm Improvement, PL-02787 Warsaw, Poland.
    Bankowska-Sobczak, Agnieszka
    Warsaw Univ Life Sci SGGW, Fac Civil & Environm Engn, Dept Hydraul Engn, PL-02787 Warsaw, Poland.
    Wasilewicz, Michal
    Warsaw Univ Life Sci SGGW, Fac Civil & Environm Engn, Dept Hydraul Engn, PL-02787 Warsaw, Poland.
    Ozkan, Korhan
    Middle East Tech Univ, Inst Marine Sci Marine Biol & Fisheries, TR-06800 Ankara, Turkey.
    Maliaka, Valentini
    Wageningen Univ & Res, Dept Environm Sci, NL-6700 Wageningen, Netherlands;Soc Protect Prespa, Agios Germanos 53077, Greece;Radboud Univ Nijmegen, Dept Aquat Ecol & Environm Biol, Inst Water & Wetland Res, NL-6525 AJ Nijmegen, Netherlands.
    Kangro, Kersti
    Estonian Univ Life Sci, Inst Agr & Environm Sci, EE-51014 Tartu, Estonia;Univ Tartu, Fac Sci & Technol, Tartu Observ, EE-61602 Tartu, Estonia.
    Grossart, Hans-Peter
    Leibniz Inst Freshwater Ecol & Inland Fisheries, Dept Expt Limnol, D-16775 Stechlin, Germany;Univ Potsdam, Inst Biochem & Biol, D-14469 Potsdam, Germany.
    Paerl, Hans W.
    Univ N Carolina, Inst Marine Sci, Chapel Hill, NC 28557 USA.
    Carey, Cayelan C.
    Virginia Tech, Dept Biol Sci, Blacksburg, VA 24061 USA.
    Ibelings, Bas W.
    Univ Geneva, Dept FA Forel Environm & Aquat Sci, CH-1205 Geneva, Switzerland.
    Temperature Effects Explain Continental Scale Distribution of Cyanobacterial Toxins2018In: Toxins, ISSN 2072-6651, E-ISSN 2072-6651, Vol. 10, no 4, article id 156Article in journal (Refereed)
    Abstract [en]

    Insight into how environmental change determines the production and distribution of cyanobacterial toxins is necessary for risk assessment. Management guidelines currently focus on hepatotoxins (microcystins). Increasing attention is given to other classes, such as neurotoxins (e.g., anatoxin-a) and cytotoxins (e.g., cylindrospermopsin) due to their potency. Most studies examine the relationship between individual toxin variants and environmental factors, such as nutrients, temperature and light. In summer 2015, we collected samples across Europe to investigate the effect of nutrient and temperature gradients on the variability of toxin production at a continental scale. Direct and indirect effects of temperature were the main drivers of the spatial distribution in the toxins produced by the cyanobacterial community, the toxin concentrations and toxin quota. Generalized linear models showed that a Toxin Diversity Index (TDI) increased with latitude, while it decreased with water stability. Increases in TDI were explained through a significant increase in toxin variants such as MC-YR, anatoxin and cylindrospermopsin, accompanied by a decreasing presence of MC-LR. While global warming continues, the direct and indirect effects of increased lake temperatures will drive changes in the distribution of cyanobacterial toxins in Europe, potentially promoting selection of a few highly toxic species or strains.

  • Ederth, Thomas
    Linköping University, Department of Physics, Chemistry and Biology, Molecular Physics. Linköping University, Faculty of Science & Engineering.
    Neutrons for scattering: What they are, where to get them, and how to deal with them2018In: EPJ Web of Conferences, ISSN 2101-6275, E-ISSN 2100-014X, Vol. 188, article id 01002Article in journal (Refereed)
    Abstract [en]

    In neutron scattering studies of soft matter, a diverse array of methods and instruments are used, providing information on structure and dynamics on various length and energy scales. However, much of the infrastructure needed for neutron scattering is common for many instruments. After a brief historical retrospect of neutron scattering, this chapter introduces the basic infrastructure needed to conduct scattering experiments. This includes equipment that is used to produce, spectrally adjust and purify, and to deliver neutrons to the instruments where scattering experiments are conducted. The basics of the interaction of neutrons with matter is also introduced, as a preparation for the final sections on the different means at hand for neutron detection.

