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  • Ramazanali, Hawar
    Halmstad University, School of Information Technology, Halmstad Embedded and Intelligent Systems Research (EIS), Centre for Research on Embedded Systems (CERES). Saab Training & Simulation, Husqvarna, Sweden.
    Managing Radio and Energy Resources in LTE-Based Military Training Networks2017Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    The number of wireless connected devices are growing exponentially and the importance of this research area is growing as well to meet the known and looming challenges and expectations. The 5:th Generation telecommunications standard is partly embodied by the Machine-to-Machine (M2M) and Internet of Things (IoT) technologies and standards to handle a big part of these devices and connections. An example within the IoT paradigm is military training systems where each system can consist of thousands of battery operated mobile devices and their shifting requirements shall be fullled in an energy-aware manner to increase battery operating times.

    Military training radio networks enables realistic combat training. The services and features provided in commercial telecommunications networks are desirable in these often proprietary and task specic networks, increasing capabilities and functionalities. To facilitate the current and future R&D of LTE based networks for adoption in military training networks and services this doctoral thesis intends to provide the starting ground for the energy-aware LTE based wireless communications. The thesis first presents general solutions on how to meet traffic deadlines in wireless networks for large number of nodes, and then continues with solutions for energy-aware LTE-based communications for the User Equipments (UEs).

    The work builds on the problem formulation how to provide energy-aware resource handling for LTE-based military training networks from where three research questions are derived. From the research questions we derive different hypotheses and then test these within the investigated area to answer the research questions.

    The contributions of this work are within areas of resource handling and power saving for mobile devices. In the first area an admission control using deterministic analysis is proposed fullling traffic requirements for military training mobile nodes. This admission control is enhanced for multiple-channel base stations, and evaluated using mobile nodes with different heterogeneous traffic requirements. In the second part energy-awareness is in focus for LTE/LTE-A based networks. The main power saving method for LTE/LTE-A UEs, Discontinuous Reception (DRX) mechanism, is evaluated and models for DRX in Idle and Connected state are proposed including metrics for wake-up delay and power saving. Additionally a mean queuing delay analysis is proposed for a variant of the Connected state DRX. Using these models and metrics, practical design guidelines for tuning of DRX parameters are proposed, including optimization of DRX parameters for either minimizing delay or maximizing power saving.

  • Donoso, Alejandra
    Stockholm University.
    Expresiones de movimiento en español como segunda lengua y como lengua heredada: Conceptualización y entrega del Camino, la Manera y la Base2016Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    The current thesis is based on four individual studies which aim to account for the expression of motion events (ME) in Spanish and Swedish as first languages (L1), in Swedish as a second language (L2), and in Spanish as a heritage language (SHL). The data, resulting from audio-recordings of different sorts of stimuli, have been analyzed with special focus on (1) the most common structures used for referring to various types of ME, (2) the types and amount of information provided by the participants, in particular as regards the semantic components Path, Manner and Ground, and (3) grammatical aspect and types of syntactic structures resorted to, including the correlation between the two latter factors and speakers’ discursive preferences.

         Study 1 sets out to explore how Spanish and Swedish native speakers convey information about motion. The results show that the Swedish L1 speakers produced a wider range of descriptions concerning Manner and Path than the Spanish L1 speakers; furthermore, both groups delivered detailed Ground descriptions, although the Swedish native speakers expressed final destinations (endpoints) of ME to a greater extent.

         Study 2 aims to investigate to what extent Swedish L1 patterns for motion encoding are still at play in the acquisition of Spanish L2 even at advanced stages of L2 acquisition. The results show that the learner group used a larger amount of Path particles and Ground adjuncts (in particular those referring to endpoints) than did the Spanish natives; this finding supports the claim that L2 learners rely on the lexicalization patterns of their L1 when describing ME in an L2. As for Manner, the L2 speakers were found to express this component mainly outside the verb, and to deliver more information about Manner than the Spanish natives.

         Study 3 addresses the construal of ME in Swedish speakers of L2 Spanish, in particular concerning the encoding of motion endpoints and Manner of motion. The results show that the Swedish learners of Spanish exhibited the same, high frequencies of endpoint marking as did their monolingual Swedish peers, thus deviating from the Spanish native pattern. Moreover, the L2 speakers used the same amount of Manner verbs as did the Spanish natives but tended consistently to provide additional Manner information in periphrastic constructions.

         Finally, Study 4 sets out to analyze the ways in which L1 Spanish/L2 Swedish early and late bilinguals express ME in SHL. The aim is to show in which ways and to what extent the typological patterns for motion encoding in the L2 may impact on motion encoding in the L1 with regard to three parameters: (1) age of onset (AO) of the acquisition of L2, (2) length of residence (LoR) in the L2 environment and (3) contact level with the L1 (CL). The focus data, consisting of oral re-tellings produced by the bilinguals, were compared to analogous data produced by two control groups (native speakers of Spanish and Swedish) in order to analyze conflation patterns regarding Manner, Path and Ground information. The analysis points to the conclusion that both the individuals’ AO of L2 acquisition and their LoR in the L2 environment have affected their L1 conceptualization patterns while their CL plays a subordinate role.

         In summary, the findings lend support to the idea that the habitual conceptualization of events in the L1 influences L2 acquisition; conversely, the conceptual patterns of the L2 have an impact on L1 usage in bilinguals, especially in combination with an early AO and a long LoR.

  • Dini, Hoda
    Jönköping University, School of Engineering, JTH, Materials and Manufacturing. Jönköping University, School of Engineering, JTH. Research area Materials and manufacturing – Casting.
    As-cast AZ91D magnesium alloy properties: Effects of microstructure and temperature2017Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    Today, there is an essential need for lightweight, energy-efficient, environmentally benign engineering systems, and this is the driving force behind the development of a wide range of structural and functional materials for energy generation, energy storage, propulsion, and transportation. These challenges have motivated the use of magnesium alloys for lightweight structural systems. Magnesium has a density of 1.74 g/cm3, which is almost 30% less than that of aluminium, one quarter of steel, and almost identicalto polymers. The ease of recycling magnesium alloys as compared to polymers makes them environmentally attractive, but their poor mechanical performance is the primary reason for the limited adoption of these alloys for structural applications.

    The Mg-Al-Zn alloy AZ91D exhibits an excellent combination of strength, die-castability, and corrosion resistance. However, its mechanical performance with regard to creep strength, for example, at evaluated temperatures is poor. Moreover, very little is known about the correlation between its mechanical properties and microstructural features. This thesis aims to provide new knowledge regarding the role played by microstructure in the mechanical performance of the magnesium alloy. The properties/performance of the material in relation to process parameters became of great interest during the investigation.

    An exhaustive characterisation of the grain size, secondary dendrite arm spacing (SDAS) distribution, and fraction of Mg17Al12 was performed using optical and electron backscatter diffraction (EBSD). These microstructural parameters were correlated to the offset yield point (Rp0.2), fracture strength, and elongation to failure of the material. It was proposed that the intermetallic phase, Mg17Al12, plays an important role in determining the mechanical and physical properties of the alloy in a temperature range of room temperature to 190°C by forming a rigid network of intermetallic. The presence of this network was confirmed by studying the thermal expansion behaviour of samples of the alloy containing different amounts of Mg17Al12.

    A physically based constitutive model with a wide validity range was successfully adapted to describe the flow stress behaviour of AZ91D with various microstructures. The temperature-dependent variables of the model correlated quite well with the underlying physics of the material. The model was validated through comparison with dislocation densities obtained using EBSD.

    The influence of high-pressure die-cast parameters on the distortion and residual stress of the cast components was studied, as were distortion and residual stress in components after shot peening and painting. Interestingly, it was found that intensification pressure has a major effect on distortion and residual stresses, and that the temperature of the fixed half of the die had a slight influence on the component's distortion and residual stress.

  • Einarsson, Anna
    Royal College of Music in Stockholm, Department of Composition and Conducting.
    Singing the body electric: Understanding the role of embodiment in performing and composing interactive music2017Doctoral thesis, monograph (Other academic)
    Abstract [en]

    Almost since the birth of electronic music, composers have been fascinated by the prospect of integrating the human voice with its expressiveness and complexity into electronic musical works. This thesis addresses how performing with responsive technologies in mixed works, i.e. works that combine an acoustic sound source with a digital one, is experienced by participating singers, adopting an approach of seamlessness, of zero – or invisible – interface, between singer and computer technology. It demonstrates how the practice of composing and the practice of singing both are embodied activities, where the many-layered situation in all its complexity is of great importance for a deepened understanding. The overall perspective put forward in this thesis is that of music as a sounding body to resonate with, where the resonance, a process of embodying, of feeling and emotion, guides the decision-making. The core of the investigation is the lived experiences through the process of composing and performing three musical works. One result emerging from this process is the suggested method of calibration, according to which a bodily rooted attention forms a kind of joint attention towards the work in the making. Experiences from these three musical works arrive in the formulation of an over-arching framework entailing a view of musical composition as a process of construction – and embodied mental simulation – of situations, whose dynamics unfold to engage musicians and audience through shifting fields of affordances, based on a shared landscape of affordances.

  • Melén Fäldt, Maria
    Kristianstad University, Learning Resource Centre.
    Högskolepedagogisk debatt: pedagogiska utvecklingsprojekt med studentens lärande i centrum2017Collection (editor) (Other (popular science, discussion, etc.))
  • Orre, Inger
    KTH, Superseded Departments (pre-2005), Industrial Economics and Management.
    Reporterskap: äventyr, irrbloss, dygder2001Doctoral thesis, monograph (Other academic)
  • Eriksson, Lars
    et al.
    Örebro universitet, Restaurang- och hotellhögskolan.
    Öström, Åsa
    Örebro universitet, Restaurang- och hotellhögskolan.
    Akner-Koler, Cheryl
    Örebro universitet, Restaurang- och hotellhögskolan.
    Embodied aesthetic movements during mealtime: a provocative method for design innovation of culinary utensils2011Conference paper (Other academic)
    Abstract [en]

    In 2010, the project MER was funded be The Knowledge (KK) foundation. Lars Eriksson, associate professor in applied aestetics and creative events at Grythytte Academy Örebro University, initiated the project MER which focuses on the way people move and interact in the environment around the meal.