  • Osvaldsson Cromdal, Karin
    et al.
    Linköping University, Faculty of Arts and Sciences. Linköping University, Department of Social and Welfare Studies, Social Work.
    Sköld, Johanna
    Linköping University, Faculty of Arts and Sciences. Linköping University, Department of Thematic Studies, Department of Child Studies.
    En professionaliserad röst för barnen?: Förändringar i en barnrättsorganisation2018Report (Other academic)
    Abstract [sv]

    I detta projekt undersöker vi organisatoriska förändringar som BRIS – Barnets rätt isamhället – genomfört under sin drygt 40-åriga historia. Tyngdpunkten ligger på den senaste omorganisationen, där BRIS i stället för att låta hundratals volontärer ta emot barns och ungas kontakter anställde knappt tjugo så kallade BRIS-kuratorer som idag ärde som tar emot telefonsamtal, chattar och mejl. Vi jämför denna omorganisering, med tidigare organisatoriska förändringar och med de ideologiska slitningar som BRIS genomgick precis när organisationen bildades. Resultaten visar att beslutet att ”professionalisera” kontakterna under 2010-talet genom att anställa personal föregåtts av flera tidigare diskussioner om professionaliseringsbehov. Vi kan visa att tidigare professionaliseringsdiskussioner drevs främst med argument ombehov av ökad kvalitet i kontakter med unga, men att förarbetet till den senasteprofessionaliseringen hade en ytterligare komponent: ekonomiska hänsyn. Andra resultat rör de förändringar av rollerna som förbundsordförande och senare generalsekreterare haft i organisationen, samt vilka ideologiska motsättningar som funnits i organisationens historia. Slutligen undersökte vi BRIS utåtriktade arbete, genom en analys avdebattartiklar och dagspress. Framförallt intresserade vi oss för vem eller vilka som beskrevs som problembärare och/eller ansvariga för svårigheter i barns och ungaslivsvillkor. Här finner vi en tydlig förändring. Under tidigt 1970-tal är det föräldrar och barns svaga rättsliga ställning som ses som de stora problemen. De senaste tio åren harBRIS debattinlägg handlat i mycket lite grad om detta. I stället har debatten riktat in sig på samhällets offentliga verksamheter av betydelse för barn och unga, främst skola, BUP och socialtjänst och deras problem med att fullfölja sitt uppdrag.

  • Osvaldsson Cromdal, Karin
    Linköping University, Department of Social and Welfare Studies, Social Work. Linköping University, Faculty of Arts and Sciences.
    Socialrådgivning på nätet: Rapport om FoU-projekt med stöd av lokala utvecklingsmedel2018Report (Other academic)
    Abstract [sv]

    Detta projekt har haft som syfte att följa kommunikationen mellan brukare och tjänsteman via frågeformulär (mejlsvar) och chatt och undersöka dess förutsättningar det första året Socialrådgivningen på nätet var igång (maj 2013 - maj 2014).

    Arbetet har i huvudsak bestått har bestått av att sammanställa och analysera innehållet i kontakterna, både kvalitativt och kvantitativt. Innehållet i chattarna är ingående analyserat genom närläsning och tematisering av både vad deltagarna diskuterar, men också hur de gör detta. Jag har också genomfört deltagande observationer av projektmöten och arbetsmöten och i samband med dessa genomfört intervjuer med socialrådgivare.