    This project has conducted a number of studies about the meeting between utensils, food and the guest in motion, creating the culinary experience. The poster presents a summary of a provocative method applied in all of the different studies.

  • Melén Fäldt, Maria
    Kristianstad University, School of Health and Society. Kristianstad University, Learning Resource Centre.
    Högskolepedagogisk debatt: Tema: Pedagogiska utvecklingsprojekt med studentens lärande i centrum2017Collection (editor) (Other academic)
  • Ringarp, Johanna
    et al.
    Södertörn University, School of Historical and Contemporary Studies, Institute of Contemporary History.
    Forsell, Håkan
    Levande campus: Utmaningar och möjligheter för Södertörns högskola i den nya regionala stadskärnan i Flemingsberg2017Collection (editor) (Other academic)
    Abstract [sv]

    Den 21 september 2016 anordnade Samtidshistoriska institutet som en del av Södertörns högskolas 20-års jubileum vittnesseminariet ”Levande campus. Utmaningar och möjligheter för Södertörns högskola i den nya regionala stadskärnan i Flemingsberg”.

    Utgångspunkten för seminariet var att under jubileumsåret inte bara blicka bakåt, utan också lufta idéer kring högskolans framtida utmaningar och utvecklingsmöjligheter. Frågor som diskuterades handlade om hur det sociala landskapet bör gestaltas när det är en kunskapsinstitution som utgör navet för platsen, samt vilken roll Södertörns högskola ska ha i den nya regionala stadskärnan som håller på att växa fram.

  • Sundström, Gerdt
    Jönköping University, School of Health and Welfare, HHJ, Institute of Gerontology. Jönköping University, School of Health and Welfare, HHJ. SALVE (Social challenges, Actors, Living conditions, reseach VEnue). Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping).
    Jag går mot döden vart jag går2017In: Äldre i centrum, ISSN 1653-3585, no 4, 87-89 p.Article in journal (Other (popular science, discussion, etc.))
    Abstract [sv]

    "Det finns många föreställningar om döden, minst lika många om döendet. Den irländske läkaren Seamus O'Mahony är kritisk till nutidens syn på sjukdom och död, skriver Gerdt Sundström."

  • Jonason, Patricia
    et al.
    Södertörn University, School of Social Sciences, Public Law.
    Rosengren, Anna
    The Right of Access to Information and the Right to Privacy: A Democratic Balancing Act2017Collection (editor) (Other academic)
    Abstract [en]

    This publication gathers presentations from an international and trans-disciplinary workshop held at Södertörn University in December 2016.

    The workshop entitled The Right of Access to Information and the Right to Privacy: A Democratic Balancing Act was one of the many events which celebrated the 250th anniversary of the Swedish Freedom of the Press Act, the first legal instrument in the world laying down the right of access to official documents. A starting point for the workshop was the assumption that the right of access to information and the right to privacy are both necessary pre-conditions for a democratic society. Researchers from a broad range of fields were invited to discuss how these assumptions should be examined, and how the balance between the two interests should be assessed when conflicting with each other. The objective of the workshop was to broaden our understanding of various national and disciplinary approaches to the democratic balance between the right of access and the right to privacy.

    Among the conclusions we may draw from the workshop, and the articles emanating from it, is the confirmation of the need to strike the balance between the right of access and the right to privacy. This is certainly difficult, but since the two interests are both of such importance for democracy, we constantly need to make the effort. The articles in this volume contain information on some of the areas that need our further attention.

  • Demand side flexibility in the Nordic electricity market: From a Distribution System Operator Perspective2017Book (Other academic)
    Abstract [en]

    The organisation for the Nordic energy regulators, NordREG, has ordered this study to explore status of demand side flexibility among Nordic distribution system operators (DSOs). Demand side response is a question of mobilising potential flexibility in how and when end users choose to use energy, and how such flexibility can provide value to the network. Network value can be reduced or deferred investments, better system reliability or other system cost reductions. This report addresses concepts for utilising demand response and related regulatory issues. The report also includes an interview study among selected DSOs in the Nordic countries. This addresses current status, how flexibility can be a value for their business, what they see as barriers and planned activities relating to demand response.

  • Nakamura, Rumi
    et al.
    Austrian Acad Sci, Space Res Inst, Graz, Austria..
    Nagai, Tsugunobu
    Tokyo Inst Technol, Tokyo, Japan..
    Birn, Joachim
    Space Sci Inst, Boulder, CO USA..
    Sergeev, Victor A.
    St Petersburg State Univ, St Petersburg, Russia..
    Le Contel, Olivier
    UPMC Univ Paris 06, Univ Paris Sud, CNRS, Lab Phys Plasmas,Ecole Polytech,Observ Paris, Paris, France..
    Varsani, Ali
    Austrian Acad Sci, Space Res Inst, Graz, Austria..
    Baumjohann, Wolfgang
    Austrian Acad Sci, Space Res Inst, Graz, Austria..
    Nakamura, Takuma
    Austrian Acad Sci, Space Res Inst, Graz, Austria..
    Apatenkov, Sergey
    St Petersburg State Univ, St Petersburg, Russia..
    Artemyev, Anton
    Univ Calif Los Angeles, Los Angeles, CA USA..
    Ergun, Robert E.
    Univ Colorado, LASP, Boulder, CO 80309 USA..
    Fuselier, Stephen A.
    Southwest Res Inst, San Antonio, TX USA..
    Gershman, Daniel J.
    NASA, GSFC, Greenbelt, MD USA..
    Giles, Barbara J.
    NASA, GSFC, Greenbelt, MD USA..
    Khotyaintsev, Yuri V.
    Uppsala University, Disciplinary Domain of Science and Technology, Physics, Swedish Institute of Space Physics, Uppsala Division.
    Lindqvist, Per-Arne
    Royal Inst Technol, Stockholm, Sweden..
    Magnes, Werner
    Austrian Acad Sci, Space Res Inst, Graz, Austria..
    Mauk, Barry
    Johns Hopkins Univ, Appl Phys Lab, Laurel, MD USA..
    Russell, Christopher T.
    Univ Calif Los Angeles, Los Angeles, CA USA..
    Singer, Howard J.
    NOAA, Space Weather Predict Ctr, Boulder, CO USA..
    Stawarz, Julia
    Imperial Coll London, Dept Phys, London, England..
    Strangeway, Robert J.
    Univ Calif Los Angeles, Los Angeles, CA USA..
    Anderson, Brian
    Johns Hopkins Univ, Appl Phys Lab, Laurel, MD USA..
    Bromund, Ken R.
    NASA, GSFC, Greenbelt, MD USA..
    Fischer, David
    Austrian Acad Sci, Space Res Inst, Graz, Austria..
    Kepko, Laurence
    NASA, GSFC, Greenbelt, MD USA..
    Le, Guan
    NASA, GSFC, Greenbelt, MD USA..
    Plaschke, Ferdinand
    Austrian Acad Sci, Space Res Inst, Graz, Austria..
    Slavin, James A.
    Univ Michigan, Dept Climate & Space Sci & Engn, Ann Arbor, MI USA..
    Cohen, Ian
    Johns Hopkins Univ, Appl Phys Lab, Laurel, MD USA..
    Jaynes, Allison
    Univ Colorado, LASP, Boulder, CO 80309 USA..
    Turner, Drew L.
    Aerosp Corp, Space Sci Dept, POB 92957, Los Angeles, CA 90009 USA..
    Near-Earth plasma sheet boundary dynamics during substorm dipolarization2017In: Earth Planets and Space, ISSN 1343-8832, E-ISSN 1880-5981, Vol. 69, 129Article in journal (Refereed)
    Abstract [en]

    We report on the large-scale evolution of dipolarization in the near-Earth plasma sheet during an intense (AL similar to -1000 nT) substorm on August 10, 2016, when multiple spacecraft at radial distances between 4 and 15 RE were present in the night-side magnetosphere. This global dipolarization consisted of multiple short-timescale (a couple of minutes) Bz disturbances detected by spacecraft distributed over 9 MLT, consistent with the large-scale substorm current wedge observed by ground-based magnetometers. The four spacecraft of the Magnetospheric Multiscale were located in the southern hemisphere plasma sheet and observed fast flow disturbances associated with this dipolarization. The high-time-resolution measurements from MMS enable us to detect the rapid motion of the field structures and flow disturbances separately. A distinct pattern of the flow and field disturbance near the plasma boundaries was found. We suggest that a vortex motion created around the localized flows resulted in another fieldaligned current system at the off-equatorial side of the BBF-associated R1/R2 systems, as was predicted by the MHD simulation of a localized reconnection jet. The observations by GOES and Geotail, which were located in the opposite hemisphere and local time, support this view. We demonstrate that the processes of both Earthward flow braking and of accumulated magnetic flux evolving tailward also control the dynamics in the boundary region of the near-Earth plasma sheet.

  • Nordic data hubs in electricity system: Differences and similarities2017Book (Other academic)
    Abstract [en]

    The Nordic ministries and regulators aim to harmonise the electricity retail markets to reduce market entry barriers for retailers from the other Nordic countries, hence promoting competition and customer choice and reduced costs of operating in different national markets. The Electricity Market Group under the Nordic Council off Ministers gave THEMA Consulting Group the task of analysing how the datahub projects can support the harmonisation process. This study explores the design and functionalities of existing and planned data hubs and how data hubs can contribute towards more harmonised end-user markets. Two main recommendations are made; enabling interoperability between hubs, and establishing an advisory group to identify regulatory and technical barriers to harmonisation and propose measures.

  • Zachrisson, Torun
    Stockholm University, Faculty of Humanities, Department of Archaeology and Classical Studies, Archaeology.
    Tamkatten: en nykomling under tidig järnålder2017In: Fauna och flora : populär tidskrift för biologi, ISSN 0014-8903, Vol. 111, no 2, 32-34 p.Article in journal (Other (popular science, discussion, etc.))
  • Karlsson, Torbjörn
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Haematology.
    Evaluation of a competitive hepcidin ELISA assay in the differential diagnosis of iron deficiency anaemia with concurrent inflammation and anaemia of inflammation in elderly patients2017In: Journal of Inflammation, ISSN 1476-9255, E-ISSN 1476-9255, Vol. 14, 21Article in journal (Refereed)
    Abstract [en]

    In this study, a competitive hepcidin ELISA assay was evaluated for its ability to differentiate between iron deficiency anaemia with concurrent inflammation and anaemia of inflammation in elderly patients, using the absence of stainable bone marrow iron as the diagnostic criterion for iron deficiency. In addition, correlation coefficients for hepcidin versus C-reactive protein, ferritin and interleukin-6 were determined. The optimal cut-off for hepcidin was 21 mu g/L, corresponding to sensitivity and specificity of 100% and 67%, respectively, for iron deficiency. For ferritin, a sensitivity and specificity of 91% and 83%, respectively, correspond to an optimal cut-off of 87 mu g/L. Receiver operating characteristics curve analysis revealed that ELISA analysis of hepcidin is not superior to ferritin in the diagnosis of iron deficiency in elderly anaemic patients with concurrent inflammation. Hepcidin shows a strong positive correlation with ferritin, and also correlates positively with C-reactive protein in this patient population.

  • Olofsson, Tommy
    Linnaeus University, Faculty of Arts and Humanities, Department of Film and Literature.
    God årgång2017In: Axess, ISSN 1651-0941, no 9, 125-127 p.Article, book review (Other academic)
    Abstract [sv]

    Recension av Bill Goldsteins The World Broke in Two: Virginia Woolf, T.S. Eliot, D.H. Lawrence, E.M. Forster, and the Year that Changed Literature (Henry Holt & Co, 2017). Det år som denna studie kretsar kring är 1922, året då Ulysses publicerades och enligt Goldstein medförde ett slags estetiskt paradigmskifte inom berättarkonsten.

  • Vaithilingam, Vijayaganapathy
    et al.
    CSIRO, Mat Sci & Engn, N Ryde, NSW, Australia..
    Steinkjer, Bjorg
    Norwegian Univ Sci & Technol NTNU, Ctr Mol Inflammat Res, Trondheim, Norway.;Norwegian Univ Sci & Technol NTNU, Dept Canc Res & Mol Med, Trondheim, Norway..
    Ryan, Liv
    Norwegian Univ Sci & Technol NTNU, Ctr Mol Inflammat Res, Trondheim, Norway.;Norwegian Univ Sci & Technol NTNU, Dept Canc Res & Mol Med, Trondheim, Norway..
    Larsson, Rolf
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Immunology, Genetics and Pathology. Corline Syst AB, Uppsala, Sweden.
    Tuch, Bernard Edward
    CSIRO, Mat Sci & Engn, N Ryde, NSW, Australia.;Univ Sydney, Sch Med Sci, Sydney, NSW, Australia..
    Oberholzer, Jose
    Univ Illinois, Dept Surg, Chicago, IL 60680 USA..
    Rokstad, Anne Mari
    Norwegian Univ Sci & Technol NTNU, Ctr Mol Inflammat Res, Trondheim, Norway.;Norwegian Univ Sci & Technol NTNU, Dept Canc Res & Mol Med, Trondheim, Norway.;Cent Norway Reg Hlth Author RHA, Trondheim, Norway..
    In Vitro and In Vivo Biocompatibility Evaluation of Polyallylamine and Macromolecular Heparin Conjugates Modified Alginate Microbeads2017In: Scientific Reports, ISSN 2045-2322, E-ISSN 2045-2322, Vol. 7, 11695Article in journal (Refereed)
    Abstract [en]

    Host reactivity to biocompatible immunoisolation devices is a major challenge for cellular therapies, and a human screening model would be of great value. We designed new types of surface modified barium alginate microspheres, and evaluated their inflammatory properties using human whole blood, and the intraperitoneal response after three weeks in Wistar rats. Microspheres were modified using proprietary polyallylamine (PAV) and coupled with macromolecular heparin conjugates (Corline Heparin Conjugate, CHC). The PAV-CHC strategy resulted in uniform and stable coatings with increased anticlot activity and low cytotoxicity. In human whole blood, PAV coating at high dose (100 mu g/ml) induced elevated complement, leukocyte CD11b and inflammatory mediators, and in Wistar rats increased fibrotic overgrowth. Coating of high dose PAV with CHC significantly reduced these responses. Low dose PAV (10 mu g/ml) +/- CHC and unmodified alginate microbeads showed low responses. That the human whole blood inflammatory reactions paralleled the host response shows a link between inflammatory potential and initial fibrotic response. CHC possessed anti-inflammatory activity, but failed to improve overall biocompatibility. We conclude that the human whole blood assay is an efficient first-phase screening model for inflammation, and a guiding tool in development of new generation microspheres for cell encapsulation therapy.

  • Bellucci, Jeremy
    et al.
    Swedish Museum of Natural History, Department of Geology.
    Joshua, Snape
    Swedish Museum of Natural History, Department of Geology.
    Whitehouse, Martin
    Swedish Museum of Natural History, Department of Geology.
    Nemchin, Alexander
    Direct Pb Isotopic Analysis of a Nuclear Fallout Debris Particle from the Trinity Nuclear Test2017In: Analytical Chemistry, ISSN 0003-2700, E-ISSN 1520-6882, Vol. 89, 1887-1891 p.Article in journal (Refereed)
    Abstract [en]

    The Pb isotope composition of a nuclear fallout debris particle has been directly measured in post-detonation materials produced during the Trinity nuclear test by a secondary ion mass spectrometry (SIMS) scanning ion image technique (SII). This technique permits the visual assessment of the spatial distribution of Pb and can be used to obtain full Pb isotope compositions in user-defined regions in a 70 μm × 70 μm analytical window. In conjunction with backscattered electron (BSE) and energy-dispersive spectroscopy (EDS) mapping of the same particle, the Pb measured in this fallout particle cannot be from a major phase in the precursor arkosic sand. Similarly, the Pb isotope composition of the particle is resolvable from the surrounding glass at the 2σ uncertainty level (where σ represents the standard deviation). The Pb isotope composition measured in the particle here is in excellent agreement with that inferred from measurements of green and red trinitite, suggesting that these types of particles are responsible for the Pb isotope compositions measured in both trinitite glasses. 

  • Lodin, Karin
    et al.
    Karolinska Inst, Div Family Med & Primary Care, Dept Neurobiol Care Sci & Soc, Huddinge, Sweden.;Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden..
    Lekander, Mats
    Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden.;Stockholm Univ, Stress Res Inst, Stockholm, Sweden..
    Syk, Jörgen
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health. Karolinska Inst, Div Family Med & Primary Care, Dept Neurobiol Care Sci & Soc, Huddinge, Sweden.;Karolinska Inst, Ctr Allergy Res, Stockholm, Sweden.; Stockholm Cty Council, Acad Primary Hlth Care Ctr, Stockholm, Sweden..
    Alving, Kjell
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health.
    Petrovic, Predrag
    Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden..
    Andreasson, Anna
    Karolinska Inst, Div Family Med & Primary Care, Dept Neurobiol Care Sci & Soc, Huddinge, Sweden.;Stockholm Univ, Stress Res Inst, Stockholm, Sweden.;Macquarie Univ, Dept Psychol, N Ryde, NSW, Australia..
    Longitudinal co-variations between inflammatory cytokines, lung function and patient reported outcomes in patients with asthma2017In: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 12, no 9, e0185019Article in journal (Refereed)
    Abstract [en]

    Background Asthma is a chronic inflammatory respiratory disorder associated with reduced lung function and poor quality of life. The condition is also associated with poor self-rated health, a major predictor of objective health trajectories. Of biological correlates to self-rated health, evidence suggests a role for inflammatory cytokines and related sickness behaviours. However, this is mainly based on cross-sectional data, and the relation has not been investigated in patients with chronic inflammatory conditions. Objective To investigate inflammatory cytokines, lung function, sickness behaviour and asthma-related quality of life as determinants of self-rated health in patients with asthma, and to investigate if these variables co-vary over time. Methods Plasma cytokines (IL-5, IL-6), lung function (FEV1), sickness behaviour, asthma-related quality of life and self-rated health were assessed in 181 patients with allergic asthma aged 18-64 years in a one-year longitudinal study. Mixed effect regression models and Spearman's correlation were performed to analyse the associations between repeated measurements. Results More sickness behaviour and poorer asthma-related quality of life were associated with poorer self-rated health (p's<0.001). In men, both low and high levels of interleukin (IL)-6 and poorer lung function were related with poorer self-rated health (p's<0.05). Over the year, improved asthma-related quality of life was associated with better self-rated health (Spearman's rho = -0.34 women,-0.36 men, p's<0.01). Further, if sickness behaviour decreased, self-rated health improved, but only in women (Rho = -0.21, p<0.05). Increased FEV1 in men was associated with an increase in IL-6 (Rho = 0.24, p<0.05) as well as improved self-rated health (Rho = -0.21, p<0.05) and asthma-related quality of life (Rho = 0.29, p<0.01) over the year. Conclusion The study highlights the importance of subjectively perceived sickness behaviour and asthma-related quality of life together with lung function as determinants of self-rated health in asthmatic patients. The importance of inflammatory activation for patient reported outcomes in chronic inflammatory conditions need further investigation.