    Under året registrerades 1529 kontakter. Resultaten1 visar att den genomsnittlige användaren uppger sig vara runt 30 år (medianålder 29, medelålder 32). Denna är oftare kvinna än man. Den vanligaste kontaktorsaken rör ekonomiskt bistånd men frågor om familjerätt bostad och relationer är också vanliga. Det är betydligt vanligare att kontakten rör vuxna än barn och unga. Rådgivningen består av både upplysning och stöd. Detta är delvis knutet till de två formerna för kontakt med socialrådgivningen som finns.

    Frågeformuläret medger endast svar på fråga medan chattarna be-står av interaktion i realtid. De senare får betydligt oftare en stöd-karaktär. Om vi tänker oss att stödjande rådgivning behöver en utvecklad dialog är det i chattarna detta finns.

    Resultaten visar också att medborgarna är nöjda med rådgivningen, både att det går fort att komma i kontakt med rådgivningen men också med den hjälp rådgivningen erbjuder.

  • Ostman, Maja Eriksson
    et al.
    Orebro Univ, Fac Hlth, Dept Cardiol, Orebro, Sweden.
    Calais, Fredrik
    Orebro Univ, Fac Hlth, Dept Cardiol, Orebro, Sweden.
    Rosenblad, Andreas
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centre for Clinical Research, County of Västmanland.
    Frobert, Ole
    Orebro Univ, Fac Hlth, Dept Cardiol, Orebro, Sweden.
    Leppert, Jerzy
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centre for Clinical Research, County of Västmanland.
    Hedberg, Pär
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centre for Clinical Research, County of Västmanland. Vastmanland Cty Hosp, Dept Clin Physiol, Vasteras, Sweden.
    Prognostic impact of subclinical or manifest extracoronary artery diseases after acute myocardial infarction2017In: Atherosclerosis, ISSN 0021-9150, E-ISSN 1879-1484, Vol. 263, p. 53-59Article in journal (Refereed)
    Abstract [en]

    Background and aims: In patients with coronary artery disease (CAD), clinically overt extracoronary artery diseases (ECADs), including claudication or previous strokes, are associated with poor outcomes. Subclinical ECADs detected by screening are common among such patients. We aimed to evaluate the prognostic impact of subclinical versus symptomatic ECADs in patients with acute myocardial infarction (AMI). Methods: In a prospective observational study, 654 consecutive patients diagnosed with AMI underwent ankle brachial index (ABI) measurements and ultrasonographic screening of the carotid arteries and abdominal aorta. Clinical ECADs were defined as prior strokes, claudication, or extracoronary artery intervention. Subclinical ECADs were defined as the absence of a clinical ECAD in combination with an ABI <= 0.9 or >1.4, carotid artery stenosis, or an abdominal aortic aneurysm. Results: At baseline, subclinical and clinical ECADs were prevalent in 21.6% and 14.4% of the patients, respectively. Patients with ECADs received evidence-based medication more often at admission but similar medications at discharge compared with patients without ECADs. During a median follow-up of 5.2 years, 166 patients experienced endpoints of hospitalization for AMI, heart failure, stroke, or cardiovascular death. With ECAD-free cases as reference and after adjustment for risk factors, a clinical ECAD (hazard ratio [HR] 2.10, 95% confidence interval [CI] 1.34-3.27, p = 0.001), but not a subclinical ECAD (HR 1.35, 95% CI 0.89-2.05, p = 0.164), was significantly associated with worse outcomes. Conclusions: Despite receiving similar evidence-based medication at discharge, patients with clinical ECAD, but not patients with a subclinical ECAD, had worse long-term prognosis than patients without an ECAD after AMI.