  • Bellucci, Jeremy
    et al.
    Swedish Museum of Natural History, Department of Geology.
    Whitehouse, Martin
    Swedish Museum of Natural History, Department of Geology.
    Snape, Joshua
    Swedish Museum of Natural History, Department of Geology.
    Halogen and Cl isotopic systematics in Martian phosphates: Implications for the Cl cycle and surface halogen reservoirs on Mars2017In: Earth and Planetary Science Letters, ISSN 0012-821X, E-ISSN 1385-013X, Vol. 458, 192-202 p.Article in journal (Refereed)
    Abstract [en]

    The Cl isotopic compositions and halogen (Cl, F, Br, and I) abundances in phosphates from eight Martian meteorites, spanning most rock types and ages currently available, have been measured in situ by Secondary Ion Mass Spectrometry (SIMS). Likewise, the distribution of halogens has been documented by x-ray mapping. Halogen concentrations range over several orders of magnitude up to some of the largest concentrations yet measured in Martian samples or on the Martian surface, and the inter-element ratios are highly variable. Similarly, Cl isotope compositions exhibit a larger range than all pristine terrestrial igneous rocks. Phosphates in ancient (>4 Ga) meteorites (orthopyroxenite ALH 84001 and breccia NWA 7533) have positive d37Cl anomalies (+1.1 to +2.5 ‰).  These samples also exhibit explicit whole rock and grain scale evidence for hydrothermal or aqueous activity. In contrast, the phosphates in the younger basaltic Shergottite meteorites (<600 Ma) have negative d37Cl anomalies (-0.2 to -5.6 ‰).  Phosphates with the largest negative d37Cl anomalies display zonation where the rims of the grains are enriched in all halogens and have significantly more negative d37Cl anomalies indicating interaction with the surface of Mars during the latest stages of basalt crystallization. The phosphates with no textural, major element, or halogen enrichment evidence for mixing with this surface reservoir have an average d37Cl of -0.6 ‰, which suggests a similar Cl isotope composition between Mars, the Earth, and the Moon. The only process known to fractionate Cl isotopes, both positively and negatively, is formation of perchlorate, which has been detected in weight percent concentrations on the Martian surface. The age range and obvious mixing history of the phosphates studied here suggest perchlorate formation and halogen cycling via brines, which have also been observed on the Martian surface, has been active throughout Martian history. 

  • Stengel, Martin
    et al.
    Stapelberg, Stefan
    Sus, Oliver
    Schlundt, Cornelia
    Poulsen, Caroline
    Thomas, Gareth
    Christensen, Matthew
    Henken, Cintia Carbajal
    Preusker, Rene
    Fischer, Juergen
    Devasthale, Abhay
    SMHI, Research Department, Atmospheric remote sensing.
    Willén, Ulrika
    SMHI, Research Department, Climate research - Rossby Centre.
    Karlsson, Karl-Göran
    SMHI, Research Department, Atmospheric remote sensing.
    McGarragh, Gregory R.
    Proud, Simon
    Povey, Adam C.
    Grainger, Roy G.
    Meirink, Jan Fokke
    Feofilov, Artem
    Bennartz, Ralf
    Bojanowski, Jedrzej S.
    Hollmann, Rainer
    Cloud property datasets retrieved from AVHRR, MODIS, AATSR and MERIS in the framework of the Cloud_cci project2017In: Earth System Science Data, ISSN 1866-3508, E-ISSN 1866-3516, Vol. 9, no 2, 881-904 p.Article in journal (Refereed)
  • Lindskog, Magnus
    et al.
    SMHI, Research Department, Meteorology.
    Ridal, Martin
    SMHI, Research Department, Meteorology.
    Thorsteinsson, Sigurdur
    Icelandic Meteorological Office, Reykjavík, Iceland.
    Ning, Tong
    Lantmäteriet.
    Data assimilation of GNSS zenith total delays from a Nordic processing centre2017In: Atmospheric Chemistry And Physics, ISSN 1680-7316, E-ISSN 1680-7324, Vol. 17, no 22, 13983-13998 p.Article in journal (Refereed)
  • Andersson, Camilla
    et al.
    SMHI, Research Department, Air quality.
    Alpfjord, Helene
    SMHI, Professional Services.
    Robertson, Lennart
    SMHI, Research Department, Air quality.
    Karlsson, Per Erik
    Miljöforskningsinstitutet.
    Engardt, Magnuz
    SMHI, Research Department, Air quality.
    Reanalysis of and attribution to near-surface ozone concentrations in Sweden during 1990-20132017In: Atmospheric Chemistry And Physics, ISSN 1680-7316, E-ISSN 1680-7324, Vol. 17, no 22Article in journal (Refereed)
  • Rehnberg, Hanna Sofia
    Södertörn University, School of Culture and Education, Swedish Language. Södertörn University, School of Social Sciences, Academy of Public Administration.
    På väg: Berättelser om Trafikverket2017Report (Other academic)
    Abstract [sv]

    Många har saker att säga om Trafikverket, men vad säger trafikverkarna själva? I denna rapport kommer myndighetens chefer och medarbetare till tals.

    De berättar om stolthet, kompetens och engagemang, men också om en brist på helhetssyn och om upplevelsen av att det inte är tillräckligt högt i tak i organisationen. De resonerar om den balansgång som följer av att vara en myndighet och att samtidigt likna ett företag, och om dragkampen mellan det ”det hårda” och ”det mjuka”.

    Genom en väv av röster, sammanställda och tolkade med hjälp av narratologi och teori om organisationskultur, skapas en övergripande berättelse om Trafikverket i ett tidigt skede i den unga myndighetens historia.

  • Pfankuchen, Daniel Bastian
    et al.
    Rheinische Friedrich Wilhelms Univ Bonn, Pharmaceut Inst, Bonn, Germany..
    Baltes, Fabian
    Rheinische Friedrich Wilhelms Univ Bonn, Pharmaceut Inst, Bonn, Germany..
    Batool, Tahira
    Uppsala University, Science for Life Laboratory, SciLifeLab. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology.
    Li, Jin-Ping
    Uppsala University, Science for Life Laboratory, SciLifeLab. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology.
    Schlesinger, Martin
    Rheinische Friedrich Wilhelms Univ Bonn, Pharmaceut Inst, Bonn, Germany..
    Bendas, Gerd
    Rheinische Friedrich Wilhelms Univ Bonn, Pharmaceut Inst, Bonn, Germany..
    Heparin antagonizes cisplatin resistance of A2780 ovarian cancer cells by affecting the Wnt signaling pathway2017In: OncoTarget, ISSN 1949-2553, E-ISSN 1949-2553, Vol. 8, no 40, 67553-67566 p.Article in journal (Refereed)
    Abstract [en]

    Low molecular weight heparin (LMWH), the guideline based drug for prophylaxis and treatment of cancer-associated thrombosis, was recently shown to sensitize cisplatin resistant A2780cis human ovarian cancer cells for cisplatin cytotoxicity upon 24 h pretreatment with 50 mu g x mL(-1) of the LMWH tinzaparin in vitro, equivalent to a therapeutic dosage. Thereby, LMWH induced sensitization by transcriptional reprogramming of A2780cis cells via not yet elucidated mechanisms that depend on cellular proteoglycans. Here we aim to illuminate the underlying molecular mechanisms of LMWH in sensitizing A2780cis cells for cisplatin. Using TCF/LEF luciferase promotor assay (Top/Flash) we show that resistant A2780cis cells possess a threefold higher Wnt signaling activity compared to A2780 cells. Furthermore, Wnt pathway blockade by FH535 leads to higher cisplatin sensitivity of A2780cis cells. Glypican-3 (GPC3) is upregulated in A2780cis cells in response to LMWH treatment, probably as counter-regulation to sustain the high Wnt activity against LMWH. Hence, LMWH reduces the cisplatin-induced rise in Wnt activity and TCF-4 expression in A2780cis cells, but keeps sensitive A2780 cells unaffected. Consequently, Wnt signaling pathway appears as primary target of LMWH in sensitizing A2780cis cells for cisplatin toxicity. Considering the outstanding role of LMWH in clinical oncology, this finding appears as promising therapeutic option to hamper chemoresistance.

  • Johansson, Frank
    et al.
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics, Animal ecology.
    Halvarsson, Peter
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics, Animal ecology.
    Mikolajewski, Dirk J.
    Free Univ Berlin, Inst Biol, Berlin, Germany..
    Höglund, Jacob
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics, Animal ecology.
    Phylogeography and larval spine length of the dragonfly Leucorhinia dubia in Europe2017In: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 12, no 9, e0184596Article in journal (Refereed)
    Abstract [en]

    Presence or absence of predators selects for different kind of morphologies. Hence, we expect variation in traits that protect against predators to vary over geographical areas where predators vary in past and present abundance. Abdominal larval spines in dragonfly larvae provide protection against fish predators. We studied geographical variation in larval spine length of the dragonfly Leucorrhinia dubia across Western Europe using a phylogenetic approach. Larvae were raised in a common garden laboratory experiment in the absence of fish predators. Results show that larvae from northern Europe (Sweden and Finland) had significantly longer larval spines compared to larvae from western and central Europe. A phylogeny based on SNP data suggests that short larval spines is the ancestral stage in the localities sampled in this study, and that long spines have evolved in the Fenno-Scandian clade. The role of predators in shaping the morphological differences among the sampled localities is discussed.