  • Crowe-McAuliffe, Caillan
    et al.
    Graf, Michael
    Huter, Paul
    Takada, Hiraku
    Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine). Umeå University, Faculty of Medicine, Molecular Infection Medicine Sweden (MIMS).
    Abdelshahid, Maha
    Novácek, Jirí
    Murina, Victoriia
    Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine).
    Atkinson, Gemma C.
    Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine).
    Hauryliuk, Vasili
    Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine). Umeå University, Faculty of Medicine, Molecular Infection Medicine Sweden (MIMS). Institute of Technology, University of Tartu, 50411 Tartu, Estonia.
    Wilson, Daniel N.
    Structural basis for antibiotic resistance mediated by the Bacillus subtilis ABCF ATPase VmlR2018In: Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, E-ISSN 1091-6490, Vol. 115, no 36, p. 8978-8983Article in journal (Refereed)
    Abstract [en]

    Many Gram-positive pathogenic bacteria employ ribosomal protection proteins (RPPs) to confer resistance to clinically important antibiotics. In Bacillus subtilis, the RPP VmlR confers resistance to lincomycin (Lnc) and the streptogramin A (SA) antibiotic virginiamycin M (VgM). VmlR is an ATP-binding cassette (ABC) protein of the F type, which, like other antibiotic resistance (ARE) ABCF proteins, is thought to bind to antibiotic-stalled ribosomes and promote dissociation of the drug from its binding site. To investigate the molecular mechanism by which VmlR confers antibiotic resistance, we have determined a cryo-electron microscopy (cryo-EM) structure of an ATPase-deficient B. subtilis VmlR-EQ(2) mutant in complex with a B. subtilis ErmDL-stalled ribosomal complex (SRC). The structure reveals that VmlR binds within the E site of the ribosome, with the antibiotic resistance domain (ARD) reaching into the peptidyltransferase center (PTC) of the ribosome and a C-terminal extension (CTE) making contact with the small subunit (SSU). To access the PTC, VmlR induces a conformational change in the P-site tRNA, shifting the acceptor arm out of the PTC and relocating the CCA end of the P-site tRNA toward the A site. Together with microbiological analyses, our study indicates that VmlR allosterically dissociates the drug from its ribosomal binding site and exhibits specificity to dislodge VgM, Lnc, and the pleuromutilin tiamulin (Tia), but not chloramphenicol (Cam), linezolid (Lnz), nor the macrolide erythromycin (Ery).

  • Bugge, Heidi Belinda
    et al.
    Nicolaisen, Karl-Oskar
    Ecolabelled Textiles in the Nordic Countries: Promoting the supply of textiles ecolabelled with the official ecolabels - English Summary to Nordic Working Paper2018Report (Other academic)
    Abstract [en]

    The textile industry is one of the world's largest industries. The fashion and textile industry is also one of the most polluting and resource-consuming industries in the world. Ecolabels such as the Nordic Swan Ecolabel and the EU Ecolabel can play an important role in reducing the environmental impact of textiles purchased in Nordic countries. The project aims to identify barriers to more ecolabelled textiles on the Nordic consumer market and initiate activities and actions to remedy these. The project has also taken a global perspective, identifying how producers in e.g. India and Turkey can be encouraged to engage in eco-labelling. The study was financed by the Nordic Council of Ministers and carried out by Nordic Ecolabelling with a subgroup of the Nordic Sustainable Consumption and Production group (HKP) as steering group

  • Kazemi, Masoud
    et al.
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Cell and Molecular Biology. Stockholm Univ, Arrhenius Lab, Dept Organ Chem, SE-10691 Stockholm, Sweden .
    Socan, Jaka
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Cell and Molecular Biology, Computational Biology and Bioinformatics.
    Himo, Fahmi
    Stockholm Univ, Arrhenius Lab, Dept Organ Chem, SE-10691 Stockholm, Sweden.
    Åqvist, Johan
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Cell and Molecular Biology, Computational Biology and Bioinformatics.
    Mechanistic alternatives for peptide bond formation on the ribosome2018In: Nucleic Acids Research, ISSN 0305-1048, E-ISSN 1362-4962, Vol. 46, no 11, p. 5345-5354Article in journal (Refereed)
    Abstract [en]

    The peptidyl transfer reaction on the large ribosomal subunit depends on the protonation state of the amine nucleophile and exhibits a large kinetic solvent isotope effect (KSIE similar to 8). In contrast, the related peptidyl-tRNA hydrolysis reaction involved in termination shows a KSIE of similar to 4 and a pH-rate profile indicative of base catalysis. It is, however, unclear why these reactions should proceed with different mechanisms, as the experimental data suggests. One explanation is that two competing mechanisms may be operational in the peptidyl transferase center (PTC). Herein, we explored this possibility by re-examining the previously proposed proton shuttle mechanism and testing the feasibility of general base catalysis also for peptide bond formation. We employed a large cluster model of the active site and different reaction mechanisms were evaluated by density functional theory calculations. In these calculations, the proton shuttle and general base mechanisms both yield activation energies comparable to the experimental values. However, only the proton shuttle mechanism is found to be consistent with the experimentally observed pH-rate profile and the KSIE. This suggests that the PTC promotes the proton shuttle mechanism for peptide bond formation, while prohibiting general base catalysis, although the detailed mechanism by which general base catalysis is excluded remains unclear.

  • Public defence: 2018-10-16 10:00 sal FB54, AlbaNova universitetscentrum, Stockholm
    Rebrov, Oleksii
    Stockholm University, Faculty of Science, Department of Physics.
    Interactions of chiral ions and molecules in gas phase: Towards an understanding of chiral recognition mechanism2018Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    This thesis comprises the research related to interactions of enantiopure amino acids with chiral and achiral molecules in gas phase. The investigation of the mechanism responsible for chiral discrimination is of the special interest in this work. An electrospray ion source platform (Stockholm University), quadrupole time-of-flight mass spectrometer (University of Oslo) and Fourier-transform ion cyclotron resonance mass spectrometer in combination with OPO laser (Centre Laser Infrarouge d'Orsay (CLIO), France)  have been used in our studies. Results of experiments on collisions of enantiopure amino acids, namely phenylalanine (Phe), tryptophan (Trp), and methionine (Met) with chiral and achiral targets in high and low energy regimes are presented. The fragmentation process is discussed in detail and compared with generally accepted models of amino acid fragmentation. Formation of proton bound diastereomeric adducts of amino acid and chiral alcohols (2-butanol and 1-phenylethanol) in single collisions is reported. The emphasis was given to reveal stereochemical effects in above mentioned reactions. The structure and vibrational properties of diastereomeric dimers of tryptophan studied using infrared multiphoton dissociation (IRMPD) spectrometry are presented. Structures and energies of most stable conformers obtained with quantum chemical calculations are described and compared to the experimental data. The stereo-dependent features are underlined and the chiral discrimination using IRMPD is addressed.