  • Ghoshal, Arunangshu
    et al.
    Kings Coll London, Div Canc Studies Translat Oncol & Urol Res, London SE1 9RT, England.;Tata Mem Hosp, Dept Palliat Med, Bombay 400012, Maharashtra, India..
    Garmo, Hans
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences. Kings Coll London, Div Canc Studies Translat Oncol & Urol Res, London SE1 9RT, England.
    Arthur, Rhonda
    Kings Coll London, Div Canc Studies Translat Oncol & Urol Res, London SE1 9RT, England..
    Hammar, Niklas
    Karolinska Inst, Inst Environm Med, Unit Epidemiol, SE-17177 Stockholm, Sweden.;AstraZeneca R & D, S-43150 Molndal, Sweden..
    Jungner, Ingmar
    Karolinska Inst, Dept Med, Clin Epidemiol Unit, SE-17177 Stockholm, Sweden.;CALAB Res, SE-17177 Stockholm, Sweden..
    Malmström, Håkan
    Karolinska Inst, Dept Med Epidemiol & Biostat, SE-17177 Stockholm, Sweden..
    Lambe, Mats
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences. Karolinska Inst, Dept Med Epidemiol & Biostat, SE-17177 Stockholm, Sweden..
    Walldius, Göran
    Karolinska Inst, Inst Environm Med, Unit Cardiovasc Epidemiol, SE-17177 Stockholm, Sweden..
    Van Hemelrijck, Mieke
    Kings Coll London, Div Canc Studies Translat Oncol & Urol Res, London SE1 9RT, England.;Karolinska Inst, Inst Environm Med, Unit Epidemiol, SE-17177 Stockholm, Sweden..
    Serum biomarkers to predict risk of testicular and penile cancer in AMORIS2017In: ecancermedicalscience, ISSN 1754-6605, E-ISSN 1754-6605, Vol. 11, 762Article in journal (Refereed)
    Abstract [en]

    Purpose: To evaluate the association between commonly measured serum biomarkers of inflammation and penile and testicular cancer risk in the Swedish Apolipoprotein-related MORtality RISk (AMORIS) study.

    Materials and methods: A total of 205,717 subjects had baseline measurements of C-reactive protein, albumin, and haptoglobin. The association between quartiles and dichotomised values of inflammatory markers and penile and testicular cancer risk were analysed by using multivariate Cox proportional hazard models.

    Results: A total of 125 men were diagnosed with testicular cancer and 50 with penile cancer during a mean follow-up of 20.3 years. No statistically significant trends were seen between serum inflammatory markers and risk of penile cancer, but higher albumin levels increased the risk of testicular cancer [HR for albumin (g/L): 1.10 (95% CI: 1.03-1.18)]. However, this trend was not observed when using medical cut-offs of albumin.

    Conclusions: In the present study, we did not find support for an association between commonly used markers of inflammation and risk of testicular or penile cancer. The role of inflammation may be more complicated and require assessment of more specialised measurements of inflammation in future studies.

  • Rengasamy, Madhumitha
    et al.
    Zhang, Fan
    Vashisht, Ajay
    Song, Won-Min
    Aguilo, Francesca
    Umeå University, Faculty of Medicine, Department of Medical Biosciences.
    Sun, Yifei
    Li, SiDe
    Zhang, Weijia
    Zhang, Bin
    Wohlschlegel, James A.
    Walsh, Martin J.
    The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer2017In: Nucleic Acids Research, ISSN 0305-1048, E-ISSN 1362-4962, Vol. 45, no 19, 11106-11120 p.Article in journal (Refereed)
    Abstract [en]

    We observed overexpression and increased intranuclear accumulation of the PRMT5/WDR77 in breast cancer cell lines relative to immortalized breast epithelial cells. Utilizing mass spectrometry and biochemistry approaches we identified the Zn-finger protein ZNF326, as a novel interaction partner and substrate of the nuclear PRMT5/WDR77 complex. ZNF326 is symmetrically dimethylated at arginine 175 (R175) and this modification is lost in a PRMT5 and WDR77-dependent manner. Loss of PRMT5 or WDR77 in MDA-MB-231 cells leads to defects in alternative splicing, including inclusion of A-T rich exons in target genes, a phenomenon that has previously been observed upon loss of ZNF326. We observed that the alternatively spliced transcripts of a subset of these genes, involved in proliferation and tumor cell migration like REPIN1/AP4, ST3GAL6, TRNAU1AP and PFKM are degraded upon loss of PRMT5. In summary, we have identified a novel mechanism through which the PRMT5/WDR77 complex maintains the balance between splicing and mRNA stability through methylation of ZNF326.

  • Irshad, Mohsin
    Blekinge Institute of Technology, Faculty of Computing, Department of Software Engineering.
    Assessing Reusability in Automated Acceptance Tests2018Licentiate thesis, comprehensive summary (Other academic)
    Abstract [en]

    Context: Automated acceptance tests have become a core practice of agile software development (e.g. Extreme Programming). These tests are closely tied to requirements specifications and these tests provide a mechanism for continuous validation of software requirements. Software reuse has evolved with the introduction of each new reusable artefact (e.g., reuse of code, reuse of frameworks, tools etc.). In this study, we have investigated the reusability of automated acceptance tests keeping in view their close association with textual requirements.

    Objective: As automated acceptance tests are closely related to software requirements, we have used existing research in software engineering to identify reusability related characteristics of software requirements and used these characteristics for automated acceptance tests.This study attempts to address the following aspects: (i) what important reuse characteristics should be considered when measuring reusability of automated acceptance tests? (ii) how reusability can be measured in automated acceptance tests?, and (iii) how cost avoided through reuse of automated acceptance tests can be calculated?

    Method: We have used a combination of research methods to answer different aspects of our study. We started by identifying reusability related characteristics of software requirements, with help of systematic literature review. Later, we tried to identify the reusability related characteristics of defect reports and the process is documented using an experience report. After identifying the characteristics from the previous two studies, we used these characteristics on two case-studies conducted on Behaviour driven development test cases (i.e., acceptance tests of textual nature). We proposed two approaches that can identify the reuse potential of automated acceptance tests and evaluated these approaches in the industry. Later, to calculate the cost avoided through reuse, we proposed and evaluated a method that is applicable to any reusable artifact.

    Results: The results from the systematic literature review shows that text-based requirements reuse approaches are most commonly used in the industry. Structuring these text-based requirements and identifying the reusable requirements by matching are the two commonly used methods for enabling requirements to reuse. The results from the second study, industrial experience report, indicates that defect reports can be formulated in template and defect triage meeting can be used to identify important test-cases related to defect reports. The results from these two studies, text-based requirements reuse approaches and template based defect reports, were included when identifying approaches to measure reuse potential of BDD test-cases. The two proposed approaches, Normalised Compression Distance (NCD) and Similarity Ratio, for measuring reuse potential were evaluated in the industry. The evaluation indicated that Similarity ratio approach performed better than the NCD approach, however, the results from both approaches were comparable with the results gathered with the help of expert analysis. The cost related aspects of reusable acceptance tests were addressed and evaluated using a method that calculates the cost-avoidance through reuse. The industrial evaluation of the method and guidelines show that the method is an artifact independent method. 

    Conclusions: The evidence from this study shows that the automated acceptance tests are reusable, similar to text-based software requirements and their reuse potential can be calculated as well. The industrial evaluation of the three studies (i.e. approaches to measure reuse potential, calculation of cost avoidance and defect reports in triage meetings) shows that the overall results are applicable to the industry. However, further work is required to evaluate the reuse potential of automated acceptance tests in different contexts. 

  • Kotljarchuk, Andrej
    et al.
    Södertörn University, School of Historical and Contemporary Studies, Institute of Contemporary History. Södertörn University, Centre for Baltic and East European Studies (CBEES), Baltic & East European Graduate School (BEEGS).
    Sundström, OlleUmeå universitet.
    Ethnic and Religious Minorities in Stalin’s Soviet Union: New Dimensions of Research2017Collection (editor) (Refereed)
    Abstract [en]

    This anthology presents studies of Stalinism in the ethnic and religious borderlands of the Soviet Union. The authors not only cover hitherto less researched geographical areas, but have also addressed new questions and added new source material. Most of the contributors to this anthology use a micro-historical approach. With this approach, it is not the entire area of the country, with millions of separate individuals that are in focus but rather particular and cohesive ethnic and religious communities.

    Micro-history does not mean ignoring a macro-historical perspective. What happened on the local level had an all-Union context, and communism was a European-wide phenomenon. This means that the history of minorities in the Soviet Union during Stalin’s rule cannot be grasped outside the national and international context; aspects which are also considered in this volume. The chapters of the book are case studies on various minority groups, both ethnic and religious. In this way, the book gives a more complex picture of the causes and effects of the state-run mass violence during Stalinism.

    The publication is the outcome of a multidisciplinary international research network lead by Andrej Kotljarchuk (Södertörn University, Sweden) and Olle Sundström (Umeå University, Sweden) and consisting of specialists from Estonia, France, Germany, Russia, Sweden, Ukraine and the United States. These scholars represent various disciplines: Anthropology, Cultural Studies, History and the History of Religions.