  • Elvius, Pehr
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    Dissertatio mechanica de horologiis automatis, cujus partem priorem ex consensu ampliss. facultatis philosophicæ in inclyta regia academia Vpsalensi sub præsidio ... Petri Elvii ... publico bonorum examini modeste submittit Johannes J. Lenander Roslagius in auditorio Gustaviano majori ad d. XX Junii anni MDCCXVII.1717Dissertation (older thesis) (Other academic)
  • Elvius, Pehr
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    De longitudine geographica dissertatio, quam cum consensu & adprobatione amplissimi ordinis philosophici in reg. acad. Vpsaliensi, sub præsidio ... Petri Elvii ... pro gradu, placido bonorum examini, qua par est, modestia sistit s:æ r:æ m:tis alumnus Andreas Duræus O-Gothus, in audit. Gustav. majori d. II. Maji anno MDCCX.1710Dissertation (older thesis) (Other academic)
  • Elvius, Pehr
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    De eclipsibus lunæ disputatio gradualis, quam cum consensu amplissimæ facultatis philosophicæ in academia regia Vpsaliensi præside ... Petro Elvio ... placido bonorum examini submittit s:æ r:æ maj:tis alumnus, Petrus Erichsson O-Gothus. In aud. Gustaviano majori die 3 Aprilis, anno MDCCVII.1707Dissertation (older thesis) (Other academic)
  • Elvius, Pehr
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    Pascha Christianorum cum consensu amplissimi collegii philosophici in regia academia Upsalensi, sub præsidio ... Petri Elvii ... dissertatione graduali publice ventilandum sistit Andreas Hesselius Dalekarlus. In auditorio Gust. majori, die 19. Decemb, anni M DCC V.1705Dissertation (older thesis) (Other academic)
  • Elvius, Pehr
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    De Oelandia dissertatio gradualis, quam, ex adprobatione amplissimi ordinis philosophici, præside ... Petro Elvio ... publicæ bonorum contemplationi modestè submittit Nicolaus O. Vallinus Oelandus, Upsaliæ die 20 Junii anni 1703. Loco horisque consvetis.1703Dissertation (older thesis) (Other academic)
  • Elvius, Pehr
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    Delineatio magnæ fodinæ Cuprimontanæ, quam cum consensu ampliss. facult. philos. in reg. acad. Upsal. sub praesidio ... Petri Elvii ... speciminis academici loco in audit. Gust: majori, d. 19 Decemb. ao. 1702. publice censendam sistit sae. rae mtis. alumnus Olaus Nauclerus Ol. fil. Cuprimontano- Dalekarlus.1702Dissertation (older thesis) (Other academic)
  • Floderus, Johan
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    Dissertatio academica, de varia reipublicae Atheniensis forma, cujus partem posteriorem, cons. ampl. facult. philosoph. reg. acad. Upsal. præside, mag. Johanne Flodero ... publico examini subjicit, stipendiarius Hyltingianus. Johannes Dan. Drissel, Roslagus. In audit. Carol. maj. d. III. Junii, a. MDCCLXXII. Horis, post meridiem, solitis.1772Dissertation (older thesis) (Other academic)
  • Floderus, Johan
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    Dissertatio academica, de varia reipublicae Atheniensis forma, cujus partem priorem. Cons. ampl. facult. philosoph. reg. acad. Upsal. præside, mag. Johanne Flodero ... publico examini subjicit stipendiarius Hultingianus. Johannes Dan. Drissel, Roslagus. In audit. Carol. maj. d. XII. Decembr. a. MDCCLXX. Horis, ante meridiem, solitis.1770Dissertation (older thesis) (Other academic)
  • Floderus, Johan
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    Adagia Theocritea dissertatione academica breviter illustrata. Quam, consensu amplissimi ord. philosoph. in regia academia Upsaliensi, præside mag. Johanne Flodero ... publico examini subjicit, Petrus Hultman, Sudermannus. In audit. Carol. maj. d. V. Decemb. MDCCLXX. H. A. M. S.1770Dissertation (older thesis) (Other academic)
  • Floderus, Johan
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    Disputatio academica de homonymia vocabulorum, dikaios et dikaioun in scriptis N.T. Quam consentiente amplissima facult. philosoph. in regia acad. Upsaliensi, præside mag. Johanne Flodero ... publico examini subjicit in aud. Carol. maj. h. a. m. solitis die XXV Jun. MDCCLXX. Stipendiarius regius Isacus Norberg Angermannus.1770Dissertation (older thesis) (Other academic)