  • Wendin, Karin
    et al.
    Kristianstad University, School of Education and Environment, Avdelningen för Mat- och måltidsvetenskap. Kristianstad University, Research Environment Food and Meals in Everyday Life (MEAL).
    Bredie, Wender
    Danmark.
    Maitre, Isabelle
    Frankrike.
    Matullat, Imke
    Tyskland.
    Olsson, Viktoria
    Kristianstad University, School of Education and Environment, Avdelningen för Mat- och måltidsvetenskap. Kristianstad University, Research Environment Food and Meals in Everyday Life (MEAL).
    Kremer, Stefanie
    Holland.
    Giboreau, Agnes
    Frankrike.
    Ueland, Oydis
    Norge.
    Appetite for life: reflections on how to increase food intake in the elderly2017In: MENU, Journal of Food & Hospitality Research, ISSN 2275-5748, Vol. 6, no November, 25-33 p.Article in journal (Refereed)
    Abstract [en]

    Maintaining appetite for foods at old and very old age is important for keeping a reasonable healthstatus and quality of life in this growing group of citizens. Since the personal health status and livingcondition change for people at higher age a loss of independence in the way they are accustomed toprepare and consume foods is often a consequence. This may lead to changes in consumptionpatterns and a deteriorated living condition. Full attention should be given to different approacheson how quality of life and appetite for food can be maintained in this group of citizens. The presentshort communication addresses this topic from multiple angles and presents the results from adiscussion by experts on the topic.

  • Norén, Fredrik
    Umeå University, Faculty of Arts, Department of culture and media studies. Umeå University, Faculty of Arts, Humlab.
    Information som lösning, information som problem: En digital läsning av tusentals statliga utredningar2016In: Nordicom Information, ISSN 0349-5949, Vol. 38, no 3, 9-26 p.Article in journal (Refereed)
    Abstract [en]

    This article investigates how the Swedish information politics emerged in the twentieth century by analysing thousands of Swedish Governmental Official Reports (8000 reports since 1922). By using methods such as topic modelling with LDA/MALLET, the result shows that a governmental information discourse arose in the 1960s, infiltrating a growing number of political interests, and that the content of the discourse has changed over time.

    One important conclusion highlights digital text methods as a more inductive way of doing content analysis than is commonly practised in media and communication studies. A machine can find patterns in texts that no single person could read in a lifetime. Furthermore, the quantitative approach can generate results that problematise previous – qualitative – research. Digital and quantitative analysis of a huge corpora does not neglect close reading; on the contrary this study shows the necessity of bridging both methods in order to better understand the results.

  • Eklund, Mona
    et al.
    Tjornstrand, Carina
    Sandlund, Mikael
    Umeå University, Faculty of Medicine, Department of Clinical Sciences, Psychiatry.
    Argentzell, Elisabeth
    Effectiveness of Balancing Everyday Life (BEL) versus standard occupational therapy for activity engagement and functioning among people with mental illness - a cluster RCT study2017In: BMC Psychiatry, ISSN 1471-244X, E-ISSN 1471-244X, Vol. 17, 363Article in journal (Refereed)
    Abstract [en]

    Background: Many with a mental illness have an impoverished everyday life with few meaningful activities and a sedentary lifestyle. The study aim was to evaluate the effectiveness of the 16-week Balancing Everyday Life (BEL) program, compared to care as usual (CAU), for people with mental illness in specialized and community-based psychiatric services. The main outcomes concerned different aspects of subjectively evaluated everyday activities, in terms of the engagement and satisfaction they bring, balance among activities, and activity level. Secondary outcomes pertained to various facets of well-being and functioning. It was hypothesized that those who received the BEL intervention would improve more than the comparison group regarding activity, well-being and functioning outcomes.

    Methods: BEL is a group and activity-based lifestyle intervention. CAU entailed active support, mainly standard occupational therapy. The BEL group included 133 participants and the CAU group 93. They completed self-report questionnaires targeting activity and well-being on three occasions – at baseline, after completed intervention (at 16 weeks) and at a six-month follow-up. A research assistant rated the participants’ level of functioning and symptom severity on the same occasions. Non-parametric statistics were used since these instruments produced ordinal data.

    Results: The BEL group improved more than the CAU group from baseline to 16 weeks on primary outcomes in terms of activity engagement (p < 0.001), activity level (p = 0.036) and activity balance (p < 0.042). The BEL group also improved more on the secondary outcomes of symptom severity (p < 0.018) and level of functioning (p < 0.046) from baseline to 16 weeks, but not on well-being. High intra-class correlations (0.12–0.22) indicated clustering effects for symptom severity and level of functioning. The group differences on activity engagement (p = 0.001) and activity level (p = 0.007) remained at the follow-up. The BEL group also improved their well-being (quality of life) more than the CAU group from baseline to the follow-up (p = 0.049). No differences were found at that time for activity balance, level of functioning and symptom severity.

    Conclusion: The BEL program was effective compared to CAU in terms of activity engagement. Their improvements were not, however, greater concerning other subjective perceptions, such as satisfaction with daily activities and self-rated health, and clustering effects lowered the dependability regarding findings of improvements on symptoms and functioning. Although the CAU group had “caught up” at the follow-up, the BEL group had improved more on general quality of life. BEL appeared to be important in shortening the time required for participants to develop their engagement in activity and in attaining improved quality of life in a follow-up perspective.

  • Hugoson, Marlene
    Institute for Language and Folklore, Department of Dialectology and Folklore Research, Uppsala.
    Midwinter Masking: Place and Identity in an Ironworks Community2016In: The Ritual Year 11: Traditions and Transformation. The Yearbook of the SIEF Working Group on the Ritual Year; Proceedings of the Eleventh International Conference of the SIEF Working Group on The Ritual Year, Kazan June 4–7, 2015 / [ed] Guzel Stolyarova, Irina Sedakova & Nina Vlaskina, Kazan — Moscow: University of Kazan — Russian Academy of Sciences , 2016Chapter in book (Refereed)
  • Sobhy, Haitham
    Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine).
    A comparative review of viral entry and attachment during large and giant dsDNA virus infections2017In: Archives of Virology, ISSN 0304-8608, E-ISSN 1432-8798, Vol. 162, no 12, 3567-3585 p.Article, review/survey (Refereed)
    Abstract [en]

    Viruses enter host cells via several mechanisms, including endocytosis, macropinocytosis, and phagocytosis. They can also fuse at the plasma membrane and can spread within the host via cell-to-cell fusion or syncytia. The mechanism used by a given viral strain depends on its external topology and proteome and the type of cell being entered. This comparative review discusses the cellular attachment receptors and entry pathways of dsDNA viruses belonging to the families Adenoviridae, Baculoviridae, Herpesviridae and nucleocytoplasmic large DNA viruses (NCLDVs) belonging to the families Ascoviridae, Asfarviridae, Iridoviridae, Phycodnaviridae, and Poxviridae, and giant viruses belonging to the families Mimiviridae and Marseilleviridae as well as the proposed families Pandoraviridae and Pithoviridae. Although these viruses have several common features (e.g., topology, replication and protein sequence similarities) they utilize different entry pathways to infect wide-range of hosts, including humans, other mammals, invertebrates, fish, protozoa and algae. Similarities and differences between the entry methods used by these virus families are highlighted, with particular emphasis on viral topology and proteins that mediate viral attachment and entry. Cell types that are frequently used to study viral entry are also reviewed, along with other factors that affect virus-host cell interactions.

  • Hugoson, Marlene
    Institute for Language and Folklore, Department of Dialectology and Folklore Research, Uppsala.
    The Politics of Tradition: Folk Healing on Two Continents, Part I2014In: Politics, Feasts, Festivals: Yearbook of the SIEF Working Group on the Ritual Year. Proceedings of the Ninth International Conference of the SIEF Working Group on the Ritual Year / [ed] Gábor Barna & István Povedák, Szeged: Hungarian Academy of Sciences : Department of Ethnology and Cultural Anthropology , 2014, 265-273 p.Chapter in book (Refereed)
  • Linde, Peter
    Blekinge Institute of Technology, The Library.
    BTH Newsletter on Science Publishing and Information about research funding: December 20172017Other (Other (popular science, discussion, etc.))
  • Hugoson, Marlene
    Institute for Language and Folklore, Department of Dialectology and Folklore Research, Uppsala.
    Ritual Healing on Two Continents: Nature, Traditions, and Belief (Part I)2014In: The Ritual Year 8 Migrations: Proceedings of the Eight International Conference of the SIEF Working Group on the Ritual Year / [ed] Dobrinka Parusheva & Lina Gergova, Sofia: Institute of Ethnology and Folklore Studies with Ethnographic Museum at the Bulgarian Academy of Sciences , 2014, 375-387 p.Chapter in book (Refereed)
  • Länsstyrelsen Gävleborg, Länsstyrelsen Gävleborg
    Executive, Länsstyrelser, Länsstyrelsen Gävleborg.
    Gävleborgs län inför klimatförändringarna: Översiktlig klimat- och sårbarhetsanalys med fokus på samhällsplanering2008Report (Other academic)
    Abstract [sv]

    Gävleborgs   län inför klimatförändringarna- Översiktlig klimat- och sårbarhetsanalys med fokus på samhällsplanering

  • Holmgren, Torbjörn
    et al.
    Executive, Länsstyrelser, Länsstyrelsen Gävleborg.
    Ryd, Charlotta
    Executive, Länsstyrelser, Länsstyrelsen Gävleborg.
    Gustafsson, Susanne
    Executive, Länsstyrelser, Länsstyrelsen Gävleborg.
    Klimat- och Energistrategi för Gävleborgs län2008Report (Other academic)
    Abstract [sv]

    Klimat- och Energistrategi för Gävleborgs län

  • Mäkitalo, Astrid
    Executive, Länsstyrelser, Länsstyrelsen Gävleborg. Ljusdal, Bolnäss, Gävle, Sandviken, Hofors, Ockelbo, Söderhamn, Ovanåker, Nordanstig, Hudiksvall.
    Radon: En sammanställning över radonsituationen i Gävleborg2010Report (Other academic)
    Abstract [sv]

    I oktober 2008 skickade Länsstyrelsen i Gävleborg ut en enkät med frågor om

    radonsituationen till samtliga kommuner i länet. Syftet var att få ett underlag och

    en utvärdering av kommunernas arbete med radonfrågan. Kartläggningen ska

    också utgöra kunskapsunderlag för miljömålsuppföljningen. Astrid Mäkitalo på

    Länsstyrelsen Gävleborgs miljöskyddsenhet har sammanställt svaren på frågorna.