  • Floderus, Johan
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    Disputatio academica sistens observationes philologicas, in II. Petri I. v. 3. Quam, consent. ampliss. facult. phil. in regia academia Upsaliensi, præside mag. Johanne Flodero ... pro gradu publicæ censuræ submittit stipendiarius Nesselianus. Petrus Wäsström, Fierdhundrensis. V. D. M. In audit. Carol. maj. d. XXIX. Maji. MDCCLXX. Horis ante meridiem solitis.1770Dissertation (older thesis) (Other academic)
  • Floderus, Johan
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    Disputatio academica. Ex profanis auctoribus illustratura locutionem scriptorum N.T. aphienai tas [h]amartias quam, consent. ampliss. facult. phil. in regia academia Upsaliensi, præside mag. Johanne Flodero ... pro gradu publicæ censuræ submittit Jonas Sven. Lindblad, V. Goth. ad legion. equest. primar. a sacr. extraord. In audit. Carol. maj. d. IX. Maji. MDCCLXX. Horis ante meridiem solitis.1770Dissertation (older thesis) (Other academic)
  • Floderus, Johan
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    Disputatio explicans r[h]ēsin Paulinam, anthrakas pyros sōreuein epi tēn kephalēn Rom. XII. 20. Quam, consent. ampliss. facult. phil. in regia academia Upsaliensi, præside mag. Johanne Flodero ... pro gradu publice examinandam sistit Petrus Bodin, Vermelandus. V. D. M. In audit. Carol. maj. d. IV. April. MDCCLXX. Horis ante meridiem solitis.1770Dissertation (older thesis) (Other academic)
  • Floderus, Johan
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    Disputatio gradualis sistens observationes philologicas in Apocalypseos XIV. 13. Quam, consent. ampliss. facult. phil. in regia academia Upsaliensi, præside mag. Johanne Flodero ... in audit. Carol. maj. d. XXVIII. Martii MDCCLXX. horis ante merid. solitis. Publice examinandam sistit alumnus Thunianus Jonas Aspelin, Smol. verb. div. min.1770Dissertation (older thesis) (Other academic)
  • Floderus, Johan
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    Disputatio academica de homonymia vocabuli kosmos, in scriptis N.T. Quam, consensu ampl. facult. philosoph. in regia academia Upsaliensi, praeside mag. Johanne Flodero ... pro gradu publice ventilandam sistit stipendiarius regius Laurentius Petri Alenius V. Gothus in audit. Carol. maj. d. XXI. Martii MDCCLXX. Horis ante merid. solitis.1770Dissertation (older thesis) (Other academic)
  • Floderus, Johan
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    Dissertatio gradualis indicans vestigia poëseos Homericæ et Hesiodeæ in oraculis Sibyllinis. Quam, consent. ampliss. facult. philos. in regia academia Upsaliensi, praeside mag. Johanne Flodero ... publice examinandam sistit stipend. Victorinianus Ericus Venerbom V-Gothus. In audit. Carol maj. die XIV. Mart. anni MDCCLXX.1770Dissertation (older thesis) (Other academic)
  • Floderus, Johan
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    Paulus ektrōma 1. Cor. XV. 8. dissertatione academica, illustratus. Quam consent. ampliss. facult. philos. in regia academia Upsaliensi, præside mag. Johanne Flodero ... publico examini subjicit stipendiarius Zedritzianus Petrus Ludovicus Nybler Uplandus in audit. Gustavian. die XXIII. Decemb. anni MDCCLXIX. H. A. M. S.1769Dissertation (older thesis) (Other academic)
  • Floderus, Johan
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    Gymnastica Græcorum ex Pindaro illustrata dissertatione academica cujus partem posteriem consensu ampl. fac. phil. Ups. praeside mag. Johanne Flodero ... pro gradv publice ventilandam sistit Magnus Stagnelius Calmariensis. In audit. Carol. maj. d. XVII Aprilis MDCCLXXIII. H. A. M. S.1773Dissertation (older thesis) (Other academic)
  • Floderus, Johan
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Philosophy.
    Gymnastica Græcorum ex Pindaro illustrata dissertatione academica. Cujus partem priorem consensu ampliss. facult. phil. Ups. præside mag. Johanne Flodero ... publice ventilandam sistit Magnus Stagnelius Calmariensis. In audit. Gustav. die XV. Junii MDCCLXIX. H. A. M. S.1769Dissertation (older thesis) (Other academic)