    Enkäten bestod av tre olika delar. Del A behandlar det förebyggande arbetet, fysisk

    planering och bygglov samt den befintliga bebyggelsen, del B avser vattenförsörjning

    och i del C övrigt, det vill säga det dominerande radonproblemet samt kommande

    radonkampanjer. Alla kommuner besvarade enkäten.

    9 kommuner uppger att samtliga eller i stort sett samtliga skolor har mätts. Cirka 40

    skolor och förskolor har haft radonhalter över 200 Bq/m

    3. Kommunerna känner enligt

    enkäten till ca 40 fall där åtgärder vidtagits. Alla har kontrollmätts efter åtgärd och 3

    har fortfarande, efter åtgärd, radonhalter över 200 Bq/m

    3. Vi når därmed inte de

    regionala miljömålet om att radonhalten år 2010 ska vara lägre än 200 Bq/m

    3 luft i

    alla skolor och förskolor.

    En mycket stor andel av åtgärdade och kontrollmätta småhus har fortfarande radonhalter

    över 200 Bq/m

    3 i inomhusluften. Detta överskrider det nationella och regionala

    miljömålet som säger att radonhalten i alla bostäder år 2020 är lägre än 200 Bq/m

    3.

    Hur många bostäder som mätts, är utifrån detta material omöjligt att bedöma.

    Hur långt olika kommuner kommit med mätningar i byggnader och vatten varierar.

    Hanteringen av ärenden är olika, likaså hur krav på åtgärder ställs. Svaren visar att

    man i många kommuner har svårt att arbeta med radonproblematiken i den utsträckning

    som man önskar. Mycket arbete med mätningar och åtgärder, både vad gäller bostäder

    och vatten, återstår

  • Hultman, Elin
    Executive, Länsstyrelser, Länsstyrelsen Gävleborg.
    Hartzell, Gustav
    Executive, Länsstyrelser, Länsstyrelsen Gävleborg.
    Sjöberg, Hans
    Executive, Länsstyrelser, Länsstyrelsen Gävleborg.
    Örn, Christer
    Executive, Länsstyrelser, Länsstyrelsen Gävleborg.
    Bristande vattenföring förbi Gävleborgs regleringsdammar2010Report (Other academic)
    Abstract [sv]

    Gävleborgs regionala miljömål

    8.6 Godtagbar minimivattenföring,

    lyder

    ”2010 ska 50 % av alla kraftverk och regleringsdammar ha en, ur biologisk

    mångfald, godtagbar minimivattenföring genom eller förbi respektive anläggning”.

    Målet

    syftar till att främja den biologiska mångfalden genom att förbättra vandringsmöjligheter och

    livsmiljöer för fisk och övriga vattenlevande växter och djur.

    Vattenkraft är en ren och förnybar energikälla med låga utsläpp och mycket liten

    klimatpåverkan men konsekvenserna för landskapet och organismerna i och kring ett utbyggt

    vattendrag är stora. Vissa områden torrläggs, medan andra överdäms, forsar försvinner och

    det blir svårare för fiskar och andra djur och växter att överleva. De flesta stora svenska

    kraftverken byggdes under en tid då samhället inte prioriterade naturvårdsfrågor.

    Länsstyrelsens uppföljning av miljömålet visar att situationen för länets vattendrag är mycket

    allvarlig. Resultatet visar att det vid endast 16 av 142 kraftverksdammar finns en godtagbar

    minimivattenföring. Det motsvarar 11 % vilket är långt ifrån det uppsatta målet om 50 %.

    Vi har i den här studien definierat att en damm har en biologiskt godtagbar

    minimivattenföring när dammens minimitappning är större än eller lika stor som vattendragets

    lågvattenföring. För att urskilja de dammar som har en godtagbar minimivattenföring, har

    studien gjorts i två steg utifrån länets 142 regleringsdammar. I det första steget bedömdes de

    dammar som har nolltappning

    inte ha en biologiskt godtagbar vattenföring. Nolltappning

    betyder att inget vatten alls behöver tappas förbi anläggningen. De 65 urskiljda

    regleringsdammarna bedömdes sedan utifrån dess minimitappning i jämförelse med

    vattendragets normala lågvattenföring. Minimitappning är den minsta vattenföring som

    regleringsdammen måste släppa förbi.

    För att på sikt nå målet krävs ett aktivt arbete från Länsstyrelsen, kommuner och

    Kammarkollegiet för att ta fram underlag och att driva omprövningar av gamla vattendomar i

    syfte att få till stånd ökade minimitappningar förbi dammar och kraftverk. Arbetet bör ske i

    dialog med kraftbolagen. Berörda myndigheter bör också tillsammans med kraftbolagen

    identifiera de dammar som idag inte ger någon större nytta för kraftproduktion och åtgärda

    dessa, t.ex. genom utrivning, så att vattenföringen kan återgå till det ursprungliga flödet.

  • Vesslèn, Göran
    et al.
    Executive, Länsstyrelser, Länsstyrelsen Gävleborg.
    Bengtsson, Johanna
    Executive, Länsstyrelser, Länsstyrelsen Gävleborg.
    Inventering  av blåtryffel (Chamonixia caespitosa) i Gävleborgs län 20082009Report (Other academic)
    Abstract [sv]

    Blåtryffel är en underjordisk svamp som är ca 1-2 x 3-5 centimeter stor. Den är

    tillplattat rundad eller något oregelbunden formad. Systematiskt är den närmast

    släkt med sopparna. Fruktkroppen till svampen känns igen då den skiftar färg

    från vit till blå när den blottläggs.

    Blåtryffeln är klassad som starkt hotad (EN) i den nationella rödlistan. I Sverige

    är arten idag känd från 36 lokaler där skogen inte blivit avverkad. Totalt är

    svampen känd från strax över 50 lokaler i världen. Blåtryffeln bildar mykorrhiza

    med gran och ställer specifika krav på sin livsmiljö. Den hittas i äldre granskogs

    raviner

    med ytligt rörligt markvatten och som har permanent fuktig mark. Granskogen

    ska ha hög bonitet och lång obruten kontinuitet. I den näromliggande

    miljön ska det finnas gott om markbunden död ved samt välutvecklade barr- och

    mossmattor. Denna miljö kan påträffas i bäckraviner och bergsluttningar med

    ytligt rinnande källor. Närvaro av blåtryffel signalerar ett granekosystem vi inte

    har mycket kvar av vare sig i länet eller i landet: äldre ravingranskog med hög

    fuktighet. Den tål inga avverkningar som kan förändra luftfuktigheten på lokalen.

    I blåtryffelns livsmiljö finns ofta flera andra skyddsvärda arter. Blåtryffeln har

    tidigare eftersökts i länet med negativt resultat. Vid 2008 års inventering besöktes

    15 lokaler i Gävleborgs län. Blåtryffel påträffades på två lokaler i länet, båda

    fyndplatserna ligger väster om Ockelbo

  • Bro, Ulla
    et al.
    Executive, Länsstyrelser, Länsstyrelsen Gävleborg.
    von Hofsten, Maria
    Executive, Länsstyrelser, Länsstyrelsen Gävleborg.
    Bräddning av avloppsvatten i Sverige och Gävleborgs län2009Report (Other academic)
    Abstract [sv]

    förslag på havsmiljöåtgärder som Länsstyrelsen lämnade till Naturvårdsverket i november 2007.

    Begreppet bräddning är i rapporten definierat på samma sätt som i föreskrifterna i SNFS 1990:14,

    dvs som utsläpp av avloppsvatten på grund av hydraulisk överbelastning.

    Målsättningen med projektet var att få en samlad bild av omfattningen och effekterna av

    bräddning från avloppsreningsverk regionalt och nationellt. En annan målsättning var att utveckla

    ett systematiskt arbetssätt för att utifrån ett regionalt perspektiv bedöma miljöeffekter av

    bräddning. Detta för att kunna bedöma om åtgärder är kostnadseffektiva i förhållande till

    miljönyttan.

    För den regionala delen har data inhämtats direkt från kommunernas tekniska kontor eller VA-bolag,

    för åren 2003-2007. För att beräkna hur mycket fosfor och kväve från bräddningar som når

    havet har retentionsfaktorer från PLC5 används. Den rapporterade bräddningen i Gävleborgs län

    åren 2003-2007 uppgår totalt till ca 1 350 000 m3. Det innebär en bräddning på ledningsnätet på

    0,07 % av den totala tillrinningen, och en bräddning på avloppsreningsverken på 0,78 % av den

    totala tillrinningen. Under dessa 5 år har bräddningar i Gävleborgs län orsakat nettoutsläpp på ca

    21,7 ton kväve och 3,8 ton fosfor, vilket i genomsnitt motsvarar ca 4,3 ton kväve och 0,8 ton

    fosfor per år.

    I länets större vattendrag har utsläppen av bräddat vatten troligen ingen större betydelse, då det

    förorenade vattnet snabbt spolas bort. Däremot kan vattendragets recipient, i många fall havet,

    påverkas mer. I några känsliga inlandssjöar och vattendrag samt grunda vikar längs kusten kan de

    lokala effekterna bli stora.

    Uppgifter om bräddningar i Sverige 2006 har hämtats från olika källor. Den huvudsakliga källan

    har varit emissionsregistret EMIR. När siffror saknats där har uppgifter om möjligt hämtats från

    Svenskt Vatten. I ett fall har uppgifter hämtats in separat via mail, och för Gävleborgs län har

    uppgifter från den regionala studien använts. Från flera kommuner har det saknats uppgifter om

    bräddad volym eller den mängd fosfor och kväve som släppts ut genom bräddning. Vi har där

    försökt uppskatta dessa genom olika metoder och antaganden som beskrivs i rapporten. För att

    beräkna hur mycket fosfor och kväve från bräddningar som når havet har retentionsfaktorer från

    PLC5 används.

    Nationellt beräknas volymen bräddat vatten 2006 ligga mellan 26 och 30 Mm3. Bräddning vid

    reningsverket uppgår till 1,53 % av den totala tillrinningen till verket, baserat på uppgifter från

    103 reningsverk. Motsvarande siffra för ledningsnätet är 0,6 %, dock baserat på uppgifter från

    endast 9 reningsverk. Bruttoutsläppen av fosfor från bräddningar 2006 beräknas ligga mellan 30

    och 42 ton. Det är mellan 1,4 och 1,9 % av det totala utsläppet från antropogena källor till havet.

    Bruttoutsläppen av kväve till havet 2006 beräknas ligga mellan 220 och 300 ton. Det är ca 0,3 %

    av det totala utsläppet från antropogena källor till havet. Den mängd fosfor och kväve som

    kommer från bräddningar beräknas uppgå till mellan 7,4 och 9,6 % (P) respektive 1,1 och 1,5 %

    (N) av reningsverkens totala utsläpp till havet.

    Det finns stora osäkerheter i beräkningen av bräddningen nationellt och dess utsläpp av fosfor och

    kväve. Dels saknas uppgifter helt från en femtedel av landets kommuner, och mörkertalet för

    bräddningar på ledningsnätet är troligtvis stort. Extrapoleringen av den saknade volymen är också

    gjord med en väldigt grov metod. Dels innebär beräkningarna av fosfor och kväve flera delvis

    grova antaganden och generaliseringar. Med bättre och mer heltäckande rapporteringar och bättre

    kontroll på ledningsnätets bräddpunkter skulle man få en säkrare bild av bräddningens omfattning

    och påverkan.

    Det visade sig svårt att bedöma olika konkreta åtgärders kostnadseffektivitet. Kostnaderna skiljer

    sig åt beroende på platsen och vad som är mest kostnadseffektivt måste därför utredas från fall till

    fall. Ett sätt att arbeta med detta är att säkerställa att alla kommuner upprättar saneringsplaner av

    god kvalitet. Detta kan göras i ett gemensamt tillsynsprojekt inom länet, där kriterier för hur

    saneringsplaner ska tas fram fastställs.

    Ett förslag på systematiskt arbetssätt för insamling av bräddningsdata har tagits fram. Ett

    kostnadseffektivt arbetssätt är att prioritera arbetet utifrån miljönytta. I förslaget görs

    bedömningen av bräddningens miljöeffekter utifrån recipienternas känslighet. För att djupare

    kunna bedöma miljöeffekterna i en särskild recipient eller ett särskilt vattensystem behöver en

    mer grundläggande modellering av näringsbelastningen göras.

    En ytterligare slutsats som dragits under projektet är att man, eftersom det finns flera definitioner

    av begreppet bräddning, måste vara väldigt noga med att tydliggöra vad man menar i

    kommunikation med andra.

     

  • Lund Ohlsson, Marie
    et al.
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Danvind, Jonas
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Quality Technology and Management, Mechanical Engineering and Mathematics. Swedish Parasport Federation.
    Holmberg, L. Joakim
    Linköping University.
    LUMBAR SPINE REACTION FORCES IN SEATED PARA-SPORT: CROSS-COUNTRY SIT-SKIING2017In: Brisbane 2017: Abstract book, 2017Conference paper (Refereed)
    Abstract [en]

    INTRODUCTION

    For wheel-chair users shoulder injuries [1] and lower back injuries [2] are common. Lower back kyphosis of the spine, increases the anterior shear force in the lower back [3] and increases the risk of shoulder injuries [4].

     

    Cross-country sit-skiing (CCSS) is an endurance sport where the athlete is seated in a sledge mounted on a pair of skis and propel themselves by poling with a pair of sticks. This sport creates more equal loading on the muscles around the shoulder than wheel-chair rolling [5] which is positive in an injury perspective for the gleno-humeral joint [1].

     

    Athletes in CCSS with reduced trunk muscle control often sits in a sledge with their knees higher than their hips (KH) and a backrest. This position is hypothesized to be associated with spinal kyphosis and hence an increased risk of injuries. Therefore we have created a new sitting position with knees lower than hips (KL) with the trunk restrained on a frontal support.

     

    The aim of this study was to compute the L4/L5 joint reactions and compare the results between the positions KH and KL.

    METHODS

    Five female abled-bodied cross-country skiing athletes (62.6 ± 8.1kg, 1.67 ± 0.05m)  performed one exercise test session in each sitting position; The sessions included a sub-maximal incremental test, including 4-6 exercise levels of 3 min (exercise intensity nr 4, 37W, reflected race-pace) and a maximal time-trial (MAX) of 3 min on a commercial skiing ergometer (ThoraxTrainer A/S, Denmark).

     

    Full-body kinematics (Qualisys AB, Sweden) and pole forces (Biovision, Germany) were measured in 200 Hz. These data served as input to inverse dynamic simulations in The AnyBody Modelling system (AMS 6.0, Anybody Technology A/S, Denmark). For each participant and sitting position, simulations were made for exercise intensity 37W and MAX over four poling cycles using a 5th order polynomial muscle recruitment criteria. Compression forces and anterior shear forces between L4 and L5 were computed and normalized to each participant’s standing joint reactions. Data were compared pair-wise between the two sitting positions.

     

    Statistical significance (p ≤ 0.05) were marked with asterisk (*). Tendency of difference (0.05 ≤ p < 0.10) were marked (ǂ).

     

    RESULTS AND DISCUSSION

    Performance was higher in position KH (KL: 0.77±0.08 W/kg, KH: 1.00±0.14 W/kg, p < 0.01). No difference were observed in cycle length or cycle time. Kinematics results showed that KL had less spine flexion and range of motion in flexion. KH showed higher mean pole force in 37W and tendency of higher peak pole force in MAX.

     

    In standing, L4/L5 compression and anterior shear forces were 354 ± 45N and 32 ± 11N respectively. The normalized L4/L5 reaction forces (fig. 1) were larger in KH, especially during MAX intensity due to higher power. For equal power output, 37W, the mean anterior shear force was larger in KH and the mean compression force showed tendency of larger in KH (p=0.077).

     

    Figure 1: Normalized joint reaction forces, compression and anterior shear forces, between vertebrae L4/L5 for the two sitting positions KH and KL with trunk restraint. Min – minimal force, Maximal force and Mean – mean force over the four poling cycles.

     

    CONCLUSIONS

    Based on inverse-dynamics musculo-skeletal simulations of 5 abled-bodied athletes, the sitting position KL with frontal restraint reduced the compression and shear force between the L4/L5 vertebrae but impeded performance. This study shows the difficulty of comparing performance and safety in the same piece of equipment.

     

    ACKNOWLEDGEMENTS

    The authors acknowledge the Rolf & Gunilla Enström foundation and the Promobilia foundation, Sweden, for financial support, and the Ableway AB (Sweden) for construction of the sledges.

     

    REFERENCES

    1. Burnham RS, et al., Am J Sports Med, 21: 238-242, 1993.
    2. Thyberg M, et al., Disabil rehabil. 23:677-682, 2001.
    3. McGill SM, et al., Clin Biomech, 15: 777-780, 2000.
    4. Samuelsson KA, et al., J Rehabil Res Dev, 41: 65-74, 2004.
    5. Bjerkefors A, et al., Int J Sports Med, 34: 176-182, 2013.
  • Kellner, Olle
    Executive, Länsstyrelser, Länsstyrelsen Gävleborg.
    Kempe, Göran
    Institutionen för skoglig resurshushållning, Umeå.
    Mer träd på myrana: Igenväxning de senaste 20 åren2010Report (Other academic)
    Abstract [sv]

    Mer träd på myrana igenväxning de senaste 20 åren

  • Brage, Markus
    Executive, Länsstyrelser, Länsstyrelsen Gävleborg.
    Svartån och dess omgivning: En beskrivning och sammanställning av befintligt material2008Report (Other academic)
    Abstract [sv]

    Svartån och dess omgivning- En beskrivning och sammanställning av befintligt material

  • Hugoson, Marlene
    Institute for Language and Folklore, Department of Dialectology and Folklore Research, Uppsala.
    You are Cordially Invited to...: The Distanced Participation in a Royal Wedding2012In: The Interplay of Performances, Performers, Researchers, and Heritages: Proceedings of the Seventh International Conference of The SIEF Working Group on The Ritual Year, Ljubljana November 10-13, 2011 / [ed] Jurij Fikfak & Sébastien Fournier, Ljubljana: Institute of Slovenian Ethnology at ZRC SAZU , 2012, 197-207 p.Chapter in book (Refereed)
  • Jonsson, Gunilla
    Executive, Länsstyrelser, Länsstyrelsen Gävleborg.
    Når vi de regionala miljömålen?: Uppföljning i Gävleborgs län2008Report (Other academic)
    Abstract [sv]

    Når vi de regionala miljömålen? Uppföljning i Gävleborgs